| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.160535 |
| RPL11 | ribosomal protein L11 | 0.160303 |
| RPS12 | ribosomal protein S12 | 0.141228 |
| RPL23 | ribosomal protein L23 | 0.139507 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.127673 |
| DSPP | dentin sialophosphoprotein | 0.120278 |
| RPL37A | ribosomal protein L37a | 0.108937 |
| RACK1 | receptor for activated C kinase 1 | 0.108813 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.104978 |
| ENO1 | enolase 1, (alpha) | 0.10485 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.103323 |
| RPL3 | ribosomal protein L3 | 0.0987298 |
| AHSG | alpha-2-HS-glycoprotein | 0.0930669 |
| NDRG1 | N-myc downstream regulated 1 | 0.0923091 |
| RPL26 | ribosomal protein L26 | 0.0910138 |
| TMSB10 | thymosin beta 10 | 0.0901392 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0846405 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.084146 |
| RPS3 | ribosomal protein S3 | 0.0833685 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0827338 |
| RPS17 | ribosomal protein S17 | 0.075183 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0728399 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.072587 |
| KLF6 | Kruppel-like factor 6 | 0.071927 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0707274 |
| AFDN | afadin, adherens junction formation factor | 0.0677102 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0664038 |
| RNASET2 | ribonuclease T2 | 0.0661748 |
| SVIL | supervillin | 0.0657387 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0652062 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0649094 |
| RPL12 | ribosomal protein L12 | 0.0636014 |
| TF | transferrin | 0.0593391 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.058968 |
| MT2A | metallothionein 2A | 0.0558017 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0528751 |
| CRY1 | cryptochrome circadian clock 1 | 0.0528177 |
| EHBP1 | EH domain binding protein 1 | 0.0516433 |
| RPS19 | ribosomal protein S19 | 0.0516232 |
| PEG3 | paternally expressed 3 | 0.0515581 |
| TNS1 | tensin 1 | 0.0515019 |
| RPS8 | ribosomal protein S8 | 0.0508012 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0496234 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.049071 |
| RPS14 | ribosomal protein S14 | 0.0485085 |
| RPL37 | ribosomal protein L37 | 0.0484808 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0462148 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0449434 |
| RPL4 | ribosomal protein L4 | 0.0442747 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0440787 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0438301 |
| RPL31 | ribosomal protein L31 | 0.043256 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0426856 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0419678 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.041697 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0415204 |
| HMGA1 | high mobility group AT-hook 1 | 0.0414668 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0413341 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0410419 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0408681 |
| FLNB | filamin B, beta | 0.0393622 |
| RPL9 | ribosomal protein L9 | 0.0388462 |
| RPS27A | ribosomal protein S27a | 0.0388288 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0384194 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0377618 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0375152 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0373753 |
| RPL27 | ribosomal protein L27 | 0.0371295 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0371181 |
| FAM107B | family with sequence similarity 107, member B | 0.03668 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0364327 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0364055 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0361667 |
| RPL7 | ribosomal protein L7 | 0.0355472 |
| RPL30 | ribosomal protein L30 | 0.0351987 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0350442 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347561 |
| FMNL2 | formin-like 2 | 0.0331082 |
| SERINC1 | serine incorporator 1 | 0.0321855 |
| WWC2 | WW and C2 domain containing 2 | 0.0320152 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0318886 |
| AHR | aryl hydrocarbon receptor | 0.0318313 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0317842 |
| LYZ | lysozyme | 0.0317211 |
| S100P | S100 calcium binding protein P | 0.0315615 |
| CFB | complement factor B | 0.0311662 |
| TCIM | transcriptional and immune response regulator | 0.0310994 |
| DUSP6 | dual specificity phosphatase 6 | 0.0310826 |
| GK | glycerol kinase | 0.0310761 |
| SON | SON DNA binding protein | 0.030816 |
| RPS15A | ribosomal protein S15a | 0.0307872 |
| RPL18 | ribosomal protein L18 | 0.0307526 |
| FAT1 | FAT atypical cadherin 1 | 0.0302488 |
| B2M | beta-2-microglobulin | 0.0302159 |
| KIF21A | kinesin family member 21A | 0.0302131 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300994 |
| TMEM181 | transmembrane protein 181 | 0.0300614 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0294413 |
| STC2 | stanniocalcin 2 | 0.029188 |
| SMAD3 | SMAD family member 3 | 0.0291109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.271776 |
| IGF2 | insulin-like growth factor 2 | -0.22343 |
| APOA2 | apolipoprotein A-II | -0.14662 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125328 |
| C3 | complement component 3 | -0.10501 |
| GPC6 | glypican 6 | -0.0783068 |
| APOB | apolipoprotein B | -0.0739137 |
| VCL | vinculin | -0.0494357 |
| RTN4 | reticulon 4 | -0.0475541 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0436179 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0398109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0369786 |
| POTEF | POTE ankyrin domain family, member F | -0.0363097 |
| ITGAV | integrin, alpha V | -0.0345048 |
| RPS21 | ribosomal protein S21 | -0.0328807 |
| ACTG1 | actin gamma 1 | -0.0328235 |
| TMEM123 | transmembrane protein 123 | -0.032382 |
| BCL2L1 | BCL2-like 1 | -0.0322323 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0321286 |
| KIAA1217 | KIAA1217 | -0.0312654 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030268 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0299059 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0292983 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0283023 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0282116 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0278703 |
| GPC3 | glypican 3 | -0.0275493 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0270664 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0270587 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0267829 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0266705 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0261364 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0258205 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0255766 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0250624 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0247117 |
| RPL38 | ribosomal protein L38 | -0.0244531 |
| MRTFA | myocardin related transcription factor A | -0.0240804 |
| RPS6 | ribosomal protein S6 | -0.0239899 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0231989 |
| NHSL1 | NHS-like 1 | -0.0227494 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0224833 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0222341 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0218529 |
| PHIP | pleckstrin homology domain interacting protein | -0.0216555 |
| TAOK1 | TAO kinase 1 | -0.0216197 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0215328 |
| PERP | PERP, TP53 apoptosis effector | -0.0213697 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.021269 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0208856 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0207067 |
| PTCHD4 | patched domain containing 4 | -0.0206883 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0205902 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204707 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0200366 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0198977 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0198766 |
| MT1X | metallothionein 1X | -0.0196268 |
| CST3 | cystatin C | -0.0194267 |
| TRIM26 | tripartite motif containing 26 | -0.0193621 |
| ITGA1 | integrin, alpha 1 | -0.0193363 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0193012 |
| GRB2 | growth factor receptor-bound protein 2 | -0.019112 |
| SDC4 | syndecan 4 | -0.01882 |
| MT1E | metallothionein 1E | -0.0187895 |
| PCNX4 | pecanex 4 | -0.0182576 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0182352 |
| S100A10 | S100 calcium binding protein A10 | -0.0180979 |
| FKTN | fukutin | -0.0180528 |
| VDAC1 | voltage-dependent anion channel 1 | -0.018028 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.018015 |
| AOPEP | aminopeptidase O (putative) | -0.0179926 |
| RPS15 | ribosomal protein S15 | -0.017896 |
| RPS16 | ribosomal protein S16 | -0.0178547 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0175529 |
| PCBP2 | poly(rC) binding protein 2 | -0.0174578 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0173877 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.0172863 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0172848 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0171691 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0170207 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0169779 |
| FHIT | fragile histidine triad | -0.0169179 |
| GPHN | gephyrin | -0.0166813 |
| TPM4 | tropomyosin 4 | -0.0164662 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0164311 |
| TMEM87A | transmembrane protein 87A | -0.0164065 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0163973 |
| MED13 | mediator complex subunit 13 | -0.0162125 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0161648 |
| SUMF1 | sulfatase modifying factor 1 | -0.0161102 |
| CANX | calnexin | -0.0160788 |
| PARD3 | par-3 family cell polarity regulator | -0.0160352 |
| ANXA5 | annexin A5 | -0.0160117 |
| CCNL1 | cyclin L1 | -0.0159812 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0159695 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0159514 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.015874 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.015869 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0158667 |
