| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.139082 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.129473 |
| TXNRD1 | thioredoxin reductase 1 | 0.116362 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0934296 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0877594 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0635268 |
| HMGA2 | high mobility group AT-hook 2 | 0.0633413 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0627344 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0599486 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0581823 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.057618 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0565312 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0508312 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0508225 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0508007 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0480356 |
| SNX9 | sorting nexin 9 | 0.0459028 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0457002 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0439881 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0427427 |
| CANX | calnexin | 0.0424861 |
| FNIP1 | folliculin interacting protein 1 | 0.0419083 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0417204 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0416277 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.040687 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0396744 |
| IL6ST | interleukin 6 signal transducer | 0.0391922 |
| SMAD3 | SMAD family member 3 | 0.0391907 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0390438 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0377686 |
| CCNI | cyclin I | 0.0370216 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.036926 |
| FNDC3A | fibronectin type III domain containing 3A | 0.036728 |
| ATXN1 | ataxin 1 | 0.0360858 |
| KYNU | kynureninase | 0.0359781 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0359314 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0358281 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0357454 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0352506 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0351473 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0349448 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0348911 |
| ASPH | aspartate beta-hydroxylase | 0.0345447 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0344129 |
| MMP1 | matrix metallopeptidase 1 | 0.0341505 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0332076 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0331442 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0328342 |
| INHBA | inhibin, beta A | 0.0324386 |
| CERT1 | ceramide transporter 1 | 0.0321728 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0319325 |
| RBM39 | RNA binding motif protein 39 | 0.0318242 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0317867 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0317578 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.031749 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0316915 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0316332 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0315537 |
| LMO7 | LIM domain 7 | 0.0314894 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0311614 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0311477 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0311266 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0307713 |
| NCKAP1 | NCK-associated protein 1 | 0.0307638 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0307442 |
| DUSP5 | dual specificity phosphatase 5 | 0.0305308 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0303976 |
| TOP1 | topoisomerase (DNA) I | 0.0303149 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0302846 |
| FAT1 | FAT atypical cadherin 1 | 0.0301693 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.030135 |
| TUSC3 | tumor suppressor candidate 3 | 0.0300879 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0299692 |
| JAK1 | Janus kinase 1 | 0.0298616 |
| CLTC | clathrin, heavy chain (Hc) | 0.029801 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0294872 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0294649 |
| CALU | calumenin | 0.029391 |
| TPD52 | tumor protein D52 | 0.0291475 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0290089 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0289364 |
| ZFHX3 | zinc finger homeobox 3 | 0.0281286 |
| MYO1E | myosin IE | 0.0278988 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.027765 |
| EGFR | epidermal growth factor receptor | 0.0277119 |
| DUSP16 | dual specificity phosphatase 16 | 0.0276386 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0274328 |
| TJP1 | tight junction protein 1 | 0.0273457 |
| TNPO1 | transportin 1 | 0.0271949 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0271878 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0269099 |
| MYO1D | myosin ID | 0.026899 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0268891 |
| OGA | O-GlcNAcase | 0.0267237 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0266932 |
| ANXA2 | annexin A2 | 0.0265333 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0265174 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0265053 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0264671 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0264399 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131254 |
| TMSB10 | thymosin beta 10 | -0.0869308 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0844003 |
| PTMA | prothymosin, alpha | -0.0779654 |
| MUC16 | mucin 16, cell surface associated | -0.0730262 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0688322 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0627043 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0626097 |
| RPL15 | ribosomal protein L15 | -0.0616378 |
| TPM4 | tropomyosin 4 | -0.0610831 |
| RPS12 | ribosomal protein S12 | -0.0601212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0596381 |
| RPL31 | ribosomal protein L31 | -0.0573582 |
| RPS16 | ribosomal protein S16 | -0.0559869 |
| RPL37A | ribosomal protein L37a | -0.0557472 |
| S100A9 | S100 calcium binding protein A9 | -0.0554082 |
| S100A6 | S100 calcium binding protein A6 | -0.0553816 |
| RPLP0 | ribosomal protein, large, P0 | -0.0520112 |
| RPL12 | ribosomal protein L12 | -0.0518531 |
| RPS20 | ribosomal protein S20 | -0.0516466 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0515224 |
| RPS25 | ribosomal protein S25 | -0.0511842 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0496035 |
| RPL35A | ribosomal protein L35a | -0.0490168 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0477183 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0473514 |
| NDRG1 | N-myc downstream regulated 1 | -0.0469252 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0463176 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0449129 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0443585 |
| STC1 | stanniocalcin 1 | -0.0440299 |
| RPS6 | ribosomal protein S6 | -0.0439667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0435512 |
| UBC | ubiquitin C | -0.0431965 |
| FTL | ferritin, light polypeptide | -0.0429664 |
| PDE10A | phosphodiesterase 10A | -0.042433 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0418632 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0417338 |
| HLA-A | major histocompatibility complex, class I, A | -0.0416901 |
| POTEF | POTE ankyrin domain family, member F | -0.0416373 |
| SRPK2 | SRSF protein kinase 2 | -0.0414571 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0409397 |
| RPS27A | ribosomal protein S27a | -0.0404214 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0391687 |
| RPL36 | ribosomal protein L36 | -0.0384752 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0373017 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0368359 |
| RPL26 | ribosomal protein L26 | -0.0367064 |
| RPLP2 | ribosomal protein, large, P2 | -0.0365921 |
| RPS3 | ribosomal protein S3 | -0.036354 |
| USP34 | ubiquitin specific peptidase 34 | -0.0362372 |
| RBM47 | RNA binding motif protein 47 | -0.0360321 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0358516 |
| KRT19 | keratin 19, type I | -0.0358332 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0353832 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0338507 |
| RHOA | ras homolog family member A | -0.0331604 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0328162 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0324742 |
| RPS29 | ribosomal protein S29 | -0.0317029 |
| RPL35 | ribosomal protein L35 | -0.0313892 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0313451 |
| KRT17 | keratin 17, type I | -0.031254 |
| HDAC9 | histone deacetylase 9 | -0.0309225 |
| HLA-B | major histocompatibility complex, class I, B | -0.0301493 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0296665 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0294578 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0291707 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0291452 |
| RPS27 | ribosomal protein S27 | -0.0290825 |
| SVIL | supervillin | -0.0290383 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0289284 |
| EZR | ezrin | -0.0288541 |
| RPS19 | ribosomal protein S19 | -0.028739 |
| RPS8 | ribosomal protein S8 | -0.0286519 |
| RPS24 | ribosomal protein S24 | -0.0286511 |
| RPL34 | ribosomal protein L34 | -0.0285009 |
| RPS17 | ribosomal protein S17 | -0.0278162 |
| SSH2 | slingshot protein phosphatase 2 | -0.0273931 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0273339 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0272758 |
| RCOR1 | REST corepressor 1 | -0.027173 |
| RPS5 | ribosomal protein S5 | -0.0271632 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0271169 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0270332 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0269101 |
| RPL8 | ribosomal protein L8 | -0.0268928 |
| RRBP1 | ribosome binding protein 1 | -0.0268883 |
| KIF5B | kinesin family member 5B | -0.0265924 |
| GPHN | gephyrin | -0.0263322 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0262661 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0261584 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0261172 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0260737 |
| CSTB | cystatin B (stefin B) | -0.0253968 |
| PARD3 | par-3 family cell polarity regulator | -0.0250777 |
| CALD1 | caldesmon 1 | -0.0250531 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0250496 |
| RPS11 | ribosomal protein S11 | -0.0250046 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0249855 |
