Dexamethasone_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Dexamethasone perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Dexamethasone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
BIRC3 baculoviral IAP repeat containing 3 0.185433
MT2A metallothionein 2A 0.146309
TMSB10 thymosin beta 10 0.110445
MBNL1 muscleblind-like splicing regulator 1 0.107626
ZMYND8 zinc finger, MYND-type containing 8 0.1019
TOP2A topoisomerase (DNA) II alpha 170kDa 0.100995
MT1X metallothionein 1X 0.0959094
AKAP12 A kinase (PRKA) anchor protein 12 0.093832
ERRFI1 ERBB receptor feedback inhibitor 1 0.0913266
TXNIP thioredoxin interacting protein 0.0817318
ANKRD28 ankyrin repeat domain 28 0.0749577
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.0747843
FKBP5 FK506 binding protein 5 0.0733219
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0711389
ZBTB38 zinc finger and BTB domain containing 38 0.0572608
TPX2 TPX2, microtubule-associated 0.057223
KLF9 Kruppel-like factor 9 0.0570783
MBNL2 muscleblind-like splicing regulator 2 0.0533713
TOP1 topoisomerase (DNA) I 0.0439221
SRGN serglycin 0.0428366
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0424077
SET SET nuclear proto-oncogene 0.0415695
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.0414154
RBM39 RNA binding motif protein 39 0.0401228
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0394072
TXNRD1 thioredoxin reductase 1 0.0392712
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0390896
MKI67 marker of proliferation Ki-67 0.0388541
ESYT2 extended synaptotagmin-like protein 2 0.0378141
DUSP12 dual specificity phosphatase 12 0.03712
ANXA2 annexin A2 0.036661
NAMPT nicotinamide phosphoribosyltransferase 0.0365625
CKAP5 cytoskeleton associated protein 5 0.0344915
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0343388
ZBTB16 zinc finger and BTB domain containing 16 0.0335427
CAMKMT calmodulin-lysine N-methyltransferase 0.0330666
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0330429
WAC WW domain containing adaptor with coiled-coil 0.0329317
PTPRG protein tyrosine phosphatase, receptor type, G 0.03257
PRPF8 pre-mRNA processing factor 8 0.0324736
CREBRF CREB3 regulatory factor 0.0322112
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.031803
YAP1 Yes-associated protein 1 0.0311607
EFNA5 ephrin-A5 0.0304152
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.030069
EIF5B eukaryotic translation initiation factor 5B 0.0295809
BASP1 brain abundant, membrane attached signal protein 1 0.0291191
NCOR1 nuclear receptor corepressor 1 0.0281321
KIF5B kinesin family member 5B 0.0281049
DIAPH3 diaphanous-related formin 3 0.0279975
SMC4 structural maintenance of chromosomes 4 0.0277842
RPL23 ribosomal protein L23 0.0273729
MYOF myoferlin 0.0270891
PHF20 PHD finger protein 20 0.0269659
UBC ubiquitin C 0.026817
DPYD dihydropyrimidine dehydrogenase 0.0266154
RFC3 replication factor C (activator 1) 3, 38kDa 0.0266124
NAP1L1 nucleosome assembly protein 1-like 1 0.0260589
PDE4D phosphodiesterase 4D, cAMP-specific 0.0258732
RPS3 ribosomal protein S3 0.0256932
ZNF609 zinc finger protein 609 0.0254542
CDC42SE2 CDC42 small effector 2 0.0253164
LMBR1 limb development membrane protein 1 0.0251167
KLF6 Kruppel-like factor 6 0.0244789
RSRC1 arginine/serine-rich coiled-coil 1 0.0243622
TTK TTK protein kinase 0.0243449
TNPO1 transportin 1 0.0242552
RSF1 remodeling and spacing factor 1 0.024241
LATS2 large tumor suppressor kinase 2 0.0238583
ALCAM activated leukocyte cell adhesion molecule 0.0238214
FMNL2 formin-like 2 0.0237139
CKAP2 cytoskeleton associated protein 2 0.0237115
MAP2K1 mitogen-activated protein kinase kinase 1 0.0237043
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0236448
EEF2 eukaryotic translation elongation factor 2 0.0235735
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0234276
AKAP13 A kinase (PRKA) anchor protein 13 0.023101
MIS18BP1 MIS18 binding protein 1 0.0230853
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0230336
PUM2 pumilio RNA-binding family member 2 0.0230066
HSPA4 heat shock 70kDa protein 4 0.0226705
TSC22D3 TSC22 domain family, member 3 0.0225132
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0224945
RDX radixin 0.0224735
BRD8 bromodomain containing 8 0.0224718
PNISR PNN-interacting serine/arginine-rich protein 0.0223078
ZC3H13 zinc finger CCCH-type containing 13 0.0222958
NIPBL Nipped-B homolog (Drosophila) 0.0222413
NKTR natural killer cell triggering receptor 0.0221305
AHCTF1 AT hook containing transcription factor 1 0.0221257
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0220557
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0217986
ZFHX3 zinc finger homeobox 3 0.021678
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0216294
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.021477
KIAA1328 KIAA1328 0.0208494
KPNB1 karyopherin (importin) beta 1 0.0207872
TBC1D5 TBC1 domain family, member 5 0.0204677
CCNH cyclin H 0.0204102
CENPF centromere protein F, 350/400kDa 0.0203362

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.220366
IGFBP3 insulin-like growth factor binding protein 3 -0.156541
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.121465
FNDC3B fibronectin type III domain containing 3B -0.108069
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0942635
CD44 CD44 molecule (Indian blood group) -0.0915147
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0894495
NDRG1 N-myc downstream regulated 1 -0.0819294
HILPDA hypoxia inducible lipid droplet-associated -0.0769384
VIM vimentin -0.0709405
SMAD3 SMAD family member 3 -0.0686394
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0683874
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0637252
ATXN1 ataxin 1 -0.062783
PTMA prothymosin, alpha -0.0622339
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0549885
ASPH aspartate beta-hydroxylase -0.0525826
LDHA lactate dehydrogenase A -0.0521979
TRIO trio Rho guanine nucleotide exchange factor -0.0521617
DTNA dystrobrevin, alpha -0.0519518
NT5E 5'-nucleotidase, ecto (CD73) -0.0509153
MACF1 microtubule-actin crosslinking factor 1 -0.0503187
IER3 immediate early response 3 -0.0499962
FLNB filamin B, beta -0.0496734
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0493121
PKM pyruvate kinase, muscle -0.0488988
SAMD4A sterile alpha motif domain containing 4A -0.048198
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.043368
BHLHE40 basic helix-loop-helix family, member e40 -0.0433664
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0421981
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0418792
EGR1 early growth response 1 -0.0408051
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0407577
RIGI RNA sensor RIG-I -0.039175
ANKRD37 ankyrin repeat domain 37 -0.0391155
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0390461
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0380639
BTG1 B-cell translocation gene 1, anti-proliferative -0.0379768
LOC112694756 uncharaterized LOC112694756 -0.0377531
FN1 fibronectin 1 -0.0372363
PTK2 protein tyrosine kinase 2 -0.0366642
DGKD diacylglycerol kinase, delta 130kDa -0.0365814
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0361703
PRKCA protein kinase C, alpha -0.0361183
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0361018
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.036072
EGFR epidermal growth factor receptor -0.0355048
SQSTM1 sequestosome 1 -0.0354432
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0354043
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0352966
FMN1 formin 1 -0.0346322
NAV3 neuron navigator 3 -0.0341853
HOOK2 hook microtubule-tethering protein 2 -0.0336934
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.033642
OSMR oncostatin M receptor -0.0335349
CAPRIN2 caprin family member 2 -0.0333774
NAV2 neuron navigator 2 -0.0330234
NCEH1 neutral cholesterol ester hydrolase 1 -0.0329303
PDGFA platelet-derived growth factor alpha polypeptide -0.0327846
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0327002
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0325501
PBX3 pre-B-cell leukemia homeobox 3 -0.0323386
SDC4 syndecan 4 -0.0321462
WSB1 WD repeat and SOCS box containing 1 -0.0320658
RAD51B RAD51 paralog B -0.0319647
DSCAM Down syndrome cell adhesion molecule -0.0319256
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0318393
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.031225
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0312043
NGLY1 N-glycanase 1 -0.0305914
ATP13A3 ATPase type 13A3 -0.0304507
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0303627
SPAG9 sperm associated antigen 9 -0.0302602
SNX14 sorting nexin 14 -0.0300683
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0296678
ENO2 enolase 2 (gamma, neuronal) -0.0295383
TPT1 tumor protein, translationally-controlled 1 -0.0293607
RAI14 retinoic acid induced 14 -0.0291464
TM4SF1 transmembrane 4 L six family member 1 -0.0289977
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0288992
FNIP1 folliculin interacting protein 1 -0.0286485
SVIL supervillin -0.028485
FTH1 ferritin, heavy polypeptide 1 -0.0281118
VEGFA vascular endothelial growth factor A -0.0278538
SH3KBP1 SH3-domain kinase binding protein 1 -0.027824
PYGL phosphorylase, glycogen, liver -0.0276133
UGCG UDP-glucose ceramide glucosyltransferase -0.0275759
DST dystonin -0.0274191
IGF2 insulin-like growth factor 2 -0.0273243
JUN jun proto-oncogene -0.027261
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0270047
CDCP1 CUB domain containing protein 1 -0.0269556
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0262536
RUNX1 runt-related transcription factor 1 -0.0261579
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0260382
GPC5 glypican 5 -0.0259006
DENND1A DENN/MADD domain containing 1A -0.0258538
ZBTB20 zinc finger and BTB domain containing 20 -0.0258185
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0256995
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0256674