Dermatophytosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A cutaneous mycosis that results_in fungal infection located_in scalp, located_in glabrous skin, or located_in nail, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes, which have the ability to utilize keratin as a nutrient source. (Human Disease Ontology, DOID_8913)
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Genes

186 genes co-occuring with the disease Dermatophytosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SQLE squalene epoxidase 3.103
CARD9 caspase recruitment domain family, member 9 3.1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.591
CLEC6A C-type lectin domain family 6, member A 2.553
CLEC7A C-type lectin domain family 7, member A 2.48
CLEC4E C-type lectin domain family 4, member E 2.249
CD4 CD4 molecule 2.133
IL17A interleukin 17A 2.133
DEFB4A defensin, beta 4A 1.984
IL22 interleukin 22 1.973
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.939
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.933
TNF tumor necrosis factor 1.921
IFNG interferon, gamma 1.901
TEF thyrotrophic embryonic factor 1.878
CLEC4D C-type lectin domain family 4, member D 1.877
IL1B interleukin 1, beta 1.866
IL17F interleukin 17F 1.829
IL6 interleukin 6 1.824
BCL10 B-cell CLL/lymphoma 10 1.824
TRIR telomerase RNA component interacting RNase 1.801
FLG filaggrin 1.78
CAMP cathelicidin antimicrobial peptide 1.764
IL12RB1 interleukin 12 receptor, beta 1 1.762
STAT1 signal transducer and activator of transcription 1, 91kDa 1.753
IL17RA interleukin 17 receptor A 1.751
RNASE7 ribonuclease, RNase A family, 7 1.747
S100A7 S100 calcium binding protein A7 1.734
FLG2 filaggrin family member 2 1.731
SYK spleen tyrosine kinase 1.711
SUB1 SUB1 homolog (S. cerevisiae) 1.692
AIRE autoimmune regulator 1.691
MALT1 MALT1 paracaspase 1.676
CXCL8 chemokine (C-X-C motif) ligand 8 1.675
CRP C-reactive protein, pentraxin-related 1.674
TLR2 toll-like receptor 2 1.659
CD8A CD8a molecule 1.619
IL17RC interleukin 17 receptor C 1.616
DOCK8 dedicator of cytokinesis 8 1.616
IL10 interleukin 10 1.615
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.606
IL1A interleukin 1, alpha 1.597
IL4 interleukin 4 1.584
RPL10 ribosomal protein L10 1.554
DEFB103A defensin, beta 103A 1.552
CARD14 caspase recruitment domain family, member 14 1.51
SPINK5 serine peptidase inhibitor, Kazal type 5 1.464
IL31 interleukin 31 1.462
TLR4 toll-like receptor 4 1.448
TINAG tubulointerstitial nephritis antigen 1.447
ALB albumin 1.444
DEFB4B defensin, beta 4B 1.443
IL2 interleukin 2 1.419
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.406
TRIM62 tripartite motif containing 62 1.391
DSG3 desmoglein 3 1.391
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.389
IL13 interleukin 13 1.388
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.388
INS insulin 1.367
DHODH dihydroorotate dehydrogenase (quinone) 1.355
IFNA1 interferon, alpha 1 1.349
NUP210L nucleoporin 210kDa-like 1.343
PTCH1 patched 1 1.34
CARD11 caspase recruitment domain family, member 11 1.34
LTF lactotransferrin 1.335
TRIM4 tripartite motif containing 4 1.334
DCD dermcidin 1.333
IVL involucrin 1.33
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 1.33
KRT9 keratin 9, type I 1.317
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.31
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.31
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.307
DEFB1 defensin, beta 1 1.296
CD209 CD209 molecule 1.293
CD1C CD1c molecule 1.286
TYK2 tyrosine kinase 2 1.276
CD207 CD207 molecule, langerin 1.27
KRT1 keratin 1, type II 1.258
IL36RN interleukin 36 receptor antagonist 1.252
ZNF347 zinc finger protein 347 1.248
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.247
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.246
CD1B CD1b molecule 1.245
IL5 interleukin 5 1.244
CD1E CD1e molecule 1.241
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.239
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.234
CD1A CD1a molecule 1.23
TGFB1 transforming growth factor, beta 1 1.226
LCE4A late cornified envelope 4A 1.221
TRAF3IP2 TRAF3 interacting protein 2 1.218
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.214
ADGRL1 adhesion G protein-coupled receptor L1 1.212
TP53 tumor protein p53 1.206
NF2 neurofibromin 2 (merlin) 1.205
CARMIL2 capping protein regulator and myosin 1 linker 2 1.201
KRT7 keratin 7, type II 1.199
CALML4 calmodulin-like 4 1.197
CALML6 calmodulin-like 6 1.197
CALML3 calmodulin-like 3 1.195
DSG1 desmoglein 1 1.194
CALML5 calmodulin-like 5 1.194
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.193
ZNF341 zinc finger protein 341 1.189
CD1D CD1d molecule 1.181
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.176
DCLK3 doublecortin-like kinase 3 1.169
CSF3 colony stimulating factor 3 (granulocyte) 1.159
NLRP3 NLR family, pyrin domain containing 3 1.155
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 1.154
MYD88 myeloid differentiation primary response 88 1.152
IFNA16 interferon, alpha 16 1.151
IFNA7 interferon, alpha 7 1.15
IFNA14 interferon, alpha 14 1.15
IFNA21 interferon, alpha 21 1.15
IFNA10 interferon, alpha 10 1.15
IFNA8 interferon, alpha 8 1.149
IFNA6 interferon, alpha 6 1.149
IFNA5 interferon, alpha 5 1.148
IFNA13 interferon, alpha 13 1.147
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.146
IFNA4 interferon, alpha 4 1.145
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.14
IFNA17 interferon, alpha 17 1.14
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.139
CARD10 caspase recruitment domain family, member 10 1.136
SLA2 Src-like-adaptor 2 1.136
JUN jun proto-oncogene 1.133
TECR trans-2,3-enoyl-CoA reductase 1.131
KLK5 kallikrein-related peptidase 5 1.131
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.13
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.13
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.13
TAC1 tachykinin, precursor 1 1.128
ADGRL2 adhesion G protein-coupled receptor L2 1.126
RFXANK regulatory factor X-associated ankyrin-containing protein 1.123
MSMO1 methylsterol monooxygenase 1 1.123
GSTM4 glutathione S-transferase mu 4 1.115
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 1.114
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.109
ZNF174 zinc finger protein 174 1.107
KLK7 kallikrein-related peptidase 7 1.1
ACHE acetylcholinesterase (Yt blood group) 1.099
IFNA2 interferon, alpha 2 1.099
TLR6 toll-like receptor 6 1.098
ELN elastin 1.092
FAP fibroblast activation protein, alpha 1.087
CLEC1A C-type lectin domain family 1, member A 1.084
TSLP thymic stromal lymphopoietin 1.078
IL23A interleukin 23, alpha subunit p19 1.077
PPA2 pyrophosphatase (inorganic) 2 1.077
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 1.073
CXCL2 chemokine (C-X-C motif) ligand 2 1.07
DST dystonin 1.07
PCSK6 proprotein convertase subtilisin/kexin type 6 1.069
HTN3 histatin 3 1.064
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 1.062
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.062
GATA2 GATA binding protein 2 1.059
BCHE butyrylcholinesterase 1.055
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.045
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.04
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.034
GPX6 glutathione peroxidase 6 1.033
GPX5 glutathione peroxidase 5 1.032
GPX8 glutathione peroxidase 8 (putative) 1.032
KATNAL2 katanin p60 subunit A-like 2 1.029
GPX7 glutathione peroxidase 7 1.029
TLR1 toll-like receptor 1 1.028
JAK1 Janus kinase 1 1.028
IL36R interleukin 36 receptor 1.026
TMPRSS5 transmembrane protease, serine 5 1.025
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.023
ICAM1 intercellular adhesion molecule 1 1.022
MPO myeloperoxidase 1.022
CXCL10 chemokine (C-X-C motif) ligand 10 1.022
TCHH trichohyalin 1.02
GPX2 glutathione peroxidase 2 1.019
NCF4 neutrophil cytosolic factor 4, 40kDa 1.016
GPX3 glutathione peroxidase 3 1.01
MRGPRX1 MAS-related GPR, member X1 1.009
CCL20 chemokine (C-C motif) ligand 20 1.007
COL17A1 collagen, type XVII, alpha 1 1.005
CD7 CD7 molecule 1.0