| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.181295 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0694781 |
| GLIS3 | GLIS family zinc finger 3 | 0.0684322 |
| KYNU | kynureninase | 0.0646887 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0535801 |
| ERBIN | erbb2 interacting protein | 0.0513534 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0481732 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0420737 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0409801 |
| FMNL2 | formin-like 2 | 0.0394902 |
| DST | dystonin | 0.0394883 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0393727 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0387218 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0378223 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0373722 |
| INTS6 | integrator complex subunit 6 | 0.0365073 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0354089 |
| FAT1 | FAT atypical cadherin 1 | 0.035354 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.03473 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0346424 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0341112 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0340896 |
| CD44 | CD44 molecule (Indian blood group) | 0.0335242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0334269 |
| ZNF638 | zinc finger protein 638 | 0.03241 |
| WWOX | WW domain containing oxidoreductase | 0.0323651 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0323214 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0316987 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0312821 |
| FAM20C | family with sequence similarity 20, member C | 0.0312139 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308637 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0305207 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0301516 |
| RRM2 | ribonucleotide reductase M2 | 0.0301337 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0292292 |
| RAD51B | RAD51 paralog B | 0.0292154 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0288466 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0288116 |
| MYOF | myoferlin | 0.0285424 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0282902 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0282506 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.027701 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0275281 |
| INHBA | inhibin, beta A | 0.0273311 |
| UTRN | utrophin | 0.0271913 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0270761 |
| MKI67 | marker of proliferation Ki-67 | 0.0267524 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0265977 |
| NAV1 | neuron navigator 1 | 0.0265891 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0261653 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0261621 |
| FUS | FUS RNA binding protein | 0.0257614 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0257024 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0256026 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0253798 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.02525 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0248523 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0248367 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0244935 |
| FHIT | fragile histidine triad | 0.0244811 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0238829 |
| TBC1D5 | TBC1 domain family, member 5 | 0.023791 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0237031 |
| HDAC9 | histone deacetylase 9 | 0.023524 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0233369 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0232368 |
| RAB31 | RAB31, member RAS oncogene family | 0.0232026 |
| MED13L | mediator complex subunit 13-like | 0.0231641 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0229802 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02294 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0228204 |
| PTK2 | protein tyrosine kinase 2 | 0.0227539 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0227373 |
| SPIDR | scaffolding protein involved in DNA repair | 0.02268 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0225114 |
| NRXN3 | neurexin 3 | 0.0224757 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0222636 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.022123 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0218039 |
| BPTF | bromodomain PHD finger transcription factor | 0.0216931 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0215552 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0214951 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0214845 |
| RPL7 | ribosomal protein L7 | 0.0213008 |
| JAK1 | Janus kinase 1 | 0.0212645 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0212228 |
| NUP153 | nucleoporin 153kDa | 0.0210678 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0209804 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0209186 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0207559 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0207503 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.020712 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0205851 |
| JPH2 | junctophilin 2 | 0.020542 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0203235 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.020279 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0200968 |
| CMIP | c-Maf inducing protein | 0.0200345 |
| PCM1 | pericentriolar material 1 | 0.0199774 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0199171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241028 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.207065 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.159673 |
| TMSB10 | thymosin beta 10 | -0.15314 |
| VIM | vimentin | -0.144517 |
| HLA-B | major histocompatibility complex, class I, B | -0.138961 |
| FN1 | fibronectin 1 | -0.138817 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109264 |
| SDC4 | syndecan 4 | -0.100156 |
| B2M | beta-2-microglobulin | -0.0964499 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0932003 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0831234 |
| UBC | ubiquitin C | -0.0812221 |
| COL1A2 | collagen, type I, alpha 2 | -0.0738767 |
| CALU | calumenin | -0.0724164 |
| MT2A | metallothionein 2A | -0.0681493 |
| LOX | lysyl oxidase | -0.067668 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0661672 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0644456 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0603099 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0587534 |
| PGK1 | phosphoglycerate kinase 1 | -0.0580517 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0570678 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0551212 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0529717 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0503539 |
| HLA-C | major histocompatibility complex, class I, C | -0.0500507 |
| HLA-A | major histocompatibility complex, class I, A | -0.0492536 |
| KAZN | kazrin, periplakin interacting protein | -0.0484018 |
| ENO1 | enolase 1, (alpha) | -0.0478984 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0478195 |
| POTEF | POTE ankyrin domain family, member F | -0.0455864 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0455113 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0449576 |
| ZNF395 | zinc finger protein 395 | -0.0448144 |
| TPM4 | tropomyosin 4 | -0.044199 |
| PTMA | prothymosin, alpha | -0.0427078 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0417601 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406122 |
| CALR | calreticulin | -0.0402785 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0363057 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0361559 |
| FAM13A | family with sequence similarity 13, member A | -0.035048 |
| LMNA | lamin A/C | -0.034863 |
| GOLGA4 | golgin A4 | -0.0342949 |
| S100A6 | S100 calcium binding protein A6 | -0.0335886 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0328856 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0321694 |
| TMSB4X | thymosin beta 4, X-linked | -0.0319751 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0315443 |
| FRMD6 | FERM domain containing 6 | -0.0312065 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0310893 |
| CDH13 | cadherin 13 | -0.0306014 |
| CCNI | cyclin I | -0.0305068 |
| S100A10 | S100 calcium binding protein A10 | -0.030102 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0298117 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0296796 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296294 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0291223 |
| IL6 | interleukin 6 | -0.02873 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0285916 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281812 |
| TMEM165 | transmembrane protein 165 | -0.0280923 |
| TNS3 | tensin 3 | -0.0280629 |
| MT1X | metallothionein 1X | -0.0279823 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0279644 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0279369 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0279272 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0278994 |
| RPS27A | ribosomal protein S27a | -0.0275896 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0273491 |
| FLNB | filamin B, beta | -0.027206 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0269931 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0269236 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.026885 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.026801 |
| LAMB1 | laminin, beta 1 | -0.0265724 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0262367 |
| MMP12 | matrix metallopeptidase 12 | -0.0260869 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0250835 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.024892 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0247714 |
| CALD1 | caldesmon 1 | -0.0243312 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0241868 |
| FAM3C | family with sequence similarity 3, member C | -0.0235754 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0235752 |
| LDHA | lactate dehydrogenase A | -0.0235427 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0235322 |
| CA12 | carbonic anhydrase XII | -0.0234901 |
| NUCB2 | nucleobindin 2 | -0.0231273 |
| USP47 | ubiquitin specific peptidase 47 | -0.0229214 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0229112 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0228196 |
| ANXA5 | annexin A5 | -0.0226792 |
| CDK7 | cyclin-dependent kinase 7 | -0.0225387 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0224079 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0223889 |
| MAP4 | microtubule-associated protein 4 | -0.0223465 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0222007 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0221895 |
