| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Diammonium Glycyrrhizinate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.20251 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.165975 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.117181 |
| RPL23 | ribosomal protein L23 | 0.103485 |
| TPI1 | triosephosphate isomerase 1 | 0.0957309 |
| RPS12 | ribosomal protein S12 | 0.0930932 |
| RPL3 | ribosomal protein L3 | 0.0887851 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0706894 |
| RACK1 | receptor for activated C kinase 1 | 0.0683101 |
| HMGA2 | high mobility group AT-hook 2 | 0.0675176 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0659871 |
| RPS3 | ribosomal protein S3 | 0.0607236 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0573619 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0551765 |
| TMSB10 | thymosin beta 10 | 0.0543399 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0520962 |
| FTL | ferritin, light polypeptide | 0.0459715 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0435501 |
| INTS6 | integrator complex subunit 6 | 0.0405563 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0401875 |
| RPL11 | ribosomal protein L11 | 0.039033 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0390303 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0388061 |
| ADIPOR2 | adiponectin receptor 2 | 0.0387625 |
| EGR1 | early growth response 1 | 0.0379155 |
| RPL12 | ribosomal protein L12 | 0.0378094 |
| YBX1 | Y box binding protein 1 | 0.0359849 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.035596 |
| EZR | ezrin | 0.0348363 |
| EHBP1 | EH domain binding protein 1 | 0.0346997 |
| RPL26 | ribosomal protein L26 | 0.0345029 |
| RPL4 | ribosomal protein L4 | 0.0344101 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0343724 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0343537 |
| MKI67 | marker of proliferation Ki-67 | 0.032989 |
| AHNAK | AHNAK nucleoprotein | 0.032805 |
| ASPH | aspartate beta-hydroxylase | 0.0320837 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0317823 |
| TPM3 | tropomyosin 3 | 0.0312848 |
| SON | SON DNA binding protein | 0.0302736 |
| RPS17 | ribosomal protein S17 | 0.0297365 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0296279 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0289428 |
| UBC | ubiquitin C | 0.0288436 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0279431 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0278758 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0273206 |
| RPL7 | ribosomal protein L7 | 0.0273156 |
| LDHA | lactate dehydrogenase A | 0.0271682 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0269929 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0265717 |
| FLNA | filamin A, alpha | 0.0265021 |
| RPL37 | ribosomal protein L37 | 0.0262113 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0259675 |
| RPL21 | ribosomal protein L21 | 0.0254193 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249728 |
| STIP1 | stress-induced phosphoprotein 1 | 0.024842 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0246794 |
| GOLGB1 | golgin B1 | 0.024558 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0245044 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0244939 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0243258 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0242548 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.024172 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0241713 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0238193 |
| RPS4X | ribosomal protein S4, X-linked | 0.0232444 |
| CTBP2 | C-terminal binding protein 2 | 0.0232318 |
| HDLBP | high density lipoprotein binding protein | 0.0231516 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0230025 |
| BRD2 | bromodomain containing 2 | 0.0229244 |
| ANXA1 | annexin A1 | 0.0227364 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0227151 |
| FNIP1 | folliculin interacting protein 1 | 0.02258 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.02234 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0221636 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0220301 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0220211 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0218292 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0218016 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0217826 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0213955 |
| HLA-A | major histocompatibility complex, class I, A | 0.0208542 |
| RPL18 | ribosomal protein L18 | 0.0207261 |
| PRDX1 | peroxiredoxin 1 | 0.0204773 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0203738 |
| H1-5 | H1.5 linker histone, cluster member | 0.0203542 |
| RPS2 | ribosomal protein S2 | 0.0202875 |
| DENND5A | DENN/MADD domain containing 5A | 0.0202383 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0202059 |
| DUSP16 | dual specificity phosphatase 16 | 0.0199275 |
| DTNA | dystrobrevin, alpha | 0.0198167 |
| H1-0 | H1.0 linker histone | 0.0194875 |
| CLDND1 | claudin domain containing 1 | 0.0194376 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0194352 |
| LRRC23 | leucine rich repeat containing 23 | 0.0193806 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0191643 |
| PCDH9 | protocadherin 9 | 0.0189874 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0189154 |
| RPS7 | ribosomal protein S7 | 0.0188539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.191744 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.170623 |
| NLGN1 | neuroligin 1 | -0.166488 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.112177 |
| TMEM41B | transmembrane protein 41B | -0.0883567 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0872612 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0745907 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0742887 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0615378 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.058815 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0558273 |
| EDARADD | EDAR-associated death domain | -0.0556999 |
| MMP12 | matrix metallopeptidase 12 | -0.0546185 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0537026 |
| RTN4 | reticulon 4 | -0.0528274 |
| JMJD1C | jumonji domain containing 1C | -0.052647 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0503048 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0498871 |
| CENPF | centromere protein F, 350/400kDa | -0.0480559 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0473578 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0470209 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0466667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0454104 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0434792 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0425633 |
| RPS21 | ribosomal protein S21 | -0.042222 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0418393 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0408451 |
| KIF18B | kinesin family member 18B | -0.0402801 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0394795 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0391947 |
| TENM3 | teneurin transmembrane protein 3 | -0.0389653 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0385788 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0377491 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0370439 |
| PRR11 | proline rich 11 | -0.036437 |
| VMP1 | vacuole membrane protein 1 | -0.0358427 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0356773 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0355488 |
| RPL35A | ribosomal protein L35a | -0.0354541 |
| MIS18BP1 | MIS18 binding protein 1 | -0.035152 |
| RPL38 | ribosomal protein L38 | -0.0340536 |
| DST | dystonin | -0.0334975 |
| LMO7 | LIM domain 7 | -0.032243 |
| RPLP2 | ribosomal protein, large, P2 | -0.0321911 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0321723 |
| XPO1 | exportin 1 | -0.0320982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0317624 |
| ZNF804A | zinc finger protein 804A | -0.0312785 |
| VCL | vinculin | -0.0311992 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0308123 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0307872 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0307769 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0306939 |
| NHSL1 | NHS-like 1 | -0.0306012 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0305184 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0301095 |
| WDR43 | WD repeat domain 43 | -0.0293463 |
| VIM | vimentin | -0.0293149 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0290993 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0289039 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0286452 |
| ACTG1 | actin gamma 1 | -0.0284107 |
| CCDC88A | coiled-coil domain containing 88A | -0.0281581 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.028078 |
| TMEM131 | transmembrane protein 131 | -0.0280471 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0280023 |
| CENPE | centromere protein E, 312kDa | -0.0278461 |
| TMEM123 | transmembrane protein 123 | -0.0276603 |
| PDGFC | platelet derived growth factor C | -0.0272569 |
| NEK7 | NIMA-related kinase 7 | -0.0271215 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0270876 |
| CDK17 | cyclin-dependent kinase 17 | -0.0270658 |
| RBMX | RNA binding motif protein, X-linked | -0.0269106 |
| TNPO1 | transportin 1 | -0.0267242 |
| FBXO11 | F-box protein 11 | -0.0264756 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0264257 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0259523 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0258951 |
| TUBB6 | tubulin, beta 6 class V | -0.0258836 |
| FUS | FUS RNA binding protein | -0.0257536 |
| RASAL2 | RAS protein activator like 2 | -0.0256997 |
| SEPTIN7 | septin 7 | -0.0253952 |
| KLHL24 | kelch-like family member 24 | -0.0253886 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0252951 |
| OXR1 | oxidation resistance 1 | -0.0251859 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0251661 |
| RPS15 | ribosomal protein S15 | -0.0249161 |
| TUBA1B | tubulin, alpha 1b | -0.0249113 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0249009 |
| DEK | DEK proto-oncogene | -0.0248966 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.02486 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0248164 |
| MPG | N-methylpurine-DNA glycosylase | -0.0245782 |
| RBM25 | RNA binding motif protein 25 | -0.0239968 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0238585 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0238314 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0238042 |
| USP34 | ubiquitin specific peptidase 34 | -0.0237492 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0236749 |
