| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.396854 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.274798 |
| APOB | apolipoprotein B | 0.266317 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.174381 |
| MT2A | metallothionein 2A | 0.124375 |
| GPC3 | glypican 3 | 0.0958527 |
| ENO1 | enolase 1, (alpha) | 0.0838543 |
| C3 | complement component 3 | 0.0831746 |
| DSPP | dentin sialophosphoprotein | 0.0812863 |
| FN1 | fibronectin 1 | 0.0775898 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0712717 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.070627 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0549334 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0518912 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.05091 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0507378 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0504088 |
| RPS6 | ribosomal protein S6 | 0.0469935 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0467761 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0448206 |
| TRIM26 | tripartite motif containing 26 | 0.0446552 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0435705 |
| TF | transferrin | 0.0435216 |
| FGG | fibrinogen gamma chain | 0.0432395 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0430303 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0404954 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0399079 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039892 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0393352 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0390884 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0386578 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0382737 |
| APOE | apolipoprotein E | 0.0381122 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0378743 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0348685 |
| RBM39 | RNA binding motif protein 39 | 0.0345947 |
| AFDN | afadin, adherens junction formation factor | 0.0336791 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0327619 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0317065 |
| A2M | alpha-2-macroglobulin | 0.0315196 |
| CPE | carboxypeptidase E | 0.0303441 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0293533 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0291179 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0289677 |
| RPL11 | ribosomal protein L11 | 0.0282699 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0280179 |
| KIF5B | kinesin family member 5B | 0.0278629 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0274055 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.0269444 |
| FGA | fibrinogen alpha chain | 0.0259221 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0256555 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0256095 |
| RPS12 | ribosomal protein S12 | 0.0255971 |
| FTL | ferritin, light polypeptide | 0.0254432 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0253191 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0248631 |
| OGA | O-GlcNAcase | 0.0248615 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0245329 |
| IFNGR1 | interferon gamma receptor 1 | 0.024225 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0240574 |
| CFB | complement factor B | 0.0239281 |
| ECE1 | endothelin converting enzyme 1 | 0.0238761 |
| MATN3 | matrilin 3 | 0.0233613 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231732 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0230504 |
| KIF1B | kinesin family member 1B | 0.0228755 |
| MATR3 | matrin 3 | 0.022736 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0226657 |
| APOA2 | apolipoprotein A-II | 0.0220167 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0219573 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0218465 |
| RPLP0 | ribosomal protein, large, P0 | 0.0217978 |
| PGK1 | phosphoglycerate kinase 1 | 0.0216935 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0216889 |
| APOA1 | apolipoprotein A-I | 0.0216537 |
| CTSB | cathepsin B | 0.0215584 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0214554 |
| FKBP5 | FK506 binding protein 5 | 0.0213552 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0213229 |
| PCM1 | pericentriolar material 1 | 0.020712 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0207043 |
| WDR45B | WD repeat domain 45B | 0.0206796 |
| PHIP | pleckstrin homology domain interacting protein | 0.0204332 |
| GOLGA4 | golgin A4 | 0.0203312 |
| FOXN3 | forkhead box N3 | 0.0203138 |
| SELENOP | selenoprotein P | 0.0202894 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0201973 |
| RACK1 | receptor for activated C kinase 1 | 0.0200428 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0198835 |
| CDK19 | cyclin-dependent kinase 19 | 0.019876 |
| RTN4 | reticulon 4 | 0.01987 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0198398 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0197458 |
| MED13L | mediator complex subunit 13-like | 0.01961 |
| RRBP1 | ribosome binding protein 1 | 0.0196063 |
| ZNF292 | zinc finger protein 292 | 0.0195226 |
| RBM25 | RNA binding motif protein 25 | 0.0194581 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0193955 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0193343 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.019218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.444506 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0964546 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0721083 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0661823 |
| EHBP1 | EH domain binding protein 1 | -0.066105 |
| ASPH | aspartate beta-hydroxylase | -0.0625854 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0610829 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0588316 |
| ATXN1 | ataxin 1 | -0.0548699 |
| FRMD5 | FERM domain containing 5 | -0.0472664 |
| INTS6 | integrator complex subunit 6 | -0.0447893 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0409871 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0404472 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0388359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0373974 |
| HMGA1 | high mobility group AT-hook 1 | -0.0370515 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0366216 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.03187 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0294284 |
| DTNA | dystrobrevin, alpha | -0.0292965 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0290634 |
| FAT1 | FAT atypical cadherin 1 | -0.028801 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0284303 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0283966 |
| EGR1 | early growth response 1 | -0.0283938 |
| DST | dystonin | -0.0275744 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0272573 |
| RNF213 | ring finger protein 213 | -0.0263068 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0262738 |
| NDRG1 | N-myc downstream regulated 1 | -0.0261237 |
| NHSL1 | NHS-like 1 | -0.0257687 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0256918 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0244796 |
| GK | glycerol kinase | -0.0241906 |
| MCL1 | myeloid cell leukemia 1 | -0.0238596 |
| PARD3 | par-3 family cell polarity regulator | -0.023272 |
| PRKCA | protein kinase C, alpha | -0.0232703 |
| RIGI | RNA sensor RIG-I | -0.0228967 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0226601 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0226495 |
| TMSB10 | thymosin beta 10 | -0.0224217 |
| ATP10A | ATPase, class V, type 10A | -0.0223286 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0221519 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0221355 |
| FOXP1 | forkhead box P1 | -0.022046 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0219775 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0218973 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0214918 |
| GPC6 | glypican 6 | -0.0212148 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0212 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0210318 |
| SP100 | SP100 nuclear antigen | -0.0208578 |
| JAG1 | jagged 1 | -0.0199259 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0194125 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0192589 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0189812 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0185859 |
| MSI2 | musashi RNA-binding protein 2 | -0.0184563 |
| VEGFA | vascular endothelial growth factor A | -0.0183549 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0182875 |
| FAM107B | family with sequence similarity 107, member B | -0.0178047 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0176767 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0173105 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0173033 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0170921 |
| ITGAV | integrin, alpha V | -0.0169286 |
| MYO1E | myosin IE | -0.0165925 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0164136 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0163691 |
| CMIP | c-Maf inducing protein | -0.01619 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0161813 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0160401 |
| TNS3 | tensin 3 | -0.0159306 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0155365 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0152852 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.015232 |
| FILIP1L | filamin A interacting protein 1-like | -0.0151789 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0147379 |
| CNKSR3 | CNKSR family member 3 | -0.0147348 |
| RASA2 | RAS p21 protein activator 2 | -0.0147049 |
| RUNX1 | runt-related transcription factor 1 | -0.0146813 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0144999 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0144666 |
| MX2 | MX dynamin-like GTPase 2 | -0.0143959 |
| HOMER1 | homer scaffolding protein 1 | -0.01437 |
| GLIS3 | GLIS family zinc finger 3 | -0.0140772 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0140691 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0139957 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0139783 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0138333 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0137733 |
| STK17A | serine/threonine kinase 17a | -0.0136114 |
| TRIM25 | tripartite motif containing 25 | -0.013599 |
| RASAL2 | RAS protein activator like 2 | -0.0135879 |
| SMAD3 | SMAD family member 3 | -0.0135701 |
| HPCAL1 | hippocalcin-like 1 | -0.0133754 |
| TNS1 | tensin 1 | -0.0133534 |
| FMNL2 | formin-like 2 | -0.0131145 |
| VCAN | versican | -0.013106 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0131042 |
