| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.154748 |
| NDRG1 | N-myc downstream regulated 1 | 0.149419 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0938724 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0843377 |
| MT2A | metallothionein 2A | 0.0750105 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0701683 |
| FTL | ferritin, light polypeptide | 0.0692379 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0653916 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0649093 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0611759 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.05931 |
| RBM25 | RNA binding motif protein 25 | 0.0547013 |
| HMGA1 | high mobility group AT-hook 1 | 0.0531595 |
| GOLGA4 | golgin A4 | 0.0530392 |
| CCNL1 | cyclin L1 | 0.0496507 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0487177 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0464585 |
| RNF145 | ring finger protein 145 | 0.045547 |
| FOSL1 | FOS-like antigen 1 | 0.0445667 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0432374 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0386691 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0322658 |
| RPS19 | ribosomal protein S19 | 0.0313488 |
| RPS3 | ribosomal protein S3 | 0.0310374 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0310079 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0309207 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0302708 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0302309 |
| RBM39 | RNA binding motif protein 39 | 0.0297728 |
| FN1 | fibronectin 1 | 0.0291143 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0288706 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288297 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0278746 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0277377 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0272626 |
| MATR3 | matrin 3 | 0.0268966 |
| LAMB3 | laminin, beta 3 | 0.0266629 |
| YBX3 | Y box binding protein 3 | 0.0264554 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0262063 |
| UPP1 | uridine phosphorylase 1 | 0.026162 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0256958 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0256796 |
| SDC4 | syndecan 4 | 0.0256609 |
| TOP1 | topoisomerase (DNA) I | 0.0256141 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0255717 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0254538 |
| G0S2 | G0/G1 switch 2 | 0.0251584 |
| RPL5 | ribosomal protein L5 | 0.0242191 |
| FLNA | filamin A, alpha | 0.0239669 |
| MUC1 | mucin 1, cell surface associated | 0.0239228 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0238257 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0236631 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235289 |
| ZNF292 | zinc finger protein 292 | 0.0229644 |
| RPS12 | ribosomal protein S12 | 0.022816 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0226168 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0224524 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0223811 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0223354 |
| PCBP2 | poly(rC) binding protein 2 | 0.0222465 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0220638 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0211413 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0211317 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0209881 |
| CALR | calreticulin | 0.0208426 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0208366 |
| USP3 | ubiquitin specific peptidase 3 | 0.0208134 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.020722 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.020587 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.020573 |
| RLF | rearranged L-myc fusion | 0.0205277 |
| BRD2 | bromodomain containing 2 | 0.0205223 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0205144 |
| RTN4 | reticulon 4 | 0.0205136 |
| RPL11 | ribosomal protein L11 | 0.0202925 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0202374 |
| AREG | amphiregulin | 0.0201857 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0199362 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0197779 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0197531 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0196833 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0195765 |
| HMGB2 | high mobility group box 2 | 0.019177 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0190395 |
| ANLN | anillin, actin binding protein | 0.0187161 |
| NUP54 | nucleoporin 54kDa | 0.0184403 |
| YBX1 | Y box binding protein 1 | 0.0183293 |
| NUP58 | nucleoporin 58 | 0.0181589 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0178352 |
| CCNI | cyclin I | 0.0176961 |
| TUBA1B | tubulin, alpha 1b | 0.0176309 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0175726 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0175597 |
| NCKAP1 | NCK-associated protein 1 | 0.0174048 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0174025 |
| WTAP | Wilms tumor 1 associated protein | 0.0172859 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0171717 |
| RPL32 | ribosomal protein L32 | 0.0171415 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0170628 |
| NOP58 | NOP58 ribonucleoprotein | 0.0170412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.194156 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.162482 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.130387 |
| EXT1 | exostosin glycosyltransferase 1 | -0.107728 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.101097 |
| FBXO32 | F-box protein 32 | -0.0988698 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0913483 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.091037 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0891389 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0792996 |
| LMO7 | LIM domain 7 | -0.0782096 |
| DSPP | dentin sialophosphoprotein | -0.0727079 |
| ACTG1 | actin gamma 1 | -0.0667811 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0637242 |
| CANX | calnexin | -0.0632477 |
| EFNA5 | ephrin-A5 | -0.0620661 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0584355 |
| DSG2 | desmoglein 2 | -0.0580608 |
| ERBIN | erbb2 interacting protein | -0.0573305 |
| GOLGB1 | golgin B1 | -0.0566473 |
| SQSTM1 | sequestosome 1 | -0.0557833 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0557353 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0551693 |
| VCL | vinculin | -0.0545617 |
| RAI14 | retinoic acid induced 14 | -0.0538113 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0536347 |
| RNF213 | ring finger protein 213 | -0.0526233 |
| CCND1 | cyclin D1 | -0.0520675 |
| DTNA | dystrobrevin, alpha | -0.051311 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.050993 |
| PTK2 | protein tyrosine kinase 2 | -0.0509518 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0507398 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0507362 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0506668 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0497774 |
| AHNAK | AHNAK nucleoprotein | -0.0477287 |
| MX2 | MX dynamin-like GTPase 2 | -0.0474358 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0470512 |
| TPM4 | tropomyosin 4 | -0.0467324 |
| FNIP1 | folliculin interacting protein 1 | -0.0467085 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0461541 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0460494 |
| MYO1E | myosin IE | -0.0459462 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0456675 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0447272 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0440327 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.043196 |
| KRT7 | keratin 7, type II | -0.0429956 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0423809 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0423168 |
| MYO6 | myosin VI | -0.0415278 |
| SVIL | supervillin | -0.041493 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.040975 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0406714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0405724 |
| PLSCR1 | phospholipid scramblase 1 | -0.0405076 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0404924 |
| MCU | mitochondrial calcium uniporter | -0.0404728 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0396816 |
| TMSB4X | thymosin beta 4, X-linked | -0.0396389 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0393405 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0384439 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0383808 |
| MX1 | MX dynamin-like GTPase 1 | -0.0381447 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0381394 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0380841 |
| RPL35A | ribosomal protein L35a | -0.0376774 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0374121 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0367262 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.036535 |
| CD109 | CD109 molecule | -0.0364918 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0363746 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0362152 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0360417 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0360279 |
| ETV6 | ets variant 6 | -0.035937 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0356686 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0354236 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.035363 |
| FBXO34 | F-box protein 34 | -0.0352442 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0350624 |
| PALLD | palladin, cytoskeletal associated protein | -0.0348237 |
| CTSB | cathepsin B | -0.034783 |
| RBM47 | RNA binding motif protein 47 | -0.0345929 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0345276 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0345223 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0344582 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0344409 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0338273 |
| MAP1B | microtubule-associated protein 1B | -0.0328957 |
| RASAL2 | RAS protein activator like 2 | -0.0328301 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0327473 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0314623 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0309082 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0309007 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0306932 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0306847 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305052 |
| SCFD1 | sec1 family domain containing 1 | -0.0303276 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.029858 |
