| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.166119 |
| NDRG1 | N-myc downstream regulated 1 | 0.14479 |
| GPC6 | glypican 6 | 0.130864 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.12559 |
| NLGN1 | neuroligin 1 | 0.116593 |
| VIM | vimentin | 0.113275 |
| MT2A | metallothionein 2A | 0.108472 |
| TMSB10 | thymosin beta 10 | 0.10487 |
| ENO1 | enolase 1, (alpha) | 0.0957294 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0947874 |
| VGF | VGF nerve growth factor inducible | 0.0942487 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0874683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0867032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0833604 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0766375 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0752586 |
| ASPH | aspartate beta-hydroxylase | 0.0709081 |
| CENPF | centromere protein F, 350/400kDa | 0.0691132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0655769 |
| CD109 | CD109 molecule | 0.065147 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0615601 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0606846 |
| TAGLN2 | transgelin 2 | 0.0590982 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0589739 |
| B2M | beta-2-microglobulin | 0.0560143 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.054982 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0547336 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0546072 |
| PTK2 | protein tyrosine kinase 2 | 0.0526351 |
| PKM | pyruvate kinase, muscle | 0.0525981 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0523713 |
| PCDH7 | protocadherin 7 | 0.0510931 |
| CTTNBP2 | cortactin binding protein 2 | 0.0508779 |
| PLIN2 | perilipin 2 | 0.0493852 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0491594 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0461646 |
| TPI1 | triosephosphate isomerase 1 | 0.0459311 |
| FMNL2 | formin-like 2 | 0.0453635 |
| RPL37A | ribosomal protein L37a | 0.0452741 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0448051 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0445988 |
| HLA-B | major histocompatibility complex, class I, B | 0.0440994 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0404208 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0393711 |
| PRELID2 | PRELI domain containing 2 | 0.0383463 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0379293 |
| PHF21A | PHD finger protein 21A | 0.037894 |
| RPS12 | ribosomal protein S12 | 0.0378353 |
| LDHA | lactate dehydrogenase A | 0.0374025 |
| FTL | ferritin, light polypeptide | 0.0369149 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0367814 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0365997 |
| ZNF638 | zinc finger protein 638 | 0.0360006 |
| PGK1 | phosphoglycerate kinase 1 | 0.0350137 |
| GDF15 | growth differentiation factor 15 | 0.0336599 |
| RPL3 | ribosomal protein L3 | 0.0334532 |
| HLA-A | major histocompatibility complex, class I, A | 0.0331122 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0326152 |
| ADM | adrenomedullin | 0.0324867 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0320925 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0320504 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0320386 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0314077 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0313265 |
| RPS19 | ribosomal protein S19 | 0.0311888 |
| MEF2A | myocyte enhancer factor 2A | 0.031067 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0307173 |
| RPL23 | ribosomal protein L23 | 0.0306227 |
| RPS3 | ribosomal protein S3 | 0.0304256 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303144 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0302353 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0299667 |
| RPL12 | ribosomal protein L12 | 0.0296944 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0295612 |
| NBAS | neuroblastoma amplified sequence | 0.0294238 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0291047 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0288721 |
| POTEF | POTE ankyrin domain family, member F | 0.028751 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0285641 |
| PARVB | parvin, beta | 0.0282803 |
| PTMA | prothymosin, alpha | 0.0278571 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0275557 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0274596 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0272462 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.02706 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0267714 |
| ZNF704 | zinc finger protein 704 | 0.0267185 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0266313 |
| HOMER1 | homer scaffolding protein 1 | 0.0262564 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0258557 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0256388 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.025619 |
| FAM162A | family with sequence similarity 162, member A | 0.0254945 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.025065 |
| CALD1 | caldesmon 1 | 0.0247286 |
| ATXN1 | ataxin 1 | 0.0246256 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0245072 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0243518 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0242352 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0242077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.217619 |
| FMN1 | formin 1 | -0.130099 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0978318 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0640055 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.062895 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0619234 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0616083 |
| VCL | vinculin | -0.0575811 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0522295 |
| PI15 | peptidase inhibitor 15 | -0.051483 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0513619 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0462475 |
| RTN4 | reticulon 4 | -0.0428775 |
| TNNC1 | troponin C type 1 (slow) | -0.0396551 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0395561 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0350552 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0349737 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0334066 |
| RHOJ | ras homolog family member J | -0.033 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0325786 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0325459 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0315089 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0312798 |
| SRPK2 | SRSF protein kinase 2 | -0.0299355 |
| MITF | microphthalmia-associated transcription factor | -0.0295415 |
| CDC73 | cell division cycle 73 | -0.0289026 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0286393 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0277225 |
| ACTG1 | actin gamma 1 | -0.0275184 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0275036 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0272866 |
| RBM33 | RNA binding motif protein 33 | -0.0270249 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0257386 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.025589 |
| PDLIM5 | PDZ and LIM domain 5 | -0.02555 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0255327 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245891 |
| CDH19 | cadherin 19, type 2 | -0.0245581 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0241711 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0240538 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0239103 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0235926 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0234454 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0234296 |
| APP | amyloid beta (A4) precursor protein | -0.0234276 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0231315 |
| RBM39 | RNA binding motif protein 39 | -0.0229798 |
| MRTFA | myocardin related transcription factor A | -0.0227459 |
| MED13L | mediator complex subunit 13-like | -0.0227139 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0225059 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | -0.0215692 |
| LIMA1 | LIM domain and actin binding 1 | -0.0213936 |
| ATF6 | activating transcription factor 6 | -0.0205895 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.020287 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0199897 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0198733 |
| A2M | alpha-2-macroglobulin | -0.0198004 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0197692 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0194724 |
| NEK7 | NIMA-related kinase 7 | -0.0194182 |
| IER3 | immediate early response 3 | -0.0193886 |
| USP53 | ubiquitin specific peptidase 53 | -0.0188673 |
| HMCN1 | hemicentin 1 | -0.0188622 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0187161 |
| HBP1 | HMG-box transcription factor 1 | -0.0185467 |
| AHR | aryl hydrocarbon receptor | -0.0185314 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0184049 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0183573 |
| TMEM168 | transmembrane protein 168 | -0.0183469 |
| FUS | FUS RNA binding protein | -0.0183025 |
| PDE10A | phosphodiesterase 10A | -0.0180362 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0179164 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0176827 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0174056 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0173774 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0173048 |
| DUSP6 | dual specificity phosphatase 6 | -0.0172387 |
| FHL2 | four and a half LIM domains 2 | -0.0171595 |
| DMD | dystrophin | -0.0171044 |
| VMP1 | vacuole membrane protein 1 | -0.0170038 |
| FBXO11 | F-box protein 11 | -0.0169072 |
| COG5 | component of oligomeric golgi complex 5 | -0.0167219 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0167008 |
| JMJD1C | jumonji domain containing 1C | -0.0165508 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0165498 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0165364 |
| ZNF644 | zinc finger protein 644 | -0.0165198 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0164029 |
| TRIB1 | tribbles pseudokinase 1 | -0.0164024 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0163404 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0163073 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0162418 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0162361 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0161032 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.016012 |
| TCF12 | transcription factor 12 | -0.0158874 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0157623 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0156544 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0154481 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0153962 |
