| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.157001 |
| PODXL | podocalyxin-like | 0.149871 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.127826 |
| B2M | beta-2-microglobulin | 0.121538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105769 |
| NDRG1 | N-myc downstream regulated 1 | 0.10568 |
| LDHA | lactate dehydrogenase A | 0.0996363 |
| LOX | lysyl oxidase | 0.0895465 |
| TMSB10 | thymosin beta 10 | 0.0877429 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0705355 |
| RPL23 | ribosomal protein L23 | 0.0612747 |
| TPM3 | tropomyosin 3 | 0.0586658 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0577199 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0551253 |
| FLNB | filamin B, beta | 0.0540927 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0535536 |
| RACK1 | receptor for activated C kinase 1 | 0.0526706 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0498981 |
| RPS3 | ribosomal protein S3 | 0.0482324 |
| FLNA | filamin A, alpha | 0.0477626 |
| THBS2 | thrombospondin 2 | 0.0476069 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0469073 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0462753 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0423413 |
| STC1 | stanniocalcin 1 | 0.0422729 |
| ENO1 | enolase 1, (alpha) | 0.0422212 |
| KLF6 | Kruppel-like factor 6 | 0.0416268 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0413588 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0403649 |
| ARRDC3 | arrestin domain containing 3 | 0.040309 |
| RPS12 | ribosomal protein S12 | 0.0394034 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0386567 |
| SON | SON DNA binding protein | 0.0383406 |
| PKM | pyruvate kinase, muscle | 0.0379638 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0366553 |
| RPL26 | ribosomal protein L26 | 0.0366243 |
| CD44 | CD44 molecule (Indian blood group) | 0.0364072 |
| PRSS23 | protease, serine, 23 | 0.036043 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0350352 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0341965 |
| TPI1 | triosephosphate isomerase 1 | 0.0338657 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0329232 |
| RPL37A | ribosomal protein L37a | 0.0320728 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0310841 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0308582 |
| TAGLN2 | transgelin 2 | 0.0293831 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0285134 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0284538 |
| RPL12 | ribosomal protein L12 | 0.0282503 |
| S100A11 | S100 calcium binding protein A11 | 0.0281002 |
| RPL3 | ribosomal protein L3 | 0.0276388 |
| FTL | ferritin, light polypeptide | 0.0273994 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0270634 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0269638 |
| YBX1 | Y box binding protein 1 | 0.0268694 |
| RPL11 | ribosomal protein L11 | 0.0265678 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0255448 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0254176 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0251098 |
| SERINC1 | serine incorporator 1 | 0.0249448 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0249332 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0245123 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0244888 |
| L1CAM | L1 cell adhesion molecule | 0.0240322 |
| RPL30 | ribosomal protein L30 | 0.0239603 |
| LOXL2 | lysyl oxidase-like 2 | 0.0238799 |
| EZR | ezrin | 0.0233609 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0230635 |
| SET | SET nuclear proto-oncogene | 0.0227944 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226356 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0224681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0224585 |
| ANXA2 | annexin A2 | 0.0221398 |
| RPL37 | ribosomal protein L37 | 0.0219991 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0218944 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0216957 |
| CSTB | cystatin B (stefin B) | 0.0215253 |
| FAM162A | family with sequence similarity 162, member A | 0.021045 |
| RPS17 | ribosomal protein S17 | 0.0209525 |
| NCKAP1 | NCK-associated protein 1 | 0.0206548 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0204679 |
| RPL4 | ribosomal protein L4 | 0.0202065 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0200722 |
| FSTL1 | follistatin-like 1 | 0.0199618 |
| PLEC | plectin | 0.019759 |
| CAMLG | calcium modulating ligand | 0.0196008 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0195176 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0194805 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0193261 |
| PGK1 | phosphoglycerate kinase 1 | 0.0189941 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0189018 |
| TXNIP | thioredoxin interacting protein | 0.0187644 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0186825 |
| DSPP | dentin sialophosphoprotein | 0.0186226 |
| ADAR | adenosine deaminase, RNA-specific | 0.0185405 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0184089 |
| RPL36 | ribosomal protein L36 | 0.0184003 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0182951 |
| RPS19 | ribosomal protein S19 | 0.0179661 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0179403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.330259 |
| VIM | vimentin | -0.202434 |
| PLAT | plasminogen activator, tissue | -0.11605 |
| CDH13 | cadherin 13 | -0.109218 |
| S100A10 | S100 calcium binding protein A10 | -0.108552 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10583 |
| SLC39A11 | solute carrier family 39, member 11 | -0.091876 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0871958 |
| SUCNR1 | succinate receptor 1 | -0.085201 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0834273 |
| CD99 | CD99 molecule | -0.0820385 |
| CUX1 | cut-like homeobox 1 | -0.081548 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0714949 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0688023 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0636452 |
| AUTS2 | autism susceptibility candidate 2 | -0.0612546 |
| S100A6 | S100 calcium binding protein A6 | -0.058349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0578409 |
| CANX | calnexin | -0.0567833 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0546233 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0515946 |
| NAV1 | neuron navigator 1 | -0.0495734 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0484026 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0435777 |
| RIGI | RNA sensor RIG-I | -0.0428952 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0424948 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0423214 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0413572 |
| HLA-B | major histocompatibility complex, class I, B | -0.0412279 |
| MSI2 | musashi RNA-binding protein 2 | -0.0408469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0397752 |
| COL1A2 | collagen, type I, alpha 2 | -0.03939 |
| ACTG1 | actin gamma 1 | -0.0390556 |
| CALR | calreticulin | -0.0386882 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0383069 |
| MEIS2 | Meis homeobox 2 | -0.0377081 |
| TPM1 | tropomyosin 1 (alpha) | -0.0364252 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0364235 |
| MAP4 | microtubule-associated protein 4 | -0.0362043 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0355934 |
| TAOK1 | TAO kinase 1 | -0.0355051 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0343995 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0339907 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0339184 |
| INSIG1 | insulin induced gene 1 | -0.0337073 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0334206 |
| KRT81 | keratin 81, type II | -0.0330785 |
| ZNF207 | zinc finger protein 207 | -0.0330729 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0327881 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.03261 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0321552 |
| COL5A2 | collagen, type V, alpha 2 | -0.031381 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0312294 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.030978 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0309454 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0308955 |
| FBXO11 | F-box protein 11 | -0.0307829 |
| S100A4 | S100 calcium binding protein A4 | -0.0302784 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0301875 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0297164 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0296926 |
| MT1X | metallothionein 1X | -0.0296602 |
| HIP1 | huntingtin interacting protein 1 | -0.029176 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0289909 |
| C12ORF75 | chromosome 12 open reading frame 75 | -0.0289011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0287851 |
| FRMD4A | FERM domain containing 4A | -0.0287226 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0286372 |
| EFNA5 | ephrin-A5 | -0.0286224 |
| SRPK2 | SRSF protein kinase 2 | -0.028525 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0282386 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0282353 |
| RPS15 | ribosomal protein S15 | -0.0281587 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0280911 |
| MMP12 | matrix metallopeptidase 12 | -0.0280305 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0278749 |
| CCND1 | cyclin D1 | -0.027284 |
| S100A9 | S100 calcium binding protein A9 | -0.0271327 |
| EXOC6B | exocyst complex component 6B | -0.0269148 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0268505 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0268183 |
| LMNA | lamin A/C | -0.0266368 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0263085 |
| RAB10 | RAB10, member RAS oncogene family | -0.0262276 |
| MYO9B | myosin IXB | -0.0257044 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.025691 |
| RPL28 | ribosomal protein L28 | -0.025612 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0252933 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0248243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0247659 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0241991 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0240932 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0239396 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0238076 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0236602 |
| ZNF148 | zinc finger protein 148 | -0.023598 |
| USP34 | ubiquitin specific peptidase 34 | -0.0235204 |
| FNIP1 | folliculin interacting protein 1 | -0.0234559 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0234063 |
| FUS | FUS RNA binding protein | -0.0231581 |
