| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.218314 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.157088 |
| STC1 | stanniocalcin 1 | 0.128979 |
| TMSB10 | thymosin beta 10 | 0.120654 |
| FN1 | fibronectin 1 | 0.11401 |
| FAM20C | family with sequence similarity 20, member C | 0.103804 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0932619 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0923595 |
| CDH13 | cadherin 13 | 0.0891094 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0867628 |
| HMGA2 | high mobility group AT-hook 2 | 0.0853736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0851291 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0846953 |
| LOX | lysyl oxidase | 0.0694737 |
| NRG1 | neuregulin 1 | 0.0648453 |
| MTSS1 | metastasis suppressor 1 | 0.0638269 |
| EFNA5 | ephrin-A5 | 0.0593168 |
| GLCCI1 | glucocorticoid induced 1 | 0.0580387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0538624 |
| SMAD3 | SMAD family member 3 | 0.0536838 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0520232 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0509627 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0508375 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0500032 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.049792 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0486337 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.047366 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0469331 |
| S100A6 | S100 calcium binding protein A6 | 0.0454376 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0453557 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0438076 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0434337 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0432649 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0431508 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0430027 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0427785 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0427378 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0423661 |
| RAI14 | retinoic acid induced 14 | 0.0422691 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0416708 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0407892 |
| PYGL | phosphorylase, glycogen, liver | 0.0397627 |
| FNBP1 | formin binding protein 1 | 0.0392197 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0385213 |
| MT2A | metallothionein 2A | 0.0377605 |
| CLMP | CXADR-like membrane protein | 0.0375824 |
| PRRX1 | paired related homeobox 1 | 0.0370394 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0365825 |
| PTMA | prothymosin, alpha | 0.0339912 |
| SEPTIN9 | septin 9 | 0.0334693 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.033384 |
| CUX1 | cut-like homeobox 1 | 0.033374 |
| NAV2 | neuron navigator 2 | 0.0329951 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0329651 |
| IL1B | interleukin 1, beta | 0.0327774 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326657 |
| S100A10 | S100 calcium binding protein A10 | 0.0326037 |
| NAV1 | neuron navigator 1 | 0.032532 |
| NRP1 | neuropilin 1 | 0.0325274 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0324758 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0321937 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0320839 |
| RPL32 | ribosomal protein L32 | 0.031823 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0316728 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0315912 |
| EGFR | epidermal growth factor receptor | 0.0313064 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0306031 |
| TGM2 | transglutaminase 2 | 0.0301709 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0298818 |
| ETV6 | ets variant 6 | 0.0298611 |
| RPS29 | ribosomal protein S29 | 0.0296846 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0294872 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0292418 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0289184 |
| TMEM165 | transmembrane protein 165 | 0.0286289 |
| TMSB4X | thymosin beta 4, X-linked | 0.0284965 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0283634 |
| RPS19 | ribosomal protein S19 | 0.0282444 |
| BMERB1 | bMERB domain containing 1 | 0.0282054 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0275466 |
| RPS8 | ribosomal protein S8 | 0.0274053 |
| RPL31 | ribosomal protein L31 | 0.0270777 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0269775 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0267807 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0266527 |
| HIP1 | huntingtin interacting protein 1 | 0.0264494 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0263311 |
| OXR1 | oxidation resistance 1 | 0.0260923 |
| ZFHX3 | zinc finger homeobox 3 | 0.0256618 |
| BPTF | bromodomain PHD finger transcription factor | 0.0255839 |
| RND3 | Rho family GTPase 3 | 0.0255495 |
| FBN1 | fibrillin 1 | 0.0254576 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0253844 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0251262 |
| RPL37A | ribosomal protein L37a | 0.024807 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0247887 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0247644 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0247422 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247268 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0246579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0998307 |
| PCBP2 | poly(rC) binding protein 2 | -0.0622677 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0572199 |
| FAM13A | family with sequence similarity 13, member A | -0.0560024 |
| RBM39 | RNA binding motif protein 39 | -0.0556266 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0552783 |
| HELZ | helicase with zinc finger | -0.0544196 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.050156 |
| ATP13A3 | ATPase type 13A3 | -0.0495849 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0495306 |
| SPAG9 | sperm associated antigen 9 | -0.0485698 |
| USP3 | ubiquitin specific peptidase 3 | -0.0469288 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0468977 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0431534 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0415248 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0370098 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0368446 |
| TXNRD1 | thioredoxin reductase 1 | -0.0351919 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0351679 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0349527 |
| NUP58 | nucleoporin 58 | -0.0344612 |
| RNF145 | ring finger protein 145 | -0.0339814 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0337279 |
| CCNL1 | cyclin L1 | -0.0335594 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0334273 |
| QKI | QKI, KH domain containing, RNA binding | -0.0333433 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0330686 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0317984 |
| GOLGA4 | golgin A4 | -0.0315272 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0310087 |
| ZNF292 | zinc finger protein 292 | -0.0309578 |
| CD109 | CD109 molecule | -0.0305295 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.029771 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0296569 |
| NBAS | neuroblastoma amplified sequence | -0.029278 |
| PARD3 | par-3 family cell polarity regulator | -0.0289142 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0286933 |
| COPA | coatomer protein complex, subunit alpha | -0.0285295 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0280245 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0274423 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0271512 |
| CDC73 | cell division cycle 73 | -0.0264488 |
| XPO1 | exportin 1 | -0.0260174 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0257706 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0257486 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0255905 |
| OGA | O-GlcNAcase | -0.025468 |
| RLF | rearranged L-myc fusion | -0.0252001 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0249303 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0246548 |
| MYO1B | myosin IB | -0.0245907 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0243486 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0239481 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0236382 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0234719 |
| NPTN | neuroplastin | -0.0234485 |
| SUCO | SUN domain containing ossification factor | -0.0233556 |
| GPC6 | glypican 6 | -0.023249 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0230319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0228268 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0227697 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0227633 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0221122 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0218507 |
| CDK17 | cyclin-dependent kinase 17 | -0.0217544 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0217263 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0214104 |
| AHR | aryl hydrocarbon receptor | -0.0210662 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0206845 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0206268 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0206009 |
| MYOF | myoferlin | -0.020586 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0204994 |
| MED13L | mediator complex subunit 13-like | -0.020383 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0202661 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0200173 |
| YME1L1 | YME1-like 1 ATPase | -0.0197579 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0197208 |
| ANXA1 | annexin A1 | -0.0196974 |
| RIOK3 | RIO kinase 3 | -0.0196904 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0194447 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0192963 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0192328 |
| RTN4 | reticulon 4 | -0.0191667 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0190733 |
| FOXO3 | forkhead box O3 | -0.0189898 |
| ANXA5 | annexin A5 | -0.0189603 |
| ARF4 | ADP-ribosylation factor 4 | -0.0189217 |
| MXD1 | MAX dimerization protein 1 | -0.0189185 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0188345 |
| NCKAP1 | NCK-associated protein 1 | -0.0187972 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0187328 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0187204 |
| PRELID2 | PRELI domain containing 2 | -0.0186612 |
| RBM33 | RNA binding motif protein 33 | -0.0186222 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0186214 |
| TMEM123 | transmembrane protein 123 | -0.0185374 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0185217 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0185139 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0184594 |
