| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.105223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0899204 |
| B2M | beta-2-microglobulin | 0.0565237 |
| NDRG1 | N-myc downstream regulated 1 | 0.056484 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0537144 |
| MT2A | metallothionein 2A | 0.0498845 |
| FTL | ferritin, light polypeptide | 0.0478808 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0477627 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.047314 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0461714 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0459567 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0453253 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0442129 |
| ENO1 | enolase 1, (alpha) | 0.0426637 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0401409 |
| RIGI | RNA sensor RIG-I | 0.039741 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0392182 |
| RPS19 | ribosomal protein S19 | 0.0391879 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0383005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0378912 |
| PGK1 | phosphoglycerate kinase 1 | 0.0363525 |
| PCBP2 | poly(rC) binding protein 2 | 0.0361161 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.035884 |
| RPS3 | ribosomal protein S3 | 0.0358176 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0358014 |
| CANX | calnexin | 0.0354435 |
| PTGES2 | prostaglandin E synthase 2 | 0.0352083 |
| TMSB10 | thymosin beta 10 | 0.0338752 |
| KIAA1217 | KIAA1217 | 0.0336386 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0336291 |
| FMNL2 | formin-like 2 | 0.0333042 |
| RPS12 | ribosomal protein S12 | 0.0329152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328725 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0323646 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0322085 |
| LDHA | lactate dehydrogenase A | 0.0320972 |
| CPE | carboxypeptidase E | 0.0318691 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0316423 |
| RBM39 | RNA binding motif protein 39 | 0.0312289 |
| TMSB4X | thymosin beta 4, X-linked | 0.0312189 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0307734 |
| SNX6 | sorting nexin 6 | 0.0304018 |
| CDC27 | cell division cycle 27 | 0.0303552 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.030351 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0300359 |
| LMAN1 | lectin, mannose-binding, 1 | 0.029912 |
| SETD5 | SET domain containing 5 | 0.0296583 |
| RPL11 | ribosomal protein L11 | 0.0296363 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290343 |
| MLEC | malectin | 0.0288632 |
| SEC24D | SEC24 family member D | 0.0280693 |
| COPA | coatomer protein complex, subunit alpha | 0.0280647 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0278867 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.027819 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0274614 |
| IGF2 | insulin-like growth factor 2 | 0.0266556 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0265952 |
| MSI2 | musashi RNA-binding protein 2 | 0.0265369 |
| FOXJ3 | forkhead box J3 | 0.0265113 |
| PHF21A | PHD finger protein 21A | 0.0263979 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0262336 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0262233 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0260634 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0260009 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0259777 |
| ABLIM1 | actin binding LIM protein 1 | 0.0258557 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0257211 |
| PKM | pyruvate kinase, muscle | 0.0256634 |
| CFDP1 | craniofacial development protein 1 | 0.0255887 |
| TMEM41B | transmembrane protein 41B | 0.0255581 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0255576 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0254824 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0253478 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0252884 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250632 |
| LOX | lysyl oxidase | 0.0247716 |
| AUTS2 | autism susceptibility candidate 2 | 0.024718 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0247071 |
| IDS | iduronate 2-sulfatase | 0.0245983 |
| STC1 | stanniocalcin 1 | 0.0244834 |
| SBF2 | SET binding factor 2 | 0.0242482 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0241785 |
| NCKAP1 | NCK-associated protein 1 | 0.0241589 |
| SMAD3 | SMAD family member 3 | 0.0241141 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0238983 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0237258 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0236857 |
| NCOA3 | nuclear receptor coactivator 3 | 0.023664 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0234447 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0233688 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0232871 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.0232522 |
| ERI3 | ERI1 exoribonuclease family member 3 | 0.0231813 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0231556 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0231163 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0230889 |
| BRD2 | bromodomain containing 2 | 0.0229886 |
| TKT | transketolase | 0.0228811 |
| INSIG2 | insulin induced gene 2 | 0.0228677 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0228571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.124667 |
| MYO1E | myosin IE | -0.119868 |
| LMO7 | LIM domain 7 | -0.117937 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.117866 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0957862 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0659091 |
| LAMC2 | laminin, gamma 2 | -0.0580168 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.056342 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0553966 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0553221 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0546185 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0519463 |
| RBM47 | RNA binding motif protein 47 | -0.0518759 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0502286 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.050128 |
| ANXA2 | annexin A2 | -0.0500578 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0500038 |
| SVIL | supervillin | -0.0494792 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.048188 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.047429 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0466156 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0437577 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0428575 |
| ERBIN | erbb2 interacting protein | -0.0418671 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0409955 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0406245 |
| MUC16 | mucin 16, cell surface associated | -0.0400736 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0398897 |
| CDK13 | cyclin-dependent kinase 13 | -0.0395505 |
| POTEF | POTE ankyrin domain family, member F | -0.0373394 |
| CLDN4 | claudin 4 | -0.0370502 |
| FNIP1 | folliculin interacting protein 1 | -0.0366608 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0366333 |
| ATOSA | atos homolog A | -0.0364962 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0364241 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0363571 |
| PTMA | prothymosin, alpha | -0.0360519 |
| VCL | vinculin | -0.0356978 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0354677 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0349915 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0346439 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.034576 |
| JMJD1C | jumonji domain containing 1C | -0.0344563 |
| MYO6 | myosin VI | -0.0343321 |
| OSMR | oncostatin M receptor | -0.0340371 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0339879 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0335604 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0324372 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0321588 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0309897 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.030705 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0304098 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303399 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0299149 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0294906 |
| CP | ceruloplasmin (ferroxidase) | -0.0293176 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0292672 |
| TJP2 | tight junction protein 2 | -0.0287609 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0286881 |
| FOXO3 | forkhead box O3 | -0.0285527 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0282158 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0281451 |
| GLIS3 | GLIS family zinc finger 3 | -0.0281261 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0278604 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0277617 |
| VCAN | versican | -0.0277386 |
| TXNRD1 | thioredoxin reductase 1 | -0.0276783 |
| FOXP1 | forkhead box P1 | -0.0274157 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0273583 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0272981 |
| MED13L | mediator complex subunit 13-like | -0.0272655 |
| TCF12 | transcription factor 12 | -0.0272341 |
| ZNF217 | zinc finger protein 217 | -0.0269614 |
| FOXO1 | forkhead box O1 | -0.0269312 |
| CUX1 | cut-like homeobox 1 | -0.0267264 |
| TMEM165 | transmembrane protein 165 | -0.0265684 |
| PLIN3 | perilipin 3 | -0.026205 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0261905 |
| ACTG1 | actin gamma 1 | -0.0260203 |
| ANXA11 | annexin A11 | -0.0259457 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0258755 |
| EGFR | epidermal growth factor receptor | -0.025864 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0257486 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0255848 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.025411 |
| DENND2C | DENN/MADD domain containing 2C | -0.0252819 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0247258 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0246989 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.024652 |
| RNF145 | ring finger protein 145 | -0.0244471 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0244457 |
| HMGA2 | high mobility group AT-hook 2 | -0.0243934 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0241118 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0240525 |
| SMYD3 | SET and MYND domain containing 3 | -0.023844 |
| MYO5C | myosin VC | -0.0235189 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0234103 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0234042 |
| CD44 | CD44 molecule (Indian blood group) | -0.0233945 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0233426 |
