Dermatomyositis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction.|A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) (Experimental Factor Ontology, EFO_0000398)
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Genes

631 genes co-occuring with the disease Dermatomyositis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
IFIH1 interferon induced with helicase C domain 1 3.797
TRIM33 tripartite motif containing 33 3.627
MORC3 MORC family CW-type zinc finger 3 3.624
CKM creatine kinase, muscle 3.285
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 3.284
CKMT1B creatine kinase, mitochondrial 1B 3.283
CKB creatine kinase, brain 3.283
TRIM21 tripartite motif containing 21 3.156
EXOSC10 exosome component 10 3.092
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.897
TRIM24 tripartite motif containing 24 2.822
NT5C1A 5'-nucleotidase, cytosolic IA 2.798
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 2.764
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.714
CD4 CD4 molecule 2.697
SAE1 SUMO1 activating enzyme subunit 1 2.673
HARS1 histidyl-tRNA synthetase 1 2.662
CRP C-reactive protein, pentraxin-related 2.655
CD8A CD8a molecule 2.636
TNF tumor necrosis factor 2.635
IFNA1 interferon, alpha 1 2.577
MX1 MX dynamin-like GTPase 1 2.542
RO60 Ro60, Y RNA binding protein 2.533
CHD3 chromodomain helicase DNA binding protein 3 2.515
IFNG interferon, gamma 2.515
MUC1 mucin 1, cell surface associated 2.509
TARS3 threonyl-tRNA synthetase 3 2.488
CHD4 chromodomain helicase DNA binding protein 4 2.482
IL6 interleukin 6 2.478
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.45
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.442
TARS1 threonyl-tRNA synthetase 1 2.431
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.374
IL1B interleukin 1, beta 2.373
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.329
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.326
IFNB1 interferon, beta 1, fibroblast 2.318
IL17A interleukin 17A 2.315
CXCL10 chemokine (C-X-C motif) ligand 10 2.272
AARS1 alanyl-tRNA synthetase 1 2.267
EXOSC9 exosome component 9 2.263
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.255
AARS2 alanyl-tRNA synthetase 2, mitochondrial 2.246
IL1A interleukin 1, alpha 2.245
PRTN3 proteinase 3 2.24
IL10 interleukin 10 2.228
SSB Sjogren syndrome antigen B (autoantigen La) 2.225
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 2.205
IL18 interleukin 18 2.193
CENPB centromere protein B, 80kDa 2.187
MB myoglobin 2.182
ISG15 ISG15 ubiquitin-like modifier 2.169
IL4 interleukin 4 2.159
PLEKHM3 pleckstrin homology domain containing, family M, member 3 2.156
IL2 interleukin 2 2.154
TLR7 toll-like receptor 7 2.137
DYSF dysferlin 2.125
SFTPD surfactant protein D 2.108
IARS1 isoleucyl-tRNA synthetase 1 2.084
IFI44L interferon-induced protein 44-like 2.078
CXCR3 chemokine (C-X-C motif) receptor 3 2.066
TGFB1 transforming growth factor, beta 1 2.062
CD19 CD19 molecule 2.055
CD68 CD68 molecule 2.043
JAK1 Janus kinase 1 2.035
TLR9 toll-like receptor 9 2.027
CXCR5 chemokine (C-X-C motif) receptor 5 2.012
CXCL8 chemokine (C-X-C motif) ligand 8 1.998
C3 complement component 3 1.995
CCL2 chemokine (C-C motif) ligand 2 1.993
IFNK interferon, kappa 1.992
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.973
MPO myeloperoxidase 1.972
ALB albumin 1.969
IFNA2 interferon, alpha 2 1.969
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.966
STAT1 signal transducer and activator of transcription 1, 91kDa 1.957
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.949
CXCL9 chemokine (C-X-C motif) ligand 9 1.948
WDFY4 WDFY family member 4 1.948
TYK2 tyrosine kinase 2 1.944
STAT4 signal transducer and activator of transcription 4 1.937
FOXP3 forkhead box P3 1.936
IL13 interleukin 13 1.928
MYH14 myosin, heavy chain 14, non-muscle 1.919
RSAD2 radical S-adenosyl methionine domain containing 2 1.918
NCAM1 neural cell adhesion molecule 1 1.909
PRF1 perforin 1 (pore forming protein) 1.907
CLEC4C C-type lectin domain family 4, member C 1.896
IFI27 interferon, alpha-inducible protein 27 1.895
CD28 CD28 molecule 1.887
IL31 interleukin 31 1.886
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.879
IRF5 interferon regulatory factor 5 1.879
ICAM1 intercellular adhesion molecule 1 1.873
DMD dystrophin 1.871
PLCL1 phospholipase C-like 1 1.871
PSIP1 PC4 and SFRS1 interacting protein 1 1.865
IRF7 interferon regulatory factor 7 1.86
TLR3 toll-like receptor 3 1.859
IFNA17 interferon, alpha 17 1.845
SUMO1 small ubiquitin-like modifier 1 1.844
IFI44 interferon-induced protein 44 1.84
ICOS inducible T-cell co-stimulator 1.836
CD40LG CD40 ligand 1.831
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.829
IL15 interleukin 15 1.828
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.816
VWF von Willebrand factor 1.81
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.81
NLRC4 NLR family, CARD domain containing 4 1.808
TLR4 toll-like receptor 4 1.802
IL22 interleukin 22 1.801
IFNA4 interferon, alpha 4 1.8
C4A complement component 4A (Rodgers blood group) 1.797
IFNA5 interferon, alpha 5 1.782
IFNA10 interferon, alpha 10 1.781
CD163 CD163 molecule 1.78
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.78
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.779
IFNA7 interferon, alpha 7 1.776
IFNA8 interferon, alpha 8 1.775
IFNA6 interferon, alpha 6 1.774
IFNA21 interferon, alpha 21 1.772
IFNA16 interferon, alpha 16 1.77
IFNA14 interferon, alpha 14 1.769
CD40 CD40 molecule, TNF receptor superfamily member 5 1.769
BLK BLK proto-oncogene, Src family tyrosine kinase 1.768
POMC proopiomelanocortin 1.767
LGALS9 lectin, galactoside-binding, soluble, 9 1.766
LGALS9B lectin, galactoside-binding, soluble, 9B 1.757
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.756
LGALS9C lectin, galactoside-binding, soluble, 9C 1.755
LY6E lymphocyte antigen 6 complex, locus E 1.755
IFNA13 interferon, alpha 13 1.751
VCAM1 vascular cell adhesion molecule 1 1.749
CCR6 chemokine (C-C motif) receptor 6 1.74
JAK3 Janus kinase 3 1.738
CD80 CD80 molecule 1.733
HLA-B major histocompatibility complex, class I, B 1.731
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.731
FBL fibrillarin 1.729
MUSK muscle, skeletal, receptor tyrosine kinase 1.726
CD274 CD274 molecule 1.723
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.722
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.719
CCRL2 chemokine (C-C motif) receptor-like 2 1.714
IL5 interleukin 5 1.714
CD86 CD86 molecule 1.711
IFI6 interferon, alpha-inducible protein 6 1.706
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.704
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.702
NARS1 asparaginyl-tRNA synthetase 1 1.701
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 1.692
COL17A1 collagen, type XVII, alpha 1 1.689
IL3RA interleukin 3 receptor, alpha (low affinity) 1.688
CXCL11 chemokine (C-X-C motif) ligand 11 1.688
JAK2 Janus kinase 2 1.686
CD27 CD27 molecule 1.686
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.685
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.679
YARS1 tyrosyl-tRNA synthetase 1 1.675
LCE2D late cornified envelope 2D 1.664
IRF3 interferon regulatory factor 3 1.66
CAMP cathelicidin antimicrobial peptide 1.659
IFNE interferon, epsilon 1.659
CXCL13 chemokine (C-X-C motif) ligand 13 1.656
PDCD1 programmed cell death 1 1.653
CAPN3 calpain 3, (p94) 1.65
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 1.65
ACE angiotensin I converting enzyme 1.648
IL7 interleukin 7 1.646
CCL19 chemokine (C-C motif) ligand 19 1.646
CCL3 chemokine (C-C motif) ligand 3 1.644
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.643
CCR7 chemokine (C-C motif) receptor 7 1.642
PTPRC protein tyrosine phosphatase, receptor type, C 1.641
SAMHD1 SAM domain and HD domain 1 1.631
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.629
INS insulin 1.629
APOH apolipoprotein H (beta-2-glycoprotein I) 1.629
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.627
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.625
CGAS cyclic GMP-AMP synthase 1.61
NLRP3 NLR family, pyrin domain containing 3 1.608
STING1 stimulator of interferon response cGAMP interactor 1 1.603
CCAR1 cell division cycle and apoptosis regulator 1 1.602
MYOD1 myogenic differentiation 1 1.602
MYOG myogenin (myogenic factor 4) 1.601
MSTN myostatin 1.599
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.596
MAVS mitochondrial antiviral signaling protein 1.592
STAT2 signal transducer and activator of transcription 2, 113kDa 1.591
RNASEH2B ribonuclease H2, subunit B 1.591
CD38 CD38 molecule 1.581
CCL21 chemokine (C-C motif) ligand 21 1.58
DNASE1L3 deoxyribonuclease I-like 3 1.579
CCL4 chemokine (C-C motif) ligand 4 1.575
OASL 2'-5'-oligoadenylate synthetase-like 1.565
IL1RN interleukin 1 receptor antagonist 1.564
TRAT1 T cell receptor associated transmembrane adaptor 1 1.562
TLR2 toll-like receptor 2 1.561
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.557
USP18 ubiquitin specific peptidase 18 1.554
IRF9 interferon regulatory factor 9 1.553
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.553
DST dystonin 1.553
ACE2 angiotensin I converting enzyme 2 1.553
TRIM28 tripartite motif containing 28 1.55
UBTF upstream binding transcription factor, RNA polymerase I 1.55
TLR8 toll-like receptor 8 1.546
SRP54 signal recognition particle 54kDa 1.543
TBX21 T-box 21 1.536
IFNL1 interferon, lambda 1 1.534
CCL5 chemokine (C-C motif) ligand 5 1.533
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.531
RNASEH2C ribonuclease H2, subunit C 1.53
CSF3 colony stimulating factor 3 (granulocyte) 1.526
PAX7 paired box 7 1.525
TMEM11 transmembrane protein 11 1.519
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.515
CD1C CD1c molecule 1.509
HLA-A major histocompatibility complex, class I, A 1.507
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.501
F3 coagulation factor III (thromboplastin, tissue factor) 1.5
BCL6 B-cell CLL/lymphoma 6 1.499
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.498
MGA MGA, MAX dimerization protein 1.497
FKRP fukutin related protein 1.497
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.493
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.491
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.486
PNMA2 paraneoplastic Ma antigen 2 1.485
TREX1 three prime repair exonuclease 1 1.482
RNASEH2A ribonuclease H2, subunit A 1.482
FAM167A family with sequence similarity 167, member A 1.478
PTH parathyroid hormone 1.475
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 1.475
IL2RA interleukin 2 receptor, alpha 1.472
PXDN peroxidasin 1.471
SPP1 secreted phosphoprotein 1 1.471
PXDNL peroxidasin-like 1.47
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.459
VCP valosin containing protein 1.459
OCA2 oculocutaneous albinism II 1.458
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.455
TPO thyroid peroxidase 1.453
TARDBP TAR DNA binding protein 1.45
C4B complement component 4B (Chido blood group) 1.449
IL33 interleukin 33 1.448
NPPB natriuretic peptide B 1.447
ANKRD55 ankyrin repeat domain 55 1.443
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.442
IL17F interleukin 17F 1.442
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.441
CXCR4 chemokine (C-X-C motif) receptor 4 1.441
MYD88 myeloid differentiation primary response 88 1.441
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.439
CCL8 chemokine (C-C motif) ligand 8 1.436
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.432
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.431
TOR1A torsin family 1, member A (torsin A) 1.43
TNNI3 troponin I type 3 (cardiac) 1.429
IRF8 interferon regulatory factor 8 1.429
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.429
IFI16 interferon, gamma-inducible protein 16 1.428
TBK1 TANK-binding kinase 1 1.426
IL21R interleukin 21 receptor 1.426
MX2 MX dynamin-like GTPase 2 1.425
TTN titin 1.423
BANK1 B-cell scaffold protein with ankyrin repeats 1 1.423
IL31RA interleukin 31 receptor A 1.422
LOC102723996 ICOS ligand 1.422
CCL20 chemokine (C-C motif) ligand 20 1.418
GBP1 guanylate binding protein 1, interferon-inducible 1.418
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.417
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.416
DSG1 desmoglein 1 1.415
SNRPC small nuclear ribonucleoprotein polypeptide C 1.414
CD180 CD180 molecule 1.414
CENPA centromere protein A 1.413
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.412
CCL11 chemokine (C-C motif) ligand 11 1.412
FASLG Fas ligand (TNF superfamily, member 6) 1.409
FN1 fibronectin 1 1.408
ANO5 anoctamin 5 1.404
LMNA lamin A/C 1.399
CD5 CD5 molecule 1.395
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.395
DSG3 desmoglein 3 1.393
F2 coagulation factor II (thrombin) 1.393
RYR1 ryanodine receptor 1 (skeletal) 1.392
SRP72 signal recognition particle 72kDa 1.391
TP53 tumor protein p53 1.386
S100A9 S100 calcium binding protein A9 1.385
DPYSL5 dihydropyrimidinase-like 5 1.385
B3GAT1 beta-1,3-glucuronyltransferase 1 1.381
IL9 interleukin 9 1.381
HLA-C major histocompatibility complex, class I, C 1.378
CD69 CD69 molecule 1.376
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.374
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.374
CCN2 cellular communication network factor 2 1.373
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 1.371
ANGPTL2 angiopoietin-like 2 1.371
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.37
SELE selectin E 1.369
AMPH amphiphysin 1.369
PCNA proliferating cell nuclear antigen 1.368
DNAH8 dynein, axonemal, heavy chain 8 1.366
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.365
THBD thrombomodulin 1.363
SDC1 syndecan 1 1.363
CD1D CD1d molecule 1.362
MBL2 mannose-binding lectin (protein C) 2, soluble 1.362
AIRE autoimmune regulator 1.361
PUF60 poly-U binding splicing factor 60KDa 1.359
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.356
PECAM1 platelet/endothelial cell adhesion molecule 1 1.356
CD276 CD276 molecule 1.352
CD34 CD34 molecule 1.352
B2M beta-2-microglobulin 1.351
CD1B CD1b molecule 1.349
RUVBL1 RuvB-like AAA ATPase 1 1.349
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.348
HMGB1 high mobility group box 1 1.346
MRC1 mannose receptor, C type 1 1.344
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.343
TG thyroglobulin 1.342
AMPD1 adenosine monophosphate deaminase 1 1.341
CD1E CD1e molecule 1.34
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.339
RNPC3 RNA-binding region (RNP1, RRM) containing 3 1.337
LAMP3 lysosomal-associated membrane protein 3 1.333
MYOT myotilin 1.332
BCL2 B-cell CLL/lymphoma 2 1.331
MEFV Mediterranean fever 1.331
CD1A CD1a molecule 1.329
MMP9 matrix metallopeptidase 9 1.327
FST follistatin 1.322
IL3 interleukin 3 1.321
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.321
ADCY4 adenylate cyclase 4 1.319
ADAR adenosine deaminase, RNA-specific 1.318
ADA2 adenosine deaminase 2 1.315
CD59 CD59 molecule, complement regulatory protein 1.315
CD83 CD83 molecule 1.315
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.314
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.313
EPSTI1 epithelial stromal interaction 1 (breast) 1.312
UTRN utrophin 1.311
MMP3 matrix metallopeptidase 3 1.308
MOG myelin oligodendrocyte glycoprotein 1.305
STAT5B signal transducer and activator of transcription 5B 1.301
S100A12 S100 calcium binding protein A12 1.299
CCR2 chemokine (C-C motif) receptor 2 1.298
SH2D1A SH2 domain containing 1A 1.292
IFI35 interferon-induced protein 35 1.291
ELANE elastase, neutrophil expressed 1.29
ACTA1 actin, alpha 1, skeletal muscle 1.289
SELL selectin L 1.285
BIN1 bridging integrator 1 1.284
SNRPA small nuclear ribonucleoprotein polypeptide A 1.282
IL7R interleukin 7 receptor 1.281
FGF7 fibroblast growth factor 7 1.28
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.279
LCE1B late cornified envelope 1B 1.279
FBXO32 F-box protein 32 1.273
HAVCR2 hepatitis A virus cellular receptor 2 1.273
IRAK1 interleukin-1 receptor-associated kinase 1 1.272
CD52 CD52 molecule 1.272
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.271
FGF2 fibroblast growth factor 2 (basic) 1.269
ACTB actin, beta 1.267
AIM2 absent in melanoma 2 1.266
CCL17 chemokine (C-C motif) ligand 17 1.266
RPP38 ribonuclease P/MRP 38kDa subunit 1.264
LGI1 leucine-rich, glioma inactivated 1 1.256
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.256
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.255
ICOSLG inducible T-cell co-stimulator ligand 1.254
IRF1 interferon regulatory factor 1 1.254
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.254
IL6R interleukin 6 receptor 1.252
CAV3 caveolin 3 1.251
DGCR6 DiGeorge syndrome critical region gene 6 1.251
PRDM1 PR domain containing 1, with ZNF domain 1.251
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 1.249
PADI4 peptidyl arginine deiminase, type IV 1.248
IRF4 interferon regulatory factor 4 1.248
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.247
MYH2 myosin, heavy chain 2, skeletal muscle, adult 1.247
FGF3 fibroblast growth factor 3 1.246
SQSTM1 sequestosome 1 1.243
PF4 platelet factor 4 1.243
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.242
CXCL12 chemokine (C-X-C motif) ligand 12 1.24
FGF4 fibroblast growth factor 4 1.236
EDN1 endothelin 1 1.236
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.235
GATA3 GATA binding protein 3 1.235
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.234
IFITM1 interferon induced transmembrane protein 1 1.233
FGF18 fibroblast growth factor 18 1.232
RBBP4 retinoblastoma binding protein 4 1.232
FGF8 fibroblast growth factor 8 (androgen-induced) 1.23
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.229
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.229
IGF1 insulin-like growth factor 1 (somatomedin C) 1.227
PLSCR1 phospholipid scramblase 1 1.226
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.223
CD2 CD2 molecule 1.222
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.221
BTK Bruton agammaglobulinemia tyrosine kinase 1.221
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.22
FGF6 fibroblast growth factor 6 1.22
TRIM22 tripartite motif containing 22 1.22
UNC13D unc-13 homolog D (C. elegans) 1.219
DNASE1 deoxyribonuclease I 1.219
FGF5 fibroblast growth factor 5 1.219
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.218
FGF22 fibroblast growth factor 22 1.215
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.214
FGF16 fibroblast growth factor 16 1.213
FGF20 fibroblast growth factor 20 1.21
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.208
FGF17 fibroblast growth factor 17 1.208
SFTPC surfactant protein C 1.207
DGCR6L DiGeorge syndrome critical region gene 6-like 1.207
CTSG cathepsin G 1.206
FGF9 fibroblast growth factor 9 1.202
FGF10 fibroblast growth factor 10 1.199
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.197
ELN elastin 1.195
C5 complement component 5 1.194
C1R complement component 1, r subcomponent 1.194
RPP25 ribonuclease P/MRP 25kDa subunit 1.192
STAT5A signal transducer and activator of transcription 5A 1.19
SYK spleen tyrosine kinase 1.19
FLG2 filaggrin family member 2 1.19
LAMA2 laminin, alpha 2 1.189
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.189
GBP2 guanylate binding protein 2, interferon-inducible 1.187
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 1.187
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 1.186
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.186
CD22 CD22 molecule 1.185
CD79A CD79a molecule, immunoglobulin-associated alpha 1.185
ENO2 enolase 2 (gamma, neuronal) 1.185
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.184
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.182
IFNL2 interferon, lambda 2 1.18
AGRN agrin 1.179
MYF5 myogenic factor 5 1.177
CD244 CD244 molecule, natural killer cell receptor 2B4 1.176
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.173
KRT19 keratin 19, type I 1.173
IL21 interleukin 21 1.171
FLG filaggrin 1.17
FAS Fas cell surface death receptor 1.17
POSTN periostin, osteoblast specific factor 1.167
PARP9 poly (ADP-ribose) polymerase family, member 9 1.167
SRP19 signal recognition particle 19kDa 1.167
IRAK4 interleukin-1 receptor-associated kinase 4 1.166
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.165
PDCD1LG2 programmed cell death 1 ligand 2 1.164
PPARG peroxisome proliferator-activated receptor gamma 1.163
IFNGR1 interferon gamma receptor 1 1.163
TGM2 transglutaminase 2 1.163
AVP arginine vasopressin 1.161
SMAD2 SMAD family member 2 1.159
NELFCD negative elongation factor complex member C/D 1.159
CD24 CD24 molecule 1.157
MGP matrix Gla protein 1.156
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.155
HLA-DRA major histocompatibility complex, class II, DR alpha 1.149
FSTL1 follistatin-like 1 1.147
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.146
SOCS1 suppressor of cytokine signaling 1 1.145
LEP leptin 1.145
HP haptoglobin 1.145
RBBP7 retinoblastoma binding protein 7 1.141
IL23R interleukin 23 receptor 1.139
CD226 CD226 molecule 1.135
TPMT thiopurine S-methyltransferase 1.134
CHD1 chromodomain helicase DNA binding protein 1 1.134
TPM4 tropomyosin 4 1.134
NOD2 nucleotide-binding oligomerization domain containing 2 1.133
MMP1 matrix metallopeptidase 1 1.132
TFRC transferrin receptor 1.132
CSF1 colony stimulating factor 1 (macrophage) 1.131
BCR breakpoint cluster region 1.13
EGFR epidermal growth factor receptor 1.126
TOP1 topoisomerase (DNA) I 1.126
SOX1 SRY (sex determining region Y)-box 1 1.125
IL16 interleukin 16 1.125
GZMK granzyme K (granzyme 3; tryptase II) 1.125
MME membrane metallo-endopeptidase 1.123
FYCO1 FYVE and coiled-coil domain containing 1 1.123
CD44 CD44 molecule (Indian blood group) 1.123
CENPS centromere protein S 1.123
IL1R1 interleukin 1 receptor, type I 1.122
APP amyloid beta (A4) precursor protein 1.121
KRT80 keratin 80, type II 1.12
ISG20 interferon stimulated exonuclease gene 20kDa 1.118
EGF epidermal growth factor 1.116
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.115
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 1.114
XAF1 XIAP associated factor 1 1.112
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.112
CCR3 chemokine (C-C motif) receptor 3 1.111
H3C12 H3 clustered histone 12 1.11
SP100 SP100 nuclear antigen 1.11
MYF6 myogenic factor 6 (herculin) 1.109
C1S complement component 1, s subcomponent 1.108
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.106
TNNT2 troponin T type 2 (cardiac) 1.106
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.105
GDF15 growth differentiation factor 15 1.104
MBP myelin basic protein 1.103
AGBL2 ATP/GTP binding protein-like 2 1.102
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.102
CCL7 chemokine (C-C motif) ligand 7 1.101
DHFR2 dihydrofolate reductase 2 1.101
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.098
CNTNAP2 contactin associated protein-like 2 1.094
H3-4 H3.4 histone, cluster member 1.094
IDO1 indoleamine 2,3-dioxygenase 1 1.094
H3C13 H3 clustered histone 13 1.094
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.093
PYGM phosphorylase, glycogen, muscle 1.093
CIITA class II, major histocompatibility complex, transactivator 1.091
LAMP1 lysosomal-associated membrane protein 1 1.09
FLNC filamin C, gamma 1.089
H3-3B H3.3 histone B 1.088
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.088
H3-5 H3.5 histone 1.087
ENO1 enolase 1, (alpha) 1.087
TRIM38 tripartite motif containing 38 1.087
IL4R interleukin 4 receptor 1.086
BGLAP bone gamma-carboxyglutamate (gla) protein 1.086
JUN jun proto-oncogene 1.084
CAVIN1 caveolae associated protein 1 1.081
CD84 CD84 molecule 1.081
UBA1 ubiquitin-like modifier activating enzyme 1 1.08
RAG2 recombination activating gene 2 1.077
SAA1 serum amyloid A1 1.077
THBS1 thrombospondin 1 1.076
RC3H1 ring finger and CCCH-type domains 1 1.075
MMP7 matrix metallopeptidase 7 1.074
ADA adenosine deaminase 1.073
MAG myelin associated glycoprotein 1.073
LTF lactotransferrin 1.073
STXBP2 syntaxin binding protein 2 1.072
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.072
NEMP2 nuclear envelope integral membrane protein 2 1.071
TOP1MT topoisomerase (DNA) I, mitochondrial 1.071
CCL27 chemokine (C-C motif) ligand 27 1.07
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 1.068
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.066
CD70 CD70 molecule 1.066
IL18BP interleukin 18 binding protein 1.065
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.064
STX11 syntaxin 11 1.063
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.061
WARS1 tryptophanyl-tRNA synthetase 1 1.061
RETN resistin 1.061
KARS1 lysyl-tRNA synthetase 1 1.06
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.06
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.059
RETNLB resistin like beta 1.058
DCN decorin 1.058
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.057
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.056
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.055
LTA lymphotoxin alpha 1.053
ACP5 acid phosphatase 5, tartrate resistant 1.051
OSMR oncostatin M receptor 1.051
HSPA4 heat shock 70kDa protein 4 1.051
MORC1 MORC family CW-type zinc finger 1 1.049
EMD emerin 1.048
BICD2 bicaudal D homolog 2 (Drosophila) 1.048
IL26 interleukin 26 1.044
ERBB2 erb-b2 receptor tyrosine kinase 2 1.044
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.042
H2BC21 H2B clustered histone 21 1.042
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.042
LYST lysosomal trafficking regulator 1.04
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.037
SRP68 signal recognition particle 68kDa 1.036
OSM oncostatin M 1.036
ACTN3 actinin, alpha 3 (gene/pseudogene) 1.035
DHFR dihydrofolate reductase 1.034
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.033
CENPC centromere protein C 1.032
GNLY granulysin 1.032
NUP210 nucleoporin 210kDa 1.029
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.028
COL1A1 collagen, type I, alpha 1 1.027
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.026
TSLP thymic stromal lymphopoietin 1.026
HCLS1 hematopoietic cell-specific Lyn substrate 1 1.026
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.025
RAPSN receptor-associated protein of the synapse 1.025
IFITM2 interferon induced transmembrane protein 2 1.025
CCL22 chemokine (C-C motif) ligand 22 1.024
AICDA activation-induced cytidine deaminase 1.024
CTTN cortactin 1.023
IL17RA interleukin 17 receptor A 1.022
ADIPOQ adiponectin, C1Q and collagen domain containing 1.021
MYOM2 myomesin 2 1.02
IFNL3 interferon, lambda 3 1.02
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.02
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.019
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.019
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.017
CCR1 chemokine (C-C motif) receptor 1 1.017
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.014
RAG1 recombination activating gene 1 1.013
IL11 interleukin 11 1.013
NLRP1 NLR family, pyrin domain containing 1 1.013
RORC RAR-related orphan receptor C 1.011
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.011
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.011
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.009
ENG endoglin 1.008
C1QA complement component 1, q subcomponent, A chain 1.007
SLAMF1 signaling lymphocytic activation molecule family member 1 1.005
AREG amphiregulin 1.003
EPO erythropoietin 1.001