| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.323807 |
| NDRG1 | N-myc downstream regulated 1 | 0.21398 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.175683 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.162182 |
| MT1X | metallothionein 1X | 0.10722 |
| TMSB10 | thymosin beta 10 | 0.0864059 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0853637 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0792241 |
| RPL23 | ribosomal protein L23 | 0.0744033 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0719055 |
| FLNB | filamin B, beta | 0.0685451 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0665632 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0657918 |
| GLIS3 | GLIS family zinc finger 3 | 0.0630377 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0621935 |
| FN1 | fibronectin 1 | 0.0594148 |
| ANXA1 | annexin A1 | 0.0581005 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0554889 |
| TPI1 | triosephosphate isomerase 1 | 0.0532937 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.048676 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0482015 |
| ZNF841 | zinc finger protein 841 | 0.0479238 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0469015 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0429844 |
| LOX | lysyl oxidase | 0.0427166 |
| NAV2 | neuron navigator 2 | 0.0425809 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0423047 |
| TRAM2 | translocation associated membrane protein 2 | 0.0420333 |
| RPL26 | ribosomal protein L26 | 0.0413976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0406322 |
| RPS3 | ribosomal protein S3 | 0.0400657 |
| MMP12 | matrix metallopeptidase 12 | 0.0383919 |
| RPL3 | ribosomal protein L3 | 0.03688 |
| DTNA | dystrobrevin, alpha | 0.0368417 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.036771 |
| PGK1 | phosphoglycerate kinase 1 | 0.036433 |
| AHNAK | AHNAK nucleoprotein | 0.0362995 |
| RPL21 | ribosomal protein L21 | 0.0356726 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0352529 |
| RPL12 | ribosomal protein L12 | 0.0352505 |
| ARRDC3 | arrestin domain containing 3 | 0.034831 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0336157 |
| EGFR | epidermal growth factor receptor | 0.0335666 |
| RACK1 | receptor for activated C kinase 1 | 0.0333855 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0333018 |
| PDS5B | PDS5 cohesin associated factor B | 0.0332989 |
| RPL11 | ribosomal protein L11 | 0.0330838 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0328667 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0326769 |
| FMNL2 | formin-like 2 | 0.0326114 |
| CBX3 | chromobox homolog 3 | 0.0319197 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0313539 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0312298 |
| DST | dystonin | 0.0309678 |
| B2M | beta-2-microglobulin | 0.0305732 |
| LOC112694756 | uncharaterized LOC112694756 | 0.030113 |
| RPS17 | ribosomal protein S17 | 0.0295795 |
| ADM | adrenomedullin | 0.0294854 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290721 |
| HELZ | helicase with zinc finger | 0.0279193 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0279163 |
| PLIN2 | perilipin 2 | 0.0277139 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.027438 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0273628 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.026637 |
| YBX1 | Y box binding protein 1 | 0.0265793 |
| FAM162A | family with sequence similarity 162, member A | 0.0264657 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0259349 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0259085 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0257494 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0255508 |
| PLCB4 | phospholipase C, beta 4 | 0.0255036 |
| YBX3 | Y box binding protein 3 | 0.025428 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0252941 |
| RPL36 | ribosomal protein L36 | 0.024776 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0245694 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0244938 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0243283 |
| BSG | basigin (Ok blood group) | 0.023893 |
| JUN | jun proto-oncogene | 0.0237683 |
| FLNA | filamin A, alpha | 0.0233414 |
| AFAP1 | actin filament associated protein 1 | 0.023292 |
| FOXN3 | forkhead box N3 | 0.0231437 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0231254 |
| TPD52 | tumor protein D52 | 0.0230049 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0229205 |
| RPL30 | ribosomal protein L30 | 0.0228275 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0227214 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0226805 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0226241 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0226126 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | 0.0224382 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0223703 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0222985 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0222883 |
| FAM107B | family with sequence similarity 107, member B | 0.0221135 |
| ANO6 | anoctamin 6 | 0.0220781 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0220184 |
| RPL18 | ribosomal protein L18 | 0.0220151 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0219638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.166357 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118886 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112293 |
| CD44 | CD44 molecule (Indian blood group) | -0.0964267 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0832758 |
| ACTG1 | actin gamma 1 | -0.0821109 |
| CANX | calnexin | -0.0751985 |
| TPM1 | tropomyosin 1 (alpha) | -0.0740358 |
| VCL | vinculin | -0.0704634 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0626272 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0620219 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0586429 |
| TPM4 | tropomyosin 4 | -0.0585077 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0583827 |
| SQSTM1 | sequestosome 1 | -0.0577373 |
| CAVIN1 | caveolae associated protein 1 | -0.0555499 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0554432 |
| DEK | DEK proto-oncogene | -0.0553222 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0543917 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0496756 |
| RPLP2 | ribosomal protein, large, P2 | -0.0495104 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0481076 |
| RPL35A | ribosomal protein L35a | -0.0478681 |
| TXNRD1 | thioredoxin reductase 1 | -0.0451429 |
| POTEF | POTE ankyrin domain family, member F | -0.0435449 |
| HMGB1 | high mobility group box 1 | -0.0432348 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0405245 |
| TENM3 | teneurin transmembrane protein 3 | -0.0404559 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0385525 |
| DIAPH3 | diaphanous-related formin 3 | -0.0380526 |
| PLSCR1 | phospholipid scramblase 1 | -0.035361 |
| GOLGA4 | golgin A4 | -0.0349954 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0344788 |
| RPS6 | ribosomal protein S6 | -0.0343564 |
| RTN4 | reticulon 4 | -0.0342874 |
| CALR | calreticulin | -0.0340475 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336065 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0329098 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0328844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0327073 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0325244 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0323956 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0319 |
| IL6ST | interleukin 6 signal transducer | -0.0313702 |
| RIGI | RNA sensor RIG-I | -0.0310736 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0310626 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309295 |
| HLA-E | major histocompatibility complex, class I, E | -0.0308309 |
| IER3 | immediate early response 3 | -0.0302758 |
| RPL7A | ribosomal protein L7a | -0.0295556 |
| RPL38 | ribosomal protein L38 | -0.0293148 |
| WWOX | WW domain containing oxidoreductase | -0.0293075 |
| RPS25 | ribosomal protein S25 | -0.0292863 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0292586 |
| KRT8 | keratin 8, type II | -0.029183 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0289711 |
| SET | SET nuclear proto-oncogene | -0.028818 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0286687 |
| ANXA5 | annexin A5 | -0.0286375 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0286148 |
| FUS | FUS RNA binding protein | -0.0286106 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0283422 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0282476 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0280628 |
| JMJD1C | jumonji domain containing 1C | -0.0280117 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0275287 |
| OSMR | oncostatin M receptor | -0.0275216 |
| USP1 | ubiquitin specific peptidase 1 | -0.0274242 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270821 |
| PKM | pyruvate kinase, muscle | -0.0270367 |
| CCND1 | cyclin D1 | -0.0269976 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0268157 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0266825 |
| CLIC4 | chloride intracellular channel 4 | -0.0266785 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.026436 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0261572 |
| TMEM41B | transmembrane protein 41B | -0.0261275 |
| S100A10 | S100 calcium binding protein A10 | -0.025987 |
| VIM | vimentin | -0.0257948 |
| RTN3 | reticulon 3 | -0.0253607 |
| RHOA | ras homolog family member A | -0.0252639 |
| LUZP1 | leucine zipper protein 1 | -0.0251742 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0250838 |
| RAN | RAN, member RAS oncogene family | -0.025041 |
| LIMA1 | LIM domain and actin binding 1 | -0.0247487 |
| NEK7 | NIMA-related kinase 7 | -0.0246159 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0245135 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0245102 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0240823 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0239119 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0238794 |
| CENPF | centromere protein F, 350/400kDa | -0.0238507 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0237417 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0236915 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0236241 |
| TUBA1B | tubulin, alpha 1b | -0.0236012 |
| NKTR | natural killer cell triggering receptor | -0.0235556 |
| CLSPN | claspin | -0.0232715 |
| ITGAV | integrin, alpha V | -0.0232419 |
