| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dexmedetomidine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dexmedetomidine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0686901 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0416003 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0358071 |
| RBM25 | RNA binding motif protein 25 | 0.0318999 |
| OGA | O-GlcNAcase | 0.0284633 |
| WDR45B | WD repeat domain 45B | 0.0225385 |
| RBM39 | RNA binding motif protein 39 | 0.0215318 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0210003 |
| SMOX | spermine oxidase | 0.0199596 |
| RPS12 | ribosomal protein S12 | 0.0194316 |
| RNF145 | ring finger protein 145 | 0.0192192 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0190069 |
| RPS29 | ribosomal protein S29 | 0.0184376 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0179493 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.0177615 |
| RPL37A | ribosomal protein L37a | 0.017092 |
| TPR | translocated promoter region, nuclear basket protein | 0.0169584 |
| YBX3 | Y box binding protein 3 | 0.0168917 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.016746 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0166971 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0165352 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0164423 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0159126 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0154654 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0153619 |
| RPL26 | ribosomal protein L26 | 0.0150689 |
| PER1 | period circadian clock 1 | 0.0149684 |
| RPLP1 | ribosomal protein, large, P1 | 0.0149558 |
| RPL13A | ribosomal protein L13a | 0.0147011 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0146884 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0146593 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.014092 |
| NUP58 | nucleoporin 58 | 0.0140264 |
| H1-0 | H1.0 linker histone | 0.0139523 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.013899 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0137991 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0137757 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0136259 |
| MT1X | metallothionein 1X | 0.0132378 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0131427 |
| RPL32 | ribosomal protein L32 | 0.0130615 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0128773 |
| RPS20 | ribosomal protein S20 | 0.0124648 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0119623 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0118841 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0117644 |
| HOMER2 | homer scaffolding protein 2 | 0.011501 |
| RPS3 | ribosomal protein S3 | 0.0113698 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0111298 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0109548 |
| NOP58 | NOP58 ribonucleoprotein | 0.0109037 |
| SDC4 | syndecan 4 | 0.0108793 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0108691 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0107321 |
| RPS21 | ribosomal protein S21 | 0.01071 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0106122 |
| RPL5 | ribosomal protein L5 | 0.0105392 |
| RPS19 | ribosomal protein S19 | 0.0104294 |
| RPL9 | ribosomal protein L9 | 0.0103517 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0103475 |
| PELO | pelota homolog (Drosophila) | 0.010043 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0099817 |
| CDC27 | cell division cycle 27 | 0.00993929 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00993638 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.00991095 |
| RPS8 | ribosomal protein S8 | 0.00989386 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00983802 |
| RPL38 | ribosomal protein L38 | 0.00980128 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00976422 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00966028 |
| SF1 | splicing factor 1 | 0.00956993 |
| NEK7 | NIMA-related kinase 7 | 0.00949696 |
| RPS2 | ribosomal protein S2 | 0.0094151 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00938467 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00934889 |
| PCBP2 | poly(rC) binding protein 2 | 0.00924467 |
| FOSL1 | FOS-like antigen 1 | 0.00921516 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.00917941 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00917606 |
| CD163L1 | CD163 molecule-like 1 | 0.00908607 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.00908257 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0090787 |
| RPS24 | ribosomal protein S24 | 0.00904432 |
| USP3 | ubiquitin specific peptidase 3 | 0.00903085 |
| FOXJ3 | forkhead box J3 | 0.00902439 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00894163 |
| WTAP | Wilms tumor 1 associated protein | 0.00892477 |
| RPL28 | ribosomal protein L28 | 0.00885925 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00885862 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.00872987 |
| RPL23A | ribosomal protein L23a | 0.00870658 |
| SARNP | SAP domain containing ribonucleoprotein | 0.00870497 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0086478 |
| PFDN2 | prefoldin subunit 2 | 0.00859613 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00858344 |
| RPL12 | ribosomal protein L12 | 0.00854401 |
| XPO1 | exportin 1 | 0.00847483 |
| CABIN1 | calcineurin binding protein 1 | 0.00843815 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.00835687 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00835354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.315983 |
| NRG1 | neuregulin 1 | -0.284559 |
| HMGA2 | high mobility group AT-hook 2 | -0.191507 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.174298 |
| ASPH | aspartate beta-hydroxylase | -0.153294 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0991041 |
| GLIS3 | GLIS family zinc finger 3 | -0.0964969 |
| CANX | calnexin | -0.0964895 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0957345 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0942766 |
| VCL | vinculin | -0.0911146 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0904563 |
| EFNA5 | ephrin-A5 | -0.0897022 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0862509 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0807729 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0785873 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0780364 |
| ITGA1 | integrin, alpha 1 | -0.0771595 |
| SQSTM1 | sequestosome 1 | -0.0770626 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0704732 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0679217 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0663963 |
| INTS6 | integrator complex subunit 6 | -0.0655644 |
| RAI14 | retinoic acid induced 14 | -0.0649268 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.063403 |
| STC2 | stanniocalcin 2 | -0.0613852 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0612779 |
| SYT1 | synaptotagmin I | -0.0608879 |
| PLIN2 | perilipin 2 | -0.0607716 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0604852 |
| AEBP2 | AE binding protein 2 | -0.0602602 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0592883 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0581815 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.056415 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0550529 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0549941 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0545963 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0520351 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0513798 |
| MAP1B | microtubule-associated protein 1B | -0.0502889 |
| NDRG1 | N-myc downstream regulated 1 | -0.049851 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0492004 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0477898 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.047265 |
| GPC6 | glypican 6 | -0.046428 |
| ENO1 | enolase 1, (alpha) | -0.0459698 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0458056 |
| AHR | aryl hydrocarbon receptor | -0.0454558 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0453412 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0451351 |
| GPATCH2L | G patch domain containing 2-like | -0.0448676 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0444693 |
| PRKCA | protein kinase C, alpha | -0.0438641 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0427033 |
| SFTPA2 | surfactant protein A2 | -0.042552 |
| CADM1 | cell adhesion molecule 1 | -0.0424266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0420338 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0417771 |
| PTK2 | protein tyrosine kinase 2 | -0.0415974 |
| RASAL2 | RAS protein activator like 2 | -0.0415832 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.041416 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0411501 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0403167 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0398123 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0397724 |
| B2M | beta-2-microglobulin | -0.0375692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0375087 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0374351 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0374275 |
| LOXL2 | lysyl oxidase-like 2 | -0.0366245 |
| DST | dystonin | -0.036537 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0359628 |
| MCL1 | myeloid cell leukemia 1 | -0.0358801 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0358604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0356242 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0353034 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.035187 |
| NRP1 | neuropilin 1 | -0.0344471 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0339513 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0333235 |
| TNS3 | tensin 3 | -0.0326347 |
| HMGA1 | high mobility group AT-hook 1 | -0.0326115 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322551 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0320124 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0319934 |
| MYOF | myoferlin | -0.0319157 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0308223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0305949 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0305645 |
| RAD51B | RAD51 paralog B | -0.0304161 |
| LRRC23 | leucine rich repeat containing 23 | -0.0302071 |
| GOLGB1 | golgin B1 | -0.0301429 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301142 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0298917 |
| ACTG1 | actin gamma 1 | -0.0298172 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0297094 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0294434 |
| LOX | lysyl oxidase | -0.029356 |
| TMEM156 | transmembrane protein 156 | -0.0290906 |
| LYST | lysosomal trafficking regulator | -0.0287316 |
