Diammonium Glycyrrhizinate_HT-29 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Diammonium Glycyrrhizinate perturbation in HT-29 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Diammonium Glycyrrhizinate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NDRG1 N-myc downstream regulated 1 0.149927
LYZ lysozyme 0.115034
LOC102724023 ES1 protein homolog, mitochondrial 0.107773
MYH14 myosin, heavy chain 14, non-muscle 0.071107
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0692576
PTMA prothymosin, alpha 0.0670226
FTH1 ferritin, heavy polypeptide 1 0.0648768
PKM pyruvate kinase, muscle 0.0618316
LDHA lactate dehydrogenase A 0.0569494
KRT18 keratin 18, type I 0.0569088
KRT19 keratin 19, type I 0.0561714
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0542442
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0539799
B2M beta-2-microglobulin 0.0465587
VEGFA vascular endothelial growth factor A 0.043204
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0414039
EGR1 early growth response 1 0.0400611
PGK1 phosphoglycerate kinase 1 0.0397621
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0368412
LAMA4 laminin, alpha 4 0.0358893
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0344619
ENO1 enolase 1, (alpha) 0.0343612
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0330901
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0329767
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0328425
DNM2 dynamin 2 0.0322361
POTEF POTE ankyrin domain family, member F 0.0317076
MKI67 marker of proliferation Ki-67 0.0305158
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0304985
SRRM2 serine/arginine repetitive matrix 2 0.0302127
CA12 carbonic anhydrase XII 0.0300621
PDIA3 protein disulfide isomerase family A, member 3 0.0298754
HLA-A major histocompatibility complex, class I, A 0.0298538
EEF2 eukaryotic translation elongation factor 2 0.0291335
WASF2 WAS protein family, member 2 0.0290177
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0283109
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0280477
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0280455
RPL3 ribosomal protein L3 0.0279461
AHNAK AHNAK nucleoprotein 0.0279093
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.0278874
NCOR2 nuclear receptor corepressor 2 0.0268284
RPS12 ribosomal protein S12 0.0267068
ZMYND8 zinc finger, MYND-type containing 8 0.0252239
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0235803
KLK10 kallikrein-related peptidase 10 0.0235727
TJP2 tight junction protein 2 0.0230164
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0229689
SET SET nuclear proto-oncogene 0.0228572
TPI1 triosephosphate isomerase 1 0.0226624
SEPTIN9 septin 9 0.0223765
TUBB4B tubulin, beta 4B class IVb 0.0223573
CD44 CD44 molecule (Indian blood group) 0.0220209
TOP2A topoisomerase (DNA) II alpha 170kDa 0.021941
SULF2 sulfatase 2 0.0216758
CLDN4 claudin 4 0.0216386
ACACA acetyl-CoA carboxylase alpha 0.0216204
GMDS GDP-mannose 4,6-dehydratase 0.021357
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0211152
ZFP36 ZFP36 ring finger protein 0.020982
ITGA6 integrin, alpha 6 0.0207206
FAT1 FAT atypical cadherin 1 0.0206139
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0205666
BAIAP2L1 BAI1-associated protein 2-like 1 0.0204092
ENO2 enolase 2 (gamma, neuronal) 0.0203717
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.0199435
EEF1G eukaryotic translation elongation factor 1 gamma 0.0198791
CENPF centromere protein F, 350/400kDa 0.0198483
FAM13A family with sequence similarity 13, member A 0.0195649
TPM3 tropomyosin 3 0.0194811
DSPP dentin sialophosphoprotein 0.0193654
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0193039
CD63 CD63 molecule 0.0188698
VIM vimentin 0.0188679
HDGF hepatoma-derived growth factor 0.0188044
S100P S100 calcium binding protein P 0.0187424
KLF10 Kruppel-like factor 10 0.0186948
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0185713
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0184899
TSPAN3 tetraspanin 3 0.0183912
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0183289
AGRN agrin 0.0182884
ZFP36L1 ZFP36 ring finger protein-like 1 0.0182
CUX1 cut-like homeobox 1 0.0181685
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0179978
ANXA11 annexin A11 0.0179536
MYO18A myosin XVIIIA 0.0178217
CA9 carbonic anhydrase IX 0.0176733
DIAPH2 diaphanous-related formin 2 0.0175948
RPS8 ribosomal protein S8 0.0175192
TMC5 transmembrane channel-like 5 0.0171964
RAI14 retinoic acid induced 14 0.0170477
PDIA6 protein disulfide isomerase family A, member 6 0.0170418
PAQR5 progestin and adipoQ receptor family member V 0.0170094
CLMB calcimembrin 0.0169427
ZMIZ1 zinc finger, MIZ-type containing 1 0.0167671
MUC13 mucin 13, cell surface associated 0.016763
AKAP12 A kinase (PRKA) anchor protein 12 0.016731
MSN moesin 0.0166145
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0165105

decreased expression

Symbol Name Standardized Value
EXT1 exostosin glycosyltransferase 1 -0.121421
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.115315
TXNRD1 thioredoxin reductase 1 -0.107802
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0924465
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0889872
RPLP1 ribosomal protein, large, P1 -0.0883666
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0680663
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0663922
LMO7 LIM domain 7 -0.0615842
EZR ezrin -0.059856
TPT1 tumor protein, translationally-controlled 1 -0.0597499
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0589715
GARS1 glycyl-tRNA synthetase 1 -0.0579046
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.055442
RPS24 ribosomal protein S24 -0.0541175
VCL vinculin -0.0501268
RBM39 RNA binding motif protein 39 -0.0487623
RPLP2 ribosomal protein, large, P2 -0.0486109
RPS19 ribosomal protein S19 -0.0461435
RPS16 ribosomal protein S16 -0.0459871
ACTN4 actinin, alpha 4 -0.045433
PDIA4 protein disulfide isomerase family A, member 4 -0.0452525
RPS21 ribosomal protein S21 -0.0432098
TJP1 tight junction protein 1 -0.0425817
ATXN1 ataxin 1 -0.0425664
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0418923
NAMPT nicotinamide phosphoribosyltransferase -0.0395916
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0382947
KDM3A lysine (K)-specific demethylase 3A -0.0382491
RAD21 RAD21 homolog (S. pombe) -0.0381146
DSCAM Down syndrome cell adhesion molecule -0.0370187
RPS11 ribosomal protein S11 -0.0366963
TUFT1 tuftelin 1 -0.0347157
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0344629
RPL12 ribosomal protein L12 -0.0344468
TMEM65 transmembrane protein 65 -0.0344069
PTK2 protein tyrosine kinase 2 -0.0341873
ANKRD12 ankyrin repeat domain 12 -0.0340406
MBNL2 muscleblind-like splicing regulator 2 -0.033375
EXPH5 exophilin 5 -0.0332961
KLF6 Kruppel-like factor 6 -0.0332767
RPL32 ribosomal protein L32 -0.0330155
JMJD1C jumonji domain containing 1C -0.0325104
IFRD1 interferon-related developmental regulator 1 -0.0325003
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0324674
MYO1E myosin IE -0.0324347
OGA O-GlcNAcase -0.0321601
FBXO32 F-box protein 32 -0.0310627
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0310455
RTN3 reticulon 3 -0.0310159
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0308136
RB1CC1 RB1-inducible coiled-coil 1 -0.029947
TES testin LIM domain protein -0.0295128
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0292577
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0288614
ARHGAP32 Rho GTPase activating protein 32 -0.0286418
GCLC glutamate-cysteine ligase, catalytic subunit -0.0285175
MYL12B myosin, light chain 12B, regulatory -0.0284868
NAP1L1 nucleosome assembly protein 1-like 1 -0.0284166
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0280346
RPL28 ribosomal protein L28 -0.0273219
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0272594
RPL34 ribosomal protein L34 -0.0272515
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0266789
TOP1 topoisomerase (DNA) I -0.0265833
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0263471
SBF2 SET binding factor 2 -0.0260555
ATF3 activating transcription factor 3 -0.0257348
TSC22D2 TSC22 domain family, member 2 -0.0255644
PDZD8 PDZ domain containing 8 -0.0254447
MBNL1 muscleblind-like splicing regulator 1 -0.0254346
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0253544
RPLP0 ribosomal protein, large, P0 -0.0253368
PRKN parkin RBR E3 ubiquitin protein ligase -0.0249869
CEMIP2 cell migration inducing hyaluronidase 2 -0.0249301
RPS5 ribosomal protein S5 -0.0248095
ZBTB20 zinc finger and BTB domain containing 20 -0.0242667
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0240636
RPL18 ribosomal protein L18 -0.0238732
BTBD9 BTB (POZ) domain containing 9 -0.0238465
ZMYM2 zinc finger, MYM-type 2 -0.0235616
SQSTM1 sequestosome 1 -0.0234012
NEK7 NIMA-related kinase 7 -0.0232838
MBD5 methyl-CpG binding domain protein 5 -0.0229634
CANX calnexin -0.0229211
RPL5 ribosomal protein L5 -0.0228342
FOXO3 forkhead box O3 -0.0227605
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0223214
PREPL prolyl endopeptidase-like -0.0222474
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0218539
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0218462
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0217495
UBL3 ubiquitin-like 3 -0.0217459
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0216943
HDLBP high density lipoprotein binding protein -0.0214582
SMYD3 SET and MYND domain containing 3 -0.0213095
ZFAND3 zinc finger, AN1-type domain 3 -0.0212511
SAMD4A sterile alpha motif domain containing 4A -0.0212434
CCNI cyclin I -0.0211418
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0209084