Dengue Shock Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth. (Human Disease Ontology, DOID_0050125)
External Link https://www.disgenet.org/browser/0/1/0/C0376300
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Genes

18 genes associated with the disease Dengue Shock Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
CLEC5A C-type lectin domain family 5, member A
CMA1 chymase 1, mast cell
HLA-A major histocompatibility complex, class I, A
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
MICB MHC class I polypeptide-related sequence B
PLCB4 phospholipase C, beta 4
PLCE1 phospholipase C, epsilon 1
PLG plasminogen
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RP1 retinitis pigmentosa 1 (autosomal dominant)
TNF tumor necrosis factor
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VEGFA vascular endothelial growth factor A