Diammonium Glycyrrhizinate_LOX-IMVI Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Diammonium Glycyrrhizinate perturbation in LOX-IMVI cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Diammonium Glycyrrhizinate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
RPL23 ribosomal protein L23 0.162639
DTNA dystrobrevin, alpha 0.152484
RPS3 ribosomal protein S3 0.117841
RPS12 ribosomal protein S12 0.114029
TMSB10 thymosin beta 10 0.10896
EFNA5 ephrin-A5 0.0925608
RPS6 ribosomal protein S6 0.0922322
FTL ferritin, light polypeptide 0.0890051
RPL37A ribosomal protein L37a 0.0867787
EEF2 eukaryotic translation elongation factor 2 0.0827454
RACK1 receptor for activated C kinase 1 0.0815514
MT2A metallothionein 2A 0.078629
RPS17 ribosomal protein S17 0.0766564
RPL12 ribosomal protein L12 0.0677961
RPS19 ribosomal protein S19 0.0667715
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0620388
RPS8 ribosomal protein S8 0.0558744
RPL3 ribosomal protein L3 0.0554644
RPL11 ribosomal protein L11 0.0552939
RPL9 ribosomal protein L9 0.0505214
RPL31 ribosomal protein L31 0.050423
NDRG1 N-myc downstream regulated 1 0.0497514
EXT1 exostosin glycosyltransferase 1 0.0489652
RPL21 ribosomal protein L21 0.0485431
RPL26 ribosomal protein L26 0.0480586
RPL7 ribosomal protein L7 0.046144
RPL36 ribosomal protein L36 0.0453411
EGR1 early growth response 1 0.0438856
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0406081
RPS4X ribosomal protein S4, X-linked 0.039988
PRKCE protein kinase C, epsilon 0.038782
RPLP1 ribosomal protein, large, P1 0.0368915
RPL37 ribosomal protein L37 0.0368684
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0365976
RPL18 ribosomal protein L18 0.0341141
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0338847
RPL13A ribosomal protein L13a 0.0334199
FLNA filamin A, alpha 0.0321558
ENO2 enolase 2 (gamma, neuronal) 0.0316162
RPL5 ribosomal protein L5 0.031512
RPL27 ribosomal protein L27 0.0307603
EEF1G eukaryotic translation elongation factor 1 gamma 0.0306006
HMGA1 high mobility group AT-hook 1 0.0301991
HDAC9 histone deacetylase 9 0.0296481
RPS27 ribosomal protein S27 0.029273
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.0288751
RPL35A ribosomal protein L35a 0.028782
RPL30 ribosomal protein L30 0.02796
IRS2 insulin receptor substrate 2 0.0278648
MCL1 myeloid cell leukemia 1 0.0278372
RPS2 ribosomal protein S2 0.0273317
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.027139
ADAM32 ADAM metallopeptidase domain 32 0.0266677
NAP1L1 nucleosome assembly protein 1-like 1 0.0266531
TPM3 tropomyosin 3 0.0263581
UQCRB ubiquinol-cytochrome c reductase binding protein 0.024939
RPL4 ribosomal protein L4 0.0247889
TPI1 triosephosphate isomerase 1 0.0245924
NACA nascent polypeptide-associated complex alpha subunit 0.0245336
MYO10 myosin X 0.0241613
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0237376
PCBP2 poly(rC) binding protein 2 0.0236201
LIMA1 LIM domain and actin binding 1 0.0232693
MARCHF4 membrane associated ring-CH-type finger 4 0.0231102
RPS14 ribosomal protein S14 0.0229867
RPS13 ribosomal protein S13 0.0225273
YBX1 Y box binding protein 1 0.0215668
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.020544
B2M beta-2-microglobulin 0.0202725
LIMCH1 LIM and calponin homology domains 1 0.0198975
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.0195823
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0193742
RPL19 ribosomal protein L19 0.0191736
SRRM2 serine/arginine repetitive matrix 2 0.0188723
MSN moesin 0.0187661
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0187126
PBX3 pre-B-cell leukemia homeobox 3 0.0184996
PKM pyruvate kinase, muscle 0.0184162
RPS27A ribosomal protein S27a 0.0183897
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0182006
ZCCHC7 zinc finger, CCHC domain containing 7 0.0181875
RPS15A ribosomal protein S15a 0.0181296
RPS25 ribosomal protein S25 0.0180925
EIF5B eukaryotic translation initiation factor 5B 0.0178668
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0177463
JUN jun proto-oncogene 0.0175232
CDH13 cadherin 13 0.0173637
SMAP1 small ArfGAP 1 0.0172146
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0170222
CTIF CBP80/20-dependent translation initiation factor 0.0168516
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.016418
SON SON DNA binding protein 0.0164029
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0163785
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0161054
VIM vimentin 0.0159086
PHACTR1 phosphatase and actin regulator 1 0.015901
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0158532
CTBP2 C-terminal binding protein 2 0.0158408
INTS6 integrator complex subunit 6 0.0155788
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.015283

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.247694
MMP12 matrix metallopeptidase 12 -0.119201
VCL vinculin -0.0983203
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0921403
AHNAK AHNAK nucleoprotein -0.0743223
FNDC3B fibronectin type III domain containing 3B -0.070302
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0646525
CD44 CD44 molecule (Indian blood group) -0.0642808
CTSB cathepsin B -0.0583383
RTN4 reticulon 4 -0.0582651
CDK17 cyclin-dependent kinase 17 -0.0560988
ACTG1 actin gamma 1 -0.0547343
FRMD6 FERM domain containing 6 -0.0545484
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0537049
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0531915
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0508613
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0503442
ELL2 elongation factor, RNA polymerase II, 2 -0.0499545
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0493467
GPC6 glypican 6 -0.0491849
NAMPT nicotinamide phosphoribosyltransferase -0.0481329
JMJD1C jumonji domain containing 1C -0.0472896
ALCAM activated leukocyte cell adhesion molecule -0.0472847
ADAM19 ADAM metallopeptidase domain 19 -0.0468794
RAD21 RAD21 homolog (S. pombe) -0.0464745
PTCHD4 patched domain containing 4 -0.0460271
ZFAND3 zinc finger, AN1-type domain 3 -0.0443302
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0440065
FN1 fibronectin 1 -0.0439379
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0429068
TNNC1 troponin C type 1 (slow) -0.042642
DST dystonin -0.0414214
ANXA2 annexin A2 -0.0413037
ENKUR enkurin, TRPC channel interacting protein -0.0404469
PDE4D phosphodiesterase 4D, cAMP-specific -0.0399802
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0395624
RAI14 retinoic acid induced 14 -0.0392598
DPYD dihydropyrimidine dehydrogenase -0.0380969
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -0.037798
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0372355
CAVIN1 caveolae associated protein 1 -0.0371078
KYNU kynureninase -0.0365935
ANKRD28 ankyrin repeat domain 28 -0.0364459
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0363505
MAML2 mastermind-like 2 (Drosophila) -0.0358025
TXNRD1 thioredoxin reductase 1 -0.0357675
SMAD3 SMAD family member 3 -0.0357254
OSMR oncostatin M receptor -0.0356139
RBM39 RNA binding motif protein 39 -0.0347249
UGCG UDP-glucose ceramide glucosyltransferase -0.0345889
BMAL2 basic helix-loop-helix ARNT like 2 -0.034486
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0337251
SBF2 SET binding factor 2 -0.0331944
MED13L mediator complex subunit 13-like -0.0328983
KPNB1 karyopherin (importin) beta 1 -0.032783
ERBIN erbb2 interacting protein -0.0319378
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0317173
KDM3A lysine (K)-specific demethylase 3A -0.0315127
NF1 neurofibromin 1 -0.0313489
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0311817
NRP2 neuropilin 2 -0.0310422
APP amyloid beta (A4) precursor protein -0.0305022
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0298249
TPM4 tropomyosin 4 -0.0296455
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0293173
H1-0 H1.0 linker histone -0.0292987
TMEM123 transmembrane protein 123 -0.029195
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0289369
IFI16 interferon, gamma-inducible protein 16 -0.0286521
BPTF bromodomain PHD finger transcription factor -0.0286434
SPAG9 sperm associated antigen 9 -0.0286308
SASH1 SAM and SH3 domain containing 1 -0.0284474
RLF rearranged L-myc fusion -0.0281259
HAS2 hyaluronan synthase 2 -0.0280746
OGA O-GlcNAcase -0.0279737
CANX calnexin -0.0278811
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0277955
EMP1 epithelial membrane protein 1 -0.0277792
ANO6 anoctamin 6 -0.0274734
NPC1 Niemann-Pick disease, type C1 -0.02744
FOXP1 forkhead box P1 -0.0273018
NTM neurotrimin -0.0271331
MAP1B microtubule-associated protein 1B -0.0271175
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0271144
TAOK1 TAO kinase 1 -0.0270446
ANTXR2 anthrax toxin receptor 2 -0.0270413
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0269162
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.026805
SENP6 SUMO1/sentrin specific peptidase 6 -0.0266646
ETV6 ets variant 6 -0.0262533
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0261754
IL6ST interleukin 6 signal transducer -0.0260886
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0259262
PHF3 PHD finger protein 3 -0.0258216
PTBP3 polypyrimidine tract binding protein 3 -0.0254837
BZW1 basic leucine zipper and W2 domains 1 -0.0249511
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0247832
CD109 CD109 molecule -0.0247182
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0246073
SEPTIN10 septin 10 -0.0245665