| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexamethasone perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexamethasone_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.255398 |
| MT1X | metallothionein 1X | 0.149022 |
| HIP1 | huntingtin interacting protein 1 | 0.148946 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.11191 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102044 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.087455 |
| MT1E | metallothionein 1E | 0.0812983 |
| GLUL | glutamate-ammonia ligase | 0.0700865 |
| FAM13A | family with sequence similarity 13, member A | 0.068281 |
| TOP1 | topoisomerase (DNA) I | 0.0681322 |
| FOXO1 | forkhead box O1 | 0.05943 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0589234 |
| FKBP5 | FK506 binding protein 5 | 0.0542987 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0495081 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0457259 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0454092 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0443709 |
| TXNIP | thioredoxin interacting protein | 0.0430517 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0420346 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0418387 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0391956 |
| DUSP12 | dual specificity phosphatase 12 | 0.0382206 |
| FNIP1 | folliculin interacting protein 1 | 0.037695 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0362811 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0349536 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0348392 |
| PDZD2 | PDZ domain containing 2 | 0.0347381 |
| H3-3B | H3.3 histone B | 0.0333044 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0325155 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0320376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0312715 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.03104 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0310239 |
| EMP1 | epithelial membrane protein 1 | 0.030843 |
| LAMB1 | laminin, beta 1 | 0.0308104 |
| CORO1C | coronin, actin binding protein, 1C | 0.0300332 |
| LOX | lysyl oxidase | 0.030019 |
| STAG2 | stromal antigen 2 | 0.0299767 |
| SRP72 | signal recognition particle 72kDa | 0.0299548 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0292464 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0280847 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0279315 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0277408 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0270369 |
| IL1R1 | interleukin 1 receptor, type I | 0.0270198 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0267209 |
| DCN | decorin | 0.0265564 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0264841 |
| MYOF | myoferlin | 0.0264671 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0262308 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0260242 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255505 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0255244 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0250443 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.0249358 |
| JAK1 | Janus kinase 1 | 0.0249144 |
| CALD1 | caldesmon 1 | 0.0245915 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0242746 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0239738 |
| FOXO3 | forkhead box O3 | 0.0239287 |
| FBXO32 | F-box protein 32 | 0.0237259 |
| ADM | adrenomedullin | 0.0232043 |
| HMGA2 | high mobility group AT-hook 2 | 0.0231954 |
| ZFHX3 | zinc finger homeobox 3 | 0.0231668 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0229997 |
| IL6ST | interleukin 6 signal transducer | 0.0222211 |
| NNMT | nicotinamide N-methyltransferase | 0.0219971 |
| MLEC | malectin | 0.0219195 |
| OGA | O-GlcNAcase | 0.0218393 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0211231 |
| KLF9 | Kruppel-like factor 9 | 0.0211049 |
| ZNF608 | zinc finger protein 608 | 0.0210755 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0210159 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0208467 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0207638 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0206767 |
| SCFD1 | sec1 family domain containing 1 | 0.0206335 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0205825 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0204937 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0204512 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0202223 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0198989 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0198908 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0198795 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0197831 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.019432 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0193563 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0193425 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0193086 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0192926 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0189715 |
| ZNF451 | zinc finger protein 451 | 0.018828 |
| FMNL2 | formin-like 2 | 0.0187873 |
| NAV2 | neuron navigator 2 | 0.0187048 |
| PALLD | palladin, cytoskeletal associated protein | 0.01868 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0186689 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0185969 |
| TMSB4X | thymosin beta 4, X-linked | 0.0185033 |
| COL5A2 | collagen, type V, alpha 2 | 0.0184749 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0184533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.344725 |
| VIM | vimentin | -0.165049 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142095 |
| NDRG1 | N-myc downstream regulated 1 | -0.10067 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0961681 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0835644 |
| CD44 | CD44 molecule (Indian blood group) | -0.0821344 |
| HLA-B | major histocompatibility complex, class I, B | -0.0800239 |
| MAP1B | microtubule-associated protein 1B | -0.0745878 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0745019 |
| IL6 | interleukin 6 | -0.0736356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0713441 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0659551 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0656383 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0642699 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0581376 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0580817 |
| TMSB10 | thymosin beta 10 | -0.0577084 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0567206 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0555704 |
| CADM1 | cell adhesion molecule 1 | -0.0545135 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0529809 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0525353 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0519098 |
| STC1 | stanniocalcin 1 | -0.050091 |
| PRSS23 | protease, serine, 23 | -0.0496374 |
| COL1A1 | collagen, type I, alpha 1 | -0.0493987 |
| LOXL2 | lysyl oxidase-like 2 | -0.0487651 |
| CDH13 | cadherin 13 | -0.0483817 |
| PTMA | prothymosin, alpha | -0.0480204 |
| HLA-C | major histocompatibility complex, class I, C | -0.04618 |
| COL6A3 | collagen, type VI, alpha 3 | -0.045143 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0448956 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0446335 |
| VEGFA | vascular endothelial growth factor A | -0.044006 |
| ASPH | aspartate beta-hydroxylase | -0.0437431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0433095 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0430054 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0420048 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0416 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0415979 |
| CALU | calumenin | -0.0409543 |
| RTN4 | reticulon 4 | -0.0402031 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0391333 |
| RAI14 | retinoic acid induced 14 | -0.0387154 |
| PKM | pyruvate kinase, muscle | -0.0382507 |
| SMAD3 | SMAD family member 3 | -0.0370077 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0364827 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.036073 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0348214 |
| VEGFC | vascular endothelial growth factor C | -0.034755 |
| GLIS3 | GLIS family zinc finger 3 | -0.0346468 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0346034 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0345261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0335905 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0335558 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.033547 |
| COL5A1 | collagen, type V, alpha 1 | -0.0333687 |
| EGFR | epidermal growth factor receptor | -0.0331008 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0330626 |
| FTL | ferritin, light polypeptide | -0.0328143 |
| TPM1 | tropomyosin 1 (alpha) | -0.0318668 |
| MEF2A | myocyte enhancer factor 2A | -0.0309974 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0308781 |
| CDK6 | cyclin-dependent kinase 6 | -0.0305209 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0302995 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0302309 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0299626 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0291012 |
| CALR | calreticulin | -0.0289259 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0288635 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0288486 |
| YBX1 | Y box binding protein 1 | -0.0286516 |
| HDAC9 | histone deacetylase 9 | -0.0285059 |
| S100A10 | S100 calcium binding protein A10 | -0.0284922 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0284431 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0282296 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0277381 |
| COL1A2 | collagen, type I, alpha 2 | -0.0275117 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0272162 |
| NAV1 | neuron navigator 1 | -0.027064 |
| ATP13A3 | ATPase type 13A3 | -0.0269872 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0269765 |
| RPS19 | ribosomal protein S19 | -0.0269276 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0264738 |
| SDC4 | syndecan 4 | -0.0263812 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0259211 |
| SYNJ2 | synaptojanin 2 | -0.0258224 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0254154 |
| SEPTIN9 | septin 9 | -0.0253967 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250789 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.024726 |
| HLA-A | major histocompatibility complex, class I, A | -0.0246333 |
| ECE1 | endothelin converting enzyme 1 | -0.024567 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0240328 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0240089 |
| QKI | QKI, KH domain containing, RNA binding | -0.0239615 |
| GPC6 | glypican 6 | -0.023931 |
| EGR1 | early growth response 1 | -0.0233265 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0232952 |
