| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dexamethasone_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.33096 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.261217 |
| PLAT | plasminogen activator, tissue | 0.0969689 |
| GPC5 | glypican 5 | 0.0530485 |
| DPH6 | diphthamine biosynthesis 6 | 0.0508166 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0492183 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0479037 |
| KLF9 | Kruppel-like factor 9 | 0.0451145 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0438396 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0427666 |
| TOP1 | topoisomerase (DNA) I | 0.0393672 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0361311 |
| CTSB | cathepsin B | 0.0351987 |
| FNBP1 | formin binding protein 1 | 0.0339878 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0337084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.033478 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0320375 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0312063 |
| HMGA2 | high mobility group AT-hook 2 | 0.0294964 |
| PTMA | prothymosin, alpha | 0.0290821 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0288248 |
| MYO6 | myosin VI | 0.0271441 |
| FAM13A | family with sequence similarity 13, member A | 0.0265791 |
| LPIN1 | lipin 1 | 0.0257764 |
| RPL19 | ribosomal protein L19 | 0.0255274 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0248058 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0242902 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0241977 |
| GDF15 | growth differentiation factor 15 | 0.0238711 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0236567 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0234057 |
| SEPTIN2 | septin 2 | 0.0231714 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0227206 |
| USP53 | ubiquitin specific peptidase 53 | 0.0225744 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0223386 |
| VIM | vimentin | 0.0223157 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0222934 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0221386 |
| FKBP5 | FK506 binding protein 5 | 0.0219138 |
| SCG2 | secretogranin II | 0.0218262 |
| WDR43 | WD repeat domain 43 | 0.0214414 |
| HMGA1 | high mobility group AT-hook 1 | 0.0212007 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0208144 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0206707 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0206151 |
| EPAS1 | endothelial PAS domain protein 1 | 0.02058 |
| UBC | ubiquitin C | 0.0203144 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0202431 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0201188 |
| RGS4 | regulator of G-protein signaling 4 | 0.0200968 |
| B2M | beta-2-microglobulin | 0.0200863 |
| RPL36 | ribosomal protein L36 | 0.02007 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0199823 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0199264 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.019575 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0194189 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0191009 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0189367 |
| MLXIP | MLX interacting protein | 0.0189294 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0186843 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0184185 |
| PHIP | pleckstrin homology domain interacting protein | 0.0183299 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0182284 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.018217 |
| TXNRD1 | thioredoxin reductase 1 | 0.0182076 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0181168 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.017847 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0177456 |
| COPS2 | COP9 signalosome subunit 2 | 0.0176774 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0174826 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0172001 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0171748 |
| RPLP0 | ribosomal protein, large, P0 | 0.0171511 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0171106 |
| HIP1 | huntingtin interacting protein 1 | 0.0169181 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.0167979 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0165086 |
| RO60 | Ro60, Y RNA binding protein | 0.0164624 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0164327 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0162235 |
| NPR2 | natriuretic peptide receptor 2 | 0.0162138 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0161473 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0160187 |
| CALU | calumenin | 0.0159412 |
| MCL1 | myeloid cell leukemia 1 | 0.0159043 |
| RPL8 | ribosomal protein L8 | 0.0158622 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.015815 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0157808 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0156694 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0156444 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0156071 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0154059 |
| YTHDC1 | YTH domain containing 1 | 0.0153952 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0153078 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0152441 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0151651 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0151515 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0150294 |
| AFDN | afadin, adherens junction formation factor | 0.0149849 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0148049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYT1 | synaptotagmin I | -0.142033 |
| LSAMP | limbic system-associated membrane protein | -0.128746 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.104292 |
| VCL | vinculin | -0.097278 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.095457 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0930358 |
| MEIS2 | Meis homeobox 2 | -0.0703798 |
| TLE4 | transducin-like enhancer of split 4 | -0.069264 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0671671 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0668438 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.065856 |
| PRKCA | protein kinase C, alpha | -0.0635977 |
| ZNF804A | zinc finger protein 804A | -0.0601198 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0596978 |
| MED13 | mediator complex subunit 13 | -0.058458 |
| CENPF | centromere protein F, 350/400kDa | -0.0551411 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0537233 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0537072 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0532002 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0531419 |
| RNF213 | ring finger protein 213 | -0.0503042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0481454 |
| PLPP1 | phospholipid phosphatase 1 | -0.0478181 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0473435 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0464298 |
| GLCCI1 | glucocorticoid induced 1 | -0.046221 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0452877 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0447955 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0444778 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0437586 |
| NREP | neuronal regeneration related protein | -0.0437106 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0435369 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0435199 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0431534 |
| DNM3 | dynamin 3 | -0.0411188 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0398343 |
| KLHL13 | kelch-like family member 13 | -0.0387694 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0382785 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0374396 |
| TPM4 | tropomyosin 4 | -0.0371844 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0369771 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0356374 |
| CUX1 | cut-like homeobox 1 | -0.035538 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0353821 |
| PDE10A | phosphodiesterase 10A | -0.0349599 |
| TRIB2 | tribbles pseudokinase 2 | -0.0346856 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0344898 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0341613 |
| ATXN1 | ataxin 1 | -0.0340232 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0339986 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0338776 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0338067 |
| EXOC4 | exocyst complex component 4 | -0.0336094 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0334457 |
| BPTF | bromodomain PHD finger transcription factor | -0.0333323 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0333181 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0330996 |
| TENM4 | teneurin transmembrane protein 4 | -0.032963 |
| SIK2 | salt-inducible kinase 2 | -0.0328556 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0328311 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0325914 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0323832 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0323295 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0321255 |
| PCDH9 | protocadherin 9 | -0.0321065 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0320514 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0315518 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0314179 |
| FRMD4A | FERM domain containing 4A | -0.0312459 |
| GOLGB1 | golgin B1 | -0.0311657 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0309649 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0304473 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.030309 |
| TPM1 | tropomyosin 1 (alpha) | -0.0300855 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0299437 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0297636 |
| PTEN | phosphatase and tensin homolog | -0.0293435 |
| CADM2 | cell adhesion molecule 2 | -0.0292594 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0292551 |
| AUTS2 | autism susceptibility candidate 2 | -0.0286859 |
| HMBOX1 | homeobox containing 1 | -0.0285759 |
| INTS6 | integrator complex subunit 6 | -0.0283794 |
| DST | dystonin | -0.0281481 |
| STK38L | serine/threonine kinase 38 like | -0.0279713 |
| TOX | thymocyte selection-associated high mobility group box | -0.0279303 |
| RPS6 | ribosomal protein S6 | -0.0278095 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0275313 |
| PCBP2 | poly(rC) binding protein 2 | -0.0270188 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0269956 |
| MKI67 | marker of proliferation Ki-67 | -0.0268656 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma | -0.0268295 |
| CADM1 | cell adhesion molecule 1 | -0.0267235 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.026723 |
| DACH2 | dachshund family transcription factor 2 | -0.0267196 |
| EGR1 | early growth response 1 | -0.0264076 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0261604 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0257869 |
| VMP1 | vacuole membrane protein 1 | -0.0256843 |
| RAD51B | RAD51 paralog B | -0.0255671 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0252884 |