| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0850295 |
| TMSB10 | thymosin beta 10 | 0.0829725 |
| KRT18 | keratin 18, type I | 0.0802927 |
| NPSR1 | neuropeptide S receptor 1 | 0.0751123 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0666166 |
| KRT8 | keratin 8, type II | 0.0603166 |
| FAT1 | FAT atypical cadherin 1 | 0.05894 |
| S100A6 | S100 calcium binding protein A6 | 0.0581187 |
| H1-0 | H1.0 linker histone | 0.0573961 |
| ITGA6 | integrin, alpha 6 | 0.0465628 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0463875 |
| KRT19 | keratin 19, type I | 0.0393896 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0369637 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0354841 |
| ANXA2 | annexin A2 | 0.0349966 |
| TNS4 | tensin 4 | 0.034708 |
| PTMA | prothymosin, alpha | 0.0343715 |
| POTEF | POTE ankyrin domain family, member F | 0.0342476 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0335291 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0335152 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0326477 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0320584 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0317544 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0296197 |
| TPI1 | triosephosphate isomerase 1 | 0.0292664 |
| AHNAK | AHNAK nucleoprotein | 0.0288843 |
| CBX3 | chromobox homolog 3 | 0.0280732 |
| FERMT1 | fermitin family member 1 | 0.0278813 |
| PFN1 | profilin 1 | 0.0276541 |
| DSG2 | desmoglein 2 | 0.0276462 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275833 |
| PGK1 | phosphoglycerate kinase 1 | 0.0274117 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.027405 |
| CALB1 | calbindin 1, 28kDa | 0.0267893 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0263609 |
| DSPP | dentin sialophosphoprotein | 0.0260555 |
| PERP | PERP, TP53 apoptosis effector | 0.0259411 |
| ACTN4 | actinin, alpha 4 | 0.0257655 |
| TXNIP | thioredoxin interacting protein | 0.0254957 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0248356 |
| CADPS | Ca++-dependent secretion activator | 0.0240129 |
| RPL18 | ribosomal protein L18 | 0.0239736 |
| FLNB | filamin B, beta | 0.0237865 |
| HMGA1 | high mobility group AT-hook 1 | 0.0235804 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0232936 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0226966 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0219496 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0218459 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0217788 |
| ABHD2 | abhydrolase domain containing 2 | 0.0216104 |
| MUC17 | mucin 17, cell surface associated | 0.021269 |
| LMNA | lamin A/C | 0.021162 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0206742 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0205618 |
| RPLP0 | ribosomal protein, large, P0 | 0.0205087 |
| NRN1 | neuritin 1 | 0.0204833 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0202649 |
| EHBP1 | EH domain binding protein 1 | 0.0202619 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0201716 |
| EPCAM | epithelial cell adhesion molecule | 0.0198659 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0198642 |
| ENO1 | enolase 1, (alpha) | 0.0198414 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0196059 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0196055 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0195663 |
| LDHA | lactate dehydrogenase A | 0.0195276 |
| YBX1 | Y box binding protein 1 | 0.0189779 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0189414 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0188406 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0185899 |
| TUBB | tubulin, beta class I | 0.0185562 |
| EHF | ets homologous factor | 0.0183263 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0182469 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0178632 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0178131 |
| KLK10 | kallikrein-related peptidase 10 | 0.0177988 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0176801 |
| ASPH | aspartate beta-hydroxylase | 0.0175918 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0175819 |
| FOXP1 | forkhead box P1 | 0.0175028 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0174879 |
| PRSS3 | protease, serine, 3 | 0.0173986 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0172038 |
| CCND1 | cyclin D1 | 0.0171338 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0168368 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0168165 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0165935 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0165769 |
| TAGLN2 | transgelin 2 | 0.016311 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0162747 |
| LAMA4 | laminin, alpha 4 | 0.0161273 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0158892 |
| MED13 | mediator complex subunit 13 | 0.0158741 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0158695 |
| MT1X | metallothionein 1X | 0.0158566 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0157917 |
| CDCP1 | CUB domain containing protein 1 | 0.0157447 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0157429 |
| PKP2 | plakophilin 2 | 0.015611 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0156074 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118032 |
| VCL | vinculin | -0.064156 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0481532 |
| RPS6 | ribosomal protein S6 | -0.0333251 |
| RPS29 | ribosomal protein S29 | -0.0316387 |
| FBXO11 | F-box protein 11 | -0.0294218 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0290441 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0264582 |
| RPS27A | ribosomal protein S27a | -0.0259005 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0258877 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0254707 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0253849 |
| GOLGA4 | golgin A4 | -0.0248537 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0243177 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0241153 |
| CALR | calreticulin | -0.0237259 |
| GPHN | gephyrin | -0.0223956 |
| RPL31 | ribosomal protein L31 | -0.0223163 |
| INTS6 | integrator complex subunit 6 | -0.0220083 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0218803 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0199572 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0198917 |
| RPS13 | ribosomal protein S13 | -0.0195147 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0190922 |
| RPS8 | ribosomal protein S8 | -0.018713 |
| RPS25 | ribosomal protein S25 | -0.0186102 |
| HM13 | histocompatibility (minor) 13 | -0.0180992 |
| AREG | amphiregulin | -0.0179901 |
| AGR2 | anterior gradient 2 | -0.0177826 |
| FDPS | farnesyl diphosphate synthase | -0.0177377 |
| CANX | calnexin | -0.0173754 |
| MYO1E | myosin IE | -0.0171557 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0170616 |
| RPL38 | ribosomal protein L38 | -0.0166608 |
| IER3 | immediate early response 3 | -0.0165082 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0165069 |
| RPLP1 | ribosomal protein, large, P1 | -0.0164087 |
| RPL37A | ribosomal protein L37a | -0.0159249 |
| RPS27 | ribosomal protein S27 | -0.0159093 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0159004 |
| SEC24D | SEC24 family member D | -0.0158763 |
| TUFT1 | tuftelin 1 | -0.0151638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.015148 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0151116 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0149182 |
| VMP1 | vacuole membrane protein 1 | -0.014819 |
| RPL7A | ribosomal protein L7a | -0.0146829 |
| AHI1 | Abelson helper integration site 1 | -0.0146363 |
| RPL35A | ribosomal protein L35a | -0.0143727 |
| FTL | ferritin, light polypeptide | -0.0143068 |
| PDLIM5 | PDZ and LIM domain 5 | -0.014144 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0139244 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0138754 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0137611 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0135613 |
| FNDC3B | fibronectin type III domain containing 3B | -0.013424 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0133628 |
| USP53 | ubiquitin specific peptidase 53 | -0.0132466 |
| RYBP | RING1 and YY1 binding protein | -0.013173 |
| SQSTM1 | sequestosome 1 | -0.0131702 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.013161 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0131184 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0127889 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0127793 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0127444 |
| KITLG | KIT ligand | -0.0127231 |
| BRD2 | bromodomain containing 2 | -0.0125729 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0124974 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0124305 |
| ABHD3 | abhydrolase domain containing 3 | -0.0124133 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0123652 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0122087 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0121837 |
| NUP98 | nucleoporin 98kDa | -0.0121626 |
| MORF4L2 | mortality factor 4 like 2 | -0.0120774 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0120648 |
| RTN3 | reticulon 3 | -0.0120471 |
| ATXN1 | ataxin 1 | -0.0119688 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0119561 |
| RPS23 | ribosomal protein S23 | -0.0119366 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0118792 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0118467 |
| AHR | aryl hydrocarbon receptor | -0.0117113 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0116626 |
| SELENOK | selenoprotein K | -0.0116377 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0115066 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0115054 |
| RND3 | Rho family GTPase 3 | -0.0114653 |
| CUX1 | cut-like homeobox 1 | -0.0114197 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0113896 |
| PALLD | palladin, cytoskeletal associated protein | -0.0113645 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0112168 |
| TMEM41B | transmembrane protein 41B | -0.011214 |
| VEGFA | vascular endothelial growth factor A | -0.0112045 |
| RPL9 | ribosomal protein L9 | -0.0111995 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0111941 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0109337 |
| ADIPOR2 | adiponectin receptor 2 | -0.0108501 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0108351 |
