| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.12695 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.102589 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0854796 |
| FKBP5 | FK506 binding protein 5 | 0.0801433 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0775919 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0750196 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0736963 |
| PLPP1 | phospholipid phosphatase 1 | 0.0721456 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0709037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0708407 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0675 |
| ENO1 | enolase 1, (alpha) | 0.0654799 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0642564 |
| VIM | vimentin | 0.0635599 |
| RPS6 | ribosomal protein S6 | 0.0593209 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0552589 |
| GNAS | GNAS complex locus | 0.0530261 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.050576 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0493217 |
| H1-0 | H1.0 linker histone | 0.0487007 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0476095 |
| OGA | O-GlcNAcase | 0.0458688 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0454926 |
| PHIP | pleckstrin homology domain interacting protein | 0.0442569 |
| RPS5 | ribosomal protein S5 | 0.0442305 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0440399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.043909 |
| WASF2 | WAS protein family, member 2 | 0.043338 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0433222 |
| PTMA | prothymosin, alpha | 0.0417317 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0407643 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0404352 |
| SET | SET nuclear proto-oncogene | 0.040373 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.040083 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0399762 |
| RPS12 | ribosomal protein S12 | 0.0399494 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0395834 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0391621 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0386542 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0383491 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0381948 |
| RPS16 | ribosomal protein S16 | 0.0381611 |
| TPX2 | TPX2, microtubule-associated | 0.0381118 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0376914 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0375788 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0373892 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0373353 |
| EMP1 | epithelial membrane protein 1 | 0.036942 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0366294 |
| RPL7 | ribosomal protein L7 | 0.0365276 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.03641 |
| PCDH9 | protocadherin 9 | 0.0361123 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0359143 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0354724 |
| SEPTIN7 | septin 7 | 0.0348227 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0348152 |
| PCDH7 | protocadherin 7 | 0.0347634 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0344889 |
| RPL36A | ribosomal protein L36a | 0.0343344 |
| RPS8 | ribosomal protein S8 | 0.03422 |
| TENM2 | teneurin transmembrane protein 2 | 0.0339961 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0334031 |
| RPS2 | ribosomal protein S2 | 0.0333868 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0329903 |
| RACK1 | receptor for activated C kinase 1 | 0.0329114 |
| BRDT | bromodomain, testis-specific | 0.0329058 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0329022 |
| PGK1 | phosphoglycerate kinase 1 | 0.0327107 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0325182 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0316043 |
| POU3F2 | POU class 3 homeobox 2 | 0.0312487 |
| ACTG1 | actin gamma 1 | 0.0309869 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0303979 |
| RPLP1 | ribosomal protein, large, P1 | 0.030389 |
| YY1 | YY1 transcription factor | 0.030345 |
| HTATSF1 | HIV-1 Tat specific factor 1 | 0.0302792 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.03023 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0301778 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.030019 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0300167 |
| TPM4 | tropomyosin 4 | 0.0297616 |
| KHSRP | KH-type splicing regulatory protein | 0.0295154 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.029356 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0292534 |
| DSTN | destrin (actin depolymerizing factor) | 0.0289722 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0288855 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0284622 |
| CALR | calreticulin | 0.0283346 |
| RPL36 | ribosomal protein L36 | 0.0283109 |
| TUBA1B | tubulin, alpha 1b | 0.028304 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0282143 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.028099 |
| STAG2 | stromal antigen 2 | 0.0280976 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0280044 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0278512 |
| RPL35A | ribosomal protein L35a | 0.0278188 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0276354 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0273558 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0272936 |
| RPL37 | ribosomal protein L37 | 0.0270924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | -0.101792 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0971558 |
| HDAC9 | histone deacetylase 9 | -0.0895677 |
| COL5A2 | collagen, type V, alpha 2 | -0.0885767 |
| PRKD1 | protein kinase D1 | -0.0635871 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0622925 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0604833 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0596231 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0544545 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0543488 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0536035 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0515218 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0514401 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0502168 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.045428 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0441523 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0434972 |
| NRG1 | neuregulin 1 | -0.0422825 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0413658 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0403705 |
| SMYD3 | SET and MYND domain containing 3 | -0.038387 |
| CADM2 | cell adhesion molecule 2 | -0.0374116 |
| RASAL2 | RAS protein activator like 2 | -0.0364357 |
| APP | amyloid beta (A4) precursor protein | -0.0359172 |
| HMGA2 | high mobility group AT-hook 2 | -0.0355927 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0354129 |
| GSE1 | Gse1 coiled-coil protein | -0.0350532 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0348977 |
| RIGI | RNA sensor RIG-I | -0.0348151 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0347662 |
| MEIS2 | Meis homeobox 2 | -0.0342437 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0338269 |
| WDR26 | WD repeat domain 26 | -0.0336197 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0334241 |
| UBE3A | ubiquitin protein ligase E3A | -0.0331724 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314374 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0312396 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0311008 |
| FNIP1 | folliculin interacting protein 1 | -0.0309844 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0309484 |
| CRY1 | cryptochrome circadian clock 1 | -0.030753 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0306457 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0303406 |
| FOXP2 | forkhead box P2 | -0.0301999 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0299473 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0297612 |
| PDGFC | platelet derived growth factor C | -0.02962 |
| ATXN1 | ataxin 1 | -0.0296025 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0294842 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0293711 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0293181 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0292801 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0288492 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0284475 |
| SUCO | SUN domain containing ossification factor | -0.0281889 |
| TFRC | transferrin receptor | -0.0278435 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0278078 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0277001 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0269634 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0267852 |
| TAPBP | TAP binding protein (tapasin) | -0.0265628 |
| FOXK1 | forkhead box K1 | -0.0261936 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0261516 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.025891 |
| FBXO11 | F-box protein 11 | -0.0258384 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0258359 |
| USP25 | ubiquitin specific peptidase 25 | -0.0258219 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0257849 |
| CCDC138 | coiled-coil domain containing 138 | -0.0253887 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0253027 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0250824 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.024984 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0249374 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0249328 |
| AEBP2 | AE binding protein 2 | -0.0248231 |
| TGFB2 | transforming growth factor, beta 2 | -0.0247228 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0246727 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0246298 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | -0.0243606 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0243118 |
| UPP1 | uridine phosphorylase 1 | -0.0242808 |
| SVIL | supervillin | -0.0242611 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.024252 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0242288 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0241915 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0241398 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0240478 |
| ZNF638 | zinc finger protein 638 | -0.0240009 |
| FGF13 | fibroblast growth factor 13 | -0.0239448 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0238887 |
| METAP2 | methionyl aminopeptidase 2 | -0.0237769 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.023775 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0237309 |
| EXOC2 | exocyst complex component 2 | -0.023714 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0235199 |
| DICER1 | dicer 1, ribonuclease type III | -0.0235147 |
| COG6 | component of oligomeric golgi complex 6 | -0.0234745 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0232466 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0231432 |
| IPO7 | importin 7 | -0.0230461 |
