| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0609154 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0543428 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513314 |
| MT1X | metallothionein 1X | 0.0455736 |
| FKBP5 | FK506 binding protein 5 | 0.0421972 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0361121 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0346374 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0321444 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0308517 |
| SRGN | serglycin | 0.0276748 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0269437 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0242619 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0240814 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0238502 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0235953 |
| MKI67 | marker of proliferation Ki-67 | 0.0217479 |
| MT1E | metallothionein 1E | 0.021619 |
| SET | SET nuclear proto-oncogene | 0.0205552 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0203206 |
| CAPRIN2 | caprin family member 2 | 0.0203003 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0198034 |
| YEATS2 | YEATS domain containing 2 | 0.0196026 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0193874 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0192404 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0191523 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0186932 |
| ANXA1 | annexin A1 | 0.0182481 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.018134 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0159282 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0158589 |
| DGKH | diacylglycerol kinase, eta | 0.0157399 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0157235 |
| IPO7 | importin 7 | 0.0154277 |
| SLC38A2 | solute carrier family 38, member 2 | 0.015377 |
| RPS6 | ribosomal protein S6 | 0.0152641 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0151769 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0149249 |
| SLK | STE20-like kinase | 0.0149206 |
| PKN2 | protein kinase N2 | 0.01488 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.014227 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0141769 |
| IL6ST | interleukin 6 signal transducer | 0.0141542 |
| RPS23 | ribosomal protein S23 | 0.0140813 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0138129 |
| KLF9 | Kruppel-like factor 9 | 0.0137357 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0135459 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0135437 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0134734 |
| HMGA1 | high mobility group AT-hook 1 | 0.0134534 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0133341 |
| KLHL24 | kelch-like family member 24 | 0.0133217 |
| HJURP | Holliday junction recognition protein | 0.0130381 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 0.0130087 |
| KIAA1958 | KIAA1958 | 0.0127419 |
| SMAP1 | small ArfGAP 1 | 0.0126183 |
| SBF2 | SET binding factor 2 | 0.0124911 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0123307 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0122122 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0121447 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0121027 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0120993 |
| MCL1 | myeloid cell leukemia 1 | 0.0120787 |
| USP34 | ubiquitin specific peptidase 34 | 0.0120492 |
| PLIN2 | perilipin 2 | 0.012002 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.011944 |
| TCP1 | t-complex 1 | 0.0119332 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0119179 |
| ANGPTL4 | angiopoietin-like 4 | 0.0117238 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0117015 |
| STXBP1 | syntaxin binding protein 1 | 0.0115606 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0115343 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.0113214 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0112362 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0111984 |
| ARF6 | ADP-ribosylation factor 6 | 0.0111759 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0110874 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0109496 |
| EREG | epiregulin | 0.0109242 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0108662 |
| NRDC | nardilysin convertase | 0.0108606 |
| RASA2 | RAS p21 protein activator 2 | 0.0108088 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.0107908 |
| STX2 | syntaxin 2 | 0.0107465 |
| RPS5 | ribosomal protein S5 | 0.0107464 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0107442 |
| HDGF | hepatoma-derived growth factor | 0.0105679 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0105548 |
| FBXO17 | F-box protein 17 | 0.0105409 |
| PANK3 | pantothenate kinase 3 | 0.0105111 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0105013 |
| FAM120A | family with sequence similarity 120A | 0.010442 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0104381 |
| ARFGEF3 | ARFGEF family member 3 | 0.0103461 |
| SNX3 | sorting nexin 3 | 0.0103389 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0102541 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0102085 |
| CPSF2 | cleavage and polyadenylation specific factor 2, 100kDa | 0.0101904 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0101049 |
| PHF3 | PHD finger protein 3 | 0.0101002 |
| POM121 | POM121 transmembrane nucleoporin | 0.0100171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204212 |
| TP63 | tumor protein p63 | -0.152182 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.144184 |
| CD44 | CD44 molecule (Indian blood group) | -0.143983 |
| DST | dystonin | -0.132245 |
| VIM | vimentin | -0.13147 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.124611 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.120465 |
| TMSB10 | thymosin beta 10 | -0.113006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111036 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.10797 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.103481 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0970362 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0969913 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0969807 |
| TMSB4X | thymosin beta 4, X-linked | -0.0863626 |
| RIGI | RNA sensor RIG-I | -0.0816923 |
| PTMA | prothymosin, alpha | -0.0738021 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0711299 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0701424 |
| SP100 | SP100 nuclear antigen | -0.0700058 |
| FMNL2 | formin-like 2 | -0.0699112 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0683817 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0673791 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0647349 |
| RUNX1 | runt-related transcription factor 1 | -0.064668 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0634064 |
| LDHA | lactate dehydrogenase A | -0.0612195 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0573523 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0533707 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0532597 |
| PDE10A | phosphodiesterase 10A | -0.052755 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0527517 |
| APP | amyloid beta (A4) precursor protein | -0.0521861 |
| EFNA5 | ephrin-A5 | -0.0519962 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0517057 |
| PGK1 | phosphoglycerate kinase 1 | -0.0510475 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0508903 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0476592 |
| HLA-B | major histocompatibility complex, class I, B | -0.0469161 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0458785 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0455371 |
| VCL | vinculin | -0.0445198 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0444827 |
| FBXO11 | F-box protein 11 | -0.0431786 |
| CMIP | c-Maf inducing protein | -0.0426233 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0425157 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.042483 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0424093 |
| CANX | calnexin | -0.0422251 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0422229 |
| TSC22D1 | TSC22 domain family, member 1 | -0.042083 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0420726 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0417904 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0417239 |
| OGA | O-GlcNAcase | -0.0412356 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0398638 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0394818 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0394752 |
| PLSCR1 | phospholipid scramblase 1 | -0.0394087 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0392109 |
| CADM2 | cell adhesion molecule 2 | -0.0389019 |
| RGS4 | regulator of G-protein signaling 4 | -0.0387836 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0375106 |
| PTK2 | protein tyrosine kinase 2 | -0.0372769 |
| RNF213 | ring finger protein 213 | -0.0369453 |
| EZR | ezrin | -0.0369433 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0368493 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0363743 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0363503 |
| LOXL2 | lysyl oxidase-like 2 | -0.0361198 |
| CALR | calreticulin | -0.0355991 |
| EPHA4 | EPH receptor A4 | -0.0351979 |
| SMAD3 | SMAD family member 3 | -0.0351214 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0346664 |
| JMJD1C | jumonji domain containing 1C | -0.0345312 |
| SMYD3 | SET and MYND domain containing 3 | -0.0339074 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0336152 |
| COL5A2 | collagen, type V, alpha 2 | -0.0334581 |
| FUS | FUS RNA binding protein | -0.0334434 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0331313 |
| H1-0 | H1.0 linker histone | -0.0325535 |
| TPI1 | triosephosphate isomerase 1 | -0.0325423 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0318228 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0317865 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0314376 |
| RBM39 | RNA binding motif protein 39 | -0.0314202 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0312234 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0312018 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.031089 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0304663 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300607 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0300498 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0298829 |
| SQSTM1 | sequestosome 1 | -0.0294336 |
| DENND5A | DENN/MADD domain containing 5A | -0.0289366 |
| TMEM41B | transmembrane protein 41B | -0.0287765 |
| BMERB1 | bMERB domain containing 1 | -0.028704 |
| MT2A | metallothionein 2A | -0.0286477 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284578 |
