| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Demeclocycline_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.119595 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.107704 |
| CAPRIN2 | caprin family member 2 | 0.0991284 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0831995 |
| DST | dystonin | 0.0772125 |
| RPS12 | ribosomal protein S12 | 0.0695102 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0664859 |
| HLA-B | major histocompatibility complex, class I, B | 0.0644191 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0643601 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0597389 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0585668 |
| TP63 | tumor protein p63 | 0.0560994 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0529795 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0515553 |
| RPL31 | ribosomal protein L31 | 0.0501216 |
| VCL | vinculin | 0.0458686 |
| PDE10A | phosphodiesterase 10A | 0.0455137 |
| RPS8 | ribosomal protein S8 | 0.0454248 |
| RPL12 | ribosomal protein L12 | 0.043374 |
| RPL37A | ribosomal protein L37a | 0.0427322 |
| CD44 | CD44 molecule (Indian blood group) | 0.0412391 |
| INTS6 | integrator complex subunit 6 | 0.0405512 |
| RPL26 | ribosomal protein L26 | 0.0401942 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0396913 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0395031 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0388344 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0377496 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0350926 |
| PRELID2 | PRELI domain containing 2 | 0.0334019 |
| RPS17 | ribosomal protein S17 | 0.0331791 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0331726 |
| RPL36 | ribosomal protein L36 | 0.032357 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0319005 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0318954 |
| CADM2 | cell adhesion molecule 2 | 0.0311284 |
| RPS10 | ribosomal protein S10 | 0.0299765 |
| RPL38 | ribosomal protein L38 | 0.0299746 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0294178 |
| HDAC9 | histone deacetylase 9 | 0.0293226 |
| RUNX1 | runt-related transcription factor 1 | 0.0291625 |
| B2M | beta-2-microglobulin | 0.0287764 |
| FMNL2 | formin-like 2 | 0.0282523 |
| RPL37 | ribosomal protein L37 | 0.0281082 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.027017 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0266005 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0263187 |
| ASPH | aspartate beta-hydroxylase | 0.0239302 |
| RPS25 | ribosomal protein S25 | 0.023751 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0236085 |
| HLA-A | major histocompatibility complex, class I, A | 0.0235253 |
| SP100 | SP100 nuclear antigen | 0.0233542 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0227743 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0227642 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0226889 |
| PRKCE | protein kinase C, epsilon | 0.0225704 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0225292 |
| DNER | delta/notch-like EGF repeat containing | 0.0214265 |
| RPL36A | ribosomal protein L36a | 0.0212584 |
| VEGFC | vascular endothelial growth factor C | 0.0210347 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0204205 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0203261 |
| HOMER1 | homer scaffolding protein 1 | 0.0200636 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0200339 |
| PLSCR1 | phospholipid scramblase 1 | 0.0199198 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0198764 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0195606 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0193833 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0192963 |
| CMIP | c-Maf inducing protein | 0.0191243 |
| RAD51B | RAD51 paralog B | 0.0190437 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0190393 |
| WDR27 | WD repeat domain 27 | 0.0189153 |
| RPS13 | ribosomal protein S13 | 0.018372 |
| RPL11 | ribosomal protein L11 | 0.0181403 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0181284 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0181085 |
| RPS29 | ribosomal protein S29 | 0.0179436 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0177847 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0177572 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0176921 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0175403 |
| NEK10 | NIMA-related kinase 10 | 0.0173868 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0173493 |
| RPL27 | ribosomal protein L27 | 0.0172692 |
| AEBP2 | AE binding protein 2 | 0.0171881 |
| RPS3 | ribosomal protein S3 | 0.0171594 |
| LRRC49 | leucine rich repeat containing 49 | 0.0169802 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0166742 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0165392 |
| RPLP2 | ribosomal protein, large, P2 | 0.0165241 |
| SLK | STE20-like kinase | 0.0162974 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0162371 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0160617 |
| EGFR | epidermal growth factor receptor | 0.0160437 |
| RCOR1 | REST corepressor 1 | 0.015951 |
| UBAP2 | ubiquitin associated protein 2 | 0.0159185 |
| RPL28 | ribosomal protein L28 | 0.0155245 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0155157 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0154163 |
| VMP1 | vacuole membrane protein 1 | 0.0154027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.249306 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182292 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.181509 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153889 |
| TMSB4X | thymosin beta 4, X-linked | -0.116634 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.11271 |
| RAI1 | retinoic acid induced 1 | -0.1093 |
| MT2A | metallothionein 2A | -0.107142 |
| PTMA | prothymosin, alpha | -0.105528 |
| TXNRD1 | thioredoxin reductase 1 | -0.0992412 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0926376 |
| MT1X | metallothionein 1X | -0.0874229 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.074309 |
| EZR | ezrin | -0.0734353 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0734193 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0681627 |
| ACTG1 | actin gamma 1 | -0.066119 |
| TMSB10 | thymosin beta 10 | -0.0645048 |
| CENPF | centromere protein F, 350/400kDa | -0.0644446 |
| MKI67 | marker of proliferation Ki-67 | -0.0638705 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0599873 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0590921 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0584079 |
| PGK1 | phosphoglycerate kinase 1 | -0.0562823 |
| ANXA1 | annexin A1 | -0.0516263 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0505648 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0497469 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0484072 |
| SEPTIN7 | septin 7 | -0.0451523 |
| RTN4 | reticulon 4 | -0.0451302 |
| POTEF | POTE ankyrin domain family, member F | -0.0450294 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0448679 |
| USP34 | ubiquitin specific peptidase 34 | -0.0446417 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0441721 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0416068 |
| CANX | calnexin | -0.0408004 |
| XPO1 | exportin 1 | -0.0388082 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0386439 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0385671 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0384528 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0384294 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0379344 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0368744 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0367519 |
| YBX1 | Y box binding protein 1 | -0.0366899 |
| WDR45B | WD repeat domain 45B | -0.0355531 |
| FLNB | filamin B, beta | -0.0354625 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0350962 |
| ZFR | zinc finger RNA binding protein | -0.0344149 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0340924 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.034033 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0338443 |
| SRGN | serglycin | -0.033676 |
| ANLN | anillin, actin binding protein | -0.0335758 |
| RBM25 | RNA binding motif protein 25 | -0.0333449 |
| LDHA | lactate dehydrogenase A | -0.0333386 |
| AHNAK | AHNAK nucleoprotein | -0.0332814 |
| APP | amyloid beta (A4) precursor protein | -0.0330921 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0326377 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0316297 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0312785 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0308605 |
| EGR1 | early growth response 1 | -0.0306705 |
| RPL5 | ribosomal protein L5 | -0.0306001 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0305601 |
| YBX3 | Y box binding protein 3 | -0.030315 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0302551 |
| DIAPH3 | diaphanous-related formin 3 | -0.0296656 |
| UBC | ubiquitin C | -0.0295673 |
| TUBB | tubulin, beta class I | -0.0293884 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0292445 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0288617 |
| NUP58 | nucleoporin 58 | -0.0288277 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0287332 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286348 |
| TMEM123 | transmembrane protein 123 | -0.0286077 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0285678 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0283491 |
| RBM39 | RNA binding motif protein 39 | -0.0283339 |
| POM121 | POM121 transmembrane nucleoporin | -0.0283099 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0283002 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0280341 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0278913 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0278696 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0278396 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0273079 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0272661 |
| S100A10 | S100 calcium binding protein A10 | -0.0272599 |
| RLF | rearranged L-myc fusion | -0.027112 |
| FOSL1 | FOS-like antigen 1 | -0.0269222 |
| MTF2 | metal response element binding transcription factor 2 | -0.0264913 |
| MATR3 | matrin 3 | -0.0264783 |
| EMP1 | epithelial membrane protein 1 | -0.0264477 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264168 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263738 |
| HDLBP | high density lipoprotein binding protein | -0.0263551 |
| TMEM41B | transmembrane protein 41B | -0.0254883 |
| ZNF217 | zinc finger protein 217 | -0.0251142 |
| GNAS | GNAS complex locus | -0.0250357 |
| RRM2 | ribonucleotide reductase M2 | -0.0249037 |
