| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0720542 |
| MT2A | metallothionein 2A | 0.0412518 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0355163 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.029241 |
| SDC4 | syndecan 4 | 0.0282961 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0275028 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247209 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0211545 |
| CAVIN1 | caveolae associated protein 1 | 0.0208209 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0197925 |
| STC1 | stanniocalcin 1 | 0.018103 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0179007 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.017747 |
| SMAD3 | SMAD family member 3 | 0.0173271 |
| RASA3 | RAS p21 protein activator 3 | 0.016906 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0167355 |
| MT1X | metallothionein 1X | 0.0165835 |
| RPL14 | ribosomal protein L14 | 0.0160336 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.0159883 |
| FAM20C | family with sequence similarity 20, member C | 0.0153587 |
| MLPH | melanophilin | 0.0152895 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0148721 |
| RPL26 | ribosomal protein L26 | 0.0146003 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0144512 |
| RPL38 | ribosomal protein L38 | 0.0142793 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0140768 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0137876 |
| KLF6 | Kruppel-like factor 6 | 0.0137396 |
| UBE2I | ubiquitin-conjugating enzyme E2I | 0.0136421 |
| OGA | O-GlcNAcase | 0.0136299 |
| FLNA | filamin A, alpha | 0.0132813 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0132337 |
| HLA-C | major histocompatibility complex, class I, C | 0.0129294 |
| YBX3 | Y box binding protein 3 | 0.0126655 |
| ANLN | anillin, actin binding protein | 0.0125932 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0125869 |
| SMOX | spermine oxidase | 0.0123077 |
| SAFB2 | scaffold attachment factor B2 | 0.0121128 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0117313 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0116187 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0115456 |
| GNAS | GNAS complex locus | 0.0114789 |
| MKI67 | marker of proliferation Ki-67 | 0.0113808 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0112948 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0109865 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.010952 |
| TEX10 | testis expressed 10 | 0.0109267 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0108385 |
| WAPL | WAPL cohesin release factor | 0.0107799 |
| RBM25 | RNA binding motif protein 25 | 0.0107418 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0104681 |
| PRR11 | proline rich 11 | 0.0103805 |
| RNF169 | ring finger protein 169 | 0.0103725 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0101402 |
| TMSB4X | thymosin beta 4, X-linked | 0.0101278 |
| H1-4 | H1.4 linker histone, cluster member | 0.0100598 |
| MIDN | midnolin | 0.00997717 |
| CEP95 | centrosomal protein 95kDa | 0.00992165 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.00975866 |
| KIF4A | kinesin family member 4A | 0.00950032 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | 0.00939563 |
| DENND5A | DENN/MADD domain containing 5A | 0.00934207 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.00927352 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.00920432 |
| PRPF6 | pre-mRNA processing factor 6 | 0.00916775 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00913072 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0090673 |
| PHRF1 | PHD and ring finger domains 1 | 0.00898134 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00891497 |
| OSMR | oncostatin M receptor | 0.00890667 |
| TMEM41B | transmembrane protein 41B | 0.00880479 |
| LIF | leukemia inhibitory factor | 0.00878324 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00876682 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00876132 |
| RPS24 | ribosomal protein S24 | 0.00874481 |
| H1-0 | H1.0 linker histone | 0.0087011 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00869766 |
| ZNF267 | zinc finger protein 267 | 0.008544 |
| CENPE | centromere protein E, 312kDa | 0.00853269 |
| THBS2 | thrombospondin 2 | 0.00827807 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.00827149 |
| TPD52L2 | tumor protein D52-like 2 | 0.00825835 |
| ATXN2L | ataxin 2-like | 0.00820696 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.00819011 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00818221 |
| AHNAK | AHNAK nucleoprotein | 0.00813825 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00809756 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) | 0.00808441 |
| CSNK1E | casein kinase 1, epsilon | 0.00808262 |
| EWSR1 | EWS RNA-binding protein 1 | 0.00807843 |
| INHBA | inhibin, beta A | 0.0080434 |
| RTF2 | replication termination factor 2 | 0.00800026 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.00797493 |
| STK17A | serine/threonine kinase 17a | 0.00793527 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.00793385 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00792348 |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.00790874 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0079035 |
| FUS | FUS RNA binding protein | 0.00789118 |
| RAB13 | RAB13, member RAS oncogene family | 0.00778795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.29034 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191609 |
| FN1 | fibronectin 1 | -0.179345 |
| VIM | vimentin | -0.178731 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.138285 |
| FNDC3B | fibronectin type III domain containing 3B | -0.115111 |
| FRMD4A | FERM domain containing 4A | -0.111514 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.108671 |
| LDHA | lactate dehydrogenase A | -0.10842 |
| HDAC9 | histone deacetylase 9 | -0.0993227 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0913558 |
| CADM1 | cell adhesion molecule 1 | -0.0894662 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0877342 |
| B2M | beta-2-microglobulin | -0.085973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.08585 |
| DST | dystonin | -0.0844463 |
| CD44 | CD44 molecule (Indian blood group) | -0.0819784 |
| PDE10A | phosphodiesterase 10A | -0.0790867 |
| PLIN2 | perilipin 2 | -0.0780877 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0773741 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0769524 |
| VCL | vinculin | -0.0743752 |
| ENO1 | enolase 1, (alpha) | -0.0738512 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0725553 |
| VCAN | versican | -0.072282 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0715167 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.070731 |
| FTL | ferritin, light polypeptide | -0.0663992 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0661901 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0633265 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0632649 |
| MYOF | myoferlin | -0.0617168 |
| RPS6 | ribosomal protein S6 | -0.0594869 |
| EGR1 | early growth response 1 | -0.0566335 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0563337 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0560613 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0558169 |
| VEGFA | vascular endothelial growth factor A | -0.0543306 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0542222 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0535789 |
| UBC | ubiquitin C | -0.052418 |
| DIAPH2 | diaphanous-related formin 2 | -0.0518951 |
| PKM | pyruvate kinase, muscle | -0.0515437 |
| MORF4L2 | mortality factor 4 like 2 | -0.0508825 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0508651 |
| HMGA2 | high mobility group AT-hook 2 | -0.0502647 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0502038 |
| FNIP1 | folliculin interacting protein 1 | -0.0495199 |
| CTSD | cathepsin D | -0.0492256 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0489493 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0487123 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0482518 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0481096 |
| ATXN1 | ataxin 1 | -0.0473432 |
| CANX | calnexin | -0.0465131 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0460747 |
| CALR | calreticulin | -0.0459275 |
| QKI | QKI, KH domain containing, RNA binding | -0.0458651 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0454707 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0454513 |
| TNS3 | tensin 3 | -0.0450693 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0448457 |
| ASPH | aspartate beta-hydroxylase | -0.044516 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0444639 |
| SQSTM1 | sequestosome 1 | -0.0442803 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0436115 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.043327 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0431238 |
| GOLGA4 | golgin A4 | -0.0424236 |
| PCBP2 | poly(rC) binding protein 2 | -0.0423911 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0407823 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0397403 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0388677 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.038049 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0379926 |
| HLA-A | major histocompatibility complex, class I, A | -0.037736 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0374701 |
| HELZ | helicase with zinc finger | -0.0374574 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0373253 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0372307 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0371826 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0369283 |
| TPM1 | tropomyosin 1 (alpha) | -0.0366739 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0366638 |
| INTS6 | integrator complex subunit 6 | -0.0366086 |
| JMJD1C | jumonji domain containing 1C | -0.0365595 |
| ZNF292 | zinc finger protein 292 | -0.0365553 |
| GOLGB1 | golgin B1 | -0.0363282 |
| ANXA2 | annexin A2 | -0.036207 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0354927 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0351161 |
| SETD5 | SET domain containing 5 | -0.0351121 |
| CLIC4 | chloride intracellular channel 4 | -0.0346652 |
| COL1A2 | collagen, type I, alpha 2 | -0.0344531 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0342063 |
| GPC6 | glypican 6 | -0.0340929 |
| OPTN | optineurin | -0.0339494 |
| TAPBP | TAP binding protein (tapasin) | -0.0338524 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0337398 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0335804 |
