| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dexamethasone_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP5 | FK506 binding protein 5 | 0.192323 |
| TXNIP | thioredoxin interacting protein | 0.158285 |
| KRT6A | keratin 6A, type II | 0.113582 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0975936 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0930008 |
| ANXA1 | annexin A1 | 0.0923039 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0767366 |
| MT1X | metallothionein 1X | 0.0696627 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0662475 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0636674 |
| EZR | ezrin | 0.0624544 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.062006 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0591651 |
| CAPRIN2 | caprin family member 2 | 0.0583935 |
| HMGA2 | high mobility group AT-hook 2 | 0.057423 |
| IGF2 | insulin-like growth factor 2 | 0.053219 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0531284 |
| POTEF | POTE ankyrin domain family, member F | 0.0520712 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0508287 |
| VCL | vinculin | 0.049874 |
| GLUL | glutamate-ammonia ligase | 0.0484967 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0464261 |
| ZFHX3 | zinc finger homeobox 3 | 0.0453033 |
| NDRG1 | N-myc downstream regulated 1 | 0.0448522 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0420193 |
| FOXN2 | forkhead box N2 | 0.0409385 |
| MCL1 | myeloid cell leukemia 1 | 0.0407619 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0406065 |
| LAMB1 | laminin, beta 1 | 0.0401606 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0399801 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0379503 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0376715 |
| CDKL5 | cyclin-dependent kinase-like 5 | 0.036398 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0360512 |
| PHF20 | PHD finger protein 20 | 0.0346237 |
| AHNAK | AHNAK nucleoprotein | 0.03344 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.032586 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0305769 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0304581 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0303987 |
| WASF2 | WAS protein family, member 2 | 0.0303933 |
| IRS2 | insulin receptor substrate 2 | 0.0301557 |
| EGR1 | early growth response 1 | 0.030115 |
| CLU | clusterin | 0.0298443 |
| AFAP1L1 | actin filament associated protein 1-like 1 | 0.0286907 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0286746 |
| TES | testin LIM domain protein | 0.0283009 |
| ZHX3 | zinc fingers and homeoboxes 3 | 0.0282787 |
| KLF6 | Kruppel-like factor 6 | 0.0282119 |
| EFNA5 | ephrin-A5 | 0.0279327 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0277589 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0275869 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0275144 |
| RBM39 | RNA binding motif protein 39 | 0.0262516 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0262465 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.026064 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.026053 |
| TMEM165 | transmembrane protein 165 | 0.0255828 |
| KLF9 | Kruppel-like factor 9 | 0.0255389 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0255059 |
| EMP1 | epithelial membrane protein 1 | 0.0252527 |
| FBXO11 | F-box protein 11 | 0.0246505 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0245024 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0243281 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0243125 |
| CAVIN2 | caveolae associated protein 2 | 0.0238198 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236399 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0236158 |
| JPH2 | junctophilin 2 | 0.0235386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233819 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0231395 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0230963 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0229277 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0224981 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0224613 |
| NRCAM | neuronal cell adhesion molecule | 0.0221553 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0219749 |
| OGA | O-GlcNAcase | 0.0218094 |
| IL6ST | interleukin 6 signal transducer | 0.0216033 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0214519 |
| CUL4B | cullin 4B | 0.0214348 |
| CLMB | calcimembrin | 0.0214047 |
| KRT17 | keratin 17, type I | 0.0213081 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0210154 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0208321 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0207769 |
| MT2A | metallothionein 2A | 0.0207063 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0206021 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0205897 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0205226 |
| YAP1 | Yes-associated protein 1 | 0.0204766 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0201531 |
| PKP2 | plakophilin 2 | 0.0201137 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0200569 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0200561 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0197681 |
| ABHD2 | abhydrolase domain containing 2 | 0.0195487 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0194805 |
| MLKL | mixed lineage kinase domain-like | 0.0194669 |
| MYO1B | myosin IB | 0.0191581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.183917 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.153575 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.114983 |
| CD44 | CD44 molecule (Indian blood group) | -0.0925506 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0822337 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0799108 |
| ASPH | aspartate beta-hydroxylase | -0.0792696 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0784283 |
| MEF2A | myocyte enhancer factor 2A | -0.0728183 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.068368 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0635913 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0632198 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0621844 |
| AOPEP | aminopeptidase O (putative) | -0.061428 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0612682 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0598421 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0596281 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0584266 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0580969 |
| KIAA1217 | KIAA1217 | -0.0562777 |
| NRG1 | neuregulin 1 | -0.0559027 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0558637 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0550381 |
| PTMA | prothymosin, alpha | -0.0543552 |
| RPS8 | ribosomal protein S8 | -0.0537246 |
| SULF1 | sulfatase 1 | -0.0529926 |
| FOXO1 | forkhead box O1 | -0.052197 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0502038 |
| MECOM | MDS1 and EVI1 complex locus | -0.0491577 |
| TMSB4X | thymosin beta 4, X-linked | -0.0485103 |
| RPLP2 | ribosomal protein, large, P2 | -0.0482132 |
| RPS6 | ribosomal protein S6 | -0.0478216 |
| ITGA6 | integrin, alpha 6 | -0.0476955 |
| PODXL | podocalyxin-like | -0.0471917 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0470153 |
| MTSS1 | metastasis suppressor 1 | -0.0457405 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.045657 |
| DOK5 | docking protein 5 | -0.0455328 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0450503 |
| RAI14 | retinoic acid induced 14 | -0.0434416 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0432337 |
| RPLP1 | ribosomal protein, large, P1 | -0.0429703 |
| GNAS | GNAS complex locus | -0.0425705 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0424517 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0421981 |
| DST | dystonin | -0.0417484 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.041733 |
| RPL23 | ribosomal protein L23 | -0.0411187 |
| RPL11 | ribosomal protein L11 | -0.041084 |
| B2M | beta-2-microglobulin | -0.0410394 |
| RPS21 | ribosomal protein S21 | -0.0406928 |
| FLNB | filamin B, beta | -0.0402927 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0401574 |
| MYOF | myoferlin | -0.0400308 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0396834 |
| SMAD3 | SMAD family member 3 | -0.0392783 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0388613 |
| MYO10 | myosin X | -0.037069 |
| RIGI | RNA sensor RIG-I | -0.0369288 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0368462 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0366373 |
| PLEC | plectin | -0.0364014 |
| RPL26 | ribosomal protein L26 | -0.0361576 |
| BLCAP | bladder cancer associated protein | -0.0359114 |
| CANX | calnexin | -0.0354096 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0351944 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0350705 |
| SULF2 | sulfatase 2 | -0.0348469 |
| SYNJ2 | synaptojanin 2 | -0.0347509 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0347503 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0347018 |
| OSMR | oncostatin M receptor | -0.0345384 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.034463 |
| RPL12 | ribosomal protein L12 | -0.0344014 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0343492 |
| AMOTL1 | angiomotin like 1 | -0.0340718 |
| SQSTM1 | sequestosome 1 | -0.0340137 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0339905 |
| RPL37 | ribosomal protein L37 | -0.033908 |
| PRSS23 | protease, serine, 23 | -0.0338761 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0336685 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0335502 |
| RPL30 | ribosomal protein L30 | -0.0334911 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0333677 |
| RPL35A | ribosomal protein L35a | -0.0332891 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0332774 |
| HLA-B | major histocompatibility complex, class I, B | -0.033003 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0328624 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0328173 |
| YBX1 | Y box binding protein 1 | -0.0327621 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0323934 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0318231 |
| CMIP | c-Maf inducing protein | -0.0317895 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0316737 |
| RPS19 | ribosomal protein S19 | -0.0315298 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0310447 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0310221 |
| FRMD5 | FERM domain containing 5 | -0.0308734 |
| TMSB10 | thymosin beta 10 | -0.0297048 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0296465 |