| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.126485 |
| NDRG1 | N-myc downstream regulated 1 | 0.1202 |
| MT2A | metallothionein 2A | 0.095753 |
| RPL23 | ribosomal protein L23 | 0.0875333 |
| RPL3 | ribosomal protein L3 | 0.0851396 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0805047 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0783732 |
| RACK1 | receptor for activated C kinase 1 | 0.0762363 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0713991 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0712194 |
| RPS12 | ribosomal protein S12 | 0.0690408 |
| FTL | ferritin, light polypeptide | 0.0665685 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0553763 |
| RPS3 | ribosomal protein S3 | 0.0547352 |
| TPI1 | triosephosphate isomerase 1 | 0.0503456 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0484704 |
| TMSB10 | thymosin beta 10 | 0.0477504 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0444789 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0417449 |
| RPL26 | ribosomal protein L26 | 0.0411058 |
| RPS17 | ribosomal protein S17 | 0.0410405 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0410075 |
| ARRDC3 | arrestin domain containing 3 | 0.0407075 |
| B2M | beta-2-microglobulin | 0.0398792 |
| RPL18 | ribosomal protein L18 | 0.0388979 |
| YBX1 | Y box binding protein 1 | 0.0382559 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0381964 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0381074 |
| TPM3 | tropomyosin 3 | 0.0378122 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0371823 |
| PCBP2 | poly(rC) binding protein 2 | 0.0367124 |
| HLA-A | major histocompatibility complex, class I, A | 0.0365302 |
| PLEC | plectin | 0.0358889 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0348105 |
| RPL21 | ribosomal protein L21 | 0.0332615 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0332493 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0326771 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0320816 |
| RPS4X | ribosomal protein S4, X-linked | 0.0311986 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0311066 |
| GPX4 | glutathione peroxidase 4 | 0.0302516 |
| HELZ | helicase with zinc finger | 0.030215 |
| RPL36 | ribosomal protein L36 | 0.0300785 |
| SON | SON DNA binding protein | 0.0297819 |
| RPL4 | ribosomal protein L4 | 0.0297488 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0295509 |
| VIM | vimentin | 0.0285262 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.028254 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0280471 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0279083 |
| ZNF638 | zinc finger protein 638 | 0.0278401 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0273814 |
| PFKP | phosphofructokinase, platelet | 0.0273577 |
| NUP58 | nucleoporin 58 | 0.0273174 |
| HMGA1 | high mobility group AT-hook 1 | 0.0270855 |
| FLNB | filamin B, beta | 0.0268242 |
| PRELID2 | PRELI domain containing 2 | 0.0266526 |
| RPL12 | ribosomal protein L12 | 0.0264663 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0261804 |
| ZNF292 | zinc finger protein 292 | 0.0261643 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0259943 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0253572 |
| RPL31 | ribosomal protein L31 | 0.0246699 |
| ARCN1 | archain 1 | 0.0240688 |
| RPS27 | ribosomal protein S27 | 0.0239323 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.023794 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0236891 |
| RPS26 | ribosomal protein S26 | 0.0236739 |
| TFG | TRK-fused gene | 0.0232965 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0231968 |
| LDHA | lactate dehydrogenase A | 0.0229922 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0228383 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0227418 |
| VEGFA | vascular endothelial growth factor A | 0.0226268 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0223139 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0222709 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.022218 |
| INSIG2 | insulin induced gene 2 | 0.0221894 |
| PNN | pinin, desmosome associated protein | 0.0218917 |
| FN1 | fibronectin 1 | 0.0212496 |
| CHMP5 | charged multivesicular body protein 5 | 0.0212345 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0210996 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0210296 |
| YEATS2 | YEATS domain containing 2 | 0.020903 |
| HYOU1 | hypoxia up-regulated 1 | 0.0206356 |
| FAM120A | family with sequence similarity 120A | 0.0205855 |
| SEPTIN9 | septin 9 | 0.0203813 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0202645 |
| HSPA8 | heat shock 70kDa protein 8 | 0.020234 |
| SSRP1 | structure specific recognition protein 1 | 0.0201592 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0201473 |
| TAPBP | TAP binding protein (tapasin) | 0.0200452 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0200036 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0199576 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0194941 |
| ZFP36 | ZFP36 ring finger protein | 0.0194142 |
| RPS19 | ribosomal protein S19 | 0.0193806 |
| MYO1B | myosin IB | 0.0193097 |
| HDLBP | high density lipoprotein binding protein | 0.0192551 |
| SET | SET nuclear proto-oncogene | 0.0191326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160487 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.159839 |
| PTMA | prothymosin, alpha | -0.115476 |
| FAT1 | FAT atypical cadherin 1 | -0.108914 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.102994 |
| TPM4 | tropomyosin 4 | -0.0879273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0873485 |
| ACTG1 | actin gamma 1 | -0.0835295 |
| S100A10 | S100 calcium binding protein A10 | -0.071766 |
| RPS24 | ribosomal protein S24 | -0.0694246 |
| FRMD5 | FERM domain containing 5 | -0.0675459 |
| RPS15 | ribosomal protein S15 | -0.0614169 |
| FHIT | fragile histidine triad | -0.0595538 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0591726 |
| JMJD1C | jumonji domain containing 1C | -0.0569907 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0558697 |
| SMYD3 | SET and MYND domain containing 3 | -0.0554459 |
| NF1 | neurofibromin 1 | -0.052604 |
| GLG1 | golgi glycoprotein 1 | -0.051331 |
| RPL35A | ribosomal protein L35a | -0.0512437 |
| TENM3 | teneurin transmembrane protein 3 | -0.0494468 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.049262 |
| MKI67 | marker of proliferation Ki-67 | -0.0477314 |
| CADPS | Ca++-dependent secretion activator | -0.045833 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0446354 |
| RPL38 | ribosomal protein L38 | -0.0445782 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.043691 |
| CD2AP | CD2-associated protein | -0.0436531 |
| RPLP2 | ribosomal protein, large, P2 | -0.0434471 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.043085 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0429932 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0422661 |
| RAD51B | RAD51 paralog B | -0.0407476 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0407087 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0404875 |
| RPS25 | ribosomal protein S25 | -0.0401433 |
| SERINC5 | serine incorporator 5 | -0.0401404 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0401034 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.040033 |
| RPL34 | ribosomal protein L34 | -0.0392098 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0391703 |
| RPS21 | ribosomal protein S21 | -0.0385571 |
| KRT8 | keratin 8, type II | -0.0381183 |
| MYO9A | myosin IXA | -0.0379111 |
| RPLP0 | ribosomal protein, large, P0 | -0.0378167 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0375141 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.03742 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0373996 |
| VCL | vinculin | -0.0373198 |
| CENPF | centromere protein F, 350/400kDa | -0.0372785 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0372312 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0371671 |
| EXOC4 | exocyst complex component 4 | -0.0368992 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0366952 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.036541 |
| RPS13 | ribosomal protein S13 | -0.0357283 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0356652 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0355329 |
| WWOX | WW domain containing oxidoreductase | -0.0350349 |
| MSI2 | musashi RNA-binding protein 2 | -0.0347952 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0346017 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0345584 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0345583 |
| TUBA1B | tubulin, alpha 1b | -0.0344874 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.03448 |
| KRT18 | keratin 18, type I | -0.0341249 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0338976 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0336569 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0333264 |
| SDC4 | syndecan 4 | -0.0333147 |
| MED13L | mediator complex subunit 13-like | -0.0330781 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0330643 |
| CCND1 | cyclin D1 | -0.0330276 |
| TCF12 | transcription factor 12 | -0.0329741 |
| FUS | FUS RNA binding protein | -0.0326519 |
| RPL7A | ribosomal protein L7a | -0.0326398 |
| HMGA2 | high mobility group AT-hook 2 | -0.0325043 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0315679 |
| ACTN4 | actinin, alpha 4 | -0.031175 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0311445 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0307752 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0306412 |
| AHNAK | AHNAK nucleoprotein | -0.030539 |
| ZNF644 | zinc finger protein 644 | -0.030443 |
| ANXA2 | annexin A2 | -0.0297284 |
| S100A6 | S100 calcium binding protein A6 | -0.0296867 |
| DIAPH2 | diaphanous-related formin 2 | -0.0295828 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0295735 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0293585 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0293537 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0292995 |
| PTK2 | protein tyrosine kinase 2 | -0.0291369 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0289479 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0288076 |
| FAM193A | family with sequence similarity 193, member A | -0.0285253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0283027 |
| MED13 | mediator complex subunit 13 | -0.0281946 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0281598 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0278749 |
| PDE8A | phosphodiesterase 8A | -0.0278617 |
