| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0900138 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0880845 |
| HDAC9 | histone deacetylase 9 | 0.0822263 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0791039 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.078261 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0769252 |
| ZNF608 | zinc finger protein 608 | 0.0744256 |
| TXNIP | thioredoxin interacting protein | 0.068483 |
| ZNF292 | zinc finger protein 292 | 0.0650139 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0629028 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0606289 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0590017 |
| JMJD1C | jumonji domain containing 1C | 0.0573364 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0571571 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0568621 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0567994 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0523755 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0507074 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0505609 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0498182 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0483531 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0468153 |
| QKI | QKI, KH domain containing, RNA binding | 0.046322 |
| RNF145 | ring finger protein 145 | 0.045396 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0452151 |
| CRY1 | cryptochrome circadian clock 1 | 0.0451253 |
| CDC73 | cell division cycle 73 | 0.0438927 |
| NCKAP1 | NCK-associated protein 1 | 0.0432997 |
| PDGFC | platelet derived growth factor C | 0.0424871 |
| RTN4 | reticulon 4 | 0.0418238 |
| NUP58 | nucleoporin 58 | 0.0417832 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0415045 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0412387 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.040712 |
| PHF3 | PHD finger protein 3 | 0.0399629 |
| PTK2 | protein tyrosine kinase 2 | 0.0399087 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0395859 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0395651 |
| PARD3 | par-3 family cell polarity regulator | 0.0394709 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0389865 |
| SPAG9 | sperm associated antigen 9 | 0.0388755 |
| SMYD3 | SET and MYND domain containing 3 | 0.0379517 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0379042 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0377229 |
| MED13L | mediator complex subunit 13-like | 0.0375334 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0374711 |
| JUN | jun proto-oncogene | 0.0374398 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0373802 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0369418 |
| ANXA1 | annexin A1 | 0.0369275 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0367977 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0362644 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0361944 |
| SETD2 | SET domain containing 2 | 0.0358692 |
| CD47 | CD47 molecule | 0.0355949 |
| ATOSA | atos homolog A | 0.0350303 |
| YTHDC1 | YTH domain containing 1 | 0.0345049 |
| YAP1 | Yes-associated protein 1 | 0.0340651 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335723 |
| USP34 | ubiquitin specific peptidase 34 | 0.0329906 |
| CCNL1 | cyclin L1 | 0.032861 |
| KIF5B | kinesin family member 5B | 0.0326537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0324568 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0324045 |
| TMF1 | TATA element modulatory factor 1 | 0.0319605 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.031926 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0318776 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0317578 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0316899 |
| CEP350 | centrosomal protein 350kDa | 0.0316127 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0314846 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0312701 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0309381 |
| SEPTIN11 | septin 11 | 0.0308246 |
| MATR3 | matrin 3 | 0.0304885 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0303416 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0300155 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0298746 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0296631 |
| COG5 | component of oligomeric golgi complex 5 | 0.0296125 |
| TFG | TRK-fused gene | 0.0295769 |
| UBQLN1 | ubiquilin 1 | 0.0294286 |
| TLK1 | tousled-like kinase 1 | 0.0293312 |
| PGK1 | phosphoglycerate kinase 1 | 0.0292881 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0292519 |
| FAM13A | family with sequence similarity 13, member A | 0.0291862 |
| LPIN2 | lipin 2 | 0.0289126 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0288707 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0288418 |
| RBM39 | RNA binding motif protein 39 | 0.0288402 |
| ZNF148 | zinc finger protein 148 | 0.0287853 |
| ANK2 | ankyrin 2, neuronal | 0.0285229 |
| OGA | O-GlcNAcase | 0.0283863 |
| RLF | rearranged L-myc fusion | 0.028333 |
| PLPP3 | phospholipid phosphatase 3 | 0.0283035 |
| NCOR1 | nuclear receptor corepressor 1 | 0.028267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0282484 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0280043 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0279799 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0279647 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.223758 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202677 |
| PKM | pyruvate kinase, muscle | -0.102004 |
| RPS6 | ribosomal protein S6 | -0.100381 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0734523 |
| AHNAK | AHNAK nucleoprotein | -0.0731466 |
| GSE1 | Gse1 coiled-coil protein | -0.071986 |
| ACTG1 | actin gamma 1 | -0.0690194 |
| RPL35A | ribosomal protein L35a | -0.0683685 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0680073 |
| TJP1 | tight junction protein 1 | -0.0670604 |
| BMP10 | bone morphogenetic protein 10 | -0.0645057 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0617761 |
| POTEF | POTE ankyrin domain family, member F | -0.0609615 |
| RPLP1 | ribosomal protein, large, P1 | -0.0571878 |
| CCND1 | cyclin D1 | -0.0565436 |
| RPS19 | ribosomal protein S19 | -0.0557398 |
| RPS8 | ribosomal protein S8 | -0.0544932 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0472617 |
| MKI67 | marker of proliferation Ki-67 | -0.0470851 |
| VCL | vinculin | -0.0468996 |
| S100A4 | S100 calcium binding protein A4 | -0.04676 |
| GLI2 | GLI family zinc finger 2 | -0.0457331 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0451063 |
| GLI3 | GLI family zinc finger 3 | -0.041963 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0409957 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0404134 |
| SMC4 | structural maintenance of chromosomes 4 | -0.039959 |
| CENPF | centromere protein F, 350/400kDa | -0.0396663 |
| RPLP2 | ribosomal protein, large, P2 | -0.0385007 |
| FLNB | filamin B, beta | -0.0381572 |
| RPL34 | ribosomal protein L34 | -0.0380558 |
| EMP3 | epithelial membrane protein 3 | -0.0376491 |
| PFN1 | profilin 1 | -0.0357448 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0346085 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0334513 |
| RPL26 | ribosomal protein L26 | -0.0331962 |
| TUBB | tubulin, beta class I | -0.0326509 |
| RPL9 | ribosomal protein L9 | -0.0311214 |
| LOXL3 | lysyl oxidase-like 3 | -0.030638 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0299665 |
| RPL37A | ribosomal protein L37a | -0.0299627 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0299585 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0297405 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0297266 |
| PRSS23 | protease, serine, 23 | -0.0296128 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0295175 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0294707 |
| PRDX2 | peroxiredoxin 2 | -0.0286603 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0285971 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0284805 |
| S100A9 | S100 calcium binding protein A9 | -0.0281558 |
| ACTN4 | actinin, alpha 4 | -0.0281208 |
| S100A10 | S100 calcium binding protein A10 | -0.0279704 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.027969 |
| RPL31 | ribosomal protein L31 | -0.0279197 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0275631 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0275416 |
| RACK1 | receptor for activated C kinase 1 | -0.0275248 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.027008 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0268072 |
| TPI1 | triosephosphate isomerase 1 | -0.026683 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0265723 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0260189 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0258958 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0258658 |
| RPS11 | ribosomal protein S11 | -0.0257339 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0255939 |
| RPL12 | ribosomal protein L12 | -0.025311 |
| DIAPH3 | diaphanous-related formin 3 | -0.02514 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0248173 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0247676 |
| RPS21 | ribosomal protein S21 | -0.0247597 |
| FHIT | fragile histidine triad | -0.0246594 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.023882 |
| RPLP0 | ribosomal protein, large, P0 | -0.0238143 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0237905 |
| BSG | basigin (Ok blood group) | -0.0236233 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0235707 |
| RPL8 | ribosomal protein L8 | -0.023445 |
| RPL27A | ribosomal protein L27a | -0.023426 |
| RPS13 | ribosomal protein S13 | -0.0233975 |
| RPL36 | ribosomal protein L36 | -0.0232998 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0232322 |
| CNTLN | centlein, centrosomal protein | -0.0231916 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0230152 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0230074 |
| RPL27 | ribosomal protein L27 | -0.0229184 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.022769 |
| RPL3 | ribosomal protein L3 | -0.0226506 |
| ATF4 | activating transcription factor 4 | -0.0224379 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0223956 |
| RPS14 | ribosomal protein S14 | -0.0223108 |
| GNAS | GNAS complex locus | -0.0220342 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0220097 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.021657 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0215828 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0214165 |
| RPS29 | ribosomal protein S29 | -0.021172 |
| NRF1 | nuclear respiratory factor 1 | -0.0211627 |
