Diabetic Nephropathy_Renal Tissue_GSE1009 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1009
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Genes

600 genes differentially expressed during Diabetic Nephropathy_Renal Tissue_GSE1009 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
LOC391322 D-dopachrome tautomerase-like 5.75487
MSL3 male-specific lethal 3 homolog (Drosophila) 4.98948
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) 3.12466
ESRRA estrogen-related receptor alpha 2.72225
TM4SF5 transmembrane 4 L six family member 5 2.48119
TCN2 transcobalamin II 2.44481
HYAL1 hyaluronoglucosaminidase 1 2.0983
SKI SKI proto-oncogene 2.06564
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.97826
TUBGCP2 tubulin, gamma complex associated protein 2 1.84331
ACO1 aconitase 1, soluble 1.83127
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.75244
TSPO2 translocator protein 2 1.696
IDS iduronate 2-sulfatase 1.68793
WDR62 WD repeat domain 62 1.58674
CCIN calicin 1.54326
MRPL3 mitochondrial ribosomal protein L3 1.46025
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.45186
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.39894
NECAB3 N-terminal EF-hand calcium binding protein 3 1.37856
TONSL tonsoku-like, DNA repair protein 1.30294
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 1.26347
MYO16 myosin XVI 1.24145
ADAR adenosine deaminase, RNA-specific 1.17949
GRIP2 glutamate receptor interacting protein 2 1.16957
ADORA2B adenosine A2b receptor 1.12508
CROCC ciliary rootlet coiled-coil, rootletin 1.10276
ADRA2A adrenoceptor alpha 2A 1.10209
SZRD1 SUZ RNA binding domain containing 1 1.0978
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 1.07087
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 1.02903
ADCY1 adenylate cyclase 1 (brain) 1.01505
CAV2 caveolin 2 1.01367
THY1 Thy-1 cell surface antigen 1.00388
RAP1A RAP1A, member of RAS oncogene family 0.979861
SMYD5 SMYD family member 5 0.974543
ZNF202 zinc finger protein 202 0.955522
CACTIN cactin, spliceosome C complex subunit 0.953208
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.942831
PTPRK protein tyrosine phosphatase, receptor type, K 0.935295
MRPL23 mitochondrial ribosomal protein L23 0.931203
SETD1B SET domain containing 1B 0.930338
TNNT3 troponin T type 3 (skeletal, fast) 0.928212
MADD MAP-kinase activating death domain 0.88358
TPMT thiopurine S-methyltransferase 0.87277
CD69 CD69 molecule 0.870531
DAZL deleted in azoospermia-like 0.869038
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.868609
DIAPH1 diaphanous-related formin 1 0.868324
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.866974
CPZ carboxypeptidase Z 0.863709
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.861501
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 0.860746
BMS1 BMS1 ribosome biogenesis factor 0.859773
ZBTB17 zinc finger and BTB domain containing 17 0.858846
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.857713
RXRB retinoid X receptor, beta 0.852544
ZNF101 zinc finger protein 101 0.851028
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.850397
PHGDH phosphoglycerate dehydrogenase 0.847404
PTK2 protein tyrosine kinase 2 0.834303
PPAP2C phosphatidic acid phosphatase type 2C 0.833469
MUC3A mucin 3A, cell surface associated 0.829464
SLIT2 slit homolog 2 (Drosophila) 0.829037
MATN1 matrilin 1, cartilage matrix protein 0.8272
ZNHIT1 zinc finger, HIT-type containing 1 0.826543
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.825242
KLHL35 kelch-like family member 35 0.82269
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.814635
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.810204
CCHCR1 coiled-coil alpha-helical rod protein 1 0.809407
DENND4B DENN/MADD domain containing 4B 0.796327
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 0.79547
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 0.794352
HLA-DOA major histocompatibility complex, class II, DO alpha 0.786988
FRMPD4 FERM and PDZ domain containing 4 0.786021
MYOM1 myomesin 1 0.780714
CHD8 chromodomain helicase DNA binding protein 8 0.770048
PCNXL2 pecanex-like 2 (Drosophila) 0.769299
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.767341
GNPDA1 glucosamine-6-phosphate deaminase 1 0.762398
BRSK2 BR serine/threonine kinase 2 0.758965
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.758664
TLX2 T-cell leukemia homeobox 2 0.756504
MMRN1 multimerin 1 0.75035
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.748729
ACD adrenocortical dysplasia homolog (mouse) 0.741077
ECRP ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene 0.727182
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.725924
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.724837
SCAPER S-phase cyclin A-associated protein in the ER 0.72444
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.72158
IL4 interleukin 4 0.716583
CP ceruloplasmin (ferroxidase) 0.709205
KRT17 keratin 17, type I 0.706841
PCBP3 poly(rC) binding protein 3 0.706616
GCDH glutaryl-CoA dehydrogenase 0.706609
LCN1 lipocalin 1 0.701669
LRP6 low density lipoprotein receptor-related protein 6 0.698837
DPF1 D4, zinc and double PHD fingers family 1 0.697487
COL4A2 collagen, type IV, alpha 2 0.694578
BATF basic leucine zipper transcription factor, ATF-like 0.691569
ADGRB2 adhesion G protein-coupled receptor B2 0.690288
KIAA0408 KIAA0408 0.68745
TCL1A T-cell leukemia/lymphoma 1A 0.678327
THOP1 thimet oligopeptidase 1 0.678068
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.677051
FEV FEV (ETS oncogene family) 0.674844
CNTN2 contactin 2 (axonal) 0.671725
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.66975
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.66432
BPHL biphenyl hydrolase-like (serine hydrolase) 0.663001
SLC35B1 solute carrier family 35, member B1 0.660215
PPT2 palmitoyl-protein thioesterase 2 0.660109
DUSP9 dual specificity phosphatase 9 0.657298
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.642999
TOP3B topoisomerase (DNA) III beta 0.640426
STAR steroidogenic acute regulatory protein 0.634852
FGR FGR proto-oncogene, Src family tyrosine kinase 0.633723
FEM1C fem-1 homolog c (C. elegans) 0.630582
ETV4 ets variant 4 0.630161
TRRAP transformation/transcription domain-associated protein 0.627874
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.621746
RARG retinoic acid receptor, gamma 0.620385
SMTN smoothelin 0.620014
SPN sialophorin 0.610341
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.607327
KIAA0195 KIAA0195 0.606368
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 0.606339
CRYAB crystallin, alpha B 0.604409
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.601628
JAG1 jagged 1 0.600257
MARCO macrophage receptor with collagenous structure 0.599757
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.598042
MFAP2 microfibrillar-associated protein 2 0.590429
ZNF337 zinc finger protein 337 0.588653
DAPK2 death-associated protein kinase 2 0.587064
CTF1 cardiotrophin 1 0.585589
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.584946
CCL3 chemokine (C-C motif) ligand 3 0.582127
GJB1 gap junction protein, beta 1, 32kDa 0.580817
LTB lymphotoxin beta (TNF superfamily, member 3) 0.579592
THBS2 thrombospondin 2 0.579233
CXCR2 chemokine (C-X-C motif) receptor 2 0.57821
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.576805
GJB3 gap junction protein, beta 3, 31kDa 0.576692
GNAS GNAS complex locus 0.573544
PTGDR2 prostaglandin D2 receptor 2 0.572594
RPH3A rabphilin 3A 0.571145
AIP aryl hydrocarbon receptor interacting protein 0.566419
ZNF391 zinc finger protein 391 0.565332
SIGLEC7 sialic acid binding Ig-like lectin 7 0.565058
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.56363
CRTC1 CREB regulated transcription coactivator 1 0.562191
CXCL3 chemokine (C-X-C motif) ligand 3 0.560002
GPR50 G protein-coupled receptor 50 0.555117
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 0.554511
ZDHHC3 zinc finger, DHHC-type containing 3 0.553267
CRH corticotropin releasing hormone 0.55173
TOM1 target of myb1 (chicken) 0.551642
CEP152 centrosomal protein 152kDa 0.550455
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.548839
LOC100507424 uncharacterized LOC100507424 0.548149
CHP1 calcineurin-like EF-hand protein 1 0.545744
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.542963
QPCT glutaminyl-peptide cyclotransferase 0.54272
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.541937
METTL13 methyltransferase like 13 0.541453
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.541184
SRRT serrate, RNA effector molecule 0.538213
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.536422
GPR161 G protein-coupled receptor 161 0.53623
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.533674
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.532411
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.531785
FGFR1 fibroblast growth factor receptor 1 0.529269
MOGS mannosyl-oligosaccharide glucosidase 0.529216
RALB v-ral simian leukemia viral oncogene homolog B 0.528196
TDGF1 teratocarcinoma-derived growth factor 1 0.527994
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.527617
CSHL1 chorionic somatomammotropin hormone-like 1 0.526547
ACO2 aconitase 2, mitochondrial 0.526301
PAX3 paired box 3 0.524313
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 0.522599
USP19 ubiquitin specific peptidase 19 0.520751
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.519696
MAG myelin associated glycoprotein 0.519223
PRKD2 protein kinase D2 0.518253
SQSTM1 sequestosome 1 0.51814
FOXN1 forkhead box N1 0.517857
TOB2 transducer of ERBB2, 2 0.517165
EDA ectodysplasin A 0.517069
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.515179
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.507426
ANXA6 annexin A6 0.505536
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.505276
GBX1 gastrulation brain homeobox 1 0.504403
EGR1 early growth response 1 0.503272
CHKB choline kinase beta 0.502585
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.500973
CA11 carbonic anhydrase XI 0.494617
RBM6 RNA binding motif protein 6 0.494516
CD300A CD300a molecule 0.492568
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.490712
CSK c-src tyrosine kinase 0.487834
MCRS1 microspherule protein 1 0.486462
GDF5 growth differentiation factor 5 0.486163
SOX1 SRY (sex determining region Y)-box 1 0.485951
IFFO1 intermediate filament family orphan 1 0.484439
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.484429
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.482642
SAG S-antigen; retina and pineal gland (arrestin) 0.481202
PHB2 prohibitin 2 0.480655
MORC2 MORC family CW-type zinc finger 2 0.479027
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.477639
ATP10B ATPase, class V, type 10B 0.47551
GLDC glycine dehydrogenase (decarboxylating) 0.471698
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.470231
TCP10 t-complex 10 0.469582
TGFA transforming growth factor, alpha 0.469159
CCL19 chemokine (C-C motif) ligand 19 0.467176
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.465475
IGKV1OR2-118 immunoglobulin kappa variable 1/OR2-118 (pseudogene) 0.463056
IL24 interleukin 24 0.461901
RPS26 ribosomal protein S26 0.460968
CADM4 cell adhesion molecule 4 0.458825
AGFG2 ArfGAP with FG repeats 2 0.457599
KRT7 keratin 7, type II 0.456971
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.456825
PARVB parvin, beta 0.456726
AQP5 aquaporin 5 0.456171
EBP emopamil binding protein (sterol isomerase) 0.45538
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 0.45446
IGLL1 immunoglobulin lambda-like polypeptide 1 0.45408
SIT1 signaling threshold regulating transmembrane adaptor 1 0.45318
RAP1GAP RAP1 GTPase activating protein 0.451011
CDC23 cell division cycle 23 0.450761
HAB1 B1 for mucin 0.449973
TST thiosulfate sulfurtransferase (rhodanese) 0.449831
DMWD dystrophia myotonica, WD repeat containing 0.448465
PRSS2 protease, serine, 2 (trypsin 2) 0.447958
FOXO1 forkhead box O1 0.446114
CAPN3 calpain 3, (p94) 0.446109
INHBB inhibin, beta B 0.444496
HSF4 heat shock transcription factor 4 0.443485
GAB1 GRB2-associated binding protein 1 0.443204
KHNYN KH and NYN domain containing 0.442366
ACVR1B activin A receptor, type IB 0.441701
RCE1 Ras converting CAAX endopeptidase 1 0.441152
ZFYVE26 zinc finger, FYVE domain containing 26 0.439637
PRKX protein kinase, X-linked 0.439164
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.438331
AHNAK2 AHNAK nucleoprotein 2 0.436633
CARD10 caspase recruitment domain family, member 10 0.435696
PRB1 proline-rich protein BstNI subfamily 1 0.435199
DVL1 dishevelled segment polarity protein 1 0.434161
MYO9B myosin IXB 0.431142
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.430563
ILVBL ilvB (bacterial acetolactate synthase)-like 0.430563
SH3BP1 SH3-domain binding protein 1 0.430441
ICA1 islet cell autoantigen 1, 69kDa 0.43016
APOC4 apolipoprotein C-IV 0.430096
CAPNS1 calpain, small subunit 1 0.429354
LMO2 LIM domain only 2 (rhombotin-like 1) 0.429184
SPTB spectrin, beta, erythrocytic 0.428343
PLAU plasminogen activator, urokinase 0.428284
POU2F2 POU class 2 homeobox 2 0.427961
TPD52L2 tumor protein D52-like 2 0.423306
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.423042
IER2 immediate early response 2 0.422981
PHF21A PHD finger protein 21A 0.42239
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.421368
CDC6 cell division cycle 6 0.420884
PICK1 protein interacting with PRKCA 1 0.420797
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.420699
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.420479
BAMBI BMP and activin membrane-bound inhibitor 0.418582
MT3 metallothionein 3 0.418543
SULT4A1 sulfotransferase family 4A, member 1 0.417974
C1QL1 complement component 1, q subcomponent-like 1 0.416563
ACP1 acid phosphatase 1, soluble 0.414839
SOD3 superoxide dismutase 3, extracellular 0.411787
NNT nicotinamide nucleotide transhydrogenase 0.41086
ALDOC aldolase C, fructose-bisphosphate 0.410769
CA4 carbonic anhydrase IV 0.409208
MAT1A methionine adenosyltransferase I, alpha 0.405733
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.404109
DOC2B double C2-like domains, beta 0.402875
TTC22 tetratricopeptide repeat domain 22 0.402538
PRAF2 PRA1 domain family, member 2 0.402102
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.400509
UBN1 ubinuclein 1 0.399376
PNMT phenylethanolamine N-methyltransferase 0.398543
ENO1 enolase 1, (alpha) 0.397264
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.39607
POM121L1P POM121 transmembrane nucleoporin-like 1, pseudogene 0.395202
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.394907
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.393695
KIF13B kinesin family member 13B 0.392484
ZMIZ2 zinc finger, MIZ-type containing 2 0.392398

decreased expression

Symbol Name Standardized Value
SUSD6 sushi domain containing 6 -3.60201
SOD1 superoxide dismutase 1, soluble -2.74725
THSD7A thrombospondin, type I, domain containing 7A -2.63654
KLHL9 kelch-like family member 9 -2.11695
PABPN1 poly(A) binding protein, nuclear 1 -1.91088
WRB tryptophan rich basic protein -1.78613
PAM peptidylglycine alpha-amidating monooxygenase -1.66794
PFN2 profilin 2 -1.63199
PLA2G15 phospholipase A2, group XV -1.62811
PTDSS1 phosphatidylserine synthase 1 -1.61722
GDI2 GDP dissociation inhibitor 2 -1.58767
MARK3 MAP/microtubule affinity-regulating kinase 3 -1.50713
ATP11B ATPase, class VI, type 11B -1.46862
IQGAP2 IQ motif containing GTPase activating protein 2 -1.42188
FAM50B family with sequence similarity 50, member B -1.41723
HDLBP high density lipoprotein binding protein -1.37344
PLCE1 phospholipase C, epsilon 1 -1.34737
MORF4L2 mortality factor 4 like 2 -1.34095
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -1.27973
GLOD4 glyoxalase domain containing 4 -1.15979
SH2B1 SH2B adaptor protein 1 -1.13408
SMG7 SMG7 nonsense mediated mRNA decay factor -1.13143
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.10821
FER fer (fps/fes related) tyrosine kinase -1.10032
CLEC16A C-type lectin domain family 16, member A -1.08608
APLP2 amyloid beta (A4) precursor-like protein 2 -1.08369
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -1.08057
F2R coagulation factor II (thrombin) receptor -1.0692
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -1.05347
SKP1 S-phase kinase-associated protein 1 -1.01712
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.01584
SSB Sjogren syndrome antigen B (autoantigen La) -0.990828
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.987439
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.971164
GPNMB glycoprotein (transmembrane) nmb -0.961976
TGFBR3 transforming growth factor, beta receptor III -0.950547
HSPA2 heat shock 70kDa protein 2 -0.949197
ARF6 ADP-ribosylation factor 6 -0.932213
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.92791
FIG4 FIG4 phosphoinositide 5-phosphatase -0.918129
FAM134C family with sequence similarity 134, member C -0.915614
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.914591
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.882998
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -0.876405
TLK1 tousled-like kinase 1 -0.869752
XBP1 X-box binding protein 1 -0.869572
COL4A5 collagen, type IV, alpha 5 -0.867059
COG7 component of oligomeric golgi complex 7 -0.864092
CREBL2 cAMP responsive element binding protein-like 2 -0.856612
IPO7 importin 7 -0.854361
SRSF3 serine/arginine-rich splicing factor 3 -0.853528
SAP18 Sin3A-associated protein, 18kDa -0.845173
SUB1 SUB1 homolog (S. cerevisiae) -0.844668
EHBP1 EH domain binding protein 1 -0.841183
SART3 squamous cell carcinoma antigen recognized by T cells 3 -0.814394
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -0.810745
CHD9 chromodomain helicase DNA binding protein 9 -0.802317
BRD3 bromodomain containing 3 -0.800936
FAM172A family with sequence similarity 172, member A -0.790738
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.780656
AFAP1 actin filament associated protein 1 -0.780431
LAPTM4B lysosomal protein transmembrane 4 beta -0.766354
BLCAP bladder cancer associated protein -0.766166
GSK3B glycogen synthase kinase 3 beta -0.761487
CLIP3 CAP-GLY domain containing linker protein 3 -0.749471
FOXC1 forkhead box C1 -0.746209
DGCR14 DiGeorge syndrome critical region gene 14 -0.739663
TSPAN8 tetraspanin 8 -0.733735
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.732409
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.730214
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.725507
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.718642
CDK14 cyclin-dependent kinase 14 -0.714949
BTD biotinidase -0.714007
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -0.713929
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.709803
TOP2B topoisomerase (DNA) II beta 180kDa -0.708774
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.706581
AQP3 aquaporin 3 (Gill blood group) -0.705438
BMP2 bone morphogenetic protein 2 -0.705021
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.69971
ASXL1 additional sex combs like transcriptional regulator 1 -0.696014
PARP1 poly (ADP-ribose) polymerase 1 -0.694271
KANK1 KN motif and ankyrin repeat domains 1 -0.693864
COPA coatomer protein complex, subunit alpha -0.690867
C1ORF21 chromosome 1 open reading frame 21 -0.690059
RERE arginine-glutamic acid dipeptide (RE) repeats -0.689929
SBSPON somatomedin B and thrombospondin, type 1 domain containing -0.679198
MXRA7 matrix-remodelling associated 7 -0.677528
TARDBP TAR DNA binding protein -0.67349
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.673155
FN1 fibronectin 1 -0.668991
SUMO2 small ubiquitin-like modifier 2 -0.666277
TSPAN3 tetraspanin 3 -0.662671
SOS2 son of sevenless homolog 2 (Drosophila) -0.662599
GYG1 glycogenin 1 -0.659781
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.6594
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -0.658451
PRDX1 peroxiredoxin 1 -0.65809
TOR1AIP1 torsin A interacting protein 1 -0.653084
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.652769
TMED5 transmembrane emp24 protein transport domain containing 5 -0.652548
KDM4A lysine (K)-specific demethylase 4A -0.649332
TSPYL4 TSPY-like 4 -0.644529
RABGGTB Rab geranylgeranyltransferase, beta subunit -0.639914
TMEM131 transmembrane protein 131 -0.637505
TRAM2 translocation associated membrane protein 2 -0.627208
ACIN1 apoptotic chromatin condensation inducer 1 -0.626513
MAN2A2 mannosidase, alpha, class 2A, member 2 -0.6227
LPIN1 lipin 1 -0.622464
PRRC2B proline-rich coiled-coil 2B -0.621703
TOB1 transducer of ERBB2, 1 -0.621558
HTATSF1 HIV-1 Tat specific factor 1 -0.617516
ZNF264 zinc finger protein 264 -0.614481
SNRPG small nuclear ribonucleoprotein polypeptide G -0.609604
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -0.607294
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.606935
H1FX H1 histone family, member X -0.605491
GMDS GDP-mannose 4,6-dehydratase -0.597572
KLK7 kallikrein-related peptidase 7 -0.595142
MYH9 myosin, heavy chain 9, non-muscle -0.594922
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.59319
FNBP1 formin binding protein 1 -0.592681
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.589653
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.58856
HSPA12A heat shock 70kDa protein 12A -0.588225
TLK2 tousled-like kinase 2 -0.584325
VCL vinculin -0.582334
SEPT7 septin 7 -0.581808
DESI2 desumoylating isopeptidase 2 -0.57796
CLIC5 chloride intracellular channel 5 -0.57414
GDI1 GDP dissociation inhibitor 1 -0.572214
CHD3 chromodomain helicase DNA binding protein 3 -0.57172
HMGN1 high mobility group nucleosome binding domain 1 -0.569682
MAP1B microtubule-associated protein 1B -0.566335
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.564324
GAB2 GRB2-associated binding protein 2 -0.563971
HDAC2 histone deacetylase 2 -0.55702
VTI1B vesicle transport through interaction with t-SNAREs 1B -0.556372
CDC16 cell division cycle 16 -0.554088
TGOLN2 trans-golgi network protein 2 -0.55347
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.551529
HYOU1 hypoxia up-regulated 1 -0.545106
VEGFA vascular endothelial growth factor A -0.542868
PGRMC1 progesterone receptor membrane component 1 -0.540904
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -0.539597
LTBP4 latent transforming growth factor beta binding protein 4 -0.537836
HSPB11 heat shock protein family B (small), member 11 -0.535328
DCAF8 DDB1 and CUL4 associated factor 8 -0.534893
LRP10 low density lipoprotein receptor-related protein 10 -0.530877
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.528349
UBXN2B UBX domain protein 2B -0.524159
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.523119
ZMPSTE24 zinc metallopeptidase STE24 -0.521325
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.520631
EXOC3 exocyst complex component 3 -0.517913
PTPRO protein tyrosine phosphatase, receptor type, O -0.517237
TNNC1 troponin C type 1 (slow) -0.516821
FAT1 FAT atypical cadherin 1 -0.51667
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -0.516448
C11ORF58 chromosome 11 open reading frame 58 -0.515872
TBCB tubulin folding cofactor B -0.509823
MTMR3 myotubularin related protein 3 -0.509595
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.508798
TUBB3 tubulin, beta 3 class III -0.499455
RRAGA Ras-related GTP binding A -0.499225
MME membrane metallo-endopeptidase -0.499072
CIRBP cold inducible RNA binding protein -0.497433
CTNND1 catenin (cadherin-associated protein), delta 1 -0.496567
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.494367
PEX11B peroxisomal biogenesis factor 11 beta -0.493224
STK24 serine/threonine kinase 24 -0.491383
OPTN optineurin -0.491369
F3 coagulation factor III (thromboplastin, tissue factor) -0.490243
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.484636
HMGN4 high mobility group nucleosomal binding domain 4 -0.481734
MFN2 mitofusin 2 -0.480542
ESYT1 extended synaptotagmin-like protein 1 -0.478557
C9ORF3 chromosome 9 open reading frame 3 -0.477331
SUMO1 small ubiquitin-like modifier 1 -0.476775
FZD2 frizzled class receptor 2 -0.475711
TUBB2A tubulin, beta 2A class IIa -0.475237
SMAD1 SMAD family member 1 -0.474706
UBE2S ubiquitin-conjugating enzyme E2S -0.474304
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.473201
DEK DEK proto-oncogene -0.468879
USP33 ubiquitin specific peptidase 33 -0.467478
ZNF207 zinc finger protein 207 -0.466237
FPGT fucose-1-phosphate guanylyltransferase -0.466232
RHOBTB2 Rho-related BTB domain containing 2 -0.465381
TRAPPC8 trafficking protein particle complex 8 -0.4644
FTO fat mass and obesity associated -0.459964
RBBP4 retinoblastoma binding protein 4 -0.459124
VDAC2 voltage-dependent anion channel 2 -0.457017
GLUL glutamate-ammonia ligase -0.456898
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -0.455971
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.455173
DSTN destrin (actin depolymerizing factor) -0.45359
ZBTB20 zinc finger and BTB domain containing 20 -0.453243
NARS asparaginyl-tRNA synthetase -0.452017
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -0.451342
NFE2L1 nuclear factor, erythroid 2-like 1 -0.450986
EIF4A3 eukaryotic translation initiation factor 4A3 -0.450584
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.450257
RPS24 ribosomal protein S24 -0.44859
SRSF10 serine/arginine-rich splicing factor 10 -0.443241
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -0.442286
TPX2 TPX2, microtubule-associated -0.441743
GJA1 gap junction protein, alpha 1, 43kDa -0.44149
DTX4 deltex 4, E3 ubiquitin ligase -0.439562
USP46 ubiquitin specific peptidase 46 -0.439525
LEPROT leptin receptor overlapping transcript -0.43905
MCM6 minichromosome maintenance complex component 6 -0.438561
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.437393
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -0.436977
MXRA8 matrix-remodelling associated 8 -0.434554
PALLD palladin, cytoskeletal associated protein -0.430544
FHL1 four and a half LIM domains 1 -0.430306
TCTA T-cell leukemia translocation altered -0.427687
EID1 EP300 interacting inhibitor of differentiation 1 -0.424049
DDHD2 DDHD domain containing 2 -0.423292
SEPT11 septin 11 -0.422795
FANCL Fanconi anemia, complementation group L -0.422756
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -0.422741
FOXJ2 forkhead box J2 -0.420674
BEX4 brain expressed, X-linked 4 -0.418131
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -0.417264
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.415634
IMMT inner membrane protein, mitochondrial -0.415187
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.415118
TYRO3 TYRO3 protein tyrosine kinase -0.414173
OXSR1 oxidative stress responsive 1 -0.41364
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -0.412996
GANAB glucosidase, alpha; neutral AB -0.412396
SEPT2 septin 2 -0.411702
TCF12 transcription factor 12 -0.411489
TSNAX translin-associated factor X -0.411255
SIX1 SIX homeobox 1 -0.40806
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.407779
NCSTN nicastrin -0.407745
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.407099
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.404996
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.404071
CTBP1 C-terminal binding protein 1 -0.403452
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.403389
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.40153
LOXL1 lysyl oxidase-like 1 -0.398482
PGAM1 phosphoglycerate mutase 1 (brain) -0.397008
PAWR PRKC, apoptosis, WT1, regulator -0.396564
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.395519
LARGE like-glycosyltransferase -0.393559
EIF3M eukaryotic translation initiation factor 3, subunit M -0.392487
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -0.392415
NFASC neurofascin -0.391824
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -0.39145
HOXD1 homeobox D1 -0.391379
FAM20B family with sequence similarity 20, member B -0.390624
PODXL podocalyxin-like -0.389821
SRSF9 serine/arginine-rich splicing factor 9 -0.388977
RNF103 ring finger protein 103 -0.386677
ZNF146 zinc finger protein 146 -0.386408
PKD1 polycystic kidney disease 1 (autosomal dominant) -0.38477
FERMT2 fermitin family member 2 -0.383813
URI1 URI1, prefoldin-like chaperone -0.383537
CFH complement factor H -0.382954
TFDP1 transcription factor Dp-1 -0.381552
KIAA0232 KIAA0232 -0.380934
BCLAF1 BCL2-associated transcription factor 1 -0.380575
MLEC malectin -0.38051
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.379969
MFAP1 microfibrillar-associated protein 1 -0.379908
NCKAP1 NCK-associated protein 1 -0.379546
NPC2 Niemann-Pick disease, type C2 -0.377652
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.37743
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -0.376568
ETF1 eukaryotic translation termination factor 1 -0.376264
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.375129
R3HDM2 R3H domain containing 2 -0.374075
RABGAP1L RAB GTPase activating protein 1-like -0.373582
MYLK myosin light chain kinase -0.371713
FOXD1 forkhead box D1 -0.370556
DAPK1 death-associated protein kinase 1 -0.369852
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -0.366259
TBCA tubulin folding cofactor A -0.366234
RAP1B RAP1B, member of RAS oncogene family -0.365375
CLIP1 CAP-GLY domain containing linker protein 1 -0.365346
IARS isoleucyl-tRNA synthetase -0.363037
MYO1B myosin IB -0.360965
UTRN utrophin -0.360158
METTL3 methyltransferase like 3 -0.360124
NONO non-POU domain containing, octamer-binding -0.358965
BLVRB biliverdin reductase B -0.358918
PSIP1 PC4 and SFRS1 interacting protein 1 -0.357052
ANXA2P1 annexin A2 pseudogene 1 -0.356734
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.355145
DST dystonin -0.354965
ANKRD46 ankyrin repeat domain 46 -0.353928
RNF11 ring finger protein 11 -0.352347
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -0.352214
MEGF9 multiple EGF-like-domains 9 -0.351038
Funding