Dexamethasone_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Dexamethasone perturbation in SNU-423 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Dexamethasone_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.219497
ERRFI1 ERBB receptor feedback inhibitor 1 0.199417
NAMPT nicotinamide phosphoribosyltransferase 0.185907
ZMYND8 zinc finger, MYND-type containing 8 0.156251
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.144431
FKBP5 FK506 binding protein 5 0.138582
VIM vimentin 0.130559
FN1 fibronectin 1 0.110429
HMGA2 high mobility group AT-hook 2 0.0727471
SDC4 syndecan 4 0.0714406
STC1 stanniocalcin 1 0.0649595
IL6ST interleukin 6 signal transducer 0.0613489
TOP1 topoisomerase (DNA) I 0.0604981
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0599413
DIAPH2 diaphanous-related formin 2 0.0592961
MT1X metallothionein 1X 0.058771
MT2A metallothionein 2A 0.057877
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0559672
RERE arginine-glutamic acid dipeptide (RE) repeats 0.055122
HIPK2 homeodomain interacting protein kinase 2 0.0540463
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0531355
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0518552
KLF9 Kruppel-like factor 9 0.0517724
CLMP CXADR-like membrane protein 0.0513471
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0498757
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0497963
FBXO32 F-box protein 32 0.0489512
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0488028
LPP LIM domain containing preferred translocation partner in lipoma 0.0445609
HOMER2 homer scaffolding protein 2 0.0444256
ACSL1 acyl-CoA synthetase long-chain family member 1 0.0440592
NAP1L1 nucleosome assembly protein 1-like 1 0.0437482
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0436303
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0433872
TPM4 tropomyosin 4 0.0427392
UTRN utrophin 0.0424489
SAA2-SAA4 SAA2-SAA4 readthrough 0.0416475
ABLIM3 actin binding LIM protein family, member 3 0.0411592
TPT1 tumor protein, translationally-controlled 1 0.041014
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0392272
OSBPL8 oxysterol binding protein-like 8 0.038476
PTPRG protein tyrosine phosphatase, receptor type, G 0.0384035
AHNAK AHNAK nucleoprotein 0.0381731
PTMA prothymosin, alpha 0.0379368
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0377022
PCBP3 poly(rC) binding protein 3 0.0375992
ANKRD28 ankyrin repeat domain 28 0.0364681
TSC22D3 TSC22 domain family, member 3 0.0363145
SAA2 serum amyloid A2 0.036016
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0359687
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0356039
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0355917
MAP4 microtubule-associated protein 4 0.0351457
PRKN parkin RBR E3 ubiquitin protein ligase 0.0349068
CUL4B cullin 4B 0.0348729
ZNF608 zinc finger protein 608 0.0330744
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0330073
ZFAND5 zinc finger, AN1-type domain 5 0.0329293
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0328653
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.0316246
TPR translocated promoter region, nuclear basket protein 0.0315641
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.0308902
BICC1 BicC family RNA binding protein 1 0.030722
ZNF292 zinc finger protein 292 0.0299181
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0297699
EFNA5 ephrin-A5 0.0294867
CDK13 cyclin-dependent kinase 13 0.0293687
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0291901
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0291851
DPYD dihydropyrimidine dehydrogenase 0.0289931
SLC38A1 solute carrier family 38, member 1 0.0287561
ESYT2 extended synaptotagmin-like protein 2 0.0286224
KPNB1 karyopherin (importin) beta 1 0.0278912
PHF21A PHD finger protein 21A 0.027873
RPS6 ribosomal protein S6 0.0276617
MXI1 MAX interactor 1, dimerization protein 0.0275533
ZBTB38 zinc finger and BTB domain containing 38 0.0275137
LDHA lactate dehydrogenase A 0.0273969
DNER delta/notch-like EGF repeat containing 0.027203
JAK1 Janus kinase 1 0.0271943
JAK2 Janus kinase 2 0.0269344
NRP1 neuropilin 1 0.0268741
PLIN2 perilipin 2 0.026856
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0268402
ABHD12 abhydrolase domain containing 12 0.0266511
GDI2 GDP dissociation inhibitor 2 0.0265263
TM9SF3 transmembrane 9 superfamily member 3 0.0263364
HIP1 huntingtin interacting protein 1 0.0262505
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0261185
RPS24 ribosomal protein S24 0.0259776
CDK19 cyclin-dependent kinase 19 0.0255519
FOXP1 forkhead box P1 0.0254917
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0254471
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0245721
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0244393
SKIC3 SKI3 subunit of superkiller complex 0.0244245
DGKH diacylglycerol kinase, eta 0.0244198
ANGPTL4 angiopoietin-like 4 0.0244167
KLHL24 kelch-like family member 24 0.0242931
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0242304

decreased expression

Symbol Name Standardized Value
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.217025
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.164908
FRMD4A FERM domain containing 4A -0.142034
PDE10A phosphodiesterase 10A -0.128776
TRIO trio Rho guanine nucleotide exchange factor -0.122458
CADM1 cell adhesion molecule 1 -0.115187
SMAD3 SMAD family member 3 -0.113219
EXT1 exostosin glycosyltransferase 1 -0.0885284
SOD2 superoxide dismutase 2, mitochondrial -0.0798312
ZMIZ1 zinc finger, MIZ-type containing 1 -0.0796528
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -0.0777728
COL6A3 collagen, type VI, alpha 3 -0.0704166
FTH1 ferritin, heavy polypeptide 1 -0.0654312
PPARD peroxisome proliferator-activated receptor delta -0.0643879
HDAC9 histone deacetylase 9 -0.0614958
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0577777
CD44 CD44 molecule (Indian blood group) -0.0572413
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0572412
VCL vinculin -0.0570097
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0569386
EDIL3 EGF-like repeats and discoidin I-like domains 3 -0.0538017
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0525043
EGR1 early growth response 1 -0.0524051
NABP1 nucleic acid binding protein 1 -0.0522675
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0514462
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0479074
ATXN1 ataxin 1 -0.0468229
DLG1 discs, large homolog 1 (Drosophila) -0.0438237
LOXL2 lysyl oxidase-like 2 -0.040459
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.0397793
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0396123
VEGFA vascular endothelial growth factor A -0.0394042
SYNJ2 synaptojanin 2 -0.0383907
NAV2 neuron navigator 2 -0.0373842
FRMD5 FERM domain containing 5 -0.0373093
RIGI RNA sensor RIG-I -0.0362629
WTAP Wilms tumor 1 associated protein -0.0358532
PCBP2 poly(rC) binding protein 2 -0.0355327
RAI14 retinoic acid induced 14 -0.0353489
PALLD palladin, cytoskeletal associated protein -0.0353139
TNIP1 TNFAIP3 interacting protein 1 -0.0351799
TAPBP TAP binding protein (tapasin) -0.0351539
MSN moesin -0.0350774
EPAS1 endothelial PAS domain protein 1 -0.0342865
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0334799
LOC112694756 uncharaterized LOC112694756 -0.0332779
SHB Src homology 2 domain containing adaptor protein B -0.0331848
AFF4 AF4/FMR2 family, member 4 -0.0326035
PLPP6 phospholipid phosphatase 6 -0.0321379
TENT5A terminal nucleotidyltransferase 5A -0.0314117
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0312601
ATP13A3 ATPase type 13A3 -0.0312418
KIAA1217 KIAA1217 -0.031198
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.0305676
CLIC4 chloride intracellular channel 4 -0.030462
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0303019
BTBD9 BTB (POZ) domain containing 9 -0.0301372
THBS1 thrombospondin 1 -0.0300572
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0298528
COL5A1 collagen, type V, alpha 1 -0.0291393
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0290396
HLA-A major histocompatibility complex, class I, A -0.0287238
IL1RAP interleukin 1 receptor accessory protein -0.0284841
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0283409
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0281835
RB1CC1 RB1-inducible coiled-coil 1 -0.0276143
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0275514
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.0275168
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 -0.0269789
RBM39 RNA binding motif protein 39 -0.0269557
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 -0.0263041
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0254554
KYNU kynureninase -0.0254111
SOX9 SRY (sex determining region Y)-box 9 -0.0252045
SP100 SP100 nuclear antigen -0.0251807
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0249402
SQSTM1 sequestosome 1 -0.0247568
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0246171
NCOA7 nuclear receptor coactivator 7 -0.0244889
VCAN versican -0.0244489
MYH9 myosin, heavy chain 9, non-muscle -0.0242755
NAV1 neuron navigator 1 -0.0242615
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0241652
TSC22D2 TSC22 domain family, member 2 -0.0240041
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0239537
CCNL1 cyclin L1 -0.0239149
MAP1B microtubule-associated protein 1B -0.0235231
COL1A2 collagen, type I, alpha 2 -0.0232847
LRRC7 leucine rich repeat containing 7 -0.0232582
IGFBP7 insulin-like growth factor binding protein 7 -0.0232075
IFITM3 interferon induced transmembrane protein 3 -0.0229948
ZHX2 zinc fingers and homeoboxes 2 -0.0228162
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0227376
MX1 MX dynamin-like GTPase 1 -0.0225896
FAM219A family with sequence similarity 219, member A -0.0224659
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0224245
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0218903
RTN4 reticulon 4 -0.021777
CREB5 cAMP responsive element binding protein 5 -0.0217649
FILIP1L filamin A interacting protein 1-like -0.0216988