| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.34408 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.184429 |
| GDA | guanine deaminase | 0.176359 |
| SRGN | serglycin | 0.148956 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.137506 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.126692 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0791557 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0689138 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0668201 |
| PHF20 | PHD finger protein 20 | 0.0631599 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0626155 |
| DNER | delta/notch-like EGF repeat containing | 0.0604398 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0601002 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0580297 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0513418 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0484565 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0462974 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0462616 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0461336 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.044926 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0443789 |
| RGS2 | regulator of G-protein signaling 2 | 0.0439206 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0431156 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0426892 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0415096 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0408175 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0392541 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0382683 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0378236 |
| DST | dystonin | 0.0370512 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0368981 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0357835 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0355829 |
| SMYD3 | SET and MYND domain containing 3 | 0.0348216 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0339556 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0336509 |
| TXNIP | thioredoxin interacting protein | 0.0335259 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0335199 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0335179 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0334263 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0322819 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0322741 |
| TOP1 | topoisomerase (DNA) I | 0.0307986 |
| NFIA | nuclear factor I/A | 0.0307438 |
| CHML | choroideremia-like (Rab escort protein 2) | 0.030214 |
| KYNU | kynureninase | 0.0294645 |
| CHL1 | cell adhesion molecule L1-like | 0.0292287 |
| ENAH | enabled homolog (Drosophila) | 0.0287225 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0281644 |
| ZFHX3 | zinc finger homeobox 3 | 0.027733 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0273893 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0272877 |
| TXNRD1 | thioredoxin reductase 1 | 0.0271899 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0270678 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0270073 |
| ENO1 | enolase 1, (alpha) | 0.0267997 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0265757 |
| RBM39 | RNA binding motif protein 39 | 0.0261502 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0258864 |
| MT2A | metallothionein 2A | 0.0256889 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0251861 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0251381 |
| MFF | mitochondrial fission factor | 0.0249278 |
| SAMD8 | sterile alpha motif domain containing 8 | 0.0248728 |
| HEATR1 | HEAT repeat containing 1 | 0.024657 |
| FKBP5 | FK506 binding protein 5 | 0.0244282 |
| PRKD3 | protein kinase D3 | 0.0241622 |
| CAVIN2 | caveolae associated protein 2 | 0.0240105 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0239307 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0237625 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0237358 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0236511 |
| LDHA | lactate dehydrogenase A | 0.0230282 |
| OPN3 | opsin 3 | 0.0230069 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0229005 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0228439 |
| IRS2 | insulin receptor substrate 2 | 0.0223081 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0218909 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0218055 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0216739 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0216465 |
| SDC2 | syndecan 2 | 0.0215571 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0211567 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0210151 |
| PDE10A | phosphodiesterase 10A | 0.0207129 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.020625 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0202033 |
| ANXA1 | annexin A1 | 0.0198856 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0198009 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0197415 |
| VCL | vinculin | 0.0196654 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0192614 |
| RTN1 | reticulon 1 | 0.0190373 |
| MT1X | metallothionein 1X | 0.0190304 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0189547 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0188636 |
| INTS6 | integrator complex subunit 6 | 0.0186267 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0182318 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.0182249 |
| KLF9 | Kruppel-like factor 9 | 0.0181636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.190256 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.161538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145062 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0955743 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.093931 |
| CDH13 | cadherin 13 | -0.0925828 |
| ASPH | aspartate beta-hydroxylase | -0.0857973 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0805862 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0789781 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0740809 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0738437 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0698414 |
| FN1 | fibronectin 1 | -0.0685343 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0652349 |
| MAP7 | microtubule-associated protein 7 | -0.0565514 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0552975 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0544026 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0523099 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0518321 |
| RPLP1 | ribosomal protein, large, P1 | -0.0496664 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0480746 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0470771 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0461012 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0455732 |
| VIM | vimentin | -0.0454593 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.045236 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0432574 |
| FTL | ferritin, light polypeptide | -0.0418263 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0411761 |
| CD44 | CD44 molecule (Indian blood group) | -0.0401804 |
| INHBA | inhibin, beta A | -0.0400623 |
| MYOF | myoferlin | -0.0399891 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0381421 |
| COL5A2 | collagen, type V, alpha 2 | -0.0379314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.037848 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0372223 |
| NBEAL1 | neurobeachin-like 1 | -0.0367194 |
| SPAG9 | sperm associated antigen 9 | -0.0363925 |
| LSAMP | limbic system-associated membrane protein | -0.0360693 |
| SQSTM1 | sequestosome 1 | -0.0349927 |
| NDRG1 | N-myc downstream regulated 1 | -0.0348933 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0344128 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0338006 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324771 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0322485 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.032081 |
| FMNL2 | formin-like 2 | -0.0320449 |
| NCKAP5 | NCK-associated protein 5 | -0.0320352 |
| CTBP2 | C-terminal binding protein 2 | -0.0305967 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.030213 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0297795 |
| IER3 | immediate early response 3 | -0.0290487 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0288016 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0287555 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0286233 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0274215 |
| BMERB1 | bMERB domain containing 1 | -0.0274066 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0273131 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0271543 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0270023 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0268996 |
| PALLD | palladin, cytoskeletal associated protein | -0.0265387 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0263564 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0261128 |
| RPL35A | ribosomal protein L35a | -0.0259569 |
| MAP1B | microtubule-associated protein 1B | -0.0258388 |
| S100A6 | S100 calcium binding protein A6 | -0.0256838 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0255772 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0255469 |
| GRAMD1B | GRAM domain containing 1B | -0.0255324 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0252842 |
| EZR | ezrin | -0.0251816 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0250989 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250363 |
| GLIS3 | GLIS family zinc finger 3 | -0.0244116 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0233908 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0231942 |
| MYO10 | myosin X | -0.0228694 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0228119 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0228109 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0228025 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.022605 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0224895 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0221904 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0220008 |
| HLA-A | major histocompatibility complex, class I, A | -0.0218472 |
| CTSL | cathepsin L | -0.0218182 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0217569 |
| RIGI | RNA sensor RIG-I | -0.0217128 |
| RPL26 | ribosomal protein L26 | -0.0214859 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0213311 |
| PTMA | prothymosin, alpha | -0.0213188 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0212635 |
| XYLT1 | xylosyltransferase I | -0.0211992 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0210253 |
| RPL13A | ribosomal protein L13a | -0.020834 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0205648 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0205297 |
| PDE7B | phosphodiesterase 7B | -0.0205079 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0204807 |
