| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.2239 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.13696 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.12747 |
| TOP1 | topoisomerase (DNA) I | 0.124433 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0904402 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0827415 |
| IL6ST | interleukin 6 signal transducer | 0.0815469 |
| UBC | ubiquitin C | 0.0772409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0732033 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0718358 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0709231 |
| HOMER2 | homer scaffolding protein 2 | 0.0684086 |
| FCHO2 | FCH domain only 2 | 0.067653 |
| FKBP5 | FK506 binding protein 5 | 0.0652501 |
| AREG | amphiregulin | 0.0648986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0615922 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0615325 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0600678 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0594097 |
| S100A6 | S100 calcium binding protein A6 | 0.0577237 |
| AHNAK | AHNAK nucleoprotein | 0.0564537 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0562678 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0560519 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.055519 |
| KRT8 | keratin 8, type II | 0.054003 |
| ANXA2 | annexin A2 | 0.0513524 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0513303 |
| KLF6 | Kruppel-like factor 6 | 0.0511019 |
| EREG | epiregulin | 0.0509614 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0501727 |
| KRT18 | keratin 18, type I | 0.0484614 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0473836 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0464259 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0461824 |
| ACTG1 | actin gamma 1 | 0.0461659 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0449686 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0439653 |
| OGA | O-GlcNAcase | 0.0424804 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0424654 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0424569 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0422557 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0422537 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0421022 |
| FN1 | fibronectin 1 | 0.0418987 |
| KRT7 | keratin 7, type II | 0.0413166 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0412657 |
| RNF145 | ring finger protein 145 | 0.0399396 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0398744 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0390375 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0385297 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0357917 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0357348 |
| NCKAP1 | NCK-associated protein 1 | 0.034568 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0336348 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0334769 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.033199 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0329338 |
| CCNI | cyclin I | 0.0323939 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0315369 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0300952 |
| RDX | radixin | 0.0299466 |
| MT1E | metallothionein 1E | 0.0297441 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0296688 |
| CTSB | cathepsin B | 0.029548 |
| JAK1 | Janus kinase 1 | 0.0291725 |
| TAOK3 | TAO kinase 3 | 0.0291342 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0290714 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0289064 |
| LTA4H | leukotriene A4 hydrolase | 0.0288603 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0287325 |
| DSTN | destrin (actin depolymerizing factor) | 0.0278791 |
| MT1X | metallothionein 1X | 0.0275779 |
| IRS2 | insulin receptor substrate 2 | 0.0274376 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0272753 |
| S100A10 | S100 calcium binding protein A10 | 0.0264106 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0263131 |
| RBM25 | RNA binding motif protein 25 | 0.0262444 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0261386 |
| FLNB | filamin B, beta | 0.0259671 |
| HPCAL1 | hippocalcin-like 1 | 0.0255257 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0250551 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0250394 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0248953 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0247425 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.024683 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0245449 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0245124 |
| TNPO1 | transportin 1 | 0.0243806 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0241175 |
| CLINT1 | clathrin interactor 1 | 0.024106 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0238072 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0236553 |
| DUSP6 | dual specificity phosphatase 6 | 0.0236266 |
| SEPTIN7 | septin 7 | 0.0233784 |
| MAP4 | microtubule-associated protein 4 | 0.0232047 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0231516 |
| CCDC6 | coiled-coil domain containing 6 | 0.0229173 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0229008 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0224941 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0224801 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.203893 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.199092 |
| GRB10 | growth factor receptor-bound protein 10 | -0.178589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.132001 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.110415 |
| FNDC3B | fibronectin type III domain containing 3B | -0.108268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10796 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0992152 |
| FTL | ferritin, light polypeptide | -0.088854 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.07837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0734923 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0728158 |
| DTNA | dystrobrevin, alpha | -0.0726998 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0674795 |
| FAM13A | family with sequence similarity 13, member A | -0.0662161 |
| LMO7 | LIM domain 7 | -0.066151 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0647415 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0638136 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0611295 |
| DUSP10 | dual specificity phosphatase 10 | -0.0599169 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0588382 |
| PTK2 | protein tyrosine kinase 2 | -0.0576808 |
| FAM3C | family with sequence similarity 3, member C | -0.0573887 |
| FBXO32 | F-box protein 32 | -0.0556614 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0543972 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0536464 |
| PTMA | prothymosin, alpha | -0.0534679 |
| ASPH | aspartate beta-hydroxylase | -0.0508753 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0507697 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0500349 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0467731 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0467675 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0466185 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0460942 |
| LAMC2 | laminin, gamma 2 | -0.0455029 |
| MYO5B | myosin VB | -0.0447991 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0446929 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0440741 |
| ARRDC3 | arrestin domain containing 3 | -0.0438323 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0434158 |
| MXD1 | MAX dimerization protein 1 | -0.0430087 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0423481 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0420745 |
| CD2AP | CD2-associated protein | -0.0420542 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0411702 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0411474 |
| MSI2 | musashi RNA-binding protein 2 | -0.0407965 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0393657 |
| NAV2 | neuron navigator 2 | -0.0389995 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0383243 |
| ZNF292 | zinc finger protein 292 | -0.0382772 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0378972 |
| PGK1 | phosphoglycerate kinase 1 | -0.0377784 |
| SQSTM1 | sequestosome 1 | -0.0376968 |
| PKM | pyruvate kinase, muscle | -0.0375583 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0373972 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0372132 |
| FAM162A | family with sequence similarity 162, member A | -0.0370135 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0369317 |
| HLA-A | major histocompatibility complex, class I, A | -0.0363263 |
| PLAU | plasminogen activator, urokinase | -0.0361689 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.036148 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.036038 |
| CD47 | CD47 molecule | -0.0360097 |
| VEGFA | vascular endothelial growth factor A | -0.0359744 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0357155 |
| HMGA1 | high mobility group AT-hook 1 | -0.035193 |
| G0S2 | G0/G1 switch 2 | -0.0351213 |
| FOSL1 | FOS-like antigen 1 | -0.035011 |
| CD109 | CD109 molecule | -0.0342544 |
| HLA-B | major histocompatibility complex, class I, B | -0.0337847 |
| CLDN4 | claudin 4 | -0.0337644 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.033629 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0334752 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0330241 |
| SMAD3 | SMAD family member 3 | -0.0328994 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0320966 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0319262 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0318587 |
| PLSCR1 | phospholipid scramblase 1 | -0.0318578 |
| CSTB | cystatin B (stefin B) | -0.0317326 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0313537 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309819 |
| FAM107B | family with sequence similarity 107, member B | -0.0306578 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0306465 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0305282 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0304027 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.030189 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0300441 |
| RNF213 | ring finger protein 213 | -0.0299415 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.0299151 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0295657 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.029515 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0294684 |
| RBM47 | RNA binding motif protein 47 | -0.0294575 |
| CCNL1 | cyclin L1 | -0.0293783 |
| CD44 | CD44 molecule (Indian blood group) | -0.0292438 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0291874 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0288985 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0288352 |
