| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diammonium Glycyrrhizinate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diammonium Glycyrrhizinate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.140268 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0661263 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0629211 |
| NDRG1 | N-myc downstream regulated 1 | 0.0603454 |
| AHNAK | AHNAK nucleoprotein | 0.0603058 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0478744 |
| PTMA | prothymosin, alpha | 0.0454217 |
| EZR | ezrin | 0.0414848 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0414003 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0402981 |
| SMAD3 | SMAD family member 3 | 0.0396076 |
| MYO6 | myosin VI | 0.0392073 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.038719 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.038254 |
| OGA | O-GlcNAcase | 0.036789 |
| CANX | calnexin | 0.0356398 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0353311 |
| NAV2 | neuron navigator 2 | 0.0343452 |
| FMNL2 | formin-like 2 | 0.0338777 |
| SQSTM1 | sequestosome 1 | 0.0333829 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0323009 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0321376 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320529 |
| PLEC | plectin | 0.0307866 |
| RPL23 | ribosomal protein L23 | 0.0282431 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0275695 |
| ARRDC3 | arrestin domain containing 3 | 0.0274732 |
| ATF3 | activating transcription factor 3 | 0.0272997 |
| BRD2 | bromodomain containing 2 | 0.0270811 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0270551 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0265966 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0251881 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246127 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.024427 |
| RLF | rearranged L-myc fusion | 0.0242482 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0237369 |
| BRD4 | bromodomain containing 4 | 0.0234913 |
| RPL13A | ribosomal protein L13a | 0.0233621 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0228187 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0225272 |
| FOXO3 | forkhead box O3 | 0.0224756 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0216666 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0213194 |
| RPS12 | ribosomal protein S12 | 0.0210981 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.02108 |
| G0S2 | G0/G1 switch 2 | 0.0206663 |
| KIAA1671 | KIAA1671 | 0.0206129 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.020522 |
| MATR3 | matrin 3 | 0.0205189 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0204471 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0204435 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0203773 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0203618 |
| YAP1 | Yes-associated protein 1 | 0.0202971 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0201205 |
| ABHD3 | abhydrolase domain containing 3 | 0.0198692 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0197867 |
| CTBP2 | C-terminal binding protein 2 | 0.0195663 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0193329 |
| RPL4 | ribosomal protein L4 | 0.01929 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0192323 |
| FAM107B | family with sequence similarity 107, member B | 0.0192065 |
| XPO1 | exportin 1 | 0.0191768 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0191015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0188734 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0188664 |
| ZNF292 | zinc finger protein 292 | 0.0187936 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187877 |
| RPL3 | ribosomal protein L3 | 0.018653 |
| RBM39 | RNA binding motif protein 39 | 0.0185835 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0185661 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0184695 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0184675 |
| CEP350 | centrosomal protein 350kDa | 0.0182936 |
| ATP11A | ATPase, class VI, type 11A | 0.0181941 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0180931 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0180351 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0177547 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.017743 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0175725 |
| PDE8A | phosphodiesterase 8A | 0.0175047 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0174885 |
| ZNF451 | zinc finger protein 451 | 0.0172881 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0172693 |
| ADM | adrenomedullin | 0.0171301 |
| SLTM | SAFB-like, transcription modulator | 0.0170475 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0170113 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0170034 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0169826 |
| RPS27 | ribosomal protein S27 | 0.0169495 |
| ATP11B | ATPase, class VI, type 11B | 0.0169236 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0167529 |
| FAM13A | family with sequence similarity 13, member A | 0.0166439 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0166317 |
| ZNF217 | zinc finger protein 217 | 0.0165675 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0165587 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0165484 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0165146 |
| CDYL | chromodomain protein, Y-like | 0.0165061 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0164477 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236207 |
| LAMA4 | laminin, alpha 4 | -0.153863 |
| MUC4 | mucin 4, cell surface associated | -0.146328 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.100874 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0939548 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.088149 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0845923 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.084206 |
| TMSB10 | thymosin beta 10 | -0.0823199 |
| TMSB4X | thymosin beta 4, X-linked | -0.0700599 |
| KRT19 | keratin 19, type I | -0.0688863 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0672238 |
| KRT7 | keratin 7, type II | -0.0665914 |
| MUC16 | mucin 16, cell surface associated | -0.0641765 |
| POTEF | POTE ankyrin domain family, member F | -0.0619172 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0616647 |
| OSMR | oncostatin M receptor | -0.0609606 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0608563 |
| PLAT | plasminogen activator, tissue | -0.0600145 |
| RNF213 | ring finger protein 213 | -0.0584096 |
| VCL | vinculin | -0.0580567 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0575608 |
| HMGA1 | high mobility group AT-hook 1 | -0.0570323 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0562977 |
| PLSCR1 | phospholipid scramblase 1 | -0.0558233 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.05522 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.053714 |
| ACTG1 | actin gamma 1 | -0.0535595 |
| LAMC2 | laminin, gamma 2 | -0.0496027 |
| RPS21 | ribosomal protein S21 | -0.0493137 |
| C3 | complement component 3 | -0.0485739 |
| MX2 | MX dynamin-like GTPase 2 | -0.04841 |
| KRT8 | keratin 8, type II | -0.0480383 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.046625 |
| FN1 | fibronectin 1 | -0.0459939 |
| DSG2 | desmoglein 2 | -0.0459484 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.04587 |
| EGR1 | early growth response 1 | -0.0451231 |
| S100A6 | S100 calcium binding protein A6 | -0.0448097 |
| ASPH | aspartate beta-hydroxylase | -0.0439774 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.043432 |
| CD2AP | CD2-associated protein | -0.0431043 |
| ETV6 | ets variant 6 | -0.042124 |
| CD44 | CD44 molecule (Indian blood group) | -0.0416637 |
| MX1 | MX dynamin-like GTPase 1 | -0.0414008 |
| RASAL2 | RAS protein activator like 2 | -0.0387013 |
| IFI44 | interferon-induced protein 44 | -0.0369082 |
| MYO1E | myosin IE | -0.0368791 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0350538 |
| B2M | beta-2-microglobulin | -0.0346298 |
| EFNA5 | ephrin-A5 | -0.0346287 |
| RIGI | RNA sensor RIG-I | -0.0334515 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0329851 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0324531 |
| RAD51B | RAD51 paralog B | -0.0321711 |
| MT2A | metallothionein 2A | -0.0315326 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0312236 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0311411 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0307052 |
| HLA-B | major histocompatibility complex, class I, B | -0.0306605 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0305277 |
| LMO7 | LIM domain 7 | -0.0304503 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0303812 |
| S100A9 | S100 calcium binding protein A9 | -0.030127 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0301099 |
| TAPBP | TAP binding protein (tapasin) | -0.0300365 |
| VMP1 | vacuole membrane protein 1 | -0.0298962 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.029509 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0295038 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0291616 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0289201 |
| MACC1 | metastasis associated in colon cancer 1 | -0.028839 |
| IFI44L | interferon-induced protein 44-like | -0.0287478 |
| EHBP1 | EH domain binding protein 1 | -0.0287288 |
| IL6ST | interleukin 6 signal transducer | -0.028584 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0285553 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0284772 |
| RPS24 | ribosomal protein S24 | -0.0284663 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0275454 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0274237 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0273362 |
| PDLIM5 | PDZ and LIM domain 5 | -0.027172 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0270941 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0268392 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0267663 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267265 |
| WWC1 | WW and C2 domain containing 1 | -0.0266119 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0265872 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0259868 |
| ITGA6 | integrin, alpha 6 | -0.0259819 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0258965 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.0258487 |
| RPL32 | ribosomal protein L32 | -0.0258337 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0258321 |
| SGMS2 | sphingomyelin synthase 2 | -0.02583 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0257258 |
| PLPP6 | phospholipid phosphatase 6 | -0.0257085 |
| MELTF | melanotransferrin | -0.025587 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0255858 |
| VIM | vimentin | -0.0255585 |
