| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Diammonium Glycyrrhizinate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.244311 |
| TMSB10 | thymosin beta 10 | 0.128851 |
| RPL23 | ribosomal protein L23 | 0.0982523 |
| RPL3 | ribosomal protein L3 | 0.0748126 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0740833 |
| FTL | ferritin, light polypeptide | 0.0702214 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0609892 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0499291 |
| STC1 | stanniocalcin 1 | 0.0461602 |
| RPS12 | ribosomal protein S12 | 0.0420955 |
| RPS19 | ribosomal protein S19 | 0.0411464 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0403406 |
| RPL11 | ribosomal protein L11 | 0.0398625 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0377854 |
| RPS27 | ribosomal protein S27 | 0.0373978 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0368597 |
| RACK1 | receptor for activated C kinase 1 | 0.0360568 |
| RPL4 | ribosomal protein L4 | 0.0360118 |
| RPL36 | ribosomal protein L36 | 0.035829 |
| RPS17 | ribosomal protein S17 | 0.035799 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0346306 |
| TPI1 | triosephosphate isomerase 1 | 0.0316415 |
| NDRG1 | N-myc downstream regulated 1 | 0.0312494 |
| HLA-A | major histocompatibility complex, class I, A | 0.0308294 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0300028 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0299255 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.027822 |
| RPL18 | ribosomal protein L18 | 0.0274358 |
| KYNU | kynureninase | 0.0273537 |
| PLEC | plectin | 0.0262357 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0261566 |
| RPS3 | ribosomal protein S3 | 0.0257327 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0247618 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0239532 |
| FLNA | filamin A, alpha | 0.0237583 |
| CTBP2 | C-terminal binding protein 2 | 0.0236101 |
| RPS4X | ribosomal protein S4, X-linked | 0.0234135 |
| RPL37 | ribosomal protein L37 | 0.0231853 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231605 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0229682 |
| HLA-C | major histocompatibility complex, class I, C | 0.0224191 |
| RPL13A | ribosomal protein L13a | 0.0222676 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0222073 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0218495 |
| RPL7 | ribosomal protein L7 | 0.0218324 |
| RPL37A | ribosomal protein L37a | 0.02162 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.021544 |
| SFTPA2 | surfactant protein A2 | 0.0214547 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0210556 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0210362 |
| RPL27 | ribosomal protein L27 | 0.0208308 |
| EGR1 | early growth response 1 | 0.0207722 |
| RPL30 | ribosomal protein L30 | 0.0207394 |
| RPL26 | ribosomal protein L26 | 0.0206247 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0206058 |
| RPS14 | ribosomal protein S14 | 0.0203197 |
| ANGPTL4 | angiopoietin-like 4 | 0.0201382 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0196027 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0190741 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0189162 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187569 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0187367 |
| SERF2 | small EDRK-rich factor 2 | 0.0183961 |
| SMAD2 | SMAD family member 2 | 0.0182309 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0181823 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0176711 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0176429 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0176324 |
| LAMA5 | laminin, alpha 5 | 0.0171594 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0171556 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0171375 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0169418 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0169221 |
| PYGL | phosphorylase, glycogen, liver | 0.0168326 |
| RPL35A | ribosomal protein L35a | 0.0167634 |
| BRD2 | bromodomain containing 2 | 0.0165607 |
| FLNB | filamin B, beta | 0.0164669 |
| RPS8 | ribosomal protein S8 | 0.0164333 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0161792 |
| SERINC1 | serine incorporator 1 | 0.0160396 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0160107 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0155446 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0155143 |
| FOXO3 | forkhead box O3 | 0.0153496 |
| CASC3 | cancer susceptibility candidate 3 | 0.015293 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0150861 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0150466 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0150451 |
| GPX4 | glutathione peroxidase 4 | 0.0147951 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0142912 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0142654 |
| DCTN1 | dynactin 1 | 0.01425 |
| PFDN2 | prefoldin subunit 2 | 0.014157 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0141413 |
| CREBBP | CREB binding protein | 0.0140072 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0139661 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0139257 |
| HMOX1 | heme oxygenase 1 | 0.0138503 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0133971 |
| RPL21 | ribosomal protein L21 | 0.0133667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.209095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.150367 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.104186 |
| GRAMD1B | GRAM domain containing 1B | -0.103017 |
| TXNRD1 | thioredoxin reductase 1 | -0.101155 |
| RPS27A | ribosomal protein S27a | -0.0994621 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0897507 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0870916 |
| ACTG1 | actin gamma 1 | -0.0853851 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0804414 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0799542 |
| ENO1 | enolase 1, (alpha) | -0.0799171 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0787601 |
| PTMA | prothymosin, alpha | -0.0767579 |
| POTEF | POTE ankyrin domain family, member F | -0.0762685 |
| IGF2 | insulin-like growth factor 2 | -0.0698435 |
| UBC | ubiquitin C | -0.0693878 |
| ASPH | aspartate beta-hydroxylase | -0.0671917 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0663973 |
| FGB | fibrinogen beta chain | -0.0587619 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0566456 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0554592 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0554192 |
| TPM4 | tropomyosin 4 | -0.0540836 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0529467 |
| IER3 | immediate early response 3 | -0.0520347 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0517355 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0508589 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0483044 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0469948 |
| S100A6 | S100 calcium binding protein A6 | -0.046616 |
| WWOX | WW domain containing oxidoreductase | -0.0454387 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.04507 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0449118 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0446023 |
| ZNF207 | zinc finger protein 207 | -0.0436466 |
| PKM | pyruvate kinase, muscle | -0.0435728 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0433308 |
| RTN4 | reticulon 4 | -0.042886 |
| CENPF | centromere protein F, 350/400kDa | -0.0416421 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0412827 |
| NOP58 | NOP58 ribonucleoprotein | -0.0412437 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0401462 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0389964 |
| DEK | DEK proto-oncogene | -0.0389429 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0376586 |
| RBM25 | RNA binding motif protein 25 | -0.0373985 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.036947 |
| CANX | calnexin | -0.0367533 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0365261 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0357888 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0357214 |
| HDGF | hepatoma-derived growth factor | -0.034866 |
| SEPTIN7 | septin 7 | -0.0348561 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0344971 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0340203 |
| S100A10 | S100 calcium binding protein A10 | -0.0335834 |
| GLG1 | golgi glycoprotein 1 | -0.0332309 |
| MKI67 | marker of proliferation Ki-67 | -0.0332138 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0331511 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0328942 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0327347 |
| FAM107B | family with sequence similarity 107, member B | -0.032542 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0319261 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0313968 |
| JMJD1C | jumonji domain containing 1C | -0.0309741 |
| TNPO1 | transportin 1 | -0.0309316 |
| TPM3 | tropomyosin 3 | -0.0305332 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0304621 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0303378 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.030336 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0302151 |
| ZNF292 | zinc finger protein 292 | -0.0300814 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0300643 |
| TUBA1B | tubulin, alpha 1b | -0.0294393 |
| ANXA2 | annexin A2 | -0.0293205 |
| XPO1 | exportin 1 | -0.0287985 |
| IL6 | interleukin 6 | -0.0285833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0282272 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0282162 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0276402 |
| MYOF | myoferlin | -0.0275649 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0274493 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0274112 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0272739 |
| NEMF | nuclear export mediator factor | -0.0271025 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270844 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0270809 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0270035 |
| CALR | calreticulin | -0.0269866 |
| LDHA | lactate dehydrogenase A | -0.0269828 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268938 |
| SQSTM1 | sequestosome 1 | -0.0266813 |
| PCBP2 | poly(rC) binding protein 2 | -0.0265155 |
| RAN | RAN, member RAS oncogene family | -0.0263944 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0256026 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0255758 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0254445 |
| LDHB | lactate dehydrogenase B | -0.0254333 |
