| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.167694 |
| MT2A | metallothionein 2A | 0.136573 |
| STC1 | stanniocalcin 1 | 0.0951786 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0945941 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0871981 |
| NDRG1 | N-myc downstream regulated 1 | 0.0751051 |
| B2M | beta-2-microglobulin | 0.0719108 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0661495 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0619071 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0593909 |
| ARRDC3 | arrestin domain containing 3 | 0.0588386 |
| FAM13A | family with sequence similarity 13, member A | 0.0583777 |
| H1-0 | H1.0 linker histone | 0.0547524 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0522072 |
| RPL11 | ribosomal protein L11 | 0.0495826 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0495454 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0480418 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0472393 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.045336 |
| MT1X | metallothionein 1X | 0.0437389 |
| SMAD3 | SMAD family member 3 | 0.043115 |
| RPL23 | ribosomal protein L23 | 0.0414931 |
| TPI1 | triosephosphate isomerase 1 | 0.0403494 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0392661 |
| YBX3 | Y box binding protein 3 | 0.0387435 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0375619 |
| KRT18 | keratin 18, type I | 0.0358104 |
| SON | SON DNA binding protein | 0.0339471 |
| SLTM | SAFB-like, transcription modulator | 0.0339152 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0321776 |
| RPS4X | ribosomal protein S4, X-linked | 0.0311686 |
| RHOV | ras homolog family member V | 0.0302166 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.029243 |
| RPL3 | ribosomal protein L3 | 0.0285209 |
| IRS2 | insulin receptor substrate 2 | 0.0277136 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0275119 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0271901 |
| EFNA5 | ephrin-A5 | 0.0269742 |
| RPL26 | ribosomal protein L26 | 0.0266779 |
| RPS19 | ribosomal protein S19 | 0.0265811 |
| IFI44L | interferon-induced protein 44-like | 0.0264418 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0264397 |
| RPL12 | ribosomal protein L12 | 0.0263437 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0260761 |
| CAV2 | caveolin 2 | 0.0257194 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0256029 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0253756 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0248166 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0246635 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0245026 |
| LDHA | lactate dehydrogenase A | 0.0244408 |
| RNF213 | ring finger protein 213 | 0.0240038 |
| AREG | amphiregulin | 0.0238939 |
| RPS12 | ribosomal protein S12 | 0.0237421 |
| TES | testin LIM domain protein | 0.0232715 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0232001 |
| S100A11 | S100 calcium binding protein A11 | 0.0229685 |
| RPS15A | ribosomal protein S15a | 0.0224348 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0224338 |
| LAMC2 | laminin, gamma 2 | 0.0222634 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0222493 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0216517 |
| PGK1 | phosphoglycerate kinase 1 | 0.0214732 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0213868 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.021319 |
| EGR1 | early growth response 1 | 0.0211071 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0208575 |
| TJP1 | tight junction protein 1 | 0.0206001 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0205708 |
| HBP1 | HMG-box transcription factor 1 | 0.020537 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0204228 |
| RPL18 | ribosomal protein L18 | 0.0203572 |
| RACK1 | receptor for activated C kinase 1 | 0.0202961 |
| RPL30 | ribosomal protein L30 | 0.0200225 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0198398 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0189682 |
| RNF145 | ring finger protein 145 | 0.0188066 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0185592 |
| DHFR | dihydrofolate reductase | 0.0184682 |
| CST3 | cystatin C | 0.0184016 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0182997 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0180565 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0179683 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0177063 |
| ASPH | aspartate beta-hydroxylase | 0.0176589 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0175926 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0175887 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0174951 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0173774 |
| MIDN | midnolin | 0.0171089 |
| MYO1B | myosin IB | 0.0170397 |
| PHF21A | PHD finger protein 21A | 0.016924 |
| MKI67 | marker of proliferation Ki-67 | 0.0168762 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0164181 |
| GPX4 | glutathione peroxidase 4 | 0.016373 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0162926 |
| KIAA0040 | KIAA0040 | 0.016269 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0161167 |
| RPL21 | ribosomal protein L21 | 0.0160643 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.016048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261424 |
| EGFR | epidermal growth factor receptor | -0.242863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.214101 |
| GRAMD1B | GRAM domain containing 1B | -0.0995376 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0844714 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0808519 |
| PTMA | prothymosin, alpha | -0.0778571 |
| RPS25 | ribosomal protein S25 | -0.0681279 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.067865 |
| INTS6 | integrator complex subunit 6 | -0.0666934 |
| CANX | calnexin | -0.0660754 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0657624 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0647573 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0617346 |
| MCL1 | myeloid cell leukemia 1 | -0.0576152 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0575311 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0571368 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.055335 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.054826 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0544587 |
| LAMA4 | laminin, alpha 4 | -0.0533218 |
| ACTG1 | actin gamma 1 | -0.0530583 |
| VCL | vinculin | -0.0529 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0528183 |
| UBC | ubiquitin C | -0.0507761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.049455 |
| TXNRD1 | thioredoxin reductase 1 | -0.0492283 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0481676 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0476847 |
| FBXO11 | F-box protein 11 | -0.0471081 |
| TMEM165 | transmembrane protein 165 | -0.0465093 |
| S100A10 | S100 calcium binding protein A10 | -0.0455262 |
| HYOU1 | hypoxia up-regulated 1 | -0.0452768 |
| ENO1 | enolase 1, (alpha) | -0.0437466 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0437017 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0436937 |
| AGR2 | anterior gradient 2 | -0.0434207 |
| GOLGA4 | golgin A4 | -0.0432011 |
| RAB10 | RAB10, member RAS oncogene family | -0.0430999 |
| MYOF | myoferlin | -0.0422453 |
| WASF2 | WAS protein family, member 2 | -0.0416417 |
| RPS6 | ribosomal protein S6 | -0.041168 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0410044 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0409226 |
| CALR | calreticulin | -0.0408536 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0406879 |
| RPS8 | ribosomal protein S8 | -0.040483 |
| HM13 | histocompatibility (minor) 13 | -0.0403032 |
| USP34 | ubiquitin specific peptidase 34 | -0.0401198 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0401073 |
| PKM | pyruvate kinase, muscle | -0.0400877 |
| CUX1 | cut-like homeobox 1 | -0.0392345 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0389336 |
| HDLBP | high density lipoprotein binding protein | -0.0382926 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0377982 |
| MAGEA4 | melanoma antigen family A4 | -0.0377868 |
| VMP1 | vacuole membrane protein 1 | -0.0371564 |
| RPL35A | ribosomal protein L35a | -0.0370318 |
| RPS23 | ribosomal protein S23 | -0.0363894 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0357016 |
| RPS29 | ribosomal protein S29 | -0.0354393 |
| RPS27A | ribosomal protein S27a | -0.035106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348375 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.0347602 |
| MAGT1 | magnesium transporter 1 | -0.0344385 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0343533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0341975 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0340902 |
| GOLGB1 | golgin B1 | -0.0336213 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0334564 |
| SRP54 | signal recognition particle 54kDa | -0.0332965 |
| SEC24D | SEC24 family member D | -0.0332806 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0332784 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0327557 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0316469 |
| ANXA2 | annexin A2 | -0.0310198 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308738 |
| FUS | FUS RNA binding protein | -0.030709 |
| MTDH | metadherin | -0.0300099 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0299822 |
| JMJD1C | jumonji domain containing 1C | -0.0298496 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0298495 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0297645 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0296579 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0292732 |
| ENSA | endosulfine alpha | -0.029225 |
| NTN4 | netrin 4 | -0.0291245 |
| MAP7 | microtubule-associated protein 7 | -0.0289489 |
| CPE | carboxypeptidase E | -0.0288519 |
| FAM193A | family with sequence similarity 193, member A | -0.0288206 |
| COG5 | component of oligomeric golgi complex 5 | -0.0287846 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0283544 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0282972 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0276213 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0275866 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0275474 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0274536 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0272982 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0271649 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0271446 |
