| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.113918 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.109833 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.102066 |
| RACK1 | receptor for activated C kinase 1 | 0.0842025 |
| TMSB10 | thymosin beta 10 | 0.0837157 |
| RPL26 | ribosomal protein L26 | 0.0821817 |
| RPL23 | ribosomal protein L23 | 0.0820737 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0809844 |
| RPS12 | ribosomal protein S12 | 0.0782414 |
| RPS3 | ribosomal protein S3 | 0.0780387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0748588 |
| RPL3 | ribosomal protein L3 | 0.0739862 |
| ASPH | aspartate beta-hydroxylase | 0.0739354 |
| RPL12 | ribosomal protein L12 | 0.0721899 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0715089 |
| TXNRD1 | thioredoxin reductase 1 | 0.0708078 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0686995 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0606703 |
| RPS4X | ribosomal protein S4, X-linked | 0.060181 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0561753 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0547397 |
| NEK7 | NIMA-related kinase 7 | 0.0510647 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0503805 |
| MYOF | myoferlin | 0.0485085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0484709 |
| TPI1 | triosephosphate isomerase 1 | 0.0478913 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0475387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0471547 |
| MT2A | metallothionein 2A | 0.0469588 |
| KYNU | kynureninase | 0.0467339 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0466853 |
| GRAMD1B | GRAM domain containing 1B | 0.0455881 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0447894 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.044523 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0442721 |
| RPL11 | ribosomal protein L11 | 0.04396 |
| RPL18 | ribosomal protein L18 | 0.0427726 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0422512 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0419914 |
| EZR | ezrin | 0.0416999 |
| CTSC | cathepsin C | 0.0412935 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0411076 |
| CD109 | CD109 molecule | 0.0391003 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0382857 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0379018 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0377724 |
| RGS2 | regulator of G-protein signaling 2 | 0.0377379 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.037588 |
| RTN4 | reticulon 4 | 0.037191 |
| RPS17 | ribosomal protein S17 | 0.0364818 |
| INHBA | inhibin, beta A | 0.0359408 |
| LDHA | lactate dehydrogenase A | 0.0357085 |
| FLNB | filamin B, beta | 0.0356565 |
| B2M | beta-2-microglobulin | 0.0354353 |
| GDA | guanine deaminase | 0.0351014 |
| PYGL | phosphorylase, glycogen, liver | 0.0345405 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0340836 |
| MFF | mitochondrial fission factor | 0.0328289 |
| RPL4 | ribosomal protein L4 | 0.03194 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.031217 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0311087 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0308204 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0306706 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0302895 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0301874 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0301416 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0300634 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0295536 |
| RPS19 | ribosomal protein S19 | 0.0293399 |
| RPL37 | ribosomal protein L37 | 0.0288601 |
| RPL9 | ribosomal protein L9 | 0.0287363 |
| RAI1 | retinoic acid induced 1 | 0.0282062 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0277463 |
| YBX1 | Y box binding protein 1 | 0.0276839 |
| FTL | ferritin, light polypeptide | 0.0274868 |
| RPL30 | ribosomal protein L30 | 0.0273212 |
| TPM3 | tropomyosin 3 | 0.0272375 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0271357 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0265943 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0265238 |
| DUSP4 | dual specificity phosphatase 4 | 0.0264337 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0262502 |
| ENAH | enabled homolog (Drosophila) | 0.0261186 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0259936 |
| RPLP0 | ribosomal protein, large, P0 | 0.0259696 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0257796 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0257371 |
| RPL36 | ribosomal protein L36 | 0.0257069 |
| ANXA1 | annexin A1 | 0.025659 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.025651 |
| RPL37A | ribosomal protein L37a | 0.0255034 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0252146 |
| YBX3 | Y box binding protein 3 | 0.0248378 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0243865 |
| ARRDC3 | arrestin domain containing 3 | 0.0241834 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0237261 |
| KRT19 | keratin 19, type I | 0.0236791 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0234108 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0233807 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0232112 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.194785 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.182686 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.110171 |
| CDH13 | cadherin 13 | -0.109186 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0856336 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0843058 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0815805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0737307 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0723429 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0659062 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0564824 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0554938 |
| RPS23 | ribosomal protein S23 | -0.0536066 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0512596 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0499251 |
| CUX1 | cut-like homeobox 1 | -0.0498465 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0495184 |
| RPL38 | ribosomal protein L38 | -0.0491451 |
| RPL35A | ribosomal protein L35a | -0.0466951 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0454725 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0446118 |
| NBEAL1 | neurobeachin-like 1 | -0.0442262 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0440248 |
| RPS25 | ribosomal protein S25 | -0.0407376 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0406243 |
| RPL7A | ribosomal protein L7a | -0.0401807 |
| INTS6 | integrator complex subunit 6 | -0.0399383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0387928 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0384634 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0366044 |
| HLA-B | major histocompatibility complex, class I, B | -0.036387 |
| RAD51B | RAD51 paralog B | -0.035941 |
| VIM | vimentin | -0.0349044 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0342153 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.033031 |
| DENND1A | DENN/MADD domain containing 1A | -0.0326512 |
| AUTS2 | autism susceptibility candidate 2 | -0.0326396 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0324716 |
| RPS6 | ribosomal protein S6 | -0.0320495 |
| RPS15 | ribosomal protein S15 | -0.0319733 |
| RPS29 | ribosomal protein S29 | -0.0311216 |
| VCL | vinculin | -0.0302794 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0301344 |
| CADM2 | cell adhesion molecule 2 | -0.0299361 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0290806 |
| RPS13 | ribosomal protein S13 | -0.0290598 |
| SQSTM1 | sequestosome 1 | -0.0290245 |
| S100A10 | S100 calcium binding protein A10 | -0.0287547 |
| RPS21 | ribosomal protein S21 | -0.028525 |
| PRELID2 | PRELI domain containing 2 | -0.0282819 |
| XYLT1 | xylosyltransferase I | -0.0275846 |
| MAP7 | microtubule-associated protein 7 | -0.0271271 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0270876 |
| TENM3 | teneurin transmembrane protein 3 | -0.0270029 |
| PDE10A | phosphodiesterase 10A | -0.0267433 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0266763 |
| FUS | FUS RNA binding protein | -0.0265584 |
| AEBP2 | AE binding protein 2 | -0.0265471 |
| CANX | calnexin | -0.0265103 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0264592 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0263186 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0259009 |
| ACTG1 | actin gamma 1 | -0.0256473 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0254528 |
| PCDH15 | protocadherin-related 15 | -0.0252161 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0250001 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0249006 |
| RPS16 | ribosomal protein S16 | -0.0247846 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0247057 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0243236 |
| RPS24 | ribosomal protein S24 | -0.0231251 |
| RPS11 | ribosomal protein S11 | -0.0230674 |
| NCKAP5 | NCK-associated protein 5 | -0.0228504 |
| RPS10 | ribosomal protein S10 | -0.0228106 |
| COL5A2 | collagen, type V, alpha 2 | -0.0227599 |
| SCFD1 | sec1 family domain containing 1 | -0.0226158 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0224843 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0223019 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0222406 |
| SVIL | supervillin | -0.0220895 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0216935 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0216379 |
| FNIP1 | folliculin interacting protein 1 | -0.0214974 |
| AGR2 | anterior gradient 2 | -0.0212816 |
| RPL28 | ribosomal protein L28 | -0.0212119 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0210859 |
| RPLP2 | ribosomal protein, large, P2 | -0.0210524 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0209926 |
| USP34 | ubiquitin specific peptidase 34 | -0.0209896 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0209601 |
| KPNB1 | karyopherin (importin) beta 1 | -0.020567 |
| CALR | calreticulin | -0.0204805 |
| KIAA0825 | KIAA0825 | -0.0202965 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.02027 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0201358 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0201247 |
| PTMA | prothymosin, alpha | -0.0200464 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0200379 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0198499 |
| LSAMP | limbic system-associated membrane protein | -0.0197462 |
