Denys-Drash Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An autosomal dominant disease that is characterized by the association of diffuse mesangial sclerosis (DMS), male pseudohermaphroditism with a 46,XY karyotype, and nephroblastoma that derives_from an abnormality in the WT1 gene (Wilms' tumor suppressor gene). (Human Disease Ontology, DOID_3764)
External Link https://www.disgenet.org/browser/0/1/0/C0950121
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Genes

14 genes associated with the disease Denys-Drash Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
AFP alpha-fetoprotein
EGF epidermal growth factor
EGFR epidermal growth factor receptor
FN1 fibronectin 1
GRM5 glutamate receptor, metabotropic 5
NR5A1 nuclear receptor subfamily 5, group A, member 1
PAX2 paired box 2
PDGFA platelet-derived growth factor alpha polypeptide
PKD2 polycystic kidney disease 2 (autosomal dominant)
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1