| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dexamethasone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.357362 |
| PM20D1 | peptidase M20 domain containing 1 | 0.287965 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.130489 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.12032 |
| NNMT | nicotinamide N-methyltransferase | 0.0899735 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0865681 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.076443 |
| FGA | fibrinogen alpha chain | 0.0727058 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0697303 |
| FGB | fibrinogen beta chain | 0.0682338 |
| MT1X | metallothionein 1X | 0.0681497 |
| SRGN | serglycin | 0.0609159 |
| UTRN | utrophin | 0.0573793 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0513126 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0470902 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0453966 |
| KLF6 | Kruppel-like factor 6 | 0.0398698 |
| WWOX | WW domain containing oxidoreductase | 0.039093 |
| FGG | fibrinogen gamma chain | 0.0390426 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0369507 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0364921 |
| EFNA5 | ephrin-A5 | 0.0356983 |
| BICC1 | BicC family RNA binding protein 1 | 0.033902 |
| RAD51B | RAD51 paralog B | 0.0331113 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0326634 |
| ANGPTL4 | angiopoietin-like 4 | 0.0299018 |
| JAK1 | Janus kinase 1 | 0.0298025 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0291743 |
| IGF2 | insulin-like growth factor 2 | 0.0288546 |
| NFIA | nuclear factor I/A | 0.0265311 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0250163 |
| FAM135A | family with sequence similarity 135, member A | 0.0245588 |
| PHF20 | PHD finger protein 20 | 0.0242086 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0229651 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0224294 |
| LDHA | lactate dehydrogenase A | 0.0215656 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0214989 |
| NTN4 | netrin 4 | 0.021389 |
| CD109 | CD109 molecule | 0.0204237 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0201287 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0198806 |
| NEBL | nebulette | 0.0198303 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.019805 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0197673 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.019758 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0195579 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0195379 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0194303 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0191203 |
| GPC6 | glypican 6 | 0.0189161 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0188921 |
| ZFHX3 | zinc finger homeobox 3 | 0.0187459 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0179104 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0177934 |
| CAVIN2 | caveolae associated protein 2 | 0.0175591 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0175365 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0169244 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0168407 |
| PLS3 | plastin 3 | 0.0164994 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0164755 |
| TPD52 | tumor protein D52 | 0.0162061 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0160101 |
| MKI67 | marker of proliferation Ki-67 | 0.0159012 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0158521 |
| BRIX1 | BRX1, biogenesis of ribosomes | 0.0156962 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0156409 |
| LAMB1 | laminin, beta 1 | 0.0154065 |
| PDS5A | PDS5 cohesin associated factor A | 0.0152301 |
| USP34 | ubiquitin specific peptidase 34 | 0.0151882 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0148484 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0147973 |
| TPX2 | TPX2, microtubule-associated | 0.014782 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0147178 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0146897 |
| ANXA1 | annexin A1 | 0.0146816 |
| CUL5 | cullin 5 | 0.0146684 |
| PDE8A | phosphodiesterase 8A | 0.0145488 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0145315 |
| SBF2 | SET binding factor 2 | 0.0143681 |
| MYO19 | myosin XIX | 0.0142532 |
| MAP4 | microtubule-associated protein 4 | 0.014223 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0141504 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0138934 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0138338 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0137912 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0137315 |
| XPO1 | exportin 1 | 0.0136887 |
| MTDH | metadherin | 0.0136652 |
| EGFR | epidermal growth factor receptor | 0.0136373 |
| BMP5 | bone morphogenetic protein 5 | 0.0136357 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0135171 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0133925 |
| SRP72 | signal recognition particle 72kDa | 0.0131375 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0130875 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0130489 |
| FIGN | fidgetin | 0.0129032 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0126346 |
| PER1 | period circadian clock 1 | 0.0126134 |
| IL6R | interleukin 6 receptor | 0.0125664 |
| EPGN | epithelial mitogen | 0.0124683 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.33407 |
| FTL | ferritin, light polypeptide | -0.214932 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.14034 |
| TMSB10 | thymosin beta 10 | -0.139444 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.118717 |
| VIM | vimentin | -0.105772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10068 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.099447 |
| RPLP1 | ribosomal protein, large, P1 | -0.0771365 |
| IER3 | immediate early response 3 | -0.0762281 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0760547 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0755149 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0722655 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0705715 |
| RPL23 | ribosomal protein L23 | -0.065924 |
| RPL19 | ribosomal protein L19 | -0.0604717 |
| ACTG1 | actin gamma 1 | -0.0553824 |
| CMIP | c-Maf inducing protein | -0.054063 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0534843 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0525039 |
| ASPH | aspartate beta-hydroxylase | -0.049565 |
| RPS19 | ribosomal protein S19 | -0.0481936 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0453352 |
| YBX1 | Y box binding protein 1 | -0.0430783 |
| PFN1 | profilin 1 | -0.0418678 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0405693 |
| FMNL2 | formin-like 2 | -0.0404443 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0377339 |
| PKM | pyruvate kinase, muscle | -0.0377317 |
| RPS12 | ribosomal protein S12 | -0.0371542 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0365713 |
| S100A6 | S100 calcium binding protein A6 | -0.0362897 |
| RPS8 | ribosomal protein S8 | -0.036158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0359382 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0355881 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0354529 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0332477 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0331084 |
| HMGA1 | high mobility group AT-hook 1 | -0.0328315 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0319495 |
| RPL35A | ribosomal protein L35a | -0.0318833 |
| RPL31 | ribosomal protein L31 | -0.030499 |
| S100A10 | S100 calcium binding protein A10 | -0.0304553 |
| NAV3 | neuron navigator 3 | -0.0296544 |
| RPS20 | ribosomal protein S20 | -0.029413 |
| RPL11 | ribosomal protein L11 | -0.0288936 |
| EGR1 | early growth response 1 | -0.0288785 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0282748 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0281618 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0281261 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0281015 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0280744 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0279878 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0266712 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262635 |
| RPS17 | ribosomal protein S17 | -0.0262572 |
| IL6 | interleukin 6 | -0.0261905 |
| HLA-B | major histocompatibility complex, class I, B | -0.0261698 |
| MCL1 | myeloid cell leukemia 1 | -0.0259998 |
| TPI1 | triosephosphate isomerase 1 | -0.0259464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0258944 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0255825 |
| RPL36 | ribosomal protein L36 | -0.0254887 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025004 |
| RPL8 | ribosomal protein L8 | -0.0249211 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248853 |
| USP3 | ubiquitin specific peptidase 3 | -0.0248669 |
| RPL26 | ribosomal protein L26 | -0.0247208 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0246029 |
| S100A9 | S100 calcium binding protein A9 | -0.0243641 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243563 |
| POTEF | POTE ankyrin domain family, member F | -0.0242498 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0241526 |
| HLA-A | major histocompatibility complex, class I, A | -0.0240602 |
| FAM107B | family with sequence similarity 107, member B | -0.0240477 |
| RPS15 | ribosomal protein S15 | -0.0237769 |
| PARD3 | par-3 family cell polarity regulator | -0.023668 |
| RPL30 | ribosomal protein L30 | -0.0236275 |
| RPL37A | ribosomal protein L37a | -0.0235938 |
| RPL28 | ribosomal protein L28 | -0.0234283 |
| SERF2 | small EDRK-rich factor 2 | -0.0232532 |
| RPS21 | ribosomal protein S21 | -0.022823 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0227629 |
| RPL34 | ribosomal protein L34 | -0.0224378 |
| PTMA | prothymosin, alpha | -0.0223983 |
| STC2 | stanniocalcin 2 | -0.0223811 |
| RPL12 | ribosomal protein L12 | -0.0223446 |
| TAGLN2 | transgelin 2 | -0.0220578 |
| RPL37 | ribosomal protein L37 | -0.0218944 |
| RPS23 | ribosomal protein S23 | -0.0218255 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0215704 |
| RPS27A | ribosomal protein S27a | -0.021564 |
| PRDX1 | peroxiredoxin 1 | -0.0213505 |
| S100A11 | S100 calcium binding protein A11 | -0.0208243 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0207548 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0206297 |
| RPS16 | ribosomal protein S16 | -0.020613 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.020598 |
| NDRG1 | N-myc downstream regulated 1 | -0.020489 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0203189 |
