Dental Caries Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification. (Experimental Factor Ontology, EFO_0003819)
Similar Terms
Downloads & Tools

Genes

2 genes associated with the trait Dental Caries in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
MTMR4 myotubularin related protein 4 0.310838
MPPED2 metallophosphoesterase domain containing 2 0.310838