| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117963 |
| NTM | neurotrimin | 0.115602 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.108308 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.107498 |
| RASAL2 | RAS protein activator like 2 | 0.104434 |
| COL11A1 | collagen, type XI, alpha 1 | 0.10432 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0938101 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0840708 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0764082 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0719579 |
| WWC2 | WW and C2 domain containing 2 | 0.0641028 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0614489 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0612122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0588365 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0576804 |
| ATXN2 | ataxin 2 | 0.056377 |
| ANK2 | ankyrin 2, neuronal | 0.0556582 |
| PRKD1 | protein kinase D1 | 0.0552294 |
| UTRN | utrophin | 0.0551862 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.054297 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.052244 |
| RPS12 | ribosomal protein S12 | 0.0516975 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.05153 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0489915 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0476761 |
| TENM2 | teneurin transmembrane protein 2 | 0.0473438 |
| BPTF | bromodomain PHD finger transcription factor | 0.0464143 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.04621 |
| CALR | calreticulin | 0.0455059 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0452041 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0450667 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0450154 |
| SMYD3 | SET and MYND domain containing 3 | 0.0443406 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0442127 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0429601 |
| SBF2 | SET binding factor 2 | 0.0427011 |
| SNX6 | sorting nexin 6 | 0.0425208 |
| USP47 | ubiquitin specific peptidase 47 | 0.041902 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0417203 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0414166 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0409655 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0400529 |
| HDAC9 | histone deacetylase 9 | 0.0399283 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0393345 |
| LRRC4C | leucine rich repeat containing 4C | 0.038864 |
| INTS6 | integrator complex subunit 6 | 0.0381223 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0362768 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0361463 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0360958 |
| RPS3 | ribosomal protein S3 | 0.0360721 |
| TNPO1 | transportin 1 | 0.03543 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0350092 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348713 |
| SKIL | SKI-like proto-oncogene | 0.0344076 |
| PRTG | protogenin | 0.0342351 |
| LDHA | lactate dehydrogenase A | 0.0338315 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0336763 |
| CLOCK | clock circadian regulator | 0.0334678 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0333987 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0328584 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0325319 |
| DENND4A | DENN/MADD domain containing 4A | 0.0312936 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0311066 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0310139 |
| USP25 | ubiquitin specific peptidase 25 | 0.0307123 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0306728 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0304548 |
| THOC2 | THO complex 2 | 0.0303596 |
| ZNF638 | zinc finger protein 638 | 0.0302233 |
| RPS8 | ribosomal protein S8 | 0.0299943 |
| FOXO1 | forkhead box O1 | 0.0299512 |
| HDAC8 | histone deacetylase 8 | 0.0298475 |
| CADM2 | cell adhesion molecule 2 | 0.0297578 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.02971 |
| STAG2 | stromal antigen 2 | 0.0297017 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0295212 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0294283 |
| TUT4 | terminal uridylyl transferase 4 | 0.0293092 |
| RPS25 | ribosomal protein S25 | 0.0292978 |
| TCF12 | transcription factor 12 | 0.029269 |
| CDH19 | cadherin 19, type 2 | 0.0291691 |
| CEP350 | centrosomal protein 350kDa | 0.0289045 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0286101 |
| ERBIN | erbb2 interacting protein | 0.0284733 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0284215 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0277142 |
| OGA | O-GlcNAcase | 0.0277085 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.02754 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0274603 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0274164 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0273393 |
| ITSN2 | intersectin 2 | 0.0269786 |
| RPLP0 | ribosomal protein, large, P0 | 0.0268848 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0267308 |
| ENO1 | enolase 1, (alpha) | 0.0266611 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0266005 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.026551 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 | 0.0264982 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.026447 |
| PLCB4 | phospholipase C, beta 4 | 0.0264261 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.105812 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0951968 |
| TMSB4X | thymosin beta 4, X-linked | -0.0947998 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0855326 |
| VIM | vimentin | -0.0791937 |
| ZNF292 | zinc finger protein 292 | -0.0747518 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0723207 |
| THBS1 | thrombospondin 1 | -0.0612865 |
| CCDC102B | coiled-coil domain containing 102B | -0.0595402 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0582028 |
| GPC3 | glypican 3 | -0.0566101 |
| RAD51B | RAD51 paralog B | -0.0551381 |
| RTN4 | reticulon 4 | -0.0549544 |
| EMP1 | epithelial membrane protein 1 | -0.053391 |
| ACTN4 | actinin, alpha 4 | -0.0529279 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0525707 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0511269 |
| ANXA2 | annexin A2 | -0.050518 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0482295 |
| RFX7 | regulatory factor X, 7 | -0.047169 |
| PLPP1 | phospholipid phosphatase 1 | -0.0462429 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0444526 |
| CXADR | coxsackie virus and adenovirus receptor | -0.044398 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0438228 |
| USP3 | ubiquitin specific peptidase 3 | -0.0427265 |
| POTEF | POTE ankyrin domain family, member F | -0.0421711 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0414315 |
| DEK | DEK proto-oncogene | -0.0411986 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0411272 |
| ENAH | enabled homolog (Drosophila) | -0.0405393 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0403419 |
| SPAG9 | sperm associated antigen 9 | -0.0402287 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401913 |
| OLA1 | Obg-like ATPase 1 | -0.0385314 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0383604 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0371422 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0371144 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0363974 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0362892 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0360355 |
| MATR3 | matrin 3 | -0.0359431 |
| CBX3 | chromobox homolog 3 | -0.0355677 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0352095 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0349793 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0346924 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0342229 |
| TMEM64 | transmembrane protein 64 | -0.0339131 |
| FAM171B | family with sequence similarity 171, member B | -0.0338115 |
| PDGFC | platelet derived growth factor C | -0.0328315 |
| PEG10 | paternally expressed 10 | -0.0326227 |
| CENPF | centromere protein F, 350/400kDa | -0.0322607 |
| MKI67 | marker of proliferation Ki-67 | -0.0321454 |
| MED12L | mediator complex subunit 12-like | -0.0318869 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -0.0318493 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0314073 |
| ACTG1 | actin gamma 1 | -0.031206 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0309711 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0307839 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0306742 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0305426 |
| SEPTIN7 | septin 7 | -0.0303276 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0300476 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0299903 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0299266 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0298799 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0298645 |
| MPG | N-methylpurine-DNA glycosylase | -0.0298321 |
| CBX1 | chromobox homolog 1 | -0.0296816 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0296003 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0294252 |
| CPA6 | carboxypeptidase A6 | -0.0293802 |
| PTMA | prothymosin, alpha | -0.0291611 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0290927 |
| RDX | radixin | -0.0290766 |
| TMSB10 | thymosin beta 10 | -0.0290255 |
| QKI | QKI, KH domain containing, RNA binding | -0.0289923 |
| KLHL5 | kelch-like family member 5 | -0.0289082 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0288568 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0287271 |
| COL1A2 | collagen, type I, alpha 2 | -0.0285338 |
| ZNF462 | zinc finger protein 462 | -0.028323 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0282468 |
| HMGB2 | high mobility group box 2 | -0.0281515 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0281291 |
| FRMD5 | FERM domain containing 5 | -0.0278625 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.0277407 |
| RLF | rearranged L-myc fusion | -0.0274248 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0273603 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0272684 |
| MMS22L | MMS22-like, DNA repair protein | -0.0272216 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0272127 |
| TMEM123 | transmembrane protein 123 | -0.0272108 |
| RTF2 | replication termination factor 2 | -0.0272082 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0270977 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0268738 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0267779 |
| RHEB | Ras homolog enriched in brain | -0.0265956 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0264838 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0264287 |
| BTG3 | BTG family, member 3 | -0.0262983 |
