| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.155935 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.136484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125605 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.112782 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.111076 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.105554 |
| ADM | adrenomedullin | 0.0985437 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0978839 |
| HDAC9 | histone deacetylase 9 | 0.0841034 |
| OGA | O-GlcNAcase | 0.0791251 |
| AHNAK | AHNAK nucleoprotein | 0.0781569 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0763381 |
| VCAN | versican | 0.0744973 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0723119 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0720034 |
| STC1 | stanniocalcin 1 | 0.0701582 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0693557 |
| GLIS3 | GLIS family zinc finger 3 | 0.0688687 |
| CANX | calnexin | 0.06699 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0610326 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0607659 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0591935 |
| HMGA2 | high mobility group AT-hook 2 | 0.0590287 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0566856 |
| LDHA | lactate dehydrogenase A | 0.0562252 |
| KYNU | kynureninase | 0.0546804 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.054417 |
| SFTPA2 | surfactant protein A2 | 0.0538679 |
| SMYD3 | SET and MYND domain containing 3 | 0.0533115 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0531774 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0518926 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0501844 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0462592 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0456266 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0450504 |
| HLA-E | major histocompatibility complex, class I, E | 0.0448393 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0443332 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0442886 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0441713 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.040159 |
| PHF3 | PHD finger protein 3 | 0.0395231 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0386087 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0382895 |
| SERINC1 | serine incorporator 1 | 0.0377953 |
| CCDC47 | coiled-coil domain containing 47 | 0.0376757 |
| GPC6 | glypican 6 | 0.0375474 |
| COL6A3 | collagen, type VI, alpha 3 | 0.036652 |
| RPL14 | ribosomal protein L14 | 0.0363188 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0360157 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0352353 |
| PGK1 | phosphoglycerate kinase 1 | 0.0349701 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0348997 |
| INTS6 | integrator complex subunit 6 | 0.0348309 |
| BPTF | bromodomain PHD finger transcription factor | 0.0338559 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0336304 |
| SDC4 | syndecan 4 | 0.0332241 |
| SQSTM1 | sequestosome 1 | 0.0328218 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0317642 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0315154 |
| PRELID2 | PRELI domain containing 2 | 0.0310564 |
| TXNIP | thioredoxin interacting protein | 0.0305851 |
| INHBA | inhibin, beta A | 0.03054 |
| ANLN | anillin, actin binding protein | 0.0303589 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0294836 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0287325 |
| ARRDC3 | arrestin domain containing 3 | 0.0286367 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0284074 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0283253 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0282874 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0282386 |
| YEATS2 | YEATS domain containing 2 | 0.0278143 |
| RPS3 | ribosomal protein S3 | 0.0277828 |
| CDK13 | cyclin-dependent kinase 13 | 0.0276665 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0276335 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0276281 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.027123 |
| YTHDC1 | YTH domain containing 1 | 0.0270141 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0269962 |
| FNIP1 | folliculin interacting protein 1 | 0.0268965 |
| APP | amyloid beta (A4) precursor protein | 0.0267651 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0265972 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0265962 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0262947 |
| SET | SET nuclear proto-oncogene | 0.0261121 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0260247 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0260231 |
| ARFGEF3 | ARFGEF family member 3 | 0.0259718 |
| JMJD1C | jumonji domain containing 1C | 0.0258094 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0253813 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0253684 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.025318 |
| SDCBP | syndecan binding protein (syntenin) | 0.0253109 |
| GDF15 | growth differentiation factor 15 | 0.025264 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0252623 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.025046 |
| CEP170 | centrosomal protein 170kDa | 0.0250307 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0246611 |
| CEP250 | centrosomal protein 250kDa | 0.0245499 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0245214 |
| EGFR | epidermal growth factor receptor | 0.0244856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.239107 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183766 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.136406 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.130475 |
| TMSB10 | thymosin beta 10 | -0.106855 |
| VCL | vinculin | -0.10327 |
| FTL | ferritin, light polypeptide | -0.10109 |
| EGR1 | early growth response 1 | -0.0753144 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0726065 |
| C3 | complement component 3 | -0.0591587 |
| TPM4 | tropomyosin 4 | -0.0583221 |
| FN1 | fibronectin 1 | -0.0574156 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0560791 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0546117 |
| RTN4 | reticulon 4 | -0.0538075 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0531752 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0521347 |
| RPL35A | ribosomal protein L35a | -0.0509222 |
| ACTG1 | actin gamma 1 | -0.0471657 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.046432 |
| TPM1 | tropomyosin 1 (alpha) | -0.0459955 |
| CTSD | cathepsin D | -0.0453243 |
| MSN | moesin | -0.0444036 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0443654 |
| PALLD | palladin, cytoskeletal associated protein | -0.0436073 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427802 |
| POTEF | POTE ankyrin domain family, member F | -0.042066 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0414533 |
| RPS19 | ribosomal protein S19 | -0.0412501 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0409887 |
| NAV1 | neuron navigator 1 | -0.0403807 |
| COL1A1 | collagen, type I, alpha 1 | -0.0386926 |
| CADM1 | cell adhesion molecule 1 | -0.0377271 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0375344 |
| EXT1 | exostosin glycosyltransferase 1 | -0.037116 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0364733 |
| TNNC1 | troponin C type 1 (slow) | -0.035927 |
| CALD1 | caldesmon 1 | -0.03563 |
| PLPP6 | phospholipid phosphatase 6 | -0.0354836 |
| B2M | beta-2-microglobulin | -0.0348465 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0335276 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0333901 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329972 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.032927 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0325084 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0321755 |
| IER3 | immediate early response 3 | -0.0320983 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0314348 |
| RPL28 | ribosomal protein L28 | -0.0308881 |
| HLA-B | major histocompatibility complex, class I, B | -0.0305888 |
| FOSL1 | FOS-like antigen 1 | -0.0305099 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0304063 |
| PKM | pyruvate kinase, muscle | -0.030395 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0300699 |
| THBS1 | thrombospondin 1 | -0.030044 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0291528 |
| QKI | QKI, KH domain containing, RNA binding | -0.0291051 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0282847 |
| RIGI | RNA sensor RIG-I | -0.028277 |
| RPS6 | ribosomal protein S6 | -0.0276972 |
| TAPBP | TAP binding protein (tapasin) | -0.0276881 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0276642 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.027412 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0273079 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0271975 |
| PFN1 | profilin 1 | -0.0270617 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0265681 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0262327 |
| CCNL1 | cyclin L1 | -0.0261376 |
| MYOF | myoferlin | -0.0257809 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0255816 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0255773 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254702 |
| CLIC4 | chloride intracellular channel 4 | -0.0254066 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0252989 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0251437 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0241578 |
| ACTN1 | actinin, alpha 1 | -0.0236687 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0235887 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0230915 |
| MX1 | MX dynamin-like GTPase 1 | -0.0228345 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.022796 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0227813 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0226353 |
| BRD4 | bromodomain containing 4 | -0.0223975 |
| RPS23 | ribosomal protein S23 | -0.0223238 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0222256 |
| HMGB1 | high mobility group box 1 | -0.0221653 |
| RRBP1 | ribosome binding protein 1 | -0.0221491 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0217344 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0217006 |
| LIMA1 | LIM domain and actin binding 1 | -0.0215689 |
| HMGA1 | high mobility group AT-hook 1 | -0.0215111 |
| TBK1 | TANK-binding kinase 1 | -0.0209921 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0206265 |
| CST3 | cystatin C | -0.0205555 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.020531 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0205016 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0204999 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0203979 |
