| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.125069 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0691589 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0484996 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0464896 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0452143 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0446633 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0440129 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0408151 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0383519 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0382431 |
| CAVIN1 | caveolae associated protein 1 | 0.0372266 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0370269 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0354633 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0346878 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0335424 |
| EGR1 | early growth response 1 | 0.0330582 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0321992 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0320381 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0319773 |
| OGA | O-GlcNAcase | 0.0315054 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0314716 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0313328 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0308029 |
| RORA | RAR-related orphan receptor A | 0.0305905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0297347 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0294028 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0291852 |
| ENO1 | enolase 1, (alpha) | 0.0283242 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0277677 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0273217 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0273023 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0271345 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.026898 |
| JMJD1C | jumonji domain containing 1C | 0.0268725 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0268358 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0264415 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0263713 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0260197 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0259015 |
| CD44 | CD44 molecule (Indian blood group) | 0.0255625 |
| WDR45B | WD repeat domain 45B | 0.025496 |
| VMP1 | vacuole membrane protein 1 | 0.0254079 |
| CORO1C | coronin, actin binding protein, 1C | 0.0253973 |
| AHR | aryl hydrocarbon receptor | 0.0251054 |
| SBF2 | SET binding factor 2 | 0.0249305 |
| SLMAP | sarcolemma associated protein | 0.0248386 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0244569 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0244204 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0244195 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0235787 |
| MAP4 | microtubule-associated protein 4 | 0.0232554 |
| SDC4 | syndecan 4 | 0.0231364 |
| NEMF | nuclear export mediator factor | 0.0230373 |
| MYLK | myosin light chain kinase | 0.0230235 |
| RAD21 | RAD21 homolog (S. pombe) | 0.022839 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0228028 |
| FOSL2 | FOS-like antigen 2 | 0.0226773 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0226415 |
| FBXO34 | F-box protein 34 | 0.0224673 |
| GPATCH8 | G patch domain containing 8 | 0.0224576 |
| SEPTIN10 | septin 10 | 0.022438 |
| ATP13A3 | ATPase type 13A3 | 0.0223171 |
| RPL14 | ribosomal protein L14 | 0.0221369 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0218986 |
| RSF1 | remodeling and spacing factor 1 | 0.0217558 |
| STK17A | serine/threonine kinase 17a | 0.0217042 |
| RPL26 | ribosomal protein L26 | 0.0215817 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0214432 |
| CST3 | cystatin C | 0.0213474 |
| CDYL | chromodomain protein, Y-like | 0.0210859 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.020951 |
| CUL4B | cullin 4B | 0.0209492 |
| TMEM131 | transmembrane protein 131 | 0.0208358 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0207078 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0206254 |
| YME1L1 | YME1-like 1 ATPase | 0.020586 |
| BBX | bobby sox homolog (Drosophila) | 0.0205279 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0204659 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0203083 |
| PRKCA | protein kinase C, alpha | 0.0199904 |
| PER1 | period circadian clock 1 | 0.019984 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0199292 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0199277 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0199211 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.0198217 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0196963 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.019628 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0195555 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0195489 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0195095 |
| TSC22D1 | TSC22 domain family, member 1 | 0.019435 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0194281 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0193962 |
| UBE3A | ubiquitin protein ligase E3A | 0.019263 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.019151 |
| SNX14 | sorting nexin 14 | 0.0191091 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0188985 |
| ZNF516 | zinc finger protein 516 | 0.0188531 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0187701 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0187618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.34695 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.289759 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0998843 |
| TMSB10 | thymosin beta 10 | -0.0972547 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0913812 |
| MT2A | metallothionein 2A | -0.0887645 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0834328 |
| VIM | vimentin | -0.0727031 |
| CADM1 | cell adhesion molecule 1 | -0.0724376 |
| MAP1B | microtubule-associated protein 1B | -0.0712341 |
| LOX | lysyl oxidase | -0.066825 |
| CDH13 | cadherin 13 | -0.0664097 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0627066 |
| CALU | calumenin | -0.0614685 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0574328 |
| COL5A1 | collagen, type V, alpha 1 | -0.0544964 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0530613 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0519627 |
| NDRG1 | N-myc downstream regulated 1 | -0.0517429 |
| LOXL2 | lysyl oxidase-like 2 | -0.0517024 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0516098 |
| GOLGA4 | golgin A4 | -0.0482816 |
| FTL | ferritin, light polypeptide | -0.0482584 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0473197 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0468632 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0464371 |
| COPA | coatomer protein complex, subunit alpha | -0.0447882 |
| NAV1 | neuron navigator 1 | -0.0445431 |
| ACTG1 | actin gamma 1 | -0.0414096 |
| CALD1 | caldesmon 1 | -0.0406411 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.040135 |
| ITGAV | integrin, alpha V | -0.0399484 |
| MORF4L2 | mortality factor 4 like 2 | -0.0389445 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0382548 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0374081 |
| RPS3 | ribosomal protein S3 | -0.0373123 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0368493 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0364414 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0364228 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0364036 |
| ATXN1 | ataxin 1 | -0.0359333 |
| ZNF395 | zinc finger protein 395 | -0.0358981 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0357554 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0356123 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0341148 |
| CALR | calreticulin | -0.033778 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0331583 |
| B2M | beta-2-microglobulin | -0.0330938 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0330217 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0328712 |
| RPS6 | ribosomal protein S6 | -0.0320781 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0320083 |
| NBAS | neuroblastoma amplified sequence | -0.0318594 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0315628 |
| MED13L | mediator complex subunit 13-like | -0.030867 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0305005 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0302384 |
| PTGES2 | prostaglandin E synthase 2 | -0.030118 |
| HLA-A | major histocompatibility complex, class I, A | -0.0299982 |
| MGLL | monoglyceride lipase | -0.0296938 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0296684 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0293739 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0287322 |
| PCBP2 | poly(rC) binding protein 2 | -0.0279847 |
| RPL35A | ribosomal protein L35a | -0.02796 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0277708 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0274462 |
| SRPK2 | SRSF protein kinase 2 | -0.0273484 |
| SETD5 | SET domain containing 5 | -0.0269547 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0269371 |
| COL1A2 | collagen, type I, alpha 2 | -0.0268955 |
| HMGA2 | high mobility group AT-hook 2 | -0.0266823 |
| CD99 | CD99 molecule | -0.0266003 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0264862 |
| MYOF | myoferlin | -0.0264046 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0263898 |
| RTN4 | reticulon 4 | -0.0263446 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0260194 |
| PGM3 | phosphoglucomutase 3 | -0.0259258 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0258694 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0256881 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0255548 |
| CDK6 | cyclin-dependent kinase 6 | -0.0254697 |
| NKTR | natural killer cell triggering receptor | -0.0253719 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.025242 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0249083 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0248351 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0248179 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0246197 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0243788 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.024087 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0239989 |
| USP34 | ubiquitin specific peptidase 34 | -0.0239934 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0239904 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0239309 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0237354 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0236334 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0234012 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0231444 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.023103 |
