| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.147022 |
| VIM | vimentin | 0.137823 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.12745 |
| FNDC3B | fibronectin type III domain containing 3B | 0.119783 |
| MT2A | metallothionein 2A | 0.106239 |
| CDH13 | cadherin 13 | 0.104082 |
| FN1 | fibronectin 1 | 0.0987341 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0978566 |
| PDE10A | phosphodiesterase 10A | 0.0976082 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0968256 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0891922 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0842212 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0839106 |
| NDRG1 | N-myc downstream regulated 1 | 0.0809918 |
| ENO1 | enolase 1, (alpha) | 0.0789191 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0788306 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0764725 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0743733 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0733193 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0686403 |
| GLIS3 | GLIS family zinc finger 3 | 0.0677789 |
| MYOF | myoferlin | 0.06485 |
| EFNA5 | ephrin-A5 | 0.0641588 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0625669 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0625015 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0610881 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0608632 |
| MYO1E | myosin IE | 0.0605077 |
| RPS6 | ribosomal protein S6 | 0.0592023 |
| LAMA4 | laminin, alpha 4 | 0.0534705 |
| YBX3 | Y box binding protein 3 | 0.0528037 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0515532 |
| RACK1 | receptor for activated C kinase 1 | 0.048821 |
| AHNAK | AHNAK nucleoprotein | 0.0477503 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0476281 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0463991 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0456156 |
| SLTM | SAFB-like, transcription modulator | 0.0444648 |
| GOLGA4 | golgin A4 | 0.0441379 |
| EHBP1 | EH domain binding protein 1 | 0.0439601 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0439318 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0422857 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0421165 |
| RPS8 | ribosomal protein S8 | 0.0419811 |
| TMSB10 | thymosin beta 10 | 0.0414817 |
| RPLP1 | ribosomal protein, large, P1 | 0.0409919 |
| SEPTIN9 | septin 9 | 0.0401331 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0395113 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.039007 |
| ASPH | aspartate beta-hydroxylase | 0.0382883 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0381883 |
| DOCK5 | dedicator of cytokinesis 5 | 0.038017 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0374437 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0373362 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0359713 |
| SPAG9 | sperm associated antigen 9 | 0.03554 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0341987 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0318364 |
| INHBA | inhibin, beta A | 0.0314 |
| EGFR | epidermal growth factor receptor | 0.0305976 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302173 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0295683 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0291714 |
| EZR | ezrin | 0.028667 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0283986 |
| FMNL2 | formin-like 2 | 0.0282711 |
| LMNA | lamin A/C | 0.0273468 |
| OXR1 | oxidation resistance 1 | 0.0269827 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0267374 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.026382 |
| CANX | calnexin | 0.0263814 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0261523 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0261393 |
| RUNX1 | runt-related transcription factor 1 | 0.0258205 |
| RPL26 | ribosomal protein L26 | 0.0255427 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0249056 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0245576 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0244084 |
| MEF2A | myocyte enhancer factor 2A | 0.0210399 |
| FRMD4A | FERM domain containing 4A | 0.0207378 |
| RASA3 | RAS p21 protein activator 3 | 0.0207062 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0206564 |
| B2M | beta-2-microglobulin | 0.0206469 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0192523 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0191634 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0188805 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0172287 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0162665 |
| SLK | STE20-like kinase | 0.0161804 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0161526 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0160157 |
| RPL35A | ribosomal protein L35a | 0.0158912 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0153384 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0152887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0151399 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0149479 |
| NF1 | neurofibromin 1 | 0.0143786 |
| LAMB3 | laminin, beta 3 | 0.0137203 |
| TPM4 | tropomyosin 4 | 0.0134302 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.0130568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259582 |
| UBC | ubiquitin C | -0.140101 |
| PTMA | prothymosin, alpha | -0.131541 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0958517 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0855126 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0825266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0821292 |
| RPL31 | ribosomal protein L31 | -0.0797493 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0796387 |
| NUP58 | nucleoporin 58 | -0.0794765 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0780972 |
| ACTN4 | actinin, alpha 4 | -0.0772919 |
| RNF213 | ring finger protein 213 | -0.074631 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0719727 |
| SRPK2 | SRSF protein kinase 2 | -0.0705455 |
| SMYD3 | SET and MYND domain containing 3 | -0.0701865 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0700256 |
| RLF | rearranged L-myc fusion | -0.0674192 |
| SETD5 | SET domain containing 5 | -0.0660339 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0650828 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0642802 |
| GPC6 | glypican 6 | -0.063338 |
| HDLBP | high density lipoprotein binding protein | -0.0623427 |
| HDAC9 | histone deacetylase 9 | -0.0621894 |
| MCL1 | myeloid cell leukemia 1 | -0.0620885 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0615843 |
| RTN4 | reticulon 4 | -0.0609015 |
| TXNIP | thioredoxin interacting protein | -0.0605905 |
| ANXA2 | annexin A2 | -0.0577504 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0567072 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0566208 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0554627 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0552568 |
| MAP4 | microtubule-associated protein 4 | -0.0542063 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0533494 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0533404 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0530327 |
| CCNI | cyclin I | -0.0524911 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | -0.0519119 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0515461 |
| COG5 | component of oligomeric golgi complex 5 | -0.0509405 |
| LDHA | lactate dehydrogenase A | -0.050104 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0471599 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0465718 |
| USP34 | ubiquitin specific peptidase 34 | -0.0463683 |
| RPL23 | ribosomal protein L23 | -0.0449254 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0448818 |
| PARD3 | par-3 family cell polarity regulator | -0.0447824 |
| MORF4L2 | mortality factor 4 like 2 | -0.0445921 |
| MYO6 | myosin VI | -0.0445487 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0445052 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.043265 |
| RPS27A | ribosomal protein S27a | -0.0427477 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0426481 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0408735 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0406212 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0405775 |
| VMP1 | vacuole membrane protein 1 | -0.0403387 |
| ACTG1 | actin gamma 1 | -0.0393185 |
| DST | dystonin | -0.0388738 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0386177 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0382347 |
| NRG3 | neuregulin 3 | -0.0378403 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0367229 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0355085 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0350458 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0330215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0318714 |
| GPHN | gephyrin | -0.0308042 |
| MED13L | mediator complex subunit 13-like | -0.0305341 |
| ZNF292 | zinc finger protein 292 | -0.0295584 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.028339 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0281192 |
| RAB7A | RAB7A, member RAS oncogene family | -0.02796 |
| HLA-B | major histocompatibility complex, class I, B | -0.0261895 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0256838 |
| TPI1 | triosephosphate isomerase 1 | -0.0249893 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0248762 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0244319 |
| COPA | coatomer protein complex, subunit alpha | -0.0228717 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0210769 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.020741 |
| TXNRD1 | thioredoxin reductase 1 | -0.0201676 |
| JMJD1C | jumonji domain containing 1C | -0.0191661 |
| NLGN1 | neuroligin 1 | -0.0187956 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0186782 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0162804 |
| PKM | pyruvate kinase, muscle | -0.0162368 |
| RBM25 | RNA binding motif protein 25 | -0.0159531 |
| PTK2 | protein tyrosine kinase 2 | -0.0146593 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0145493 |
| ATXN1 | ataxin 1 | -0.0145329 |
| PGK1 | phosphoglycerate kinase 1 | -0.0143589 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0142554 |
| RPL37A | ribosomal protein L37a | -0.0141286 |
| PDE8A | phosphodiesterase 8A | -0.0138541 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0135884 |
| SLC38A1 | solute carrier family 38, member 1 | -0.013531 |
| FMN1 | formin 1 | -0.0121369 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0117973 |
