| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dexamethasone_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.180665 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.115978 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.101048 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0982101 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0978925 |
| S100P | S100 calcium binding protein P | 0.084623 |
| TOP1 | topoisomerase (DNA) I | 0.0817694 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0817145 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0759849 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.074901 |
| IGF2 | insulin-like growth factor 2 | 0.0746427 |
| TXNRD1 | thioredoxin reductase 1 | 0.0743434 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0728939 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0726409 |
| EFNA5 | ephrin-A5 | 0.0666571 |
| NCKAP1 | NCK-associated protein 1 | 0.0665582 |
| DNER | delta/notch-like EGF repeat containing | 0.0652939 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0632762 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0620562 |
| DSPP | dentin sialophosphoprotein | 0.0618198 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0612523 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0603434 |
| FNDC3B | fibronectin type III domain containing 3B | 0.059081 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0589296 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0584011 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0577873 |
| SLTM | SAFB-like, transcription modulator | 0.0559458 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0547585 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0543352 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0543183 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0541206 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0540247 |
| LMO7 | LIM domain 7 | 0.052694 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.052321 |
| S100A9 | S100 calcium binding protein A9 | 0.0518454 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0513442 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0512504 |
| DTNA | dystrobrevin, alpha | 0.0502897 |
| HOMER2 | homer scaffolding protein 2 | 0.0485814 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0485254 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0482684 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0478304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.047384 |
| CCNY | cyclin Y | 0.0473612 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0469817 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0465451 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0463218 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0461797 |
| KRT6A | keratin 6A, type II | 0.0460981 |
| USP3 | ubiquitin specific peptidase 3 | 0.0460518 |
| RNF145 | ring finger protein 145 | 0.0457725 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0455359 |
| IRS2 | insulin receptor substrate 2 | 0.044484 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0437713 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0437706 |
| VIRMA | vir like m6A methyltransferase associated | 0.0433484 |
| HELZ | helicase with zinc finger | 0.0427851 |
| MEF2A | myocyte enhancer factor 2A | 0.0421409 |
| FAM13A | family with sequence similarity 13, member A | 0.0412655 |
| RIOK3 | RIO kinase 3 | 0.0411305 |
| CENPF | centromere protein F, 350/400kDa | 0.0408945 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0406774 |
| YY1AP1 | YY1 associated protein 1 | 0.039907 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0396703 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0390202 |
| LAMB3 | laminin, beta 3 | 0.0389997 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0389728 |
| TMEM165 | transmembrane protein 165 | 0.0383388 |
| TXNIP | thioredoxin interacting protein | 0.0382868 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0382114 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0375258 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0374269 |
| TES | testin LIM domain protein | 0.0372266 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0371661 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0371517 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0370897 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0366988 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0365731 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0356976 |
| ATXN1 | ataxin 1 | 0.0356461 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0352517 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0352409 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0350721 |
| USP47 | ubiquitin specific peptidase 47 | 0.0346989 |
| CD109 | CD109 molecule | 0.0345288 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0340527 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0339661 |
| WDR45B | WD repeat domain 45B | 0.033556 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0334276 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0329732 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0325265 |
| RYBP | RING1 and YY1 binding protein | 0.032349 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.032325 |
| RLF | rearranged L-myc fusion | 0.0319712 |
| SIK3 | SIK family kinase 3 | 0.0315878 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0314808 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0312781 |
| SPAG9 | sperm associated antigen 9 | 0.0311267 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0309984 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0307968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.186867 |
| PTMA | prothymosin, alpha | -0.110913 |
| VIM | vimentin | -0.084362 |
| RPL26 | ribosomal protein L26 | -0.0790771 |
| RPLP1 | ribosomal protein, large, P1 | -0.078062 |
| UBC | ubiquitin C | -0.0773862 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0745626 |
| ASPH | aspartate beta-hydroxylase | -0.0730778 |
| IER3 | immediate early response 3 | -0.072961 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0652749 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0625369 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0616324 |
| VMP1 | vacuole membrane protein 1 | -0.0597371 |
| ENO1 | enolase 1, (alpha) | -0.05733 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0569089 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0536738 |
| JUN | jun proto-oncogene | -0.0517104 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0510948 |
| RPS8 | ribosomal protein S8 | -0.0504485 |
| SQSTM1 | sequestosome 1 | -0.0504064 |
| MCL1 | myeloid cell leukemia 1 | -0.0499826 |
| CD2AP | CD2-associated protein | -0.0498655 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -0.0485224 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0466577 |
| SMAD3 | SMAD family member 3 | -0.0455014 |
| SYT1 | synaptotagmin I | -0.0454899 |
| B2M | beta-2-microglobulin | -0.0437086 |
| RPL37A | ribosomal protein L37a | -0.0432318 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0431988 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0430909 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0429553 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0418912 |
| RNF213 | ring finger protein 213 | -0.0408193 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0398863 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0393047 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0391064 |
| CANX | calnexin | -0.0382037 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0377895 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0377416 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0374794 |
| STK4 | serine/threonine kinase 4 | -0.0372761 |
| RPL35A | ribosomal protein L35a | -0.0371423 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0369857 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0366433 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0365467 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0362377 |
| ANXA2 | annexin A2 | -0.0361301 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0360924 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0359226 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0359101 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0356692 |
| FNIP1 | folliculin interacting protein 1 | -0.0355108 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.035289 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0352849 |
| TOX | thymocyte selection-associated high mobility group box | -0.0350781 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0342629 |
| MATR3 | matrin 3 | -0.0341919 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0339291 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0338033 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0336979 |
| SEPTIN2 | septin 2 | -0.0336359 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0333964 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0329922 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0329776 |
| PNN | pinin, desmosome associated protein | -0.032977 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.032948 |
| CALR | calreticulin | -0.0327906 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0326443 |
| FUS | FUS RNA binding protein | -0.0324021 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0323159 |
| AHNAK | AHNAK nucleoprotein | -0.0321307 |
| NDRG1 | N-myc downstream regulated 1 | -0.0321207 |
| H3-3B | H3.3 histone B | -0.0320293 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0318623 |
| GPATCH2L | G patch domain containing 2-like | -0.0317655 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0316707 |
| GPC6 | glypican 6 | -0.0316657 |
| TBC1D22A | TBC1 domain family, member 22A | -0.031633 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0316105 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0314532 |
| ARRDC3 | arrestin domain containing 3 | -0.031322 |
| RPL19 | ribosomal protein L19 | -0.0312628 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0309414 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0308555 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0307212 |
| RPS4X | ribosomal protein S4, X-linked | -0.0302744 |
| PLEC | plectin | -0.0298831 |
| ACTN4 | actinin, alpha 4 | -0.0297409 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0296264 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0295661 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029435 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.029254 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0289659 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0289449 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0287665 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.028748 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0284718 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0283635 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.028044 |
| FAM107B | family with sequence similarity 107, member B | -0.0279198 |
