| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.288021 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.137361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0958111 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0922123 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0785347 |
| TXNRD1 | thioredoxin reductase 1 | 0.0779968 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0670747 |
| MT2A | metallothionein 2A | 0.0621252 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0575025 |
| RTN4 | reticulon 4 | 0.0479186 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0477828 |
| YBX3 | Y box binding protein 3 | 0.0420521 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0419683 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0395706 |
| RPS8 | ribosomal protein S8 | 0.0380069 |
| ENO1 | enolase 1, (alpha) | 0.0378207 |
| RPS3 | ribosomal protein S3 | 0.0361483 |
| RPS6 | ribosomal protein S6 | 0.0352927 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.034145 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0315401 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0315143 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0308796 |
| VIM | vimentin | 0.0300352 |
| RPL12 | ribosomal protein L12 | 0.0296396 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0295433 |
| IPO7 | importin 7 | 0.0288786 |
| RPS12 | ribosomal protein S12 | 0.0287455 |
| TPM3 | tropomyosin 3 | 0.0280649 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0256791 |
| YBX1 | Y box binding protein 1 | 0.0254477 |
| LDHB | lactate dehydrogenase B | 0.0253675 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0247767 |
| XPOT | exportin, tRNA | 0.0244294 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0243768 |
| MKI67 | marker of proliferation Ki-67 | 0.0243721 |
| RPL35A | ribosomal protein L35a | 0.0241898 |
| PGK1 | phosphoglycerate kinase 1 | 0.0241753 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0237076 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0234538 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0233857 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.022952 |
| RPS19 | ribosomal protein S19 | 0.0226399 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0222676 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0218015 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0215454 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0215051 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0211282 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0206662 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0203565 |
| RPL5 | ribosomal protein L5 | 0.0202972 |
| RPLP1 | ribosomal protein, large, P1 | 0.0200954 |
| POTEF | POTE ankyrin domain family, member F | 0.0192797 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0188807 |
| RPL26 | ribosomal protein L26 | 0.0184239 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0183815 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.018334 |
| TMEM41B | transmembrane protein 41B | 0.018258 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0181931 |
| RPL8 | ribosomal protein L8 | 0.0179903 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0179869 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0178283 |
| MYPN | myopalladin | 0.017787 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0175331 |
| RPS27 | ribosomal protein S27 | 0.0174609 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0172481 |
| RPS15 | ribosomal protein S15 | 0.0171419 |
| RPL37A | ribosomal protein L37a | 0.0171034 |
| PFDN2 | prefoldin subunit 2 | 0.0166045 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0162397 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0161999 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0161022 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0159706 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0159021 |
| SET | SET nuclear proto-oncogene | 0.0157299 |
| RPLP2 | ribosomal protein, large, P2 | 0.0157298 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0156187 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0155588 |
| KIF5B | kinesin family member 5B | 0.0155153 |
| RPL27 | ribosomal protein L27 | 0.0150341 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0148759 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0146341 |
| ARL13B | ADP-ribosylation factor-like 13B | 0.0145428 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0144278 |
| RPS4X | ribosomal protein S4, X-linked | 0.0142894 |
| RPL9 | ribosomal protein L9 | 0.0142745 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0142644 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0142301 |
| ACTG1 | actin gamma 1 | 0.0140141 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0140062 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0139391 |
| RPL37 | ribosomal protein L37 | 0.0138848 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0137293 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0137259 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.013661 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0136342 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0136333 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0135257 |
| TPI1 | triosephosphate isomerase 1 | 0.0134836 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0134821 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0134473 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0993363 |
| RAD51B | RAD51 paralog B | -0.0813141 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0694874 |
| SMAD3 | SMAD family member 3 | -0.0688295 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.068436 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0673083 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0657263 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0625566 |
| EXOC4 | exocyst complex component 4 | -0.0593489 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0576468 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0537902 |
| ATXN1 | ataxin 1 | -0.0502175 |
| FNDC3B | fibronectin type III domain containing 3B | -0.049756 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.049174 |
| ADAR | adenosine deaminase, RNA-specific | -0.0490266 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.047667 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.045917 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0457135 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0455418 |
| RNF213 | ring finger protein 213 | -0.0452748 |
| VCL | vinculin | -0.0444748 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.043931 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0436081 |
| OSMR | oncostatin M receptor | -0.0435817 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0416051 |
| NF1 | neurofibromin 1 | -0.0408172 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0406211 |
| FMNL2 | formin-like 2 | -0.0403849 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0400462 |
| AHNAK | AHNAK nucleoprotein | -0.0400192 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0392842 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0376854 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0374867 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0370732 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0366314 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0361218 |
| EGFR | epidermal growth factor receptor | -0.0359798 |
| SMYD3 | SET and MYND domain containing 3 | -0.0356884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0356139 |
| PYGL | phosphorylase, glycogen, liver | -0.0353346 |
| RIGI | RNA sensor RIG-I | -0.0351856 |
| CDK17 | cyclin-dependent kinase 17 | -0.0351505 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0348533 |
| PRKCE | protein kinase C, epsilon | -0.0344144 |
| NABP1 | nucleic acid binding protein 1 | -0.0343572 |
| ETV6 | ets variant 6 | -0.0343112 |
| EHBP1 | EH domain binding protein 1 | -0.0341806 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0333626 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0332394 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0332136 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0332016 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0331546 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.032579 |
| RYR3 | ryanodine receptor 3 | -0.0324384 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0321436 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0315963 |
| CUX1 | cut-like homeobox 1 | -0.0315406 |
| PTK2 | protein tyrosine kinase 2 | -0.0314481 |
| APP | amyloid beta (A4) precursor protein | -0.0310508 |
| ACTN1 | actinin, alpha 1 | -0.0309701 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0307579 |
| ATG7 | autophagy related 7 | -0.0307045 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0305962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0305787 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0303564 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0297592 |
| HMGA2 | high mobility group AT-hook 2 | -0.0294821 |
| AEBP2 | AE binding protein 2 | -0.0290847 |
| DENND5B | DENN/MADD domain containing 5B | -0.0285085 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0283674 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0281815 |
| FBXO11 | F-box protein 11 | -0.0280772 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0280535 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0279278 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.027778 |
| PLSCR1 | phospholipid scramblase 1 | -0.027737 |
| BBX | bobby sox homolog (Drosophila) | -0.0277111 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027457 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.027325 |
| THOC2 | THO complex 2 | -0.0272628 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0271363 |
| NBEAL1 | neurobeachin-like 1 | -0.0265835 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0264858 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0262721 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0259876 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0259659 |
| YAP1 | Yes-associated protein 1 | -0.0256081 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0254208 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0252691 |
| PHF21A | PHD finger protein 21A | -0.0252026 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0251345 |
| CALD1 | caldesmon 1 | -0.0250723 |
| PMP22 | peripheral myelin protein 22 | -0.0250391 |
| GPATCH2L | G patch domain containing 2-like | -0.0249886 |
| CDK13 | cyclin-dependent kinase 13 | -0.024878 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0247247 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.024686 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0245341 |
| MTA3 | metastasis associated 1 family, member 3 | -0.0244799 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0244571 |
