| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.130983 |
| TXNIP | thioredoxin interacting protein | 0.101052 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0926238 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0894313 |
| B2M | beta-2-microglobulin | 0.0830913 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0787432 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0784432 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.073736 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0718997 |
| TMC5 | transmembrane channel-like 5 | 0.0620239 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.060799 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0601057 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0560257 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0545769 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0528269 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0500425 |
| RNF149 | ring finger protein 149 | 0.0475848 |
| STK24 | serine/threonine kinase 24 | 0.0471222 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0458842 |
| IL20RA | interleukin 20 receptor, alpha | 0.044825 |
| MEIS2 | Meis homeobox 2 | 0.0426698 |
| DSTN | destrin (actin depolymerizing factor) | 0.0422547 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0421029 |
| BPTF | bromodomain PHD finger transcription factor | 0.0415548 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0409467 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0406206 |
| MYO1E | myosin IE | 0.0398334 |
| TMEM51 | transmembrane protein 51 | 0.0397346 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0394821 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0389622 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0388463 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0386975 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0386076 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0384614 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0383148 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0376831 |
| ENO1 | enolase 1, (alpha) | 0.0375653 |
| DSPP | dentin sialophosphoprotein | 0.0372733 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0368739 |
| ERBIN | erbb2 interacting protein | 0.0359118 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0356079 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0354831 |
| OCLN | occludin | 0.0354559 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0352573 |
| ABHD2 | abhydrolase domain containing 2 | 0.0349371 |
| MKI67 | marker of proliferation Ki-67 | 0.0339383 |
| PTEN | phosphatase and tensin homolog | 0.033781 |
| TMEM62 | transmembrane protein 62 | 0.0336949 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0336186 |
| EHF | ets homologous factor | 0.0332077 |
| DSCAM | Down syndrome cell adhesion molecule | 0.033116 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0327445 |
| EPCAM | epithelial cell adhesion molecule | 0.0327231 |
| NMU | neuromedin U | 0.0327167 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0324352 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0323665 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0322449 |
| PTMA | prothymosin, alpha | 0.0315771 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0314923 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0312981 |
| TPM4 | tropomyosin 4 | 0.0301914 |
| ITGA6 | integrin, alpha 6 | 0.030077 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0291754 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0291013 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0287816 |
| IFNGR1 | interferon gamma receptor 1 | 0.0287698 |
| PRELID2 | PRELI domain containing 2 | 0.028573 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0285192 |
| GOLGA2 | golgin A2 | 0.0284855 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0284098 |
| OGA | O-GlcNAcase | 0.0284022 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.028226 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.02795 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0279329 |
| TAOK3 | TAO kinase 3 | 0.0278455 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0275657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0275473 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0275242 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0275005 |
| FHL2 | four and a half LIM domains 2 | 0.0271002 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0269277 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268578 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0267102 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.026431 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0263184 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0263075 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0262961 |
| KLF6 | Kruppel-like factor 6 | 0.0260339 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0249975 |
| SBF2 | SET binding factor 2 | 0.0248675 |
| KRT19 | keratin 19, type I | 0.0248409 |
| RUNX1 | runt-related transcription factor 1 | 0.024725 |
| GGNBP2 | gametogenetin binding protein 2 | 0.024684 |
| ZNF395 | zinc finger protein 395 | 0.0246423 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0246249 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.02462 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0243865 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0243799 |
| DNM2 | dynamin 2 | 0.0242917 |
| RPS6 | ribosomal protein S6 | 0.0240458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.167393 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.115432 |
| RNF213 | ring finger protein 213 | -0.103866 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0990689 |
| ANXA2 | annexin A2 | -0.0949196 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0932006 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0891036 |
| RIGI | RNA sensor RIG-I | -0.0887968 |
| PLSCR2 | phospholipid scramblase 2 | -0.0873191 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0865475 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0859689 |
| SQSTM1 | sequestosome 1 | -0.0812053 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0799832 |
| EGR1 | early growth response 1 | -0.0752138 |
| SP100 | SP100 nuclear antigen | -0.0738336 |
| LMO7 | LIM domain 7 | -0.072214 |
| MX1 | MX dynamin-like GTPase 1 | -0.0646648 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0619797 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0617993 |
| LAMA4 | laminin, alpha 4 | -0.0589022 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0575312 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0568796 |
| SMAD3 | SMAD family member 3 | -0.056092 |
| PLSCR1 | phospholipid scramblase 1 | -0.0548529 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0528687 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0506231 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0489566 |
| MX2 | MX dynamin-like GTPase 2 | -0.0470456 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0461838 |
| UBAP2 | ubiquitin associated protein 2 | -0.0439878 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0434808 |
| NABP1 | nucleic acid binding protein 1 | -0.0425965 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0424511 |
| PKM | pyruvate kinase, muscle | -0.0416065 |
| HKDC1 | hexokinase domain containing 1 | -0.0415989 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0410809 |
| ASPH | aspartate beta-hydroxylase | -0.0395517 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0394102 |
| VCL | vinculin | -0.0377092 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.037619 |
| MAP7 | microtubule-associated protein 7 | -0.0373451 |
| EPHB2 | EPH receptor B2 | -0.0370398 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0368759 |
| MCL1 | myeloid cell leukemia 1 | -0.0364874 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0364728 |
| SDC4 | syndecan 4 | -0.0364443 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0361933 |
| FBXO39 | F-box protein 39 | -0.0358874 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0354593 |
| MSI2 | musashi RNA-binding protein 2 | -0.0352261 |
| POU2F2 | POU class 2 homeobox 2 | -0.0350791 |
| VMP1 | vacuole membrane protein 1 | -0.0348722 |
| HOMER1 | homer scaffolding protein 1 | -0.0345749 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0345195 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0335579 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0333446 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0330472 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0330377 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0330273 |
| PHF3 | PHD finger protein 3 | -0.0316744 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.031175 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0311497 |
| MUC20 | mucin 20, cell surface associated | -0.0307632 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0306399 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0305581 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0299418 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0294219 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0290635 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0284365 |
| APP | amyloid beta (A4) precursor protein | -0.0283355 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0280056 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0275401 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0270088 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0267347 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0266758 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0265557 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | -0.0263824 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0263734 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0262174 |
| PRKCA | protein kinase C, alpha | -0.0254577 |
| SDCBP | syndecan binding protein (syntenin) | -0.0252331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.025086 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0249585 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0246834 |
| RCOR1 | REST corepressor 1 | -0.0246189 |
| TNS4 | tensin 4 | -0.0240958 |
| ZNF292 | zinc finger protein 292 | -0.0240761 |
| FNIP1 | folliculin interacting protein 1 | -0.0240481 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0240272 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0237887 |
| SIL1 | SIL1 nucleotide exchange factor | -0.0236839 |
| HLA-C | major histocompatibility complex, class I, C | -0.0235055 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0234451 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0230803 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0229803 |
| POF1B | premature ovarian failure, 1B | -0.022976 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0228127 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0227327 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0227077 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0223158 |
