Desloratadine Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. (Chemical Entities of Biological Interest Ontology, CHEBI_291342)
External Link http://www.hmdb.ca/metabolites/HMDB15102
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Genes

6 interacting proteins for the Desloratadine metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
HRH1 histamine receptor H1