| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.221639 |
| MT2A | metallothionein 2A | 0.209001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0945684 |
| TMSB10 | thymosin beta 10 | 0.0893949 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.077586 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0720504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0579946 |
| RPL23 | ribosomal protein L23 | 0.0573523 |
| STC1 | stanniocalcin 1 | 0.0526762 |
| RACK1 | receptor for activated C kinase 1 | 0.0523292 |
| B2M | beta-2-microglobulin | 0.0480165 |
| CADM1 | cell adhesion molecule 1 | 0.0472572 |
| RPS12 | ribosomal protein S12 | 0.0461204 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.045399 |
| RPL11 | ribosomal protein L11 | 0.0443316 |
| RPS3 | ribosomal protein S3 | 0.0432184 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0423201 |
| RPS19 | ribosomal protein S19 | 0.0420973 |
| ARRDC3 | arrestin domain containing 3 | 0.0417858 |
| RPL3 | ribosomal protein L3 | 0.0412615 |
| FTL | ferritin, light polypeptide | 0.0387257 |
| RPS8 | ribosomal protein S8 | 0.0374725 |
| RPL7 | ribosomal protein L7 | 0.0374288 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.037266 |
| RPL37A | ribosomal protein L37a | 0.0363734 |
| LOXL2 | lysyl oxidase-like 2 | 0.0358624 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0357731 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0354585 |
| YBX1 | Y box binding protein 1 | 0.0354411 |
| RPS6 | ribosomal protein S6 | 0.0346456 |
| PTMA | prothymosin, alpha | 0.0332739 |
| RPL18 | ribosomal protein L18 | 0.0328735 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0323762 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0316901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0316593 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0316282 |
| RPL26 | ribosomal protein L26 | 0.0304268 |
| CALR | calreticulin | 0.0303496 |
| VEGFA | vascular endothelial growth factor A | 0.0300125 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0295647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0289098 |
| RPL12 | ribosomal protein L12 | 0.0288003 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0287834 |
| RPL36 | ribosomal protein L36 | 0.0278916 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0276903 |
| GOLGA4 | golgin A4 | 0.0270235 |
| RPL5 | ribosomal protein L5 | 0.0266628 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0264611 |
| RPL30 | ribosomal protein L30 | 0.0259439 |
| HYOU1 | hypoxia up-regulated 1 | 0.0256367 |
| PLEC | plectin | 0.0255793 |
| HLA-A | major histocompatibility complex, class I, A | 0.025367 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0252972 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0239772 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0238489 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0238223 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0237367 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.02365 |
| RPL8 | ribosomal protein L8 | 0.0236322 |
| RPL19 | ribosomal protein L19 | 0.0225318 |
| TPI1 | triosephosphate isomerase 1 | 0.0220046 |
| LDHA | lactate dehydrogenase A | 0.0219778 |
| RPS17 | ribosomal protein S17 | 0.0215967 |
| SPAG9 | sperm associated antigen 9 | 0.0215282 |
| RPL13A | ribosomal protein L13a | 0.0214185 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0213965 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0211613 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0209197 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0207169 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0206625 |
| ADM | adrenomedullin | 0.0206195 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0205383 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0200561 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0198766 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0197787 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0193593 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0192164 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.019111 |
| RPL37 | ribosomal protein L37 | 0.0187616 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0187485 |
| UBC | ubiquitin C | 0.018699 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0184709 |
| RPS14 | ribosomal protein S14 | 0.0183897 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0183833 |
| NAV2 | neuron navigator 2 | 0.0183598 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0182684 |
| PCBP2 | poly(rC) binding protein 2 | 0.0182233 |
| RPLP1 | ribosomal protein, large, P1 | 0.0182052 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0181714 |
| RPL9 | ribosomal protein L9 | 0.0181492 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.017744 |
| MLF1 | myeloid leukemia factor 1 | 0.0176712 |
| RLF | rearranged L-myc fusion | 0.017516 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0174272 |
| SMAD3 | SMAD family member 3 | 0.0174127 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0172756 |
| LOC112694756 | uncharaterized LOC112694756 | 0.01718 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0171119 |
| RPL31 | ribosomal protein L31 | 0.0170984 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0170641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.193615 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.111464 |
| COL1A2 | collagen, type I, alpha 2 | -0.109742 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.106025 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0988493 |
| FN1 | fibronectin 1 | -0.0847226 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0831797 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0814142 |
| CALD1 | caldesmon 1 | -0.0626919 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0619656 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0603433 |
| ASPH | aspartate beta-hydroxylase | -0.0602482 |
| CDH13 | cadherin 13 | -0.0574164 |
| GLIS3 | GLIS family zinc finger 3 | -0.0562413 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0518765 |
| VCAN | versican | -0.0503981 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0470774 |
| VCL | vinculin | -0.0437815 |
| FBN1 | fibrillin 1 | -0.0431158 |
| CNTN5 | contactin 5 | -0.0414176 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0413277 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0394716 |
| TPM4 | tropomyosin 4 | -0.0380798 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0376613 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0376225 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0356882 |
| NAV1 | neuron navigator 1 | -0.0348223 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0347577 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.033625 |
| ACTG1 | actin gamma 1 | -0.0326984 |
| DST | dystonin | -0.0324633 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0317146 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0271533 |
| OSMR | oncostatin M receptor | -0.0270649 |
| IL6ST | interleukin 6 signal transducer | -0.0268543 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0267977 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0267901 |
| COL5A1 | collagen, type V, alpha 1 | -0.0262149 |
| CD44 | CD44 molecule (Indian blood group) | -0.0257157 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0256779 |
| MAP1B | microtubule-associated protein 1B | -0.0254758 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0253747 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0251782 |
| FOXP1 | forkhead box P1 | -0.0251617 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0251576 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0249914 |
| ATXN1 | ataxin 1 | -0.024717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0244667 |
| CUX1 | cut-like homeobox 1 | -0.0241587 |
| NREP | neuronal regeneration related protein | -0.0240435 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0238732 |
| PALLD | palladin, cytoskeletal associated protein | -0.0234304 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.02328 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.023219 |
| SDC2 | syndecan 2 | -0.0229943 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223647 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0220278 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0215701 |
| FRMD4A | FERM domain containing 4A | -0.0215478 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0215458 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0212193 |
| HDAC9 | histone deacetylase 9 | -0.0207317 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0206984 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0206923 |
| NEK10 | NIMA-related kinase 10 | -0.0205593 |
| INHBA | inhibin, beta A | -0.0204546 |
| PRRX1 | paired related homeobox 1 | -0.0203806 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0193599 |
| TENM3 | teneurin transmembrane protein 3 | -0.0190407 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0188737 |
| RUNX1 | runt-related transcription factor 1 | -0.0188619 |
| NRP1 | neuropilin 1 | -0.0188215 |
| EBF1 | early B-cell factor 1 | -0.0188175 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0187502 |
| TPM1 | tropomyosin 1 (alpha) | -0.0186532 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0186032 |
| PRELID2 | PRELI domain containing 2 | -0.0183023 |
| STK38L | serine/threonine kinase 38 like | -0.0181573 |
| HMCN1 | hemicentin 1 | -0.018115 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0181076 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0176226 |
| ZNF644 | zinc finger protein 644 | -0.0175906 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0173299 |
| PXDN | peroxidasin | -0.0173219 |
| RASAL2 | RAS protein activator like 2 | -0.0166101 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0165475 |
| PRSS23 | protease, serine, 23 | -0.0164978 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0163336 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0162457 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0159163 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0158653 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0158117 |
| CPQ | carboxypeptidase Q | -0.0155881 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0152855 |
| NAV3 | neuron navigator 3 | -0.0152536 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0152339 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0152105 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0148247 |
| BNC2 | basonuclin 2 | -0.0147295 |
| LMO4 | LIM domain only 4 | -0.0142882 |
