| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Diammonium Glycyrrhizinate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.126847 |
| CEP250 | centrosomal protein 250kDa | 0.108968 |
| CDK12 | cyclin-dependent kinase 12 | 0.107165 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0849886 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0716115 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0706754 |
| LASP1 | LIM and SH3 protein 1 | 0.070664 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0648155 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0648147 |
| INTS6 | integrator complex subunit 6 | 0.0645459 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0643652 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0626031 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.062072 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0602171 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0587469 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0587381 |
| VCP | valosin containing protein | 0.0582581 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0581128 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0580808 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0579604 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0568816 |
| PTK2 | protein tyrosine kinase 2 | 0.0564228 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0542776 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0527355 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0523178 |
| VMP1 | vacuole membrane protein 1 | 0.050778 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0481863 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0474764 |
| DENND1A | DENN/MADD domain containing 1A | 0.0472067 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0471939 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.045577 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0445393 |
| RBM47 | RNA binding motif protein 47 | 0.0440233 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0437433 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0423493 |
| EFNA5 | ephrin-A5 | 0.0415576 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0412845 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0404837 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0401396 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0400236 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0397658 |
| ACTG1 | actin gamma 1 | 0.0388839 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0388147 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0385344 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.038259 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0382219 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0381699 |
| MSI2 | musashi RNA-binding protein 2 | 0.0377981 |
| PTMA | prothymosin, alpha | 0.0377494 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0376288 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0375333 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0372726 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0348052 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0345182 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0343856 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0341916 |
| CDK13 | cyclin-dependent kinase 13 | 0.0341874 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.033874 |
| SMYD3 | SET and MYND domain containing 3 | 0.0336134 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0333535 |
| PARD3 | par-3 family cell polarity regulator | 0.0330541 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0330225 |
| DTNA | dystrobrevin, alpha | 0.0329333 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0329247 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0327684 |
| SP100 | SP100 nuclear antigen | 0.0325594 |
| VCL | vinculin | 0.0320714 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0317782 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0316053 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0315297 |
| RAD51B | RAD51 paralog B | 0.0312823 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0312797 |
| YAP1 | Yes-associated protein 1 | 0.0311496 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0310653 |
| TNS3 | tensin 3 | 0.0310311 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0310108 |
| MCL1 | myeloid cell leukemia 1 | 0.0307632 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.030609 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0306064 |
| AHNAK | AHNAK nucleoprotein | 0.03051 |
| EXOC4 | exocyst complex component 4 | 0.0304959 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0301855 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0301666 |
| RCOR1 | REST corepressor 1 | 0.0296718 |
| CUX1 | cut-like homeobox 1 | 0.0296131 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0293624 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0293452 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.029248 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0291759 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0291575 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0291222 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0287393 |
| ENAH | enabled homolog (Drosophila) | 0.0287301 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0287188 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0279862 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0275594 |
| PRKCA | protein kinase C, alpha | 0.0271849 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0268966 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0264213 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0263013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.0782576 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0613 |
| MT2A | metallothionein 2A | -0.0605424 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0481217 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.042596 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0346153 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0344746 |
| TMEM165 | transmembrane protein 165 | -0.0336203 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0324413 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0315689 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0282754 |
| TSC22D2 | TSC22 domain family, member 2 | -0.027223 |
| S100A8 | S100 calcium binding protein A8 | -0.0268649 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0257863 |
| AREG | amphiregulin | -0.0251163 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0241001 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0238253 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0237484 |
| LDHA | lactate dehydrogenase A | -0.0235963 |
| S100A14 | S100 calcium binding protein A14 | -0.0231602 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0230474 |
| CCNI | cyclin I | -0.0229448 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0210316 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0204723 |
| PERP | PERP, TP53 apoptosis effector | -0.0204342 |
| TXNRD1 | thioredoxin reductase 1 | -0.0202172 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.019918 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0196657 |
| OSMR | oncostatin M receptor | -0.0195088 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0184768 |
| B2M | beta-2-microglobulin | -0.0184565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0183264 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0182292 |
| KLF6 | Kruppel-like factor 6 | -0.0178272 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.017355 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0166723 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.016634 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0164009 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0162634 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0161722 |
| DUSP6 | dual specificity phosphatase 6 | -0.0159124 |
| SERINC3 | serine incorporator 3 | -0.0155648 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0153461 |
| S100A9 | S100 calcium binding protein A9 | -0.015329 |
| SDC4 | syndecan 4 | -0.0151747 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0149411 |
| CFB | complement factor B | -0.0147631 |
| SON | SON DNA binding protein | -0.0146548 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0142704 |
| TMC5 | transmembrane channel-like 5 | -0.0142355 |
| S100A7 | S100 calcium binding protein A7 | -0.01419 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0135049 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0133603 |
| RTN4 | reticulon 4 | -0.0133478 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0133117 |
| SQOR | sulfide quinone oxidoreductase | -0.0131609 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0130836 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.013014 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.01293 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0128487 |
| RPL18 | ribosomal protein L18 | -0.0125964 |
| FTL | ferritin, light polypeptide | -0.0125625 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0124976 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0124314 |
| TBK1 | TANK-binding kinase 1 | -0.012381 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0122641 |
| GATA3 | GATA binding protein 3 | -0.0122605 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0120924 |
| MT1X | metallothionein 1X | -0.0120621 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0120119 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0117422 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.011681 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0116803 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0116412 |
| MAP1B | microtubule-associated protein 1B | -0.0114966 |
| YBX3 | Y box binding protein 3 | -0.0113584 |
| ANKRD12 | ankyrin repeat domain 12 | -0.01131 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | -0.0112853 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.011258 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0112285 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0111423 |
| CHMP2B | charged multivesicular body protein 2B | -0.0111214 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0111006 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0110899 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0110375 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0109686 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.0109029 |
| HRNR | hornerin | -0.0108117 |
| RACK1 | receptor for activated C kinase 1 | -0.0108044 |
| ZFP36 | ZFP36 ring finger protein | -0.0106446 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0105289 |
| ABHD17C | abhydrolase domain containing 17C | -0.0105121 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0104877 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0104765 |
| TXNIP | thioredoxin interacting protein | -0.0103886 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0103323 |
| TC2N | tandem C2 domains, nuclear | -0.0103312 |
| KITLG | KIT ligand | -0.0103101 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0103073 |
| UBXN4 | UBX domain protein 4 | -0.0102975 |
