Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE1551 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1551
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Genes

600 genes differentially expressed during Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE1551 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 3.00461
MSL1 male-specific lethal 1 homolog (Drosophila) 2.70684
RC3H2 ring finger and CCCH-type domains 2 2.68696
RHOA ras homolog family member A 2.651
FBXO7 F-box protein 7 2.52233
GTF3A general transcription factor IIIA 2.40822
EIF4A3 eukaryotic translation initiation factor 4A3 2.37
TSTA3 tissue specific transplantation antigen P35B 2.33143
PRPF19 pre-mRNA processing factor 19 2.32561
DUSP14 dual specificity phosphatase 14 2.32519
CRYAB crystallin, alpha B 2.31067
XPO6 exportin 6 2.3074
MTCH1 mitochondrial carrier 1 2.28765
RPP30 ribonuclease P/MRP 30kDa subunit 2.26855
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 2.25858
TRIP12 thyroid hormone receptor interactor 12 2.24808
RER1 retention in endoplasmic reticulum sorting receptor 1 2.24416
ZNF207 zinc finger protein 207 2.18784
ETF1 eukaryotic translation termination factor 1 2.18465
PRR13 proline rich 13 2.1509
B2M beta-2-microglobulin 2.13658
C14ORF166 chromosome 14 open reading frame 166 2.13336
CHPT1 choline phosphotransferase 1 2.11317
TM9SF1 transmembrane 9 superfamily member 1 2.08858
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.08341
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 2.08292
KLHDC4 kelch domain containing 4 2.06721
SSH1 slingshot protein phosphatase 1 2.06499
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.06141
SUSD6 sushi domain containing 6 2.05906
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 2.0338
TRAPPC3 trafficking protein particle complex 3 2.01856
DFNB31 deafness, autosomal recessive 31 2.01226
SH3GLB1 SH3-domain GRB2-like endophilin B1 1.99127
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.98948
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 1.9842
INTS6 integrator complex subunit 6 1.97757
MORF4L2 mortality factor 4 like 2 1.96115
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.95738
TTC17 tetratricopeptide repeat domain 17 1.95339
NFE2L1 nuclear factor, erythroid 2-like 1 1.95161
REEP5 receptor accessory protein 5 1.93555
CTTNBP2NL CTTNBP2 N-terminal like 1.92618
C18ORF8 chromosome 18 open reading frame 8 1.92254
GRAMD4 GRAM domain containing 4 1.91885
MTDH metadherin 1.90701
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.90404
TERF2IP telomeric repeat binding factor 2, interacting protein 1.89621
SP100 SP100 nuclear antigen 1.89285
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.89132
ACLY ATP citrate lyase 1.88368
BCL7B B-cell CLL/lymphoma 7B 1.87802
CCDC92 coiled-coil domain containing 92 1.87472
PAPOLA poly(A) polymerase alpha 1.8709
PTPRK protein tyrosine phosphatase, receptor type, K 1.86915
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 1.84889
NFX1 nuclear transcription factor, X-box binding 1 1.8467
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 1.8459
PITPNB phosphatidylinositol transfer protein, beta 1.84556
SAT1 spermidine/spermine N1-acetyltransferase 1 1.84228
INTS5 integrator complex subunit 5 1.83983
OGFRL1 opioid growth factor receptor-like 1 1.83241
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 1.82905
CBY1 chibby homolog 1 (Drosophila) 1.82457
DMWD dystrophia myotonica, WD repeat containing 1.81502
NSUN3 NOP2/Sun domain family, member 3 1.81162
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.81115
CCND3 cyclin D3 1.81084
TMEM5 transmembrane protein 5 1.80927
SAR1B secretion associated, Ras related GTPase 1B 1.79642
TSPYL2 TSPY-like 2 1.79017
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.7858
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.785
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.78137
BLMH bleomycin hydrolase 1.77922
ODC1 ornithine decarboxylase 1 1.77658
GPR89B G protein-coupled receptor 89B 1.77484
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.75712
LRP10 low density lipoprotein receptor-related protein 10 1.75299
DYNLRB1 dynein, light chain, roadblock-type 1 1.7523
POMP proteasome maturation protein 1.75145
ORAI3 ORAI calcium release-activated calcium modulator 3 1.74901
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1.74015
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.735
CIAPIN1 cytokine induced apoptosis inhibitor 1 1.73207
JAK1 Janus kinase 1 1.72997
HSPB8 heat shock 22kDa protein 8 1.72811
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.71829
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.71279
WDR5B WD repeat domain 5B 1.70777
AAGAB alpha- and gamma-adaptin binding protein 1.69732
CDC37L1 cell division cycle 37-like 1 1.6943
BLVRA biliverdin reductase A 1.67694
RAN RAN, member RAS oncogene family 1.67575
EIF4A1 eukaryotic translation initiation factor 4A1 1.67541
HYAL2 hyaluronoglucosaminidase 2 1.67397
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 1.67074
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.66971
RPS14 ribosomal protein S14 1.66463
MYO1E myosin IE 1.65087
CST3 cystatin C 1.65033
SLC38A2 solute carrier family 38, member 2 1.65004
TMEM147 transmembrane protein 147 1.6473
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.64259
PHTF1 putative homeodomain transcription factor 1 1.64077
HMGN2 high mobility group nucleosomal binding domain 2 1.6404
C7ORF49 chromosome 7 open reading frame 49 1.63996
TCP1 t-complex 1 1.63845
PPAP2A phosphatidic acid phosphatase type 2A 1.63819
PCDHGA1 protocadherin gamma subfamily A, 1 1.63632
RNASEH2A ribonuclease H2, subunit A 1.63421
OSBPL10 oxysterol binding protein-like 10 1.6316
DOK2 docking protein 2, 56kDa 1.62517
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.62126
ADM adrenomedullin 1.61748
HSPH1 heat shock 105kDa/110kDa protein 1 1.61669
SRP72 signal recognition particle 72kDa 1.61529
WIPF2 WAS/WASL interacting protein family, member 2 1.61327
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.60364
PPME1 protein phosphatase methylesterase 1 1.60278
LMBR1L limb development membrane protein 1-like 1.60155
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 1.60097
KIAA1551 KIAA1551 1.59877
IFT57 intraflagellar transport 57 1.59844
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.59677
SEC24A SEC24 family member A 1.59399
NUP98 nucleoporin 98kDa 1.58619
CRTC3 CREB regulated transcription coactivator 3 1.58531
GEMIN8 gem (nuclear organelle) associated protein 8 1.57604
C19ORF66 chromosome 19 open reading frame 66 1.57371
CCNH cyclin H 1.57242
DUSP22 dual specificity phosphatase 22 1.57224
CFL1 cofilin 1 (non-muscle) 1.56485
TMX2 thioredoxin-related transmembrane protein 2 1.55889
KIF3B kinesin family member 3B 1.55529
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.55487
CTTN cortactin 1.55418
LRRC49 leucine rich repeat containing 49 1.55059
CNPY2 canopy FGF signaling regulator 2 1.55015
RBM15B RNA binding motif protein 15B 1.54839
PPA1 pyrophosphatase (inorganic) 1 1.54767
RPL41 ribosomal protein L41 1.54293
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 1.53844
WAC WW domain containing adaptor with coiled-coil 1.53816
HAUS7 HAUS augmin-like complex, subunit 7 1.53585
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.53437
EIF5B eukaryotic translation initiation factor 5B 1.53359
STX4 syntaxin 4 1.53308
MAP7D1 MAP7 domain containing 1 1.53306
HFE hemochromatosis 1.53172
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.52791
KIAA0556 KIAA0556 1.52776
UVRAG UV radiation resistance associated 1.52425
SLN sarcolipin 1.51916
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.51832
U2AF1 U2 small nuclear RNA auxiliary factor 1 1.51645
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.516
PITPNA phosphatidylinositol transfer protein, alpha 1.51576
ADPGK ADP-dependent glucokinase 1.50695
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.50662
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 1.50371
HSPB3 heat shock 27kDa protein 3 1.50286
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.5017
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.49509
TXNDC9 thioredoxin domain containing 9 1.49373
TRMT5 tRNA methyltransferase 5 1.48849
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.48816
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.4826
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.48257
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.48219
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 1.47315
GMEB2 glucocorticoid modulatory element binding protein 2 1.47172
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 1.47074
HSPB1 heat shock 27kDa protein 1 1.47064
LEPROTL1 leptin receptor overlapping transcript-like 1 1.47031
INPP1 inositol polyphosphate-1-phosphatase 1.47002
MRPL49 mitochondrial ribosomal protein L49 1.46992
PSEN1 presenilin 1 1.46988
UGP2 UDP-glucose pyrophosphorylase 2 1.46556
JTB jumping translocation breakpoint 1.45968
PAIP1 poly(A) binding protein interacting protein 1 1.45949
ATAD2B ATPase family, AAA domain containing 2B 1.45923
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.45898
ZNF764 zinc finger protein 764 1.4551
SF1 splicing factor 1 1.45484
CBFB core-binding factor, beta subunit 1.45467
TMEM97 transmembrane protein 97 1.45399
GDI1 GDP dissociation inhibitor 1 1.4528
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 1.45113
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.44776
PLEK pleckstrin 1.44495
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 1.44431
TRIM14 tripartite motif containing 14 1.44354
COG2 component of oligomeric golgi complex 2 1.44339
FAM222B family with sequence similarity 222, member B 1.44254
ZBED5 zinc finger, BED-type containing 5 1.4423
SRP19 signal recognition particle 19kDa 1.43942
SELT selenoprotein T 1.43794
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.43757
GIMAP5 GTPase, IMAP family member 5 1.43731
TEX10 testis expressed 10 1.43566
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.4329
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.4311
SAMHD1 SAM domain and HD domain 1 1.42844
MCRS1 microspherule protein 1 1.42228
HMGN4 high mobility group nucleosomal binding domain 4 1.42023
RHOG ras homolog family member G 1.41754
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.41683
ZBTB24 zinc finger and BTB domain containing 24 1.41337
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 1.4126
NUP85 nucleoporin 85kDa 1.41109
HARS histidyl-tRNA synthetase 1.41073
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.41067
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.40946
SMC6 structural maintenance of chromosomes 6 1.40785
NCSTN nicastrin 1.40778
RING1 ring finger protein 1 1.40693
KIAA0020 KIAA0020 1.40298
NUP88 nucleoporin 88kDa 1.40079
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.39786
PON2 paraoxonase 2 1.39477
GLTSCR1 glioma tumor suppressor candidate region gene 1 1.39453
C12ORF10 chromosome 12 open reading frame 10 1.39357
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.39007
CKAP5 cytoskeleton associated protein 5 1.38986
LYRM4 LYR motif containing 4 1.38451
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 1.38272
CD47 CD47 molecule 1.38265
ZMAT3 zinc finger, matrin-type 3 1.38264
TRIM33 tripartite motif containing 33 1.3821
TTC19 tetratricopeptide repeat domain 19 1.38143
EDA ectodysplasin A 1.38115
RPS27L ribosomal protein S27-like 1.38079
MED13L mediator complex subunit 13-like 1.38073
MTG1 mitochondrial ribosome-associated GTPase 1 1.3765
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 1.37627
HEXB hexosaminidase B (beta polypeptide) 1.37478
GPN1 GPN-loop GTPase 1 1.37374
MTF1 metal-regulatory transcription factor 1 1.3718
PLEKHO1 pleckstrin homology domain containing, family O member 1 1.37148
RNF139 ring finger protein 139 1.36845
RPL19 ribosomal protein L19 1.3681
TUBA1C tubulin, alpha 1c 1.36654
KLHL2 kelch-like family member 2 1.36557
C1ORF27 chromosome 1 open reading frame 27 1.3651
BIN3 bridging integrator 3 1.36448
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 1.36312
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 1.3631
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 1.36221
SNX11 sorting nexin 11 1.35981
HSPE1 heat shock 10kDa protein 1 1.35944
SRRD SRR1 domain containing 1.35921
PUS7 pseudouridylate synthase 7 (putative) 1.35858
RIT1 Ras-like without CAAX 1 1.35588
GPATCH8 G patch domain containing 8 1.35043
HINT1 histidine triad nucleotide binding protein 1 1.34922
EFHD2 EF-hand domain family, member D2 1.34863
PHC2 polyhomeotic homolog 2 (Drosophila) 1.3479
LYN LYN proto-oncogene, Src family tyrosine kinase 1.34287
ERGIC3 ERGIC and golgi 3 1.34173
TMEM40 transmembrane protein 40 1.3397
EXOSC4 exosome component 4 1.33699
EIF3B eukaryotic translation initiation factor 3, subunit B 1.33559
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.33519
HTRA2 HtrA serine peptidase 2 1.33466
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.3341
CORO1C coronin, actin binding protein, 1C 1.33379
TTLL7 tubulin tyrosine ligase-like family member 7 1.33131
PCDHGC3 protocadherin gamma subfamily C, 3 1.32729
C9ORF16 chromosome 9 open reading frame 16 1.32614
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1.32485
EMC7 ER membrane protein complex subunit 7 1.32438
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.32407
VAC14 Vac14 homolog (S. cerevisiae) 1.32239
NEK11 NIMA-related kinase 11 1.32094
HCRP1 hepatocellular carcinoma-related HCRP1 1.31983
GPATCH2 G patch domain containing 2 1.31809
ADRBK2 adrenergic, beta, receptor kinase 2 1.31531
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.31473
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.31446
GAK cyclin G associated kinase 1.31306
NFE2L3 nuclear factor, erythroid 2-like 3 1.31164
BBS9 Bardet-Biedl syndrome 9 1.31146
ZNF609 zinc finger protein 609 1.31136
ATN1 atrophin 1 1.30877
PRPF3 pre-mRNA processing factor 3 1.30799
ELP4 elongator acetyltransferase complex subunit 4 1.30781
HK1 hexokinase 1 1.30743
CHN2 chimerin 2 1.30674
HSPA4 heat shock 70kDa protein 4 1.30651
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 1.30463
HYOU1 hypoxia up-regulated 1 1.30438
SEC13 SEC13 homolog (S. cerevisiae) 1.30303
STRAP serine/threonine kinase receptor associated protein 1.30212
DCAF8 DDB1 and CUL4 associated factor 8 1.29864
DND1 DND microRNA-mediated repression inhibitor 1 1.29795
BABAM1 BRISC and BRCA1 A complex member 1 1.29762
HEATR1 HEAT repeat containing 1 1.2972
SDF2L1 stromal cell-derived factor 2-like 1 1.29464
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.29319

decreased expression

Symbol Name Standardized Value
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.24357
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -3.23304
QARS glutaminyl-tRNA synthetase -3.20026
CKM creatine kinase, muscle -3.18264
VDAC3 voltage-dependent anion channel 3 -2.98483
EIF3L eukaryotic translation initiation factor 3, subunit L -2.9376
NNT nicotinamide nucleotide transhydrogenase -2.88129
OXA1L oxidase (cytochrome c) assembly 1-like -2.87874
RPS5 ribosomal protein S5 -2.84984
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -2.84686
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -2.80324
RPL22 ribosomal protein L22 -2.68234
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.63382
RPL4 ribosomal protein L4 -2.59959
DPH5 diphthamide biosynthesis 5 -2.5015
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.49765
ARHGAP29 Rho GTPase activating protein 29 -2.47278
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.43055
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.42472
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.40594
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.38911
TTC36 tetratricopeptide repeat domain 36 -2.35938
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -2.35756
MRPL4 mitochondrial ribosomal protein L4 -2.35125
ZHX2 zinc fingers and homeoboxes 2 -2.34851
UQCRB ubiquinol-cytochrome c reductase binding protein -2.33051
ZNF665 zinc finger protein 665 -2.32893
CUEDC2 CUE domain containing 2 -2.28768
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.2832
FAM162A family with sequence similarity 162, member A -2.27009
RPL10A ribosomal protein L10a -2.26956
METTL9 methyltransferase like 9 -2.25925
PCGF2 polycomb group ring finger 2 -2.23716
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.23697
DDHD2 DDHD domain containing 2 -2.23297
PRCC papillary renal cell carcinoma (translocation-associated) -2.22856
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -2.22523
RDX radixin -2.22504
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.21789
CAPN3 calpain 3, (p94) -2.21062
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.20323
TNNC1 troponin C type 1 (slow) -2.19448
ADIPOR2 adiponectin receptor 2 -2.1942
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.18366
MTMR4 myotubularin related protein 4 -2.17999
FBXO46 F-box protein 46 -2.17981
GAPT GRB2-binding adaptor protein, transmembrane -2.17511
RPL15 ribosomal protein L15 -2.16808
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -2.16622
QSER1 glutamine and serine rich 1 -2.15743
NCOR1 nuclear receptor corepressor 1 -2.15734
MED12 mediator complex subunit 12 -2.15649
ISCA1 iron-sulfur cluster assembly 1 -2.15222
RPS28 ribosomal protein S28 -2.14916
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.1437
RPL13 ribosomal protein L13 -2.12754
DNMBP dynamin binding protein -2.12277
SNUPN snurportin 1 -2.12242
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.11881
FBXW2 F-box and WD repeat domain containing 2 -2.11649
BZW2 basic leucine zipper and W2 domains 2 -2.1131
WWC1 WW and C2 domain containing 1 -2.10328
PPP6R2 protein phosphatase 6, regulatory subunit 2 -2.103
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -2.06208
IPO5 importin 5 -2.05594
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.05229
SOS1 son of sevenless homolog 1 (Drosophila) -2.03748
ACOT11 acyl-CoA thioesterase 11 -2.03496
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -2.03358
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.03312
ABHD14A abhydrolase domain containing 14A -2.03237
PTCD3 pentatricopeptide repeat domain 3 -2.02965
MRPL15 mitochondrial ribosomal protein L15 -2.01151
GABARAPL2 GABA(A) receptor-associated protein-like 2 -2.00397
PTGDR2 prostaglandin D2 receptor 2 -2.00156
ERLIN2 ER lipid raft associated 2 -1.99705
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.98865
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.98762
TOR1AIP1 torsin A interacting protein 1 -1.98715
LIM2 lens intrinsic membrane protein 2, 19kDa -1.98018
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -1.96918
C1QBP complement component 1, q subcomponent binding protein -1.96567
GFOD1 glucose-fructose oxidoreductase domain containing 1 -1.96506
SUMO3 small ubiquitin-like modifier 3 -1.96076
LARP4B La ribonucleoprotein domain family, member 4B -1.95345
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -1.95289
R3HDM2 R3H domain containing 2 -1.95264
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.95127
TARBP1 TAR (HIV-1) RNA binding protein 1 -1.94794
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.94759
ELAVL1 ELAV like RNA binding protein 1 -1.94155
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.93093
DLD dihydrolipoamide dehydrogenase -1.93079
FRY furry homolog (Drosophila) -1.92985
GSTM4 glutathione S-transferase mu 4 -1.92923
RPL31 ribosomal protein L31 -1.92521
UXS1 UDP-glucuronate decarboxylase 1 -1.92426
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.91317
WDR82 WD repeat domain 82 -1.91252
GM2A GM2 ganglioside activator -1.9097
MOSPD2 motile sperm domain containing 2 -1.90711
MYL2 myosin, light chain 2, regulatory, cardiac, slow -1.906
MOAP1 modulator of apoptosis 1 -1.89087
THRB thyroid hormone receptor, beta -1.89038
PARP1 poly (ADP-ribose) polymerase 1 -1.88994
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -1.88492
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -1.8812
TTN titin -1.88093
MAML3 mastermind-like 3 (Drosophila) -1.87774
FEN1 flap structure-specific endonuclease 1 -1.8655
ATXN10 ataxin 10 -1.86272
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.8579
PRH1 proline-rich protein HaeIII subfamily 1 -1.85732
SEPT7 septin 7 -1.85354
COQ3 coenzyme Q3 methyltransferase -1.84563
BSDC1 BSD domain containing 1 -1.83973
KDM6A lysine (K)-specific demethylase 6A -1.83578
PLA2G2D phospholipase A2, group IID -1.83367
SEC23A Sec23 homolog A (S. cerevisiae) -1.8306
KIAA0430 KIAA0430 -1.82675
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.82427
DOLPP1 dolichyldiphosphatase 1 -1.82331
TM6SF1 transmembrane 6 superfamily member 1 -1.82317
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -1.8212
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) -1.82068
HSBP1 heat shock factor binding protein 1 -1.81922
GLTSCR2 glioma tumor suppressor candidate region gene 2 -1.81745
ISOC1 isochorismatase domain containing 1 -1.80871
ESD esterase D -1.80496
PFDN5 prefoldin subunit 5 -1.80476
PNPLA4 patatin-like phospholipase domain containing 4 -1.80007
C21ORF2 chromosome 21 open reading frame 2 -1.79817
ASXL1 additional sex combs like transcriptional regulator 1 -1.79294
CYB5R1 cytochrome b5 reductase 1 -1.79241
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -1.79076
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.78602
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -1.78452
FASTKD1 FAST kinase domains 1 -1.78248
EMP2 epithelial membrane protein 2 -1.78121
SLC44A5 solute carrier family 44, member 5 -1.77997
PRMT2 protein arginine methyltransferase 2 -1.77562
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -1.77179
ST7 suppression of tumorigenicity 7 -1.76706
MLH1 mutL homolog 1 -1.76692
AP2B1 adaptor-related protein complex 2, beta 1 subunit -1.76658
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) -1.76541
WDR47 WD repeat domain 47 -1.76146
GIN1 gypsy retrotransposon integrase 1 -1.75216
USPL1 ubiquitin specific peptidase like 1 -1.74969
DGCR8 DGCR8 microprocessor complex subunit -1.74524
SSTR2 somatostatin receptor 2 -1.74367
ARSE arylsulfatase E (chondrodysplasia punctata 1) -1.73964
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.73901
PLN phospholamban -1.73526
RUSC2 RUN and SH3 domain containing 2 -1.72662
HIST1H3C histone cluster 1, H3c -1.72368
OXCT1 3-oxoacid CoA transferase 1 -1.72302
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 -1.71873
KDM4C lysine (K)-specific demethylase 4C -1.71808
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.71794
AKAP8 A kinase (PRKA) anchor protein 8 -1.71537
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -1.70885
CEP57 centrosomal protein 57kDa -1.70603
UQCRH ubiquinol-cytochrome c reductase hinge protein -1.70463
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.70224
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -1.702
GPD1L glycerol-3-phosphate dehydrogenase 1-like -1.69627
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.69621
RASL12 RAS-like, family 12 -1.69437
MOCS2 molybdenum cofactor synthesis 2 -1.69434
CEP70 centrosomal protein 70kDa -1.69339
GOLGB1 golgin B1 -1.69211
SUCLG1 succinate-CoA ligase, alpha subunit -1.69164
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -1.68945
CDC16 cell division cycle 16 -1.68727
MLH3 mutL homolog 3 -1.68165
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.68144
HLTF helicase-like transcription factor -1.68063
LITAF lipopolysaccharide-induced TNF factor -1.67806
ENDOG endonuclease G -1.67565
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.67553
NOLC1 nucleolar and coiled-body phosphoprotein 1 -1.67359
MYO15B myosin XVB -1.6725
CC2D2B coiled-coil and C2 domain containing 2B -1.67097
CREM cAMP responsive element modulator -1.66629
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -1.66606
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -1.66507
ZFX zinc finger protein, X-linked -1.66324
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -1.66218
ACTN2 actinin, alpha 2 -1.6603
TRAPPC2 trafficking protein particle complex 2 -1.65786
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.65546
DLC1 DLC1 Rho GTPase activating protein -1.64903
INHA inhibin, alpha -1.64719
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G -1.64711
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -1.6455
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -1.64352
ATG5 autophagy related 5 -1.64251
ACBD3 acyl-CoA binding domain containing 3 -1.64158
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -1.63846
DHCR7 7-dehydrocholesterol reductase -1.63802
RPL27 ribosomal protein L27 -1.63716
MRPS15 mitochondrial ribosomal protein S15 -1.63484
SMG7 SMG7 nonsense mediated mRNA decay factor -1.6325
RRAGB Ras-related GTP binding B -1.62554
SNTN sentan, cilia apical structure protein -1.62393
MRPL16 mitochondrial ribosomal protein L16 -1.62328
FAM192A family with sequence similarity 192, member A -1.62023
FAM175B family with sequence similarity 175, member B -1.61961
RSAD1 radical S-adenosyl methionine domain containing 1 -1.61954
MRPS18B mitochondrial ribosomal protein S18B -1.61922
PGPEP1 pyroglutamyl-peptidase I -1.61907
DCTD dCMP deaminase -1.61482
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -1.61378
MAML1 mastermind-like 1 (Drosophila) -1.61253
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -1.61064
TNNT1 troponin T type 1 (skeletal, slow) -1.6069
WDR55 WD repeat domain 55 -1.60664
RPL27A ribosomal protein L27a -1.60525
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.60257
RPL26 ribosomal protein L26 -1.60202
TBC1D2B TBC1 domain family, member 2B -1.6008
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -1.59981
SOX10 SRY (sex determining region Y)-box 10 -1.59894
CCNI cyclin I -1.59634
GPR182 G protein-coupled receptor 182 -1.59612
MRPS11 mitochondrial ribosomal protein S11 -1.59592
RPSA ribosomal protein SA -1.59562
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -1.59405
NUP107 nucleoporin 107kDa -1.5928
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -1.59266
CHMP3 charged multivesicular body protein 3 -1.59102
USP9X ubiquitin specific peptidase 9, X-linked -1.58708
DROSHA drosha, ribonuclease type III -1.58653
SEC14L5 SEC14-like 5 (S. cerevisiae) -1.5861
ACTA2 actin, alpha 2, smooth muscle, aorta -1.58481
LOC100506469 -1.58439
RPS20 ribosomal protein S20 -1.58378
FAM178A family with sequence similarity 178, member A -1.58213
COPS4 COP9 signalosome subunit 4 -1.58203
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 -1.58192
NHP2 NHP2 ribonucleoprotein -1.58176
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.58083
FGFR1OP FGFR1 oncogene partner -1.58052
ADAM19 ADAM metallopeptidase domain 19 -1.57977
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.57915
MYO7A myosin VIIA -1.57675
PTPRB protein tyrosine phosphatase, receptor type, B -1.5744
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -1.57434
COX7B cytochrome c oxidase subunit VIIb -1.57192
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -1.5716
WDR70 WD repeat domain 70 -1.56946
HYI hydroxypyruvate isomerase (putative) -1.5663
RNF144A ring finger protein 144A -1.56566
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -1.56471
ALAS1 5'-aminolevulinate synthase 1 -1.56401
TPM1 tropomyosin 1 (alpha) -1.56325
RPS6 ribosomal protein S6 -1.5605
PHYH phytanoyl-CoA 2-hydroxylase -1.55999
ESR2 estrogen receptor 2 (ER beta) -1.55807
RAB21 RAB21, member RAS oncogene family -1.55753
SUZ12 SUZ12 polycomb repressive complex 2 subunit -1.55561
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -1.55543
TMEM131 transmembrane protein 131 -1.55318
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -1.54951
RAD21 RAD21 homolog (S. pombe) -1.54906
TMED2 transmembrane emp24 domain trafficking protein 2 -1.54841
RS1 retinoschisin 1 -1.54808
TMEM108 transmembrane protein 108 -1.54767
DMD dystrophin -1.5425
ITGA9 integrin, alpha 9 -1.54249
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -1.53963
TPD52L2 tumor protein D52-like 2 -1.53918
USP15 ubiquitin specific peptidase 15 -1.53868
SIGLEC7 sialic acid binding Ig-like lectin 7 -1.53771
ZNHIT3 zinc finger, HIT-type containing 3 -1.53608
DHRS1 dehydrogenase/reductase (SDR family) member 1 -1.53278
NME5 NME/NM23 family member 5 -1.53208
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -1.53045
ARHGAP32 Rho GTPase activating protein 32 -1.52937
RPIA ribose 5-phosphate isomerase A -1.52591
PRDM12 PR domain containing 12 -1.52499
RBMS3 RNA binding motif, single stranded interacting protein 3 -1.52433
ARL1 ADP-ribosylation factor-like 1 -1.52363
CUL5 cullin 5 -1.52125
NSDHL NAD(P) dependent steroid dehydrogenase-like -1.51727
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.51584
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -1.51545
KRT8P12 keratin 8 pseudogene 12 -1.51394
ZNF239 zinc finger protein 239 -1.51372
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.50999
HARS2 histidyl-tRNA synthetase 2, mitochondrial -1.50984
KIAA0232 KIAA0232 -1.50911
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -1.50829
PRDX2 peroxiredoxin 2 -1.5081
UBE3A ubiquitin protein ligase E3A -1.50711
PAX4 paired box 4 -1.50691
AQP6 aquaporin 6, kidney specific -1.5066
HMG20A high mobility group 20A -1.50616
DGAT1 diacylglycerol O-acyltransferase 1 -1.5054
Funding